LeeMKrugMD

Oncology • New York, NY

Hematologic Oncology

Associate Professor, Medicine, Weill Cornell Medical College

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Office
1275 York Ave
MSKCC, Dept Thoracic Oncology
New York, NY 10021
Phone(646) 227-3813
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Education & Training

Memorial Sloan-Kettering Cancer CenterFellowship, Hematology/Oncology, 1997 - 2000
Johns Hopkins UniversityResidency, Internal Medicine, 1994 - 1997
Washington University School of Medicine in St. LouisClass of 1994

Certifications & Licensure

NY State Medical License 1997 - 2023
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Top Doctors: New York Metro Area Castle Connolly, 2010-2014

Clinical Trials

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent Start of enrollment: 2015 Oct 01Gandara D.R.,Kalemkerian G.P.,Krug L.M.,Wozniak A.
Consortium for the Sharing of Germ Line DNA and Tissue From Subjects With Mesothelioma Start of enrollment: 2011 Jun 01Peikert, T.,Brahmer, J.R.,Sterman, D.,Ohar, J.M.,Krug, L.M.,Pass, H.I.
Mesothelioma From a Patient Perspective: A Survey of Psychosocial Needs and Exploration of Online Support for Patients Start of enrollment: 2011 May 01Key, R.G.,Krug, L.
Immunization of Small Cell Lung Cancer Patients With a Pentavalent Vaccine Composed of KLH-conjugates of GD2L, GD3L, Globo H, Fucosyl GM1, and N-Propionylated Polysialic Acid Start of enrollment: 2011 May 01Krug, L.,Pietanza, M.
Randomized Phase II Study of Adjuvant WT-1 Analog Peptide Vaccine in Patients With Malignant Pleural Mesothelioma (MPM) After Completion of Combined Modality Therapy Start of enrollment: 2010 Dec 01Krug, L.,Rusch, V.
Phase II Study of Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity Start of enrollment: 2009 Dec 01Krug, L.
Phase II Toxicity Study Using Chemotherapy +/- Pleurectomy/Decortication Followed By Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma. Start of enrollment: 2008 Jul 01Gomez, D.,Krug, L.,Rimner, A.
Phase I/II Study of Obatoclax Mesylate (GX15-070MS), a Bcl-2 Antagonist, Plus Topotecan in Relapsed Small Cell Lung Carcinoma Start of enrollment: 2007 Aug 01Krug, L.M.,Rizvi, N.
Combination Chemotherapy With or Without Maintenance Sunitinib Malate (IND 74019; NSC 736511) For Untreated Extensive Stage Small Cell Lung Cancer: A Phase IB/Randomized Phase II Study Start of enrollment: 2007 Mar 01Ansari, R.H.,Atkins, J.N.,Baggstrom, M.Q.,Briccetti, F.M.,Chahin, M.,Feusner, J.H.,Grimm, R.A.,Grubbs, S.S.,Grunberg, S.M.,Kirshner, J.J.,Krug, L.M.,Kugler, J.W.,Langdon, R.M.,McIntyre, A.P.,Nattam, S.R.,...
Pilot Trial of a WT-1 Analog Peptide Vaccine in Patients With Thoracic and Myeloid Neoplasms Start of enrollment: 2006 Oct 01Krug, L.M.
Continuation Clinical Trial of Oral L-0010790038 in Advanced Cancer Start of enrollment: 2005 Aug 01Frankel, S.,Krug, L.
A Multiple-Dose Targeting Study of hu3S193 in Patients With Small Cell Lung Cancer Start of enrollment: 2004 Feb 01Divgi, C.R.,Krug, L.M.
A Multicenter Phase II Trial of Neo-Adjuvant Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation for Pleural Mesothelioma Start of enrollment: 2003 Jul 01Krug, L.M.
A Phase I Study of Imatinib (Gleevec) in Combination With Irinotecan and Cisplatin in Extensive Stage Small Cell Lung Cancer Start of enrollment: 2002 Jul 01Krug, L.M.
Phase II Study Of ET-743 In Patients With Unresectable Malignant Pleural Mesothelioma Start of enrollment: 2001 Jul 01Krug, L.M.
Vaccination of Non-Small Cell Lung Cancer Patients Against Mutated K-Ras: A Pilot Trial Start of enrollment: 1999 Jul 01Krug, L.M.
A Phase II Study of 10-Propargyl-10-Deazaaminopterin (PDX) in Patients With Advanced Non-Small Cell Lung Cancer Start of enrollment: 1999 Jul 01Krug, L.M.
Immunization Using Polysialic Acid-KLH or N-Propionylated Polysialic Acid-KLH Conjugate Plus the Immunological Adjuvant QS-21 in Patients With Small Cell Lung Cancer Who Have Achieved a Major Response to Initial Therapy Start of enrollment: 1998 Aug 01Krug, L.M.
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Publications & Presentations

PubMed

Real-World Clinical Impact of Immune Checkpoint Inhibitors in Patients With Advanced/Metastatic Non-Small Cell Lung Cancer After Platinum Chemotherapy.
Schwartzberg, L., Korytowsky, B., Penrod, J. R., Zhang, Y., Le, T. K., Batenchuk, C., Krug, L.> ;Clinical lung cancer. 2019 May 28
Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell L...
M. Catherine Pietanza, Saiama N. Waqar, Lee M. Krug, Afshin Dowlati, Christine L. Hann, Alberto Chiappori, Taofeek K. Owonikoko, Kaitlin M. Woo, Robert J. Cardnell, Ju...> ;Journal of Clinical Oncology. 2018 Jun 15
Making Lung Cancer Clinical Trials More Inclusive: Recommendations for Expanding Eligibility Criteria.
Bonomi, P., Blumenthal, G. M., Ferris, A. S., Stewart, D. J., Selig, W. K., Krug, L. M., Allen, J. D., Ison, G., Langer, C. J., Melemed, A. S., Odogwu, L., Roy, U. B.,...> ;Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2018 May 26
3 citations
A Randomized Phase II Trial of Adjuvant Galinpepimut-S, WT-1 Analogue Peptide Vaccine, After Multimodality Therapy for Patients with Malignant Pleural Mesothelioma.
Zauderer, M. G., Tsao, A. S., Dao, T., Panageas, K. S., Lai, W. V., Rimner, A., Rusch, V. W., Adusumilli, P. S., Ginsberg, M. S., Gomez, D. R., Rice, D. C., Mehran, R....> ;Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Oct 4
2 citations
Patterns of failure in limited-stage small cell lung cancer: Implications of TNM stage for prophylactic cranial irradiation.
Wu, A. J., Gillis, A., Foster, A., Woo, K. M., Zhang, Z., Gelblum, D. Y., Downey, R. J., Rosenzweig, K. E., Ong, L., Perez, C. A., Pietanza, M. C., Krug, L. M., Rudin,...> ;Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2017 Aug 6
4 citations
Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma.
Shaikh, F., Zauderer, M. G., von Reibnitz, D., Wu, A. J., Yorke, E. D., Foster, A., Shi, W., Zhang, Z., Adusumilli, P. S., Rosenzweig, K. E., Krug, L. M., Rusch, V. W....> ;Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2017 Mar 28
3 citations
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung...
M. Catherine Pietanza, Anya Litvak, Anna M. Varghese, Lee M. Krug, Martin Fleisher, Jerrold B. Teitcher, Andrei I. Holodny, C. S. Sima, Kaitlin M. Woo, Kenneth K. Ng, ...> ;Lung Cancer. 2016 Sep 1
6 citations
Phase II Study of Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) As Part of Lung-Sparing Multimodality Therapy in Patients With Malignant Pleural...
Rimner, A., Zauderer, M. G., Gomez, D. R., Adusumilli, P. S., Parhar, P. K., Wu, A. J., Woo, K. M., Shen, R., Ginsberg, M. S., Yorke, E. D., Rice, D. C., Tsao, A. S., ...> ;Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Jun 22
3 citations
Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes.
Naidoo, J., Santos-Zabala, M. L., Iyriboz, T., Woo, K. M., Sima, C. S., Fiore, J. J., Kris, M. G., Riely, G. J., Lito, P., Iqbal, A., Veach, S., Smith-Marrone, S., Sar...> ;Clinical lung cancer. 2016 Feb 24
Contemporary Analysis of Prognostic Factors in Patients with Unresectable Malignant Pleural Mesothelioma.
Billé, A., Krug, L. M., Woo, K. M., Rusch, V. W., Zauderer, M. G.> ;Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 Feb 6
22 citations
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Bunn, P. A., Minna, J. D., Augustyn, A., Gazdar, A. F., Ouadah, Y., Krasnow, M. A., Berns, A., Brambilla, E., Rekhtman, N., Massion, P. P., Niederst, M. J., Peifer, M....> ;Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 Feb 2
232 citations
Non-Small Cell Lung Cancer, Version 6.2015.
Ettinger, D. S., Wood, D. E., Akerley, W., Bazhenova, L. A., Borghaei, H., Camidge, D. R., Cheney, R. T., Chirieac, L. R., D'Amico, T. A., Demmy, T. L., Dilling, T. J....> ;Journal of the National Comprehensive Cancer Network : JNCCN. 2015 May 13
Non-small cell lung cancer, version 1.2015.
Ettinger, D. S., Wood, D. E., Akerley, W., Bazhenova, L. A., Borghaei, H., Camidge, D. R., Cheney, R. T., Chirieac, L. R., D'Amico, T. A., Demmy, T. L., Dilling, T. J....> ;Journal of the National Comprehensive Cancer Network : JNCCN. 2014 Dec 17
1 citation
Trial of a 5-day dosing regimen of temozolomide in patients with relapsed small cell lung cancers with assessment of methylguanine-DNA methyltransferase.
Zauderer, M. G., Drilon, A., Kadota, K., Huberman, K., Sima, C. S., Bergagnini, I., Sumner, D. K., Travis, W. D., Heguy, A., Ginsberg, M. S., Holodny, A. I., Riely, G....> ;Lung cancer (Amsterdam, Netherlands). 2014 Sep 10
The ITMIG/IASLC thymic epithelial tumors staging project: A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classificati...
F.Y. Bhora, David J. Chen, Frank C. Detterbeck, Hisao Asamura, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Kazuya Kondo, Marco Lu...> ;Journal of Thoracic Oncology. 2014 Sep 1
Randomized phase II trial of pemetrexed/cisplatin with or without CBP501 in patients with advanced malignant pleural mesothelioma.
Lee M. Krug, Antoinette J. Wozniak, Hedy L. Kindler, Ronald Feld, Marianna Koczywas, Jose Luis Morero, Cristina P. Rodriguez, Helen J. Ross, Julie E. Bauman, Sergey Or...> ;Lung Cancer. 2014 Sep 1
5 citations
Failure patterns after hemithoracic pleural intensity modulated radiation therapy for malignant pleural mesothelioma.
Rimner, A., Spratt, D. E., Zauderer, M. G., Rosenzweig, K. E., Wu, A. J., Foster, A., Yorke, E. D., Adusumilli, P. S., Rusch, V. W., Krug, L. M.> ;International journal of radiation oncology, biology, physics. 2014 Jul 31
15 citations
Phase II study of the GI-4000 KRAS vaccine after curative therapy in patients with stage I-III lung adenocarcinoma harboring a KRAS G12C, G12D, or G12V mutation.
Chaft, J. E., Litvak, A., Arcila, M. E., Patel, P. R., D'Angelo, S. P., Krug, L. M., Rusch, V. W., Mattson, A., Coeshott, C., Park, B. J., Apelian, D. M., Kris, M. G.,...> ;Clinical lung cancer. 2014 Jul 22
20 citations
Small-cell lung cancers in patients who never smoked cigarettes.
Anna M. Varghese, Maureen F. Zakowski, Helena A. Yu, Helen Won, Gregory J. Riely, Lee M. Krug, Mark G. Kris, Natasha Rekhtman, Marc Ladanyi, Lu Wang, Michael F. Berger...> ;Journal of Thoracic Oncology. 2014 Jun 1
17 citations
Vinorelbine and gemcitabine as second- or third-line therapy for malignant pleural mesothelioma.
Zauderer, M. G., Kass, S. L., Woo, K. M., Sima, C. S., Ginsberg, M. S., Krug, L. M.> ;Lung cancer (Amsterdam, Netherlands). 2014 Apr 3
2 citations
The challenge of malignant pleural mesothelioma: new directions.
Rusch, V. W., Rimner, A., Krug, L. M.> ;Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 Feb 13
4 citations
Clinical Characteristics of Patients with Malignant Pleural Mesothelioma Harboring Somatic BAP1 Mutations
Marjorie G. Zauderer, Matthew J. Bott, Robert McMillan, Camelia S. Sima, Valerie W. Rusch, Lee M. Krug, Marc Ladanyi> ;Journal of Thoracic Oncology. 2013 Nov 1
5 citations
Phase II Trial of Neoadjuvant Bevacizumab Plus Chemotherapy and Adjuvant Bevacizumab in Patients with Resectable Nonsquamous Non–Small-Cell Lung Cancers
Jamie E. Chaft, Valerie W. Rusch, Michelle S. Ginsberg, Paul K. Paik, David J. Finley, Mark G. Kris, Katharine A.R. Price, Christopher G. Azzoli, Matthew G. Fury, Greg...> ;Journal of Thoracic Oncology. 2013 Aug 1
4 citations
Risk of hemoptysis in patients with resected squamous cell and other high-risk lung cancers treated with adjuvant bevacizumab.
Hellmann, M. D., Chaft, J. E., Rusch, V. W., Ginsberg, M. S., Finley, D. J., Kris, M. G., Price, K. A., Azzoli, C. G., Fury, M. G., Riely, G. J., Krug, L. M., Downey, ...> ;Cancer chemotherapy and pharmacology. 2013 Jul 3
19 citations
Non-small cell lung cancer, version 2.2013: Featured updates to the NCCN guidelines
David S. Ettinger, Wallace Akerley, Hossein Borghaei, Andrew C. Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd L. Demmy, Ramaswamy Govindan, Fre...> ;Journal of The National Comprehensive Cancer Network. 2013 Jun 1
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