LalithaVIyerMD

PubMed

• 23 citations
  Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.
  Francesca Curreli, Dmitry S. Belov, Young Do Kwon, Ranjith R. Ramesh, Anna M. Furimsky, Kathleen O’Loughlin, Patricia C. Byrge, Lalitha V. Iyer, Jon C. Mirsalis, Alexa...> ;European Journal of Medicinal Chemistry. 2018 Jun 25
• 14 citations
  In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO)
  Taylor A. Choi, Anna M. Furimsky, Robert Swezey, Deborah I. Bunin, Patricia C. Byrge, Lalitha V. Iyer, Polly Y. Chang, Rebecca J. Abergel> ;Journal of Pharmaceutical Sciences. 2015 May 1
• 2 citations
  Evaluation of Antitrypanosomal Dihydroquinolines for Hepatotoxicity, Mutagenicity, and Methemoglobin Formation In Vitro
  Karl A. Werbovetz, Edward S. Riccio, Anna M. Furimsky, Julian V. Richard, Shanshan He, Lalitha V. Iyer, Jon C. Mirsalis> ;International Journal of Toxicology. 2014 May 12
• 175 citations
  A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
  Peter B. Madrid, Sidharth Chopra, Ian D. Manger, Lynne Gilfillan, Tiffany R. Keepers, Amy C. Shurtleff, Carol E. Green, Lalitha V. Iyer, Holli Hutcheson Dilks, Robert ...> ;Plos One. 2013 Apr 5
• 8 citations
  Lead optimization of antimalarial propafenone analogues.
  David J. Lowes, Anupam Pradhan, Lalitha V. Iyer, Toufan Parman, Jason Gow, Fangyi Zhu, Anna M. Furimsky, Andrew Lemoff, W. Armand Guiguemde, Martina Sigal, Julie Clark...> ;Journal of Medicinal Chemistry. 2012 Jul 12
• 2 citations
  The stereoselective sulfate conjugation of 4'-methoxyfenoterol stereoisomers by sulfotransferase enzymes.
  Lalitha V. Iyer, Anuradha Ramamoorthy, Ewelina Rutkowska, Anna M. Furimsky, Liang Tang, Paul Catz, Carol E. Green, Krzysztof Jozwiak, Irving W. Wainer> ;Chirality. 2012 Jun 29
• 14 citations
  Discovery and optimization of benzotriazine di-N-oxides targeting replicating and nonreplicating Mycobacterium tuberculosis.
  Sidharth Chopra, Gary Koolpe, Arlyn Tambo-ong, Karen Matsuyama, Kenneth J. Ryan, Tran Tran, Rupa S. Doppalapudi, Edward S. Riccio, Lalitha V. Iyer, Carol E. Green, Bao...> ;Journal of Medicinal Chemistry. 2012 Jun 25
• 54 citations
  Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials.
  Yiqun Zhang, Julie Clark, Michele Connelly, Fangyi Zhu, Jaeki Min, W. Armand Guiguemde, Anupam Pradhan, Lalitha V. Iyer, Anna M. Furimsky, Jason Gow, Toufan Parman, Fa...> ;Journal of Medicinal Chemistry. 2012 May 10
• 74 citations
  A parallel chiral-achiral liquid chromatographic method for the determination of the stereoisomers of ketamine and ketamine metabolites in the plasma and urine of pati...
  Ruin Moaddel, Swarajya Lakshmi Vattem Venkata, Mary J. Tanga, James E. Bupp, Carol E. Green, Lalitha V. Iyer, Anna M. Furimsky, Michael E. Goldberg, Marc C. Torjman, I...> ;Talanta. 2010 Oct 15
• 39 citations
  Development of a New Generation of 4-Aminoquinoline Antimalarial Compounds Using Predictive Pharmacokinetic and Toxicology Models
  Sunetra Ray, Peter B. Madrid, Paul Catz, Susanna E. LeValley, Michael J. Furniss, Linda L. Rausch, R. Kiplin Guy, Joseph L. DeRisi, Lalitha V. Iyer, Carol E. Green, Jo...> ;Journal of Medicinal Chemistry. 2010 May 13
• 5 citations
  Pharmacokinetics and metabolism of (R,R)-methoxyfenoterol in rat
  Danuta Siluk, Donald E. Mager, Hee Seung Kim, Yan Wang, Anna M. Furimsky, Amy Ta, Lalitha V. Iyer, Carol E. Green, Irving W. Wainer> ;Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 2010 Feb 10
• 21 citations
  Effect of Resveratrol on 17β-Estradiol Sulfation by Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
  Anna M. Furimsky, Carol E. Green, Lewanne E. Hunt Sharp, Paul Catz, Araba A. Adjei, Toufan Parman, Izet M. Kapetanovic, Richard M. Weinshilboum, Lalitha V. Iyer> ;Drug Metabolism and Disposition. 2008 Jan 1
• 45 citations
  Endoscopic placement of the small-bowel video capsule by using a capsule endoscope delivery device.
  Jeremy P. Holden, Parul Dureja, Patrick R. Pfau, Darren C. Schwartz, Mark Reichelderfer, Robert H. Judd, Istvan Danko, Lalitha V. Iyer, Deepak V. Gopal> ;Gastrointestinal Endoscopy. 2007 May 1
• 52 citations
  Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms.
  Shirley S. Brill, Anna M. Furimsky, Mark Nguyen Ho, Michael J. Furniss, Yi Li, Adam G. Green, Carol E. Green, Lalitha V. Iyer, Wallace W. Bradford, Izet M. Kapetanovic> ;The Journal of Pharmacy and Pharmacology. 2010 Feb 18
• 34 citations
  Glucuronidation of 1'-hydroxyestragole (1'-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9.
  Lalitha V. Iyer, Mark Nguyen Ho, Walter Shinn, Wallace W. Bradford, Mary J. Tanga, Shirley S. Nath, Carol E. Green> ;Toxicological Sciences. 2003 May 1
• 35 citations
  In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes.
  Jacqueline Ramírez, Lalitha Iyer, Kim Journault, Patrick Bélanger, Federico Innocenti, Mark J. Ratain, Chantal Guillemette> ;Pharmaceutical Research. 2002 May 1
• 69 citations
  Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice.
  Lalitha Iyer, Jacqueline Ramírez, Dale R. Shepard, Christopher Bingham, Dieter Kurt Hossfeld, Mark J. Ratain, Ulrich Mayer> ;Cancer Chemotherapy and Pharmacology. 2002 Feb 1
• 111 citations
  Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7
  Federico Innocenti, Lalitha Iyer, Jacqueline Ramírez, Mitchell D. Green, Mark J. Ratain> ;Drug Metabolism and Disposition. 2001 May 1
• 69 citations
  Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.
  Federico Innocenti, Lalitha Iyer, Mark J. Ratain> ;Drug Metabolism and Disposition. 2001 Apr 1
• 64 citations
  Clinical pharmacology of camptothecins
  Lalitha Iyer, Mark J. Ratain> ;Cancer Chemotherapy and Pharmacology. 1998 Jan 1
• 24 citations
  Phase I clinical and pharmacokinetic study of oral 9-aminocamptothecin (NSC-603071)
  Sridhar Mani, Lalitha Iyer, Linda Janisch, Xiaolin Wang, Gini F. Fleming, Richard L. Schilsky, Mark J. Ratain> ;Cancer Chemotherapy and Pharmacology. 1998 Jan 1
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