KennethBerMarguliesMD
Cardiology • Philadelphia, PAHeart Failure & Transplantation, Cardiac Critical Care
Professor, Medicine, Perelman School of Medicine
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Office
(Lab) Smilow TRC, 3400 Civic Center Boulevard
Room 11-101
Philadelphia, PA 19104Phone+1 215-573-2980- Is this information wrong?
Education & Training
Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Cardiovascular Disease, 1989 - 1993- Mayo Clinic College of Medicine and Science (Rochester)Internship, Internal Medicine, 1986 - 1987
Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1986
Princeton UniversityAB, Summa Cum Laude, 1978 - 1982- Princeton UniversityAB, Summa Cum Laude, 1978 - 1982
Certifications & Licensure
FL State Medical License 2022 - Present
PA State Medical License 1993 - 2024
MN State Medical License 1987 - 1994- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2014
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
- Elected Member The American Society for Clinical Investigation, 2006
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Clinical Trials
- Study of Anginera in Adults With a Left Ventricular Assist Device (LVAD) as Bridge to Transplant Start of enrollment: 2006 Dec 01
- Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) Start of enrollment: 2013 Apr 01
- Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction Start of enrollment: 2014 Apr 01
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Publications & Presentations
PubMed
- Failing to Make the Grade: Conventional Cardiac Allograft Rejection Grading Criteria Are Inadequate for Predicting Rejection Severity.Sara Arabyarmohammadi, Cai Yuan, Vidya Sankar Viswanathan, Priti Lal, Michael D Feldman, Pingfu Fu, Kenneth B Margulies, Anant Madabhushi, Eliot G Peyster> ;Circulation. Heart Failure. 2024 Feb 1
- Distinct cytoskeletal regulators of mechanical memory in cardiac fibroblasts and cardiomyocytes.Nesrine Bouhrira, Alexia Vite, Kenneth B Margulies> ;Basic Research in Cardiology. 2024 Apr 1
- 1 citationsFunctional Impact of Alternative Metabolic Substrates in Failing Human Cardiomyocytes.Vite, A., Matsuura, T., Bedi, K., Flam, E., Arany, Z., Kelly, D., Margulies, K.> ;JACC. Basic to Translational Science. 2024 Jan 1
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Journal Articles
- Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients with Heart Failure with Preserved Ejection FractionGregory D Lewis, David J Whellan, Martin M LeWinter, Margaret M Redfield, Andrew L Smith, Eugene Braunwald, Michael M Givertz, Adrian F Hernandez, Sanjiv J Shah, Horng..., JAMA
- Suppression of Detyrosinated Microtubules Improves Cardiomyocyte Function in Human Heart FailureKenneth Margulies, MD, Nature
Abstracts/Posters
- A Novel Needleless Liquid Jet Injection System for Heart Failure Gene Therapy: Feasibility Study Demonstrates Enhanced Myocardial Distribution and Safety Profile in th...Fargnoli AS, Mu A, Katz MG, Williams RD, Dvorak J, Walling T, Margulies KB, Bridges CR, J Cardiac Fail, 1/1/2013
- A Novel Anti-Inflammatory Formulation Approach To Enhance Myocardial Gene Transfer: An In-Vitro Assessment of Aspirin Loaded Poly-Lactic Glycolic Acid NanoparticlesFargnoli AS, Mu A, Katz MG, Williams, Sumaroka, MV, Levy R,Weiner, DB, Diamond SL, Margulies KB, Yang S, Bridges, CR, Mol Therapy, 1/1/2013
- Patients with Obesity and Type-2 Diabetes Present Cardiac IAPP Accumulation: A Source of Cardiomyocyte Ca2+ DysregulationDespa S, Margulies KB, Bers D, Despa F, Circulation, 1/1/2011
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Lectures
- Takutsobo's Cardiomyopathy: Diagnosis and Recovery2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
- Generation of 3D Myocardial Tissue from Stem Cells11/17/2013
- Reverse Myocardial Remodeling Following LVAD: Where to We Stand?1/13/2013
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Press Mentions
Penn Medicine Cardiologist Is Honored with 2023 Edward S. Cooper, MD AwardJanuary 26th, 2023- Finally, a Cornerstone Drug for Heart Failure That Works Across the Entire EF Spectrum -News ForestAugust 28th, 2022
- Dapagliflozin ‘Foundational Therapy’ for HF, Regardless of EF: DELIVERAugust 27th, 2022
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Grant Support
- Mid Atlantic Heart Failure NetworkNational Heart, Lung, And Blood Institute2012
- Endogenous Cardiac Repair In HumansNational Heart, Lung, And Blood Institute2009–2012
- Integrative Genomics Of Human Heart FailureNational Heart, Lung, And Blood Institute2011
- Mechanisms Of Improved Diastolic Function In Human HeartNational Institute On Aging2004–2007
- Mechanisms Of Improved Diastolic Function In Human HeartNational Institute On Aging1998–2003
- Cardiac Myocyte Function Following Mechanical SupportNational Heart, Lung, And Blood Institute1997–2001
Hospital Affiliations
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania
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