KeithAJosephsMD

PubMed

• Clinical Utility of Tectal Plate Measurements on Magnetic Resonance Imaging in Progressive Supranuclear Palsy.
  Abigail Amrami, Neha Atulkumar Singh, Nha Trang Thu Pham, Yehkyoung C Stephens, Jennifer L Whitwell, Farwa Ali, Keith A Josephs> ;Movement Disorders. 2024 Apr 8
• Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech.
  Danna P Garcia-Guaqueta, Rene L Utianski, Joseph R Duffy, Austin W Goodrich, Nha Trang Thu Pham, Mary M Machulda, Matt Baker, Rosa Rademakers, Jennifer L Whitwell, Hug...> ;Journal of Neurology. 2024 Apr 7
• A multimodal clinical diagnostic approach using MRI andF-FDG-PET for antemortem diagnosis of TDP-43 in cases with low-intermediate Alzheimer's disease neuropathologic ...
  Nha Trang Thu Pham, Cynthia J Vernon, Dennis W Dickson, Clifford R Jack Jr, Jennifer L Whitwell, Anna Lavrova, Arenn F Carlos, Ronald C Petersen, Val J Lowe, Keith A J...> ;Journal of Neurology. 2024 Apr 5
• Primary Progressive Apraxia of Speech Caused by TDP-43: A Case Report.
  Gabriela Meade, Jennifer L Whitwell, Dennis W Dickson, Joseph R Duffy, Heather M Clark, J Eric Ahlskog, Mary M Machulda, Rene L Utianski, Keith A Josephs> ;Neurology. Genetics. 2024 Apr 1
• 1 citations
  Atypical Alzheimer's disease: new insights into an overlapping spectrum between the language and visual variants.
  Neha Atulkumar Singh, Mary M Machulda, Christopher G Schwarz, Matthew L Senjem, Clifford R Jack Jr, Jennifer L Whitwell, Jonathan Graff-Radford, Arenn F Carlos, Val J ...> ;Journal of Neurology. 2024 Mar 29
• HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
  Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael D...> ;Molecular Neurodegeneration. 2024 Mar 27
• Plasma glial fibrillary acidic protein in the visual and language variants of Alzheimer's disease.
  Irene Sintini, Neha Atulkumar Singh, Danni Li, Michelle M Mielke, Mary M Machulda, Christopher G Schwarz, Matthew L Senjem, Clifford R Jack Jr, Jennifer L Whitwell, Va...> ;Alzheimer's & Dementia. 2024 Mar 25
• Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology.
  Carling G Robinson, Austin W Goodrich, Stephen D Weigand, Nha Trang Thu Pham, Melissa E Murray, R Ross Reichard, Dennis W Dickson, Rene L Utianski, Jennifer L Whitwell...> ;Journal of the International Neuropsychological Society. 2024 Mar 25
• Clinicoradiological and neuropathological evaluation of primary progressive aphasia.
  Dror Shir, Nick Corriveau-Lecavalier, Camilo Bermudez Noguera, Leland Barnard, Nha Trang Thu Pham, Hugo Botha, Joseph R Duffy, Heather M Clark, Rene L Utianski, David ...> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2024 Mar 21
• Altered structural and functional connectivity in Posterior Cortical Atrophy and Dementia with Lewy bodies.
  Neha Atulkumar Singh, Austin W Goodrich, Jonathan Graff-Radford, Mary M Machulda, Irene Sintini, Arenn F Carlos, Carling G Robinson, Robert I Reid, Val J Lowe, Cliffor...> ;Neuroimage. 2024 Apr 15
• Significance of a positive tau PET scan with a negative amyloid PET scan.
  Carling G Robinson, Jeyeon Lee, Paul H Min, Scott A Przybelski, Keith A Josephs, David T Jones, Jonathan Graff-Radford, Bradley F Boeve, David S Knopman, Clifford R Ja...> ;Alzheimer's & Dementia. 2024 Mar 1
• Characterizing Speech Errors Across Primary Progressive Apraxia of Speech Subtypes.
  Katerina A Tetzloff, Joseph R Duffy, Heather M Clark, Keith A Josephs, Jennifer L Whitwell, Rene L Utianski> ;Journal of Speech, Language, and Hearing Research. 2024 Mar 11
• 2 citations
  Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-an...
  Marianne Chapleau, Renaud La Joie, Keir Yong, Federica Agosta, Isabel Elaine Allen, Liana Apostolova, John Best, Baayla D C Boon, Sebastian Crutch, Massimo Filippi, Gi...> ;The Lancet. Neurology. 2024 Feb 1
• TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.
  Marks, J., Ayuso, V., Carlomagno, Y., Yue, M., Todd, T., Hao, Y., Li, Z., McEachin, Z., Shantaraman, A., Duong, D., Daughrity, L., Jansen-West, K., Shao, W., Calliari,...> ;Science Translational Medicine. 2024 Jan 17
• Longitudinal flortaucipir, metabolism and volume differ between phonetic and prosodic speech apraxia.
  Tetzloff, K., Martin, P., Duffy, J., Utianski, R., Machulda, M., Thu Pham, N., Schwarz, C., Senjem, M., Jack, C., Whitwell, J., Clark, H., Botha, H., Lowe, V., Josephs...> ;Brain. 2024 Jan 13
• Direct comparison betweenF-Flortaucipir tau PET and quantitative susceptibility mapping in progressive supranuclear palsy.
  Satoh, R., Whitwell, J., Ali, F., Botha, H., Josephs, K., Lowe, V.> ;Neuroimage. 2024 Feb 1
• Letter to the editor on: Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusi...
  Luo, H., Gustavsson, E., Macpherson, H., Dominik, N., Zhelcheska, K., Montgomery, K., Anderson, C., Yau, W., Efthymiou, S., Turner, C., DeTure, M., Dickson, D., Joseph...> ;Acta Neuropathologica Communications. 2024 Jan 2
• 1 citations
  Combined assessment of progressive apraxia of speech brain microstructure by diffusion tensor imaging tractography and multishell neurite orientation dispersion and de...
  Gatto, R., Meade, G., Duffy, J., Utianski, R., Machulda, M., Whitwell, J., Clark, H., Botha, H., Josephs, K.> ;Brain and Behavior. 2024 Jan 1
• Volumetric analysis of hippocampal subregions and subfields in left and right semantic dementia.
  Stephen D Weigand, Joseph R Duffy, Rene L Utianski, Mary M Machulda, Nha Trang Thu Pham, Christopher G Schwarz, Jennifer L Whitwell, Arenn F Carlos, Heather M Clark, H...> ;Brain Communications. 2024 Jan 1
• Longitudinal default mode sub-networks in the language and visual variants of Alzheimer's disease.
  Irene Sintini, Nick Corriveau-Lecavalier, David T Jones, Mary M Machulda, Jeffrey L Gunter, Christopher G Schwarz, Hugo Botha, Arenn F Carlos, Michael G Kamykowski, Ne...> ;Brain Communications. 2024 Jan 1
• Behavioral and Neuropsychiatric Differences Across Two Atypical Alzheimer's Disease Variants: Logopenic Progressive Aphasia and Posterior Cortical Atrophy.
  Robinson, C., Coleman, T., Singh, N., Pham, N., Machulda, M., Whitwell, J., Buciuc, M., Graff-Radford, J., Josephs, K.> ;Journal of Alzheimer's Disease. 2024 Jan 1
• The MAPT p.E342K and p.R406W mutations are associated with progressive supranuclear palsy with atypical features.
  Badihian, N., Machulda, M., Stierwalt, J., Pham, N., Baker, M., Rademakers, R., Whitwell, J., Ali, F., Botha, H., Savica, R., Clark, H., Lowe, V., Josephs, K.> ;Parkinsonism & Related Disorders. 2024 Feb 1
• Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old.
  Sekiya, H., Gatto, R., Casey, M., Pham, N., Sintini, I., Machulda, M., Whitwell, J., Petrucelli, L., Reichard, R., Dickson, D., Carlos, A., Koga, S., Jack, C., Lowe, V...> ;Journal of Neuropathology and Experimental Neurology. 2023 Dec 22
• Amyloid and Tau PET Positivity in Progressive Agrammatic Aphasia and Apraxia of Speech.
  Katerina A Tetzloff, Joseph R Duffy, Heather M Clark, Nha Trang Thu Pham, Mary M Machulda, Hugo Botha, Clifford R Jack, Dennis W Dickson, Val J Lowe, Keith A Josephs, ...> ;Journal of Alzheimer's Disease. 2023 Jan 1
• Diffusion tensor imaging-based multi-fiber tracking reconstructions can regionally differentiate phonetic versus prosodic subtypes of progressive apraxia of speech.
  Rodolfo G Gatto, Peter R Martin, Rene L Utianski, Joseph R Duffy, Heather M Clark, Hugo Botha, Mary M Machulda, Keith A Josephs, Jennifer L Whitwell> ;Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 2024 Feb 1
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Journal Articles

• Association of Apolipoprotein E ε4 with Transactive Response DNA-Binding Protein 43  
  Bradley F Boeve, Dennis W Dickson, David S Knopman, Joseph E Parisi, Ronald C Petersen, Keith A Josephs, JAMA
• Prosodic and Phonetic Subtypes of Primary Progressive Apraxia of Speech  
  Mary M. Machulda, Keith A. Josephs, Rene L. Utianski, Ronald C. Petersen, Edythe A. Strand, Val J. Lowe, ScienceDirect
• Corticobasal Degeneration with TDP-43 Pathology Presenting with Progressive Supranuclear Palsy Syndrome: A Distinct Clinicopathologic Subtype  
  J Eric Ahlskog, Keith A Josephs, Ryan J Uitti, Bradley F Boeve, Irene Litvan, Dennis W Dickson, Acta Neuropathologica
• Disrupted Functional Connectivity in Primary Progressive Apraxia of Speech  
  Mary M Machulda, Keith A Josephs, Rene L Utianski, Joseph R Duffy, David S Knopman, David T Jones, Ronald C Petersen, Edythe A Strand, ScienceDirect
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