MariaCatherinePietanzaMD

Oncology • New York, NY

Assistant Professor, Medicine, Weill Cornell Medical College

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Office
1275 York Ave
New York, NY 10021
Phone+1 212-639-2000
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Education & Training

Icahn School of Medicine at Mount SinaiFellowship, Hematology and Medical Oncology, 2004 - 2007
New York Presbyterian Hospital (Cornell Campus)Residency, Internal Medicine, 2001 - 2004
State University of New York Downstate Medical Center College of MedicineClass of 2001

Certifications & Licensure

NY State Medical License 2004 - 2025

Awards, Honors, & Recognition

Top Doctors: New York Metro Area Castle Connolly, 2014

Clinical Trials

Temozolomide for Relapsed Sensitive or Refractory Small Cell Lung Cancer Start of enrollment: 2008 Aug 01
Completed
Phase 2
Paclitaxel, Bevacizumab and Pemetrexed in Patients With Untreated, Advanced Non-Small Cell Lung Cancer Using Web-Based Data Collection, Patient Self-Reporting of Adverse Effects and Automated Response Assessment Start of enrollment: 2008 Dec 01
Completed
Phase 2
Immunization With a Pentavalent Vaccine Composed of KLH-conjugates of GD2L, GD3L, Globo H, Fucosyl GM1, and N-Propionylated Polysialic Acid Start of enrollment: 2011 May 01
Completed
Phase 1
Combination of the Hedgehog Inhibitor, LDE225, With Etoposide and Cisplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Start of enrollment: 2012 Apr 01
Completed
Phase 1
Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer Start of enrollment: 2012 Jun 01
Completed
Phase 2
A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum Therapy Start of enrollment: 2012 Jan 07
Terminated
Phase 1, Phase 2
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Publications & Presentations

PubMed

185 citations
Pemetrexed plus platinum with or without pembrolizumab in patients with previously untreated metastatic nonsquamous NSCLC: protocol-specified final analysis from KEYNO...
Delvys Rodriguez-Abreu, Steven Francis Powell, Maximilian Hochmair, Shirish M. Gadgeel, Emilio Esteban, Enriqueta Felip, G. Speranza, F. De Angelis, Manuel Domine, S. ...> ;Annals of Oncology. 2021 Jul 1
47 citations
Stage IV lung carcinoids: spectrum and evolution of proliferation rate, focusing on variants with elevated proliferation indices.
Natasha Rekhtman, Patrice Desmeules, Anna Maria Litvak, M.C. Pietanza, Maria Lauren Santos-Zabala, Ai Ni, Joseph Montecalvo, Jason C. Chang, Amanda Beras, Isabel Ruth ...> ;Modern Pathology. 2019 Mar 28
3 citations
Reply to F. Liang
M. Catherine Pietanza, Lixia Diao, Jing Wang, Lauren Averett Byers> ;Journal of Clinical Oncology. 2019 Jan 8
234 citations
Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell L...
M. Catherine Pietanza, Saiama N. Waqar, Lee M. Krug, Afshin Dowlati, Christine L. Hann, Alberto Chiappori, Taofeek K. Owonikoko, Kaitlin M. Woo, Robert J. Cardnell, Ju...> ;Journal of Clinical Oncology. 2018 Jun 15
4 citations
No Decision Is Final: Career Planning and Career Transitions
Brian Boulmay, Tatiana M. Prowell, Marcelo Blaya, Maria Catherine Pietanza> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2018 May 23
Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
Shirish Gadgeel, M Catherine Pietanza, Edward B Garon, Jhanelle E Gray, Leena Gandhi> ;The New England Journal of Medicine.
31 citations
Patterns of failure in limited-stage small cell lung cancer: Implications of TNM stage for prophylactic cranial irradiation.
Abraham J. Wu, Andrea Gillis, A. Foster, Kaitlin M. Woo, Zhigang Zhang, Daphna Y. Gelblum, Robert J. Downey, Kenneth E. Rosenzweig, Leonard Ong, C.A. Perez, M. Catheri...> ;Radiotherapy and Oncology. 2017 Oct 1
119 citations
Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy.
Akane Inoue-Yamauchi, Paul S Jeng, Kwanghee Kim, Hui Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria Catherine Pietanza,...> ;Nature Communications. 2017 Jul 17
333 citations
Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study
Charles M. Rudin, M. Catherine Pietanza, Todd M. Bauer, Neal Ready, Daniel Morgensztern, Bonnie S. Glisson, Lauren Averett Byers, Melissa Lynne Johnson, Howard A. Burr...> ;The Lancet. Oncology. 2017 Jan 1
9 citations
ORAL02.01: Safety and Efficacy of Single-Agent Rovalpituzumab Tesirine, a DLL3-Targeted ADC, in Recurrent or Refractory SCLC: Topic: Medical Oncology.
Todd M. Bauer, David R. Spigel, Neal Ready, Daniel Morgensztern, Bonnie S. Glisson, Lauren Averett Byers, Howard A. Burris, Francisco Robert, Donald K Strickland, Mari...> ;Journal of Thoracic Oncology. 2016 Nov 1
53 citations
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung...
M. Catherine Pietanza, Anya Litvak, Anna M. Varghese, Lee M. Krug, Martin Fleisher, Jerrold B. Teitcher, Andrei I. Holodny, C.S. Sima, Kaitlin M. Woo, Kenneth K.-S. Ng...> ;Lung Cancer. 2016 Sep 1
96 citations
Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes
Jarushka Naidoo, Maria Laureana Santos-Zabala, Tunc Iyriboz, Kaitlin M. Woo, Camelia S. Sima, John J. Fiore, Mark G. Kris, Gregory J. Riely, Piro Lito, Afsheen Iqbal, ...> ;Clinical Lung Cancer. 2016 Sep 1
342 citations
Phase III Randomized Trial of Ipilimumab Plus Etoposide and Platinum Versus Placebo Plus Etoposide and Platinum in Extensive-Stage Small-Cell Lung Cancer.
Martin Reck, Alexander Luft, Aleksandra Szczesna, Libor Havel, Sang We Kim, Wallace Akerley, Maria Catherine Pietanza, Yi-Long Wu, Christoph C. Zielinski, Michael Thom...> ;Journal of Clinical Oncology. 2016 Jul 25
273 citations
Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets
Natasha Rekhtman, Maria Catherine Pietanza, Matthew D. Hellmann, Jarushka Naidoo, Arshi Arora, Helen Won, Darragh Halpenny, Hangjun Wang, Shaozhou K. Tian, Anya Litvak...> ;Clinical Cancer Research. 2016 Jul 15
878 citations
Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial
Scott J. Antonia, Jose A. Lopez-Martin, Johanna C. Bendell, Patrick A. Ott, Matthew H. Taylor, Joseph Paul Eder, Dirk Jäger, M. Catherine Pietanza, Dung T. Le, Filippo...> ;The Lancet. Oncology. 2016 Jul 1
132 citations
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Paul A. Bunn, John D. Minna, Alexander Augustyn, Adi F. Gazdar, Youcef Ouadah, Mark A. Krasnow, Anton Berns, Elisabeth Brambilla, Natasha Rekhtman, Pierre P. Massion, ...> ;Journal of Thoracic Oncology. 2016 Apr 1
7 citations
Using a Population-Based Analysis to Determine the Management and Treatment of Early-Stage Small-Cell Lung Cancer
M. Catherine Pietanza> ;Journal of Clinical Oncology. 2016 Apr 1
4 citations
Phase II Study of a Non-Platinum–Containing Doublet of Paclitaxel and Pemetrexed with Bevacizumab as Initial Therapy for Patients with Advanced Lung Adenocarcinomas
Maria Catherine Pietanza, Matthew D. Hellmann, John J. Fiore, Stephanie Smith-Marrone, Ethan Basch, Lawrence H. Schwartz, Michelle S. Ginsberg, Marwan Shouery, Samanth...> ;Journal of Thoracic Oncology. 2016 Jun 1
38 citations
Comparison of CT volumetric measurement with RECIST response in patients with lung cancer
Sara A. Hayes, Maria Catherine Pietanza, D. O’Driscoll, Junting Zheng, Chaya S. Moskowitz, Mark G. Kris, Michelle S. Ginsberg> ;European Journal of Radiology. 2016 Mar 1
15 citations
Bronchial and Thymic Carcinoid Tumors
Anya Litvak, M. Catherine Pietanza> ;Hematology/oncology Clinics of North America. 2016 Feb 1
231 citations
Treatment of Small-Cell Lung Cancer: American Society of Clinical Oncology Endorsement of the American College of Chest Physicians Guideline
Charles M. Rudin, Nofisat Ismaila, Christine L. Hann, Narinder K. Malhotra, Benjamin Movsas, Kim Norris, M. Catherine Pietanza, Suresh S. Ramalingam, Andrew T. Turrisi...> ;Journal of Clinical Oncology. 2015 Sep 8
34 citations
Feasibility and clinical impact of sharing patient-reported symptom toxicities and performance status with clinical investigators during a phase 2 cancer treatment trial.
Ethan Basch, William A. Wood, Deborah Schrag, Camelia S. Sima, Mary Shaw, Lauren J. Rogak, Mark G. Kris, Marwan Shouery, Antonia V. Bennett, Thomas M. Atkinson, M. Cat...> ;Clinical Trials. 2016 Jun 1
374 citations
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
Laura Saunders, Alexander J. Bankovich, Wade C. Anderson, Monette Aujay, Sheila Bheddah, KristenAnn Black, Desai Radhika Chetan, Paul Anthony Escarpe, Johannes Hampl, ...> ;Science Translational Medicine. 2015 Aug 26
153 citations
Small cell lung cancer: will recent progress lead to improved outcomes?
M. Catherine Pietanza, Lauren Averett Byers, John D. Minna, Charles M. Rudin> ;Clinical Cancer Research. 2015 May 15
44 citations
Trial of a 5-day dosing regimen of temozolomide in patients with relapsed small cell lung cancers with assessment of methylguanine-DNA methyltransferase.
Marjorie G. Zauderer, A. Drilon, Kyuichi Kadota, Kety Huberman, Camelia S. Sima, Isabella Bergagnini, Dyana K. Sumner, William D. Travis, Adriana Heguy, Michelle S. Gi...> ;Lung Cancer. 2014 Nov 1
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