LeeMKrugMD

Oncology • New York, NY

Associate Professor, Medicine, Weill Cornell Medical College

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Office
1275 York Ave
MSKCC, Dept Thoracic Oncology
New York, NY 10021
Phone+1 646-227-3813
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1997 - 2000
Johns Hopkins UniversityResidency, Internal Medicine, 1994 - 1997
Washington University in St. Louis School of MedicineClass of 1994

Certifications & Licensure

NY State Medical License 1997 - 2023
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Top Doctors: New York Metro Area Castle Connolly, 2010-2014

Clinical Trials

10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer Start of enrollment: 1999 Jul 01
Completed
Phase 2
Vaccine Therapy Plus QS21 in Treating Patients With Small Cell Lung Cancer That Has Responded to Initial Therapy Start of enrollment: 1998 Aug 01
Completed
Phase 2
Vaccine Therapy and Sargramostim in Treating Patients With Non-small Cell Lung Cancer Start of enrollment: 1999 Jul 01
Completed
Phase 1
Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma Start of enrollment: 2001 Jul 01
Terminated
Phase 2
Imatinib Mesylate and Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer Start of enrollment: 2002 Jul 01
Completed
Phase 1
A Multicenter Phase II Trial of Neo-Adjuvant Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation for Pleural Mesothelioma Start of enrollment: 2003 Jul 01
Monoclonal Antibody Therapy in Treating Patients With Progressive Small Cell Lung Cancer (SCLC) Start of enrollment: 2004 Jul 26
Completed
Phase 1
Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma Start of enrollment: 2006 Oct 01
Completed
Phase 1
Cisplatin or Carboplatin, and Etoposide With or Without Sunitinib Malate in Treating Patients With Extensive-Stage Small Cell Lung Cancer Start of enrollment: 2007 Mar 15
Completed
Phase 1, Phase 2
Obatoclax Mesylate and Topotecan Hydrochloride in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer or Advanced Solid Tumors Start of enrollment: 2007 Aug 01
Completed
Phase 1, Phase 2
Continuation Clinical Trial of Oral L-0010790038 in Advanced Cancer Start of enrollment: 2005 Aug 01
Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma Start of enrollment: 2008 Oct 11
Active, not recruiting
Phase 2
Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity Start of enrollment: 2009 Dec 01
Completed
Phase 2
WT-1 Analog Peptide Vaccine in Malignant Pleural Mesothelioma After Combined Modality Therapy Start of enrollment: 2010 Dec 21
Completed
Phase 2
Immunization With a Pentavalent Vaccine Composed of KLH-conjugates of GD2L, GD3L, Globo H, Fucosyl GM1, and N-Propionylated Polysialic Acid Start of enrollment: 2011 May 01
Completed
Phase 1
Psychosocial Needs and Exploration of Online Support for Patients With Mesothelioma Start of enrollment: 2011 May 01
Active, not recruiting
Not Applicable
Do Your Genes Put You at a Higher Risk of Developing Mesothelioma Start of enrollment: 2011 Jun 01
Completed
Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent Start of enrollment: 2016 Mar 15
Completed
Phase 2
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Publications & Presentations

PubMed

5 citations
Phase II Study of Arginine Deprivation Therapy With Pegargiminase in Patients With Relapsed Sensitive or Refractory Small-cell Lung Cancer.
Peter E Hall, Neal Ready, Amanda Johnston, John S. Bomalaski, Ralph Venhaus, Michael Sheaff, Lee M. Krug, Peter W. Szlosarek> ;Clinical Lung Cancer. 2020 Jul 30
17 citations
Real-World Clinical Impact of Immune Checkpoint Inhibitors in Patients With Advanced/Metastatic Non-Small Cell Lung Cancer After Platinum Chemotherapy.
Lee S. Schwartzberg, Beata Korytowsky, John R. Penrod, Ying Zhang, T. Kim Le, Cory Batenchuk, Lee M. Krug> ;Clinical Lung Cancer. 2019 Apr 19
162 citations
Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell L...
M. Catherine Pietanza, Saiama N. Waqar, Lee M. Krug, Afshin Dowlati, Christine L. Hann, Alberto Chiappori, Taofeek K. Owonikoko, Kaitlin M. Woo, Robert J. Cardnell, Ju...> ;Journal of Clinical Oncology. 2018 Jun 15
6 citations
Making Lung Cancer Clinical Trials More Inclusive: Recommendations for Expanding Eligibility Criteria.
Philip Bonomi, Gideon M. Blumenthal, Andrea Ferris, David J. Stewart, Wendy Selig, Lee M. Krug, Jeff Allen, Gwynn Ison, Corey J. Langer, Allen S. Melemed, Lauretta Odo...> ;Journal of Thoracic Oncology. 2018 Jun 1
63 citations
Phase I Study of Apitolisib (GDC-0980), Dual Phosphatidylinositol-3-Kinase and Mammalian Target of Rapamycin Kinase Inhibitor, in Patients with Advanced Solid Tumors
Saoirse Dolly, Andrew J. Wagner, Johanna C. Bendell, Hedy L. Kindler, Lee M. Krug, Tanguy Y. Seiwert, Marjorie G. Zauderer, Martijn P. Lolkema, Doris Apt, Ru Fang Yeh,...> ;Clinical Cancer Research. 2016 Jun 15
28 citations
A Randomized Phase II Trial of Adjuvant Galinpepimut-S, WT-1 Analogue Peptide Vaccine, After Multimodality Therapy for Patients with Malignant Pleural Mesothelioma.
Marjorie G. Zauderer, Anne S. Tsao, Tao Dao, Katherine S. Panageas, W. Victoria Lai, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, Michelle S. Ginsberg, Dani...> ;Clinical Cancer Research. 2017 Jan 1
22 citations
Patterns of failure in limited-stage small cell lung cancer: Implications of TNM stage for prophylactic cranial irradiation.
Abraham J. Wu, Andrea Gillis, A. Foster, Kaitlin M. Woo, Zhigang Zhang, Daphna Y. Gelblum, Robert J. Downey, Kenneth E. Rosenzweig, Leonard Ong, C.A. Perez, M. Catheri...> ;Radiotherapy and Oncology. 2017 Oct 1
29 citations
Improved Outcomes with Modern Lung-Sparing Trimodality Therapy in Patients with Malignant Pleural Mesothelioma.
F. Shaikh, Marjorie G. Zauderer, Donata von Reibnitz, Abraham J. Wu, Ellen Yorke, A. Foster, Weiji Shi, Zhigang Zhang, Prasad S. Adusumilli, Kenneth E. Rosenzweig, Lee...> ;Journal of Thoracic Oncology. 2017 Jun 1
42 citations
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung...
M. Catherine Pietanza, Anya Litvak, Anna M. Varghese, Lee M. Krug, Martin Fleisher, Jerrold B. Teitcher, Andrei I. Holodny, C.S. Sima, Kaitlin M. Woo, Kenneth K.-S. Ng...> ;Lung Cancer. 2016 Sep 1
127 citations
The IASLC Lung Cancer Staging Project: Methodology and Validation Used in the Development of Proposals for Revision of the Stage Classification of NSCLC in the Forthco...
Frank C. Detterbeck, Kari Chansky, Patti A. Groome, Vanessa Bolejack, John Crowley, Lynn Shemanski, Catherine Kennedy, Mark Krasnik, Michael D Peake, Ramón Rami-Porta,...> ;Journal of Thoracic Oncology. 2016 Sep 1
73 citations
Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes
Jarushka Naidoo, Maria Laureana Santos-Zabala, Tunc Iyriboz, Kaitlin M. Woo, Camelia S. Sima, John J. Fiore, Mark G. Kris, Gregory J. Riely, Piro Lito, Afsheen Iqbal, ...> ;Clinical Lung Cancer. 2016 Sep 1
331 citations
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eigh...
William D. Travis, Hisao Asamura, Alexander A. Bankier, Mary Beth Beasley, Frank C. Detterbeck, Douglas B. Flieder, Jin Mo Goo, Heber MacMahon, David P. Naidich, Andre...> ;Journal of Thoracic Oncology. 2016 Aug 1
95 citations
Phase II Study of Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) As Part of Lung-Sparing Multimodality Therapy in Patients With Malignant Pleural...
Andreas Rimner, Marjorie G. Zauderer, Daniel R. Gomez, Prasad S. Adusumilli, Preeti K. Parhar, Abraham J. Wu, Kaitlin M. Woo, Ronglai Shen, Michelle S. Ginsberg, Ellen...> ;Journal of Clinical Oncology. 2016 Sep 27
107 citations
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Paul A. Bunn, John D. Minna, Alexander Augustyn, Adi F. Gazdar, Youcef Ouadah, Mark A. Krasnow, Anton Berns, Elisabeth Brambilla, Natasha Rekhtman, Pierre P. Massion, ...> ;Journal of Thoracic Oncology. 2016 Apr 1
40 citations
Contemporary Analysis of Prognostic Factors in Patients with Unresectable Malignant Pleural Mesothelioma.
Andrea Billè, Lee M. Krug, Kaitlin M. Woo, Valerie W. Rusch, Marjorie G. Zauderer> ;Journal of Thoracic Oncology. 2016 Feb 1
1758 citations
The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer.
Peter Goldstraw, Kari Chansky, John Crowley, Ramón Rami-Porta, Hisao Asamura, Wilfried Ernst Erich Eberhardt, Andrew G. Nicholson, Patti A. Groome, Alan Mitchell, Vane...> ;Journal of Thoracic Oncology. 2016 Jan 1
424 citations
Non-Small cell lung cancer, version 6.2015: Featured updates to the NCCN guidelines
David S. Ettinger, Douglas E. Wood, Wallace Akerley, Lyudmila Bazhenova, Hossein Borghaei, D.R. Camidge, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd...> ;Journal of The National Comprehensive Cancer Network. 2015 May 1
114 citations
Vorinostat in patients with advanced malignant pleural mesothelioma who have progressed on previous chemotherapy (VANTAGE-014): a phase 3, double-blind, randomised, pl...
Lee M. Krug, Hedy L. Kindler, Hilary Calvert, Christian Manegold, Anne S. Tsao, Dean A. Fennell, Ronny Öhman, Ruth Plummer, Wilfried Eberhardt, Kazuya Fukuoka, Rabab G...> ;Lancet Oncology. 2015 Apr 1
81 citations
The tumoral and stromal immune microenvironment in malignant pleural mesothelioma: A comprehensive analysis reveals prognostic immune markers
Hideki Ujiie, Kyuichi Kadota, Jun-ichi Nitadori, Joachim G.J.V. Aerts, Kaitlin M. Woo, Camelia S. Sima, William D. Travis, David R. Jones, Lee M. Krug, Prasad S. Adusu...> ;OncoImmunology. 2015 Mar 19
125 citations
Non-small cell lung cancer, version 1.2015: Clinical practice guidelines in oncology
David S. Ettinger, Douglas E. Wood, Wallace Akerley, Lyudmila Bazhenova, Hossein Borghaei, D.R. Camidge, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd...> ;Journal of The National Comprehensive Cancer Network. 2014 Dec 1
38 citations
Phase II Study of the GI-4000 KRAS Vaccine After Curative Therapy in Patients With Stage I-III Lung Adenocarcinoma Harboring a KRAS G12C, G12D, or G12V Mutation
Jamie E. Chaft, Anya Litvak, Maria E. Arcila, Payal R. Patel, Sandra P. D'Angelo, Lee M. Krug, Valerie W. Rusch, Alicia Mattson, Claire Coeshott, Bernard J. Park, Davi...> ;Clinical Lung Cancer. 2014 Nov 1
34 citations
Trial of a 5-day dosing regimen of temozolomide in patients with relapsed small cell lung cancers with assessment of methylguanine-DNA methyltransferase.
Marjorie G. Zauderer, A. Drilon, Kyuichi Kadota, Kety Huberman, Camelia S. Sima, Isabella Bergagnini, Dyana K. Sumner, William D. Travis, Adriana Heguy, Michelle S. Gi...> ;Lung Cancer. 2014 Nov 1
73 citations
The ITMIG/IASLC thymic epithelial tumors staging project: A proposed lymph node map for thymic epithelial tumors in the forthcoming 8th edition of the TNM classificati...
F.Y. Bhora, David J. Chen, Frank C. Detterbeck, Hisao Asamura, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, James Huang, Jhingook Kim, Kazuya Kondo, Marco Lu...> ;Journal of Thoracic Oncology. 2014 Sep 1
17 citations
Randomized phase II trial of pemetrexed/cisplatin with or without CBP501 in patients with advanced malignant pleural mesothelioma.
Lee M. Krug, Antoinette J. Wozniak, Hedy L. Kindler, Ronald Feld, Marianna Koczywas, José L. Morero, Cristina P. Rodriguez, Helen J. Ross, Julie E. Bauman, Sergey Orlo...> ;Lung Cancer. 2014 Sep 1
36 citations
Failure patterns after hemithoracic pleural intensity modulated radiation therapy for malignant pleural mesothelioma.
Andreas Rimner, Daniel E. Spratt, Marjorie G. Zauderer, Kenneth E. Rosenzweig, Abraham J. Wu, A. Foster, Ellen Yorke, Prasad S. Adusumilli, Valerie W. Rusch, Lee M. Krug> ;International Journal of Radiation Oncology Biology Physics. 2014 Oct 1
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Hospital Affiliations

Memorial Sloan-Kettering Cancer CenterNew York, New York
The Mount Sinai HospitalNew York, New York

LeeMKrugMD

Dr. Krug is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Hospital Affiliations

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