MahaRedaFarhatMD

PubMed

• Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
  Jacob E. Lemieux, Katherine J. Siddle, Bennett M. Shaw, Christine Loreth, Stephen F. Schaffner, Adrianne Gladden-Young, Gordon Adams, Timelia Fink, Christopher Tomkins...> ;Science. 2020 Dec 10
• Mentorship at a distance
  Naomi A. Rankin, Matthias I. Gröschel, Maha R. Farhat> ;Science. 2020 Oct 23
• 6 citations
  Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19
  Mohamad El Moheb, Leon Naar, Mathias A. Christensen, Carolijn Kapoen, Lydia R. Maurer, Maha R. Farhat, Haytham M.A. Kaafarani> ;JAMA. 2020 Sep 24
• Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and...
  Suha Kadura, Nicholas King, Maria Nakhoul, Hongya Zhu, Grant Theron, Claudio U. Köser, Maha R. Farhat> ;Journal of Antimicrobial Chemotherapy. 2020 Aug 1
• The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia.
  Gröschel, M. I., Meehan, C. J., Barilar, I., Diricks, M., Gonzaga, A., Steglich, M., Conchillo-Solé, O., Scherer, I., Mamat, U., Luz, C. F., De Bruyne, K., Utpatel, C....> ;Nature communications. 2020 Apr 29
• Identification of a new genetic variant associated with cholecystitis: A multicenter genome-wide association study.
  Alexander Bonde, Apostolos Gaitanidis, Kerry Breen, Majed El Hechi, Charlie J. Nederpelt, Mathias A. Christensen, Nikolaos Kokoroskos, April E. Mendoza, George C. Velm...> ;Journal of Trauma-injury Infection and Critical Care. 2020 Feb 28
• Antibiotic treatment and selection for <i>glpK</i> mutations in patients with active tuberculosis disease.
  Vargas, R., Farhat, M. R.> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Feb 23
• Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
  Martin Hunt, Phelim Bradley, Simon Grandjean Lapierre, Simon Heys, Mark Thomsit, Michael B Hall, Kerri M. Malone, Penelope Wintringer, Timothy M Walker, Daniela M. Cir...> ;Wellcome open research. 2019 Dec 2
• DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.
  Yang Yang, Timothy M Walker, A S Walker, Daniel J. Wilson, Peto Tea., Derrick W. Crook, Farah Shamout, I Arandjelovic, I Comas, Maha R. Farhat, Q Gao, V Sintchenko, D....> ;Bioinformatics. 2019 Sep 15
• Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.
  Meehan, C. J., Goig, G. A., Kohl, T. A., Verboven, L., Dippenaar, A., Ezewudo, M., Farhat, M. R., Guthrie, J. L., Laukens, K., Miotto, P., Ofori-Anyinam, B., Dreyer, V...> ;Nature reviews. Microbiology. 2019 Jun 19
• Rifampicin and rifabutin resistance in 1003 Mycobacterium tuberculosis clinical isolates.
  Maha R. Farhat, Jaimie D. Sixsmith, Roger Calderon, Nathan D. Hicks, Sarah M. Fortune, Megan Murray> ;Journal of Antimicrobial Chemotherapy. 2019 Jun 1
• GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions.
  Maha R. Farhat, Luca Freschi, Roger Calderon, Thomas R. Ioerger, Matthew W. Snyder, Conor J. Meehan, Bouke C. de Jong, Leen Rigouts, Alexander Sloutsky, Devinder Kaur,...> ;Nature Communications. 2019 May 13
• Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction
  Michael L. Chen, Akshith Doddi, Jimmy Royer, Luca Freschi, Marco Schito, Matthew Ezewudo, Isaac S. Kohane, Andrew L. Beam, Maha R. Farhat> ;EBioMedicine. 2019 May 1
• Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting
  Avika Dixit, Luca Freschi, Roger Vargas, Roger Calderon, James C. Sacchettini, Francis Drobniewski, Jerome T Galea, Carmen Contreras, Rosa Yataco, Zibiao Zhang, Leonid...> ;Scientific Reports. 2019 Apr 3
• Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings.
  Benjamin Schubert, Rohan Maddamsetti, Jackson Nyman, Maha R. Farhat, Debora S. Marks> ;Nature microbiology. 2019 Feb 1
• Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.
  Caroline Allix-Béguec, Irena Arandjelovic, Lijun Bi, Patrick Beckert, Maryline Bonnet, Phelim Bradley, Andrea M. Cabibbe, Irving Cancino-Muñoz, Mark J. Caulfield, Angk...> ;The New England Journal of Medicine. 2018 Oct 11
• Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis
  Nira R. Pollock, Rakesh Dhiman, Nada Daifalla, Maha R. Farhat, Antonio Campos-Neto> ;Microbes and Infection. 2018 Apr 1
• Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome...
  Maha R. Farhat, Karen R. Jacobson, Molly F. Franke, Devinder Kaur, Megan Murray, Carole D. Mitnick> ;Clinical Infectious Diseases. 2017 Oct 15
• Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.
  Hanna Nebenzahl-Guimaraes, Arjan van Laarhoven, Maha R. Farhat, Valerie A C M Koeken, Jornt J. Mandemakers, Aldert Zomer, Sacha A. F. T. van Hijum, Mihai G. Netea, Meg...> ;American Journal of Respiratory and Critical Care Medicine. 2017 Jun 1
• Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.
  Maha R. Farhat, Razvan Sultana, Oleg Iartchouk, Sam Bozeman, James E. Galagan, Peter Sisk, Christian Stolte, Hanna Nebenzahl-Guimaraes, Karen R. Jacobson, Alexander Sl...> ;American Journal of Respiratory and Critical Care Medicine. 2016 Sep 1
• 5 citations
  Connectivity of diagnostic technologies: improving surveillance and accelerating tuberculosis elimination.
  Emmanuel André, Chris Isaacs, D. Affolabi, R Alagna, D Brockmann, B. C. de Jong, E Cambau, Gavin J. Churchyard, Ted Cohen, Michel Delmée, Jean-Charles Delvenne, Maha R...> ;International Journal of Tuberculosis and Lung Disease. 2016 Aug 1
• The nature, patterns, clinical outcomes, and financial impact of intraoperative adverse events in emergency surgery.
  Elie P. Ramly, Jordan D. Bohnen, Maha R. Farhat, Shadi Razmdjou, Michael N. Mavros, D. Dante Yeh, Jarone Lee, Kathryn L. Butler, Marc de Moya, George C. Velmahos, Hayt...> ;American Journal of Surgery. 2016 Jul 1
• Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis.
  Maha R. Farhat, Karen R. Jacobson, Molly F. Franke, Devinder Kaur, Alexander Sloutsky, Carole D. Mitnick, Megan Murray> ;Journal of Clinical Microbiology. 2016 Mar 1
• Concordance of Mycobacterium tuberculosis fluoroquinolone resistance testing: implications for treatment.
  Maha R. Farhat, Carole D. Mitnick, Molly F. Franke, Devinder Kaur, Alexander Sloutsky, Megan Murray, Karen R. Jacobson> ;International Journal of Tuberculosis and Lung Disease. 2015 Mar 1
• A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens
  Maha R. Farhat, B. Jesse Shapiro, Samuel K. Sheppard, Caroline Colijn, Megan Murray> ;Genome Medicine. 2014 Nov 15
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Journal Articles

• Gastrointestinal Complications in Critically Ill Patients with and Without COVID-19  
  Maha Farhat, MD, JAMA