LloydMillerMD

PubMed

• 1 citations
  Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis.
  Jaewon You, Michael D Reilly, Mahmoud Eljalby, Rohan Bareja, Maftuna Yusupova, Nikki S Vyas, Jakyung Bang, Wanhong Ding, Garrett Desman, Lloyd S Miller, Olivier Elemen...> ;Experimental Dermatology. 2023 Jul 1
• 7 citations
  The Novel Oxazolidinone TBI-223 Is Effective in Three Preclinical Mouse Models of Methicillin-Resistant Staphylococcus aureus Infection.
  Oren Gordon, Dustin A Dikeman, Roger V Ortines, Yu Wang, Christine Youn, Mohammed Mumtaz, Nicholas Orlando, Jeffrey Zhang, Aman M Patel, Ethan Gough, Amit Kaushik, Eri...> ;Microbiology Spectrum. 2022 Oct 26
• 15 citations
  Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.
  Xintong Dong, Nathachit Limjunyawong, Elizabeth I Sypek, Gaofeng Wang, Roger V Ortines, Christine Youn, Martin P Alphonse, Dustin Dikeman, Yu Wang, Mark Lay, Ruchita K...> ;Immunity. 2022 Sep 13
• 9 citations
  Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant-associated infections.
  Oren Gordon, Donald E. Lee, Bessie Liu, Brooke Langevin, Alvaro A. Ordonez, Dustin Dikeman, Babar Shafiq, John M. Thompson, Paul D. Sponseller, Kelly Flavahan, Martin ...> ;Science Translational Medicine. 2021 Dec 1
• 24 citations
  Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis.
  Garrett J. Patrick, Nathan K. Archer, Lloyd S. Miller> ;The Journal of Investigative Dermatology. 2021 Feb 1
• 13 citations
  Research Techniques Made Simple: Mouse Bacterial Skin Infection Models for Immunity Research.
  Christine Youn, Nathan K. Archer, Lloyd S. Miller> ;The Journal of Investigative Dermatology. 2020 May 11
• 14 citations
  Interleukin-1β and tumor necrosis factor are essential in controlling an experimental orthopedic implant-associated infection.
  Yu Wang, Alyssa G. Ashbaugh, Dustin Dikeman, Jeffrey Zhang, Nicole E. Ackerman, Sophie E. Kim, Christian Falgons, Roger V. Ortines, Haiyun Liu, Daniel P. Joyce, Martin...> ;Journal of Orthopaedic Research. 2020 Jan 24
• 106 citations
  Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
  Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hub...> ;Nature Communications. 2020 Jan 8
• 6 citations
  Preclinical Models and Methodologies for Monitoring Staphylococcus aureus Infections Using Noninvasive Optical Imaging.
  Nathan K. Archer, Yu Wang, Roger V. Ortines, Haiyun Liu, Sabrina J. Nolan, Qi Liu, Martin P. Alphonse, Dustin Dikeman, Momina Mazhar, Robert J. Miller, Leif S. Anderso...> ;Methods in Molecular Biology. 2020 Jan 1
• 132 citations
  Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms.
  Lloyd S. Miller, Vance G. Fowler, Sanjay K. Shukla, Warren E. Rose, Richard A. Proctor> ;FEMS Microbiology Reviews. 2020 Jan 1
• 23 citations
  Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections
  Robert J. Miller, Heidi A. Crosby, Katrin Schilcher, Yu Wang, Roger V. Ortines, Momina Mazhar, Dustin Dikeman, Bret L. Pinsker, Isabelle D. Brown, Daniel P. Joyce, Jef...> ;Scientific Reports. 2019 Nov 13
• 33 citations
  Association between prurigo nodularis and malignancy in middle-aged adults
  Olive Tang, Sonja Ständer, Lloyd S. Miller, Sewon Kang, Shawn G. Kwatra> ;Journal of the American Academy of Dermatology. 2019 Apr 5
• 85 citations
  Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.
  Angel S. Byrd, Carmelo Carmona-Rivera, Liam J. O’Neil, Philip M. Carlucci, Cecilia Cisar, Avi Z. Rosenberg, Michelle L. Kerns, Julie Caffrey, Stephen M. Milner, Justin...> ;Science Translational Medicine. 2019 Sep 4
• 27 citations
  Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.
  Franziska Herster, Zsofia Bittner, Marius Cosmin Codrea, Nathan K. Archer, Martin Heister, Markus W. Löffler, Simon Heumos, Joanna Wegner, Ramona Businger, Michael Sch...> ;Frontiers in Immunology. 2019 Aug 16
• 3 citations
  Author Correction: Comparison of livestock-associated and community-associated Staphylococcus aureus pathogenicity in a mouse model of skin and soft tissue infection.
  Pranay R. Randad, Carly A. Dillen, Roger V. Ortines, David W. Mohr, Maliha Aziz, Lance B. Price, Hülya Kaya, Jesper Larsen, Karen C. Carroll, Tara C. Smith, Lloyd S. M...> ;Scientific Reports. 2019 Sep 2
• 18 citations
  Disseminated sporotrichosis following iatrogenic immunosuppression for suspected pyoderma gangrenosum
  Marissa J. White, La'Tonzia T. Adams, Casey Phan, Gulsun Erdag, Marissa Totten, Richard T. Lee, Xuelian Lu, Seema Mehta, Lloyd S. Miller, Sean X. Zhang> ;The Lancet. Infectious Diseases. 2019 Nov 1
• 9 citations
  Theranostic biocomposite scaffold membrane.
  Emmanuel Roussakis, Roger V. Ortines, Bret L. Pinsker, Cavin T. Mooers, Conor L. Evans, Lloyd S. Miller, Xiomara Calderon-Colon> ;Biomaterials. 2019 Aug 1
• 8 citations
  Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice.
  Roger V. Ortines, Yu Wang, Haiyun Liu, Dustin Dikeman, Bret L. Pinsker, Robert J. Miller, Sophia E. Kim, Nicole E. Ackerman, Joe F. Rizkallah, Lee Ann T. Marcello, Tay...> ;Antimicrobial Agents and Chemotherapy. 2019 Jul 25
• 52 citations
  Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3
  Dongwon Kim, Ruosi Chen, Mary Sheu, Noori Kim, S. Kim, Nasif Islam, Eric M. Wier, Gaofeng Wang, Ang Li, Angela Park, Wooyang Son, Benjamin R. Evans, Victoria Yu, Vicky...> ;Nature Communications. 2019 Jun 26
• 5 citations
  Association of particulate matter air pollution and itch: A digital epidemiology approach.
  Katherine A. Whang, Amy H. Huang, Lloyd S. Miller, Sewon Kang, Shawn G. Kwatra> ;Journal of the American Academy of Dermatology. 2019 May 11
• 8 citations
  Comparison of livestock-associated and community-associated Staphylococcus aureus pathogenicity in a mouse model of skin and soft tissue infection
  Pranay R. Randad, Carly A. Dillen, Roger V. Ortines, David W. Mohr, Maliha Aziz, Lance B. Price, Hülya Kaya, Jesper Larsen, Karen C. Carroll, Tara C. Smith, Lloyd S. M...> ;Scientific Reports. 2019 May 1
• 7 citations
  CCR6+ γδ T Cells Home to Skin Wounds and Restore Normal Wound Healing in CCR6-Deficient Mice.
  Leif S. Anderson, Sebastian Yu, Kathryn R. Rivara, Mack B. Reynolds, Alfredo A Hernandez, Xuesong Wu, Hsin Ya Yang, Roslyn Rivkah Isseroff, Lloyd S. Miller, Samuel T H...> ;The Journal of Investigative Dermatology. 2019 Sep 1
• 49 citations
  Injury, dysbiosis, and filaggrin deficiency drive skin inflammation through keratinocyte IL-1α release
  Ravipati, A., Nathan K. Archer, Jay-Hyun Jo, S. Lee, Dongwon Kim, Barbara S. Smith, Roger V. Ortines, Yu Wang, Mark C. Marchitto, Advaitaa Ravipati, Shuting S. Cai, Ca...> ;The Journal of Allergy and Clinical Immunology. 2019 Apr 1
• 25 citations
  Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone.
  Julie E. Pickett, John M. Thompson, Agnieszka Sadowska, Christine Tkaczyk, Bret R. Sellman, Andrea Minola, Davide Corti, Antonio Lanzavecchia, Lloyd S. Miller, Daniel ...> ;Bone Research. 2018 Apr 25
• 4 citations
  Neutrophils in hot pursuit of MRSA in the lymph nodes
  Lloyd S. Miller, Scott I. Simon> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Mar 6
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Journal Articles

• Combination Prophylactic Therapy with Rifampin has Increased Efficacy Against an Experimental Staphylococcus epidermidis Subcutaneous Implant-Related Infection  
  Stavrakis, AI, Niska, JA, Shahbazian, JH, Loftin, AH, Ramos, RI, Billi, F, Francis, KP, Otto, M, Bernthal, NM, Uslan, DZ, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2014
• Combined in Vivo Optical and MuCT Imaging to Monitor Infection, Inflammation and Bone Anatomy in an Orthopaedic Implant Infection in Mice  
  Bernthal, NM, Taylor, BN, Meganck, JA, Wang, Y, Shahbazian, JH, Niska, JA, Francis, KP, Miller, LS, Journal of Visualized Experiments, 1/1/2014
• In Vivo Bioluminescence Imaging to Evaluate Systemic and Topical Antibiotics against Community-acquired Methicillin-resistant Staphylococcus Aureus-infected Skin Wound...  
  Guo, Y, Ramos, RI, Cho, JS, Donegan, NP, Cheung, AL, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2013
• Staphylococcus Aureus Recognition by Hematopoietic Stem and Progenitor Cells via TLR2/MyD88/PGE2 Stimulates Granulopoiesis in Wounds  
  Granick, JL, Falahee, P, Dahmubed, D, Borjesson, Miller, LS, Simon, SI, Blood, 1/1/2013
• Vancomycin-Rifampin Combination Therapy Has Enhanced Efficacy against an Experimental Staphylococcus aureus Prosthetic Joint Infection  
  Niska, JA, Shahbazian, JH, Ramos, RI, Francis, KP, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2013
• Mouse Model of Chronic Post-arthroplasty Infection: Noninvasive in Vivo Bioluminescence Imaging to Monitor Bacterial Burden for Long-term Study  
  Pribaz, JR, Bernthal, NM, Billi, F, Cho, JS, Ramos, RI, Francis, KP, Miller, LS, Journal of Orthopaedic Research, 1/1/2012
• Coordinate Regulation of Neutrophil Homeostasis by Liver X Receptors in Mice  
  Hong, C, Kidani, Y, A-Gonzalez, N, Phung, T, Ito, A, Rong, X, Ericson, K, Mikkola, H, Beaven, SW, Miller, LS, Shao, WH, Cohen, PL, Castrillo, A, Tontonoz, P, Bensinger..., Journal of Clinical Investigation, 1/1/2012
• Daptomycin and Tigecycline Have a Broader Effective Dose Range than Vancomycin as Prophylaxis against a Surgical Implant Staphylococcus Aureus Infection in Mice  
  Niska, JA, Shahbazian, JH, Ramos, RI, Pribaz, JR, Billi, F, Francis, KP, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2012
• Cutting Edge: Nitrogen Bisphosphonate-induced Inflammation Is Dependent upon Mast Cells and IL-1  
  Norton, JT, Hayashi, T, Crain, B, Cho, JS, Miller, LS, Corr, M, Carson, DA, Journal of Immunology, 1/1/2012
• Monitoring Bacterial Burden, Inflammation and Bone Damage Longitudinally Using Optical and MuCT Imaging in an Orthopaedic Implant Infection in Mice  
  Niska, JA, Meganck, JA, Pribaz, JR, Shahbazian, JH, Lim, E, Zhang, N, Rice, BW, Ramos, RI, Bernthal, NM, Francis, KP, Miller, LS, PLOS ONE, 1/1/2012
• LTB4 Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation  
  Oyoshi, MK, He,R, Li, Y, Mondal, S, Yoon, J, Afshar, R,  Chen, M, Lee, DM, Luo, HR, Luster, AD, Cho, JS, Miller, LS, Larson, Murphy, GF, Geha, RS, Immunity, 1/1/2012
• Neutrophil-derived IL-1beta Is Sufficient for Abscess Formation in Immunity against Staphylococcus Aureus in Mice  
  Cho, JS, Guo, Y, Ramos, RI, Hebroni, F, Plaisier, SB, Xuan, C, Granick, JL, Matsushima, H, Takashima, A, Iwakura, Y, Cheung, AL, Cheng, G, Lee, DJ, Simon, SI, Miller, LS, PLOS Pathogens, 1/1/2012
• Noninvasive in Vivo Imaging to Evaluate Immune Responses and Antimicrobial Therapy against Staphylococcus Aureus and USA300 MRSA Skin Infections  
  Cho, JS, Zussman, J, Donegan, NP, Ramos, RI, Garcia, NC, Uslan, DZ, Iwakura, Y, Simon, SI, Cheung, AL, Modlin, RL, Kim, J, Miller, LS, Journal of Investigative Dermatology, 1/1/2011
• Neutrophil Survival and C-kit+ Progenitor Proliferation in Staphylococcus Aureus Infected Skin Wounds Promote Resolution  
  Kim, M-H, Granick, JL, Kwok, C, Walker, N, Borjesson, DL, Curry, FE, Miller, LS, Simon, SI, Blood, 1/1/2011
• MyD88-dependent Activation of an IFNgammaR-CCR2 Signaling Circuit Is Required for Mobilization of Monocytes and Host Defense against Systemic Bacterial Challenge  
  Pietras, EM, Miller, LS, Johnson, CT, O'Connell, RM, Dempsey, PW, Cheng, G, Cell Research, 1/1/2011
• Protective Role of IL-1beta against Post-arthroplasty Staphylococcus Aureus Infection  
  Bernthal, NM, Pribaz, JR, Stavrakis, AI, Billi, F, Cho, JS, Ramos, RI, Francis, KP, Iwakura, Y, Miller, LS, Journal of Orthopaedic Research, 1/1/2011
• IL-23 and IL-17A, but Not IL-12 and IL-22, Are Required for Optimal Skin Host Defense against Candida Albicans  
  Kagami, S, Rizzo, HL, Kurtz, SE, Miller, LS, Blauvelt, A, Journal of Immunology, 1/1/2010
• IL-17 Is Essential for Host Defense against Cutaneous Staphylococcus Aureus Infection in Mice  
  Cho, JS, Pietras, EM, Garcia, NC, Ramos, RI, Farzam, DM, Monroe, HR, Magorien, JE, Blauvelt, A, Kolls, JK, Cheung, AL, Cheng, G, Modlin, RL, Miller, LS, Journal of Clinical Investigation, 1/1/2010
• A Novel Mouse Model of Post-arthroplasty Joint Infection to Evaluate in Vivo the Efficacy of Antimicrobial Implant Coatings  
  Bernthal, NM, Stavrakis, AI, Billi, F, Cho, JS, Kremen, TJ, Simon, SI, Cheung, AL, Finerman, G, Lieberman, JR, Adams, JS,  Miller, LS, PLOS ONE, 1/1/2010
• Downstream Signals for MyD88-Mediated Phagocytosis of Borrelia burgdorferi Can Be Initiated by TRIF and Are Dependent on PI3K  
  Shin, OS, Miller, LS, Modlin, RL, Akira, S, Uematsu, S, Hu, LT, Journal of Immunology, 1/1/2009
• A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome  
  Munoz-Planillo, R, Franchi , L, Miller, LS, Foster, T, Nunez, G, Journal of Immunology, 1/1/2009
• Dynamics of Neutrophil Infiltration during Cutaneous Wound Healing and Infection Using Fluorescence Imaging  
  Kim, Min-Ho, Liu, W, Borjesson, DL, Curry, FE, Miller, LS, Cheung, AL, Liu, F-T, Isseroff, RR, Simon, SI, Journal of Investigative Dermatology, 1/1/2008
• Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model  
  Maren von Kockritz-Blickwede, M, Rohde, M, Oehmcke, S, Miller, LS, Cheung, AL, Herwald, H, Foster, S, Medina, E, American Journal of Pathology, 1/1/2008
• Increased Expression of CD23 (Fc Epsilon Receptor II) By Peripheral Blood Monocytes of AIDS Patients  
  Miller, LS, Atabai, K, Nowakowski, M, Chan, A, Bluth, M, Minkoff, H, Durkin, HG, AIDS Research and Human Retroviruses, 1/1/2001
• Suppression of Cytokine-induced Neutrophil Accumulation in Rat Mesenteric Venules in Vivo by General Anesthesia  
  Miller, LS, Morita, Y, Rangan, U, Kondo, S, Clemens, MG, Bulkley, GB, International Journal of Microcirculation, Clinical and Experimental, 1/1/1996
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Books/Book Chapters

• Fitzpatrick's Dermatology in General Medicine 
  Chapter: Innate and Adaptive Immunity in the Skin 
  Page 105 - 125Modlin, RL, Miller, LS, Bangert, C, Stingl, GMcGraw-HillEdition 8th,2012
• Clinical and Basic Immunodermatology 
  Chapter: Bacterial Infections 
  Page 335 - 363Senavsky, C, Craft, N, Miller, LSEditors: Gaspari, AA, Tyring, SK.Springer (London), Guildford, United Kingdom2008

Lectures

• Structure and Function of the Skin: Cancer, Immunity and Inflammation 
  American Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/1/2019
• Noninvasive in Vivo Optical and Anatomical Imaging in Mice Provides Novel Insights into the Pathogenesis, Treatment and Diagnosis of S. Aureus Infections 
  Division of Bacterial, Parasitic, and Allergenic Products, Silver Spring, MD - 11/1/2014
• Noninvasive Monitoring of Bacteria Burden, Inflammation and Efficacy of Antimicrobial Therapy in Infected Wounds in Mice Using Optical Imaging 
  Washington, D.C. - 9/1/2014
•  
  Seoul, Korea - 9/1/2014
• Novel Bioengineered Antimicrobial Surgical Implant Coatings to Prevent Prosthetic Joint Infections 
  Johns Hopkins University School of Medicine, Baltimore, MD - 7/1/2014
• Recent Insights into Immunity against Staphylococcus Aureus Skin Infections 
  University of Minnesota, Minneapolis, MN - 2/1/2014
• Mechanisms of Immune Protection of Multifunctional Monoclonal Antibodies against Staphylococcus Aureus Infections 
  Gaithersburg, MD - 2/1/2014
• Mouse Models of Staphylococcus Aureus Infections to Study Pathogenesis, Immune Responses and Antimicrobial Therapy 
  Division of Infectious Diseases, Johns Hopkins, Baltimore, MD - 11/1/2013
• Optical Imaging for Bacterial Infections: Skin, Joint and Bone 
  Johns Hopkins, Baltimore, MD - 9/1/2013
• Innate Immune Mechanisms That Promote Neutrophil Recruitment against Cutaneous Staphylococcus Aureus Infection 
  Waterville Valley, NH - 7/1/2013
• Differential Cell Intrinsic MyD88- and STAT3-signaling Promote Immunity against Staphylococcus Aureus Skin Infection 
  Edinburgh, Scotland - 5/1/2013
• Mechanisms that Promote Neutrophil Recruitment against Staphylococcus aureus Skin Infections 
  Washington, DC - 2/1/2013
• Skin: Maginot Line or Early Warning System? 
  Washington, DC - 2/1/2013
• Mouse Models of Staphylococcus Aureus Infections to Study Immune Responses - What Have We Learned? 
  Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD - 12/1/2012
• IL-1 and IL-17 Responses in Immunity against Staphylococcus Aureus Skin Infections 
  Johns Hopkins University School of Medicine Baltimore, MD - 12/1/2012
• IL-1 and IL-17 Responses in Immunity against Staphylococcus Aureus Skin Infections, Grand Rounds 
  Division of Dermatology, University of Washington, Seattle, WA - 7/1/2012
• Host-pathogen Interactions Involving the Skin and Staphylococcus Aureus (Review Article) 
  1/1/2012
• The Innate and Adaptive Immune Response against Staphylococcus Aureus Skin Infections (Review Article) 
  1/1/2012
• Noninvasive Real-time Imaging to Study Orthopaedic Implant Infections in a Mouse Model 
  Department of Orthopaedic Surgery, Johns Hopkins, Baltimore, MD - 1/1/2012
• Combined In Vivo Bioluminescence, Fluorescence, X-ray and MuCT Imaging to Study Bacterial Infection, Biofilm Formation and Host-Pathogen Interactions 
  San Diego, CA - 9/1/2011
• Triggering Neutrophil Recruitment against Staphylococcus Aureus Skin Infections, Grand Rounds 
  Department of Dermatology, Johns Hopkins, Baltimore, MD - 7/1/2011
• Mechanisms of Innate Immunity against Staphylococcus Aureus Skin Infection 
  Department of Dermatology, Indiana University, Indianapolis, IN - 2/1/2011
• Immunity against Staphylococcus Aureus Cutaneous Infections (Review Article) 
  1/1/2011
• Protective Role of IL-1beta against Post-arthroplasty Staphylococcus Aureus Infection 
  Long Beach, CA - 1/1/2011
• Mouse Models of Staphylococcus aureus Skin Infection and What We Have Learned 
  Vancouver, Canada - 10/1/2010
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