JonathanChernoffMD

PubMed

• KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation.
  Konstantin Budyagan, Alexa C Cannon, Adam Chatoff, Nathaniel W Snyder, Alison M Kurimchak, James S Duncan, Jonathan Chernoff> ;Research Square. 2024 Feb 22
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
  Cannon, A., Budagyan, K., Uribe-Alvarez, C., Kurimchak, A., Araiza-Olivera, D., Cai, K., Peri, S., Zhou, Y., Duncan, J., Chernoff, J.> ;Oncogene. 2024 Mar 1
• A Facile Method to Append a Bio-ID Tag to Endogenous Mutant Kras Alleles.
  Konstantin Budagyan, Alexa C Cannon, Jonathan Chernoff> ;Methods in Molecular Biology. 2024 Jan 1
• RHOA drivers take alternate routes in gastric cancer.
  Benton, D., Chernoff, J.> ;Science Signaling. 2023 Dec 19
• A PTP1B-Cdk3 Signaling Axis Promotes Cell Cycle Progression of Human Glioblastoma Cells through an Rb-E2F Dependent Pathway.
  Olga Villamar-Cruz, Marco Antonio Loza-Mejía, Alonso Vivar-Sierra, Héctor Iván Saldivar-Cerón, Genaro Patiño-López, Jonadab Efraín Olguín, Luis Ignacio Terrazas, Leone...> ;Molecular and Cellular Biology. 2023 Jan 1
• 1 citations
  TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway.
  Dorothy Benton, Jonathan Chernoff> ;Cell Chemical Biology. 2023 Jul 20
• Unique vulnerability of-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
  Alexa C Cannon, Konstantin Budagyan, Cristina Uribe-Alvarez, Alison M Kurimchak, Daniela Araiza-Olivera, Kathy Q Cai, Suraj Peri, Yan Zhou, James S Duncan, Jonathan Ch...> ;Biorxiv. 2023 Jun 28
• 4 citations
  Development and Utility of a PAK1-Selective Degrader.
  Hoi-Yee Chow, Sofiia Karchugina, Brian J Groendyke, Sean Toenjes, John Hatcher, Katherine A Donovan, Eric S Fischer, Gleb Abalakov, Bulat Faezov, Roland Dunbrack, Nath...> ;Journal of Medicinal Chemistry. 2022 Dec 8
• 3 citations
  Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation.
  Mahesh Kathania, Ritesh Kumar, Elviche Taskem Lenou, Venkatesha Basrur, Arianne L Theiss, Jonathan Chernoff, K Venuprasad> ;Cell Reports. 2022 Sep 13
• 5 citations
  Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
  Eleonora Sementino, Yuwaraj Kadariya, Mitchell Cheung, Craig W Menges, Yinfei Tan, Anna-Mariya Kukuyan, Ujjawal Shrestha, Sofiia Karchugina, Kathy Q Cai, Suraj Peri, J...> ;Molecular Cancer Research. 2022 May 4
• 2 citations
  Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy.
  Namrita Kaur, Andrea Ruiz-Velasco, Rida Raja, Gareth Howell, Jessica M Miller, Riham R E Abouleisa, Qinghui Ou, Kimberly Mace, Susanne S Hille, Norbert Frey, Pablo Bin...> ;Iscience. 2022 Mar 18
• 11 citations
  Pak2 Regulation of Nrf2 Serves as a Novel Signaling Nexus Linking ER Stress Response and Oxidative Stress in the Heart.
  Pablo Binder, Binh Nguyen, Lucy Collins, Min Zi, Wei Liu, Foteini Christou, Xiaojing Luo, Susanne S Hille, Norbert Frey, Elizabeth J Cartwright, Jonathan Chernoff, Oli...> ;Frontiers in Cardiovascular Medicine. 2022 Jan 1
• 6 citations
  The two-hit theory hits 50.
  Jonathan Chernoff> ;Molecular Biology of the Cell. 2021 Dec 1
• 9 citations
  PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
  Eric T. Hawley, Jeff R. Gehlhausen, Sofiia Karchugina, Hoi-Yee Chow, Daniela Araiza-Olivera, Maria Radu, Abbi Smith, Ciersten Burks, Li Jiang, Xiaohong Li, Waylan K. B...> ;Human Molecular Genetics. 2021 Aug 12
• 26 citations
  Low saliva pH can yield false positives results in simple RT-LAMP-based SARS-CoV-2 diagnostic tests.
  Cristina Uribe-Alvarez, Quynh Lam, Don A. Baldwin, Jonathan Chernoff> ;Plos One. 2021 May 5
• 2020 in 20/20 hindsight.
  Jonathan Chernoff> ;Molecular Biology of the Cell. 2021 May 1
• 6 citations
  Regulation of MST complexes and activity via SARAH domain modifications.
  Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff> ;Biochemical Society Transactions. 2021 Apr 30
• 5 citations
  p21-Activated Kinase 1 Promotes Breast TumorigenesisPhosphorylation and Activation of the Calcium/Calmodulin-Dependent Protein Kinase II.
  Héctor I Saldivar-Cerón, Olga Villamar-Cruz, Claire M Wells, Ibrahim Oguz, Federica Spaggiari, Jonathan Chernoff, Genaro Patiño-López, Sara Huerta-Yepez, Mayra Monteci...> ;Frontiers in Cell and Developmental Biology. 2021 Jan 1
• A Facile Method to Engineer Mutant Kras Alleles in an Isogenic Cell Background.
  Konstantin Budagyan, Jonathan Chernoff> ;Methods in Molecular Biology. 2021 Jan 1
• 31 citations
  RAC1 as a Therapeutic Target in Malignant Melanoma.
  Alexa C. Cannon, Cristina Uribe-Alvarez, Jonathan Chernoff> ;Trends in Cancer. 2020 Jun 1
• 15 citations
  Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma
  Alison Kurimchak, Carlos Herrera-Montávez, Jennifer Brown, Katherine J. Johnson, Valerie L. Sodi, Nishi Srivastava, Vikas Kumar, Safoora Deihimi, Shane W. O'Brien, Sur...> ;Science Signaling. 2020 Feb 18
• 10 citations
  Targeting effector pathways in RAC1P29S-driven malignant melanoma.
  Cristina Uribe-Alvarez, Sandra L. Guerrero-Rodríguez, Jennifer Rhodes, Alexa C. Cannon, Jonathan Chernoff, Daniela Araiza-Olivera> ;Small Gtpases. 2021 Jul 4
• 2 citations
  A New Rho(d) Map to Diffuse Gastric Cancer.
  Dorothy Benton, Jonathan Chernoff> ;Cancer Discovery. 2020 Feb 1
• 2 citations
  Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2)
  Yu-chi Shen, Caroline Arellano-Garcia, Rosa E. Menjivar, Ethan M. Jewett, Wolfgang Dohle, Sofiia Karchugina, Jonathan Chernoff, Barry V. L. Potter, Kate F. Barald> ;BMC Pharmacology & Toxicology. 2019 Nov 15
• How much is my paper worth
  Jonathan Chernoff> ;Molecular Biology of the Cell. 2019 Nov 1
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