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Office
55 Fruit St
Boston, MA 02114Phone+1 617-726-2000- Is this information wrong?
Summary
- I'm a Gastroenterology Fellow at Massachusetts General Hospital. I'm a graduate of the Internal Medicine/Stanbury Physician-Scientist Pathway Resident Physician at Massachusetts General Hospital. I'm particularly interested in genomic medicine, personalized healthcare, human genetics, and functional genomics in gastroenterology. My current research focus is on how genetic, epigenetic, and environmental factors influence the development of gastrointestinal dysplasia and malignancy.
I'm an alumnus of the MD, PhD program at the University of Utah School of Medicine. I have my PhD in Human Genetics (Lynn Jorde Lab). The primary focus of my research included population genetics and genomics. Specifically, I studied the genetic mechanisms that have allowed Tibetan populations to adapt to a high altitude environment. I also did work investigating how genetic risk factors play a role in amyotrophic lateral sclerosis pathogenesis and other clinical disorders.
Education & Training
- Massachusetts General HospitalFellowship, Gastroenterology, 2021 - 2025
- Massachusetts General HospitalResidency, Internal Medicine, 2019 - 2021
- University of Utah School of MedicineClass of 2019, MD, PhD, AOA
- University of UtahBS, Biology, Mountain West Conference Scholar Athlete Award (2008, 2009), 2006 - 2009
Certifications & Licensure
- MA State Medical License 2019 - 2024
- American Board of Internal Medicine Internal Medicine
Publications & Presentations
PubMed
- 1 citationsIncident Cancer Risk and Signatures Among Older MUTYH Carriers: Analysis of Population-Based and Genomic Cohorts.Jonathan M Downie, Moeen Riaz, Jing Xie, Minyi Lee, Andrew T Chan, Peter Gibbs, Suzanne G Orchard, Suzanne E Mahady, Robert P Sebra, Anne M Murray, Finlay Macrae, Eric...> ;Cancer Prevention Research. 2022 Aug 1
- 4 citationsAssociation of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia.David Spencer Mangum, Julia Meyer, Clinton C. Mason, Soheil Shams, Luke Maese, Jamie D. Gardiner, Jonathan M. Downie, Deqing Pei, Cheng Cheng, Adam Gleason, Minjie Luo...> ;JAMA Oncology. 2021 Oct 1
- 9 citationsPathogenic effect of TP73 Gene Variants in People With Amyotrophic Lateral SclerosisKristi L. Russell, Jonathan M. Downie, Summer Gibson, Spyridoula Tsetsou, Matthew D. Keefe, Jerry A. Duran, Karla P. Figueroa, Mark B. Bromberg, L. Charles Murtaugh, J...> ;Neurology. 2021 Jun 16
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