
Lewis R Roberts MD PhD
Biliary Tract Disease, Gastrointestinal Cancer, Hepatology & Liver Transplantation
Liver and Biliary Neoplasia at Mayo Clinic Rochester
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200 1st St SWRochester, MN 55905
Phone+1 507-284-2511
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Summary
- I am a board certified Gastroenterologist and Hepatologist specializing in the diagnosis and treatment of liver and biliary tract malignancies and liver mass lesions. I completed my Internal Medicine and Gastroenterology training at Mayo Clinic, where I serve as Associate Director of the Predoctoral Masters Degree Program in Clinical and Translational Sciences. My research interests are in hepatobiliary malignancies, spanning the spectrum from basic research into the signaling pathways regulating the growth, progression and metastases of liver and biliary cancers, translational studies of new biomarkers and diagnostic tests for early diagnosis, and epidemiological studies of the risk factors and determinants of development of liver and biliary cancers. I am also actively involved in educational and health policy initiatives to improve the prevention, access to care, and treatment of liver cancer patients in the United States, particularly including immigrant African and Asian communities, as well as in sub-Saharan Africa.
Education & Training
Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Gastroenterology, 1995 - 1998
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1992 - 1995
The University of IowaPhD, Physiology and Biophysics, 1986 - 1992
University of Ghana Medical SchoolClass of 1982
Certifications & Licensure
MN State Medical License 1994 - 2027
WI State Medical License 1995 - 2027
IA State Medical License 1995 - 2008
American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification Centricity Enterprise (CE), GE Healthcare, 2014-2017
- CMS Meaningful Use Stage 2 Certification Mayo Clinic Incorporate Lab Results, Mayo Clinic, 2014-2017
- CMS Meaningful Use Stage 1 Certification Centricity Enterprise (CE), GE Healthcare, 2014-2017
Clinical Trials
- Hepatitis B Research Network Adult Cohort Study Start of enrollment: 2010 Dec 01
- HBRN: Immune Regulation and Costimulation in Natural History of Chronic Hepatitis B Start of enrollment: 2011 Feb 01
- Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer Start of enrollment: 2012 Mar 01
Publications & Presentations
PubMed
- Lower Allele Frequency of-rs2242652 in Sub-Saharan African Populations Compared With American Populations and Hepatocellular Carcinoma Risk.Perapa Chotiprasidhi, Viviana P Gonzalez Umpierre, Yvonne Ayerki Nartey, Hunter B Miller, Adrienne F Gefre
JCO Global Oncology. 2026-03-01 - Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits.Younghun Han, Vikram R Shaw, Jinyoung Byun, Aaron P Thrift, Catherine Zhu
International Journal of Cancer. 2026-03-01 - Circulating cell-free DNA methylation biomarkers for hepatocellular carcinoma risk prediction in HIV-positive Nigerian population.Yinan Zheng, Jingzhe Han, Yishu Qu, Jun Wang, Brian T Joyce
International Journal of Cancer. 2026-03-01
Journal Articles
- Clinical Features Associated with Survival Outcome in African-American Patients with Hepatocellular CarcinomaJennifer Leong, Lewis Roberts, Myron Schwartz, Mindie H Nguyen, Nature
Press Mentions
Blue Faery Gives Liver Cancer Research AwardApril 8th, 2022
The Blue Faery “Love Your Liver” Public Awareness CampaignFebruary 14th, 2022
‘Our Goal Is to Achieve a World Without Viral Hepatitis’October 1st, 2021
Grant Support
- Radiation and dendritic cell combination to improve immunotherapy response in intrahepatic cholangiocarcinomaMAYO CLINIC ROCHESTER2024–2029
- Mayo Clinic Hepatobiliary SPOREMAYO CLINIC ROCHESTER2018–2029
- Mayo Clinic Hepatobiliary SPOREMAYO CLINIC ROCHESTER2018–2029
- Africa HepatoPancreatoBiliary Cancer ConsortiumMAYO CLINIC ROCHESTER2025–2028
- International Consortium for the Genetics of Biliary Tract Cancers Cholangiocarcinoma Genome Wide Association StudyMAYO CLINIC ROCHESTER2023–2028
Professional Memberships
- Member
- Fellow
- Fellow
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