MarkAndrewFryeMD

PubMed

• Measuring the exposome in bipolar disorder.
  Brandon J Coombes, Joanna M Biernacka, Mete Ercis, Aysegul Ozerdem, Marin Veldic, Balwinder Singh, Konstantinos N Lazaridis, Mark A Frye> ;Bipolar Disorders. 2024 May 1
• Partial wake therapy and luminotherapy as an adjunct to usual care in hospitalized patients with depression - a pilot study.
  Kathleen A Poppe, Sheryl L Brown, Carly Erickson, Ann M Hale, Bonnie L Johnson, Kelly L Jones, Vanessa K Pazdernik, Balwinder Singh, Simon Kung, Kathryn M Schak, Hanna...> ;Psychiatry Research. 2024 Apr 25
• Differential Serum Levels of CACNA1C, Circadian Rhythm and Stress Response Molecules in Subjects with Bipolar Disorder: Associations with Genetic and Clinical Factors.
  Brandon J Coombes, Vanessa Pazdernik, Barbara Gisabella, Joshua Hartley, Joanna M Biernacka, Harry Pantazopoulos, Obie Allen 4th, Mark A Frye, Matej Markota> ;Medrxiv. 2024 Apr 12
• Clinical and genetic contributions to medical comorbidity in bipolar disorder: a study using electronic health records-linked biobank data.
  Jorge A Sanchez-Ruiz, Brandon J Coombes, Vanessa M Pazdernik, Lindsay M Melhuish Beaupre, Greg D Jenkins, Richard S Pendegraft, Anthony Batzler, Susan L McElroy, Manue...> ;Molecular Psychiatry. 2024 Mar 28
• Cognitive effects of electroconvulsive therapy in depressed adolescents.
  Neera Ghaziuddin, Shawn M McClintock, Daniel F Maixner, Leslie R Miller, Mustafa Husain, Lee E Wachtel, Shan H Siddiqi, Michael Flood, Sally Weinstein, Mark A Frye, Ri...> ;Journal of Affective Disorders. 2024 Jul 1
• Change in neurocognitive functioning in patients with treatment-resistant depression with serial intravenous ketamine infusions: The Bio-K multicenter trial.
  Balwinder Singh, Sagar V Parikh, Jennifer L Vande Voort, Vanessa K Pazdernik, Eric D Achtyes, Fernando S Goes, Anastasia K Yocum, Louis Nykamp, Alexis Becerra, LeAnn S...> ;Psychiatry Research. 2024 May 1
• Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.
  Anna H Ou, Sara B Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlun...> ;Translational Psychiatry. 2024 Feb 23
• Sex differences in effectiveness and adverse effects of mood stabilizers and antipsychotics: A systematic review.
  Mete Ercis, Jorge A Sanchez-Ruiz, Lauren M Webb, Melissa Solares-Bravo, Hannah K Betcher, Katherine M Moore, Mark A Frye, Marin Veldic, Aysegul Ozerdem> ;Journal of Affective Disorders. 2024 May 1
• Reply to Sun: Dynamic and accessible pharmacogenomic results: a response to pharmacogenomic testing for antidepressant treatment selection.
  Mark A Frye, Charles B Nemeroff> ;Neuropsychopharmacology. 2024 Apr 1
• Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.
  Nicolas A Nuñez, Brandon J Coombes, Lindsay Melhuish Beaupre, Aysegul Ozerdem, Manuel Gardea Resendez, Francisco Romo-Nava, David J Bond, Marin Veldic, Balwinder Singh...> ;Translational Psychiatry. 2024 Feb 13
• Fine-mapping genomic loci refines bipolar disorder risk genes.
  Koromina, M., Ravi, A., Panagiotaropoulou, G., Schilder, B., Humphrey, J., Braun, A., Bidgeli, T., Chatzinakos, C., Coombes, B., Kim, J., Liu, X., Terao, C., O 'Connel...> ;Medrxiv. 2024 Feb 13
• 1 citations
  High Probability of Gene-Drug Interactions Associated with Medication Side Effects in Adolescent Depression: Results from a Randomized Controlled Trial of Pharmacogene...
  Nooraeen, S., Geske, J., Orth, S., Vande Voort, J., Croarkin, P., Shekunov, J., Romanowicz, M., Frye, M.> ;Journal of Child and Adolescent Psychopharmacology. 2024 Feb 1
• 1 citations
  Treatment-resistant depression patients with baseline suicidal ideation required more treatments to achieve therapeutic response with ketamine/esketamine.
  Vande Voort, J., Singh, B., Frye, M., Kung, S., Pazdernik, V.> ;Journal of Affective Disorders. 2024 Apr 15
• Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
  Panagiotaropoulou, G., Hellberg, K., Coleman, J., Seok, D., Kalman, J., , , , Mitchell, P., Schofield, P., Forstner, A., Bauer, M., Scott, L., Pato, C., Pato, M., Li, ...> ;Medrxiv. 2024 Jan 30
• 1 citations
  Current Status and Treatment of Rapid Cycling Bipolar Disorder.
  Miola, A., Tondo, L., Baldessarini, R., Frye, M.> ;Journal of Clinical Psychopharmacology. 2024 Jan 16
• Digital Phenotyping for Mood Disorders: Methodology-Oriented Pilot Feasibility Study.
  Gardea-Resendez, M., Langholm, C., Xiong, A., Laivell, J., Stoppel, C., Harper, L., Volety, R., Walker, A., D'Mello, R., Byun, A., Zandi, P., Breitinger, S., Goes, F.,...> ;Journal of Medical Internet Research. 2023 Dec 29
• 1 citations
  Clinical outcomes in the biomarkers of ketamine (Bio-K) study of open-label IV ketamine for refractory depression.
  Parikh, S., Vande Voort, J., Yocum, A., Achtyes, E., Goes, F., Nykamp, L., Singh, B., Lopez-Vives, D., Sera, C., Maixner, D., Tarnal, V., Severe, J., Bartek, S., Tye, ...> ;Journal of Affective Disorders. 2024 Mar 1
• 2 citations
  Classifying and clustering mood disorder patients using smartphone data from a feasibility study.
  Langholm, C., Gray, L., Walker, A., Xiong, A., Stopel, C., Zandi, P., Breitinger, S., Goes, F., Frye, M., Torous, J.> ;NPJ Digital Medicine. 2023 Dec 21
• Effect of non-invasive spinal cord stimulation in unmedicated adults with major depressive disorder: a pilot randomized controlled trial and induced current flow pattern.
  Francisco Romo-Nava, Oluwole O Awosika, Ishita Basu, Thomas J Blom, Jeffrey Welge, Abhishek Datta, Alexander Guillen, Anna I Guerdjikova, David E Fleck, Georgi Georgie...> ;Molecular Psychiatry. 2023 Dec 20
• 1 citations
  Factors associated with suicide attempts in the antecedent illness trajectory of bipolar disorder and schizophrenia.
  Miola, A., Gardea-Reséndez, M., Ortiz-Orendain, J., Nunez, N., Coombes, B., Salgado, M., Gruhlke, P., Michel, I., Bostwick, J., McKean, A., Ozerdem, A., Frye, M., Erci...> ;International Journal of Bipolar Disorders. 2023 Dec 8
• Age-Dependent Sex Differences in the Prevalence of Selective Serotonin Reuptake Inhibitor Treatment: A Retrospective Cohort Analysis.
  Jorge A Sanchez-Ruiz, Nicole I Leibman, Nicholas B Larson, Gregory D Jenkins, Ahmed T Ahmed, Nicolas A Nunez, Joanna M Biernacka, Stacey J Winham, Richard M Weinshilbo...> ;Journal of Women's Health. 2023 Nov 1
• 15 citations
  GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
  Anna R Docherty, Niamh Mullins, Allison E Ashley-Koch, Xuejun Qin, Jonathan R I Coleman, Andrey Shabalin, JooEun Kang, Balasz Murnyak, Frank Wendt, Mark Adams, Adrian ...> ;The American Journal of Psychiatry. 2023 Oct 1
• 1 citations
  Pharmacogenomic testing for antidepressant treatment selection: lessons learned and roadmap forward.
  Mark A Frye, Charles B Nemeroff> ;Neuropsychopharmacology. 2024 Jan 1
• 2 citations
  Antecedents to first episode psychosis and mania: Comparing the initial prodromes of schizophrenia and bipolar disorder in a retrospective population cohort.
  Javier Ortiz-Orendain, Manuel Gardea-Resendez, Santiago Castiello-de Obeso, Raphael Golebiowski, Brandon Coombes, Peggy M Gruhlke, Ian Michel, J Michael Bostwick, Robe...> ;Journal of Affective Disorders. 2023 Nov 1
• 11 citations
  Patterns of pharmacotherapy for bipolar disorder: A GBC survey.
  Balwinder Singh, Anastasia K Yocum, Rebecca Strawbridge, Katherine E Burdick, Caitlin E Millett, Amy T Peters, Sarah H Sperry, Giovanna Fico, Eduard Vieta, Norma Verdo...> ;Bipolar Disorders. 2024 Feb 1
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Journal Articles

• Research Paper Sex-Specific Effects of Gain-of-Function P2RX7 Variation on Bipolar Disorder  
  William V Bobo, Mark A Frye, ScienceDirect
• Supraphysiologic doses of levothyroxine as adjunctive therapy in bipolar depression: A randomized, double-blind, placebo-controlled study  
  Stamm TJ, Lewitzka U, Sauer C, Pilhatsch M, Smolka MN, Koeberle U, Adli M, Ricken R, Scherk H, Frye MA, Juckel G, Assion HJ, Gitlin M, Whybrow PC, Bauer M, J Clin Psychiatry, 1/1/2014
• A multinational study to pilot the modified Hypomania Checklist (mHCL) in the assessment of mixed depression  
  Altinbas K, Ozerdem A, Prieto ML, Fuentes ME, Yalin N, Ersoy Z, Aydemir O, Quiroz D, Oztekin S, Geske JR, Feeder SE, Angst J, Frye MA, J Affect Disord, 1/1/2014
• More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany  
  Post RM, Altshuler LL, Leverich GS, Frye MA, Suppes T, McElroy SL, Keck PE Jr, Nolen WA, Kupka RW, Grunze H, Rowe M, J Nerv Ment Dis, 1/1/2014
• More pernicious course of bipolar disorder in the United States than in many European countries: Implications for policy and treatment  
  Post RM, Altshuler L, Kupka R, McElroy S, Frye MA, Rowe M, Leverich GS, Grunze H, Suppes T, Keck PE Jr, Nolen WA, J Affect Disord, 1/1/2014
• Paradigm shift: preliminary clinical categorization of ultra-high risk for childhood bipolar disorder to facilitate studies on prevention  
  Post RM, Chang K, Frye MA, J Clin Psychiatry, 1/1/2013
• Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study  
  Abulseoud O, Gitlin M, Altshuler L, Frye MA, Brain Behav, 1/1/2013
• Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force  
  Frey BN, Andreazza AC, Houenou J, Jamain S, Goldstein BI, Frye MA, Leboyer M, Berk M, Malhi GS, Lopez-Jaramillo C, Taylor VH, Dodd S, Frangou S, Hall GB, Fernandes BS,..., Aust N Z J Psychiatry, 1/1/2013
• Hypovitaminosis D in psychiatric inpatients: clinical correlation with depressive symptoms, cognitive impairment, and prescribing practices  
  Leedahl DD, Cunningham JL, Drake MT, Mundis CB, Kung S, Frye MA, Lapid MI, Psychosomatics, 1/1/2013
• Assessment of response to lithium maintenance treatment in bipolar disorder: A consortium on lithium genetics (ConLiGen) report  
  Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng ..., PLoS ONE, 1/1/2013
• Feasibility evaluation of an interpersonal and social rhythm therapy group delivery model  
  Hoberg AA, Vickers KS, Ericksen J, Bauer G, Kung S, Stone R, Williams M, Moore MJ, Frye MA, Arch Psychiatr Nurs, 1/1/2013
• Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder  
  Malhi GS, Bargh DM, McIntyre R, Gitlin M, Frye MA, Bauer M, Berk M, Bipolar Disord, 1/1/2012
• Can bipolar disorder be viewed as a multi-system inflammatory disease?  
  Leboyer M, Soreca I, Scott J, Frye MA, Henry C, Tamouza R, Kupfer DJ, J Affect Disord, 1/1/2012
• Modafinil for bipolar depression with comorbid methamphetamine abuse  
  Camacho A, Ng B, Frye MA, Am J Addict, 1/1/2010
• Improving the design of maintenance studies for bipolar disorder  
  Gitlin MJ, Abulseoud O, Frye MA, Curr Med Res Opin, 1/1/2010
• Gender differences in the relationship between depressive symptoms and cravings in alcoholism  
  Boykoff N, Schneekloth TD, Hall-Flavin D, Loukianova L, Karpyak VM, Stevens SR, Biernacka JM, Mrazek DA, Frye MA, Am J Addict, 1/1/2010
• Utilization of residential addiction treatment in bipolar disorder  
  Hall-Flavin DK, Schneekloth TD, Loukianova LL, Karpyak VM, Lesnick TG, Biernacka JM, Mrazek DA, Frye MA, Am J Addict, 1/1/2010
• The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder  
  Arbuckle R, Frye MA, Brecher M, Paulsson B, Rajagopalan K, Palmer S, Degl’Innocenti A, Psychiatry Res, 1/1/2009
• Diagnostic dilemmas and clinical correlates of mixed states in bipolar depression  
  Frye MA, J Clin Psychiatry, 1/1/2008
• The alcohol withdrawal syndrome  
  McKeon A, Frye MA, Delanty N, J Neurol Neurosurg Psychiatry, 1/1/2008
• Increased suicidality in mania complicated by alcoholism  
  Fan AH, Frye MA, Masseling SJ, Hwang S, Cozzolino A, Kiriakos L, Mintz J, Sane N, Gitlin MJ, Altshuler L, Psychiatry, 1/1/2007
• Lack of mania prophylaxis associated with lamotrigine monotherapy in manic predominant bipolar I disorder  
  Dossett EC, Land AJ, Gitlin MJ, Frye MA, J Clin Psychiatry, 1/1/2007
• Free T4 index and clinical outcome in patients with depression  
  Abulseoud O, Sane N, Cozzolino A, Kiriakos L, Mehra V, Gitlin G, Masseling S, Whybrow P, Altshuler LL, Mintz J, Frye MA, J Affect Discord, 1/1/2007
• Modafinil in the treatment of bipolar depression: a placebo, controlled evaluation  
  Frye MA, Grunze H, Suppes T, McElroy SL, Keck PE, Althsuler LL, Leverich GL, Post RM, Am J Psychiatry, 1/1/2007
• Comorbid substance use disorder in women with bipolar disorder associated with criminal arrest  
  McDermott BE, Quanbeck CD, Frye MA, Bipolar Disord, 1/1/2007
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Abstracts/Posters

• Association between nicotine dependence, alcohol craving and high-risk situations to relapse in patients with alcohol use disorders
  Hitschfeld M, Schneekloth T, Ebbert J, Hall-Flavin D, Karpyak V, Geske M, Frye M, 167th American Psychiatric Association (APA) Annual Meeting, New York, NY, 1/3/2014
• Impact of smoking cessation on alcohol relapse after residential alcoholism treatment
  Hitschfeld M, Schneekloth T, Ebbert J, Hall-Flavin D, Karpyak V, Geske M, Frye M, 167th American Psychiatric Association (APA) Annual Meeting, New York, NY, 1/3/2014
• Use of a novel adjunctive clinical trial design to examine efficacy, safety of armodafinil for the treatment of bipolar I depression
  Frye MA, New Clinical Drug Evaluation Unit (NCDEU), Hollywood, FL, 1/28/2013
• Double-blind, placebo-controlled, multicenter trial of adjunctive armodafinil for the treatment of major depression associated with bipolar I disorder
  Calabrese J, Frye MA, New Clinical Drug Evaluation Unit (NCDEU), Hollywood, FL, 1/28/2013
• Electroconvulsive therapy use in adolescents at Mayo Clinic: A 20-year practice and outcomes review
  Puffer C, Wall C, Frye MA, American Psychiatric Association (APA), San Francisco, CA, 1/18/2013
• High frequency deep brain stimulation of the lateral habenula potentiates mesoaccumbens dopamine release
  Kim YS, Walker AJ, Abulseoud OA, Lee KH, Frye MA, Tye SJ, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• Inverse correlation between glutamate and craving for alcohol
  Frye MA, Hinton DJ, Karpyak VM, Abulseoud OA, Gunderson LJ, Feeder SE, Mrazek DA, Choi D-S, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• The phenomenology of high dose social drinking
  McKean AJS, Abulseoud OA, Port JD, Karpyak VM, Choi D-S, Hinton DJ, Gunderson LJ, Frye MA, Society of Biological Psychiatry 68th Annual Meeting (SOBP), San Francisco, CA, 1/16/2013
• Exploratory factor analysis of mixed depression utilizing the young mania rating scale and a modified version of hypomania checklist 32 (mHCL-32)
  Prieto ML, Ozerdem A, Quiroz D, Altinbas K, Aydemir O, Yalin N, Feeder SE, Geske JR, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• Comorbid cardiovascular disease and bipolar disorder: understanding the phenotype for subsequent inflammatory biomarker study
  Prieto ML, Biernacka JM, McElroy S, Crow J, Chauhan M, Fuentes ME, Choi D-S, Harper KL, Seymour LR, Geske JR, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• The clinical demographics of the Mayo Clinic bipolar disorder biobank
  Fuentes Salgado M, Kung S, McElroy S, Crow S, Chauhan M, Biernacka J, Seymour, Lisa, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
• Further exploration of the association of SLC6A4 with antidepressant-induced mania
  Biernacka J, Frye MA, 10th International Conference on Bipolar Disorders (ICBD), Miami, FL, 1/13/2013
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Lectures

• Bipolar Disorder: Think Global—Treat Local 
  Medellin, Colombia - 1/22/2014
• Bio-Banking Bipolar Disorder 
  Hanover, NH - 1/20/2014
• Novel Treatment Options for Bipolar Depression 
  Seoul, South Korea - 1/18/2014
• An Evidence Based Approach to Managing Bipolar Manic and Mixed Episodes 
  Newport, RI - 1/16/2014
• Mayo Clinic Bipolar Biobank: Focus on Metabolic Disorders 
  Madrid, Spain - 1/14/2014
• Dopamine, Subthalamic Nucleus Deep Brain Stimulation and Parkinson’s Disease: Implications for Mood Disorders; Mania Pre and Post DBS: Implications for Clinical Select... 
  Madrid, Spain - 1/14/2014
• Ethical Issues Surrounding Neurostimulation in Older Adults; Deep Brain Stimulation Considerations for Parkinson’s Disease Complicated by Mania Secondary to General Me... 
  New York, NY - 1/3/2014
• Biomarkers for Bipolar Depression—The Phenotype and Genotype of Antidepressant-Induced Mania 
  New York, NY - 1/3/2014
• Use of a Novel Adjunctive Clinical Trial Design to Examine Efficacy, Safety of Armodafinil for the Treatment of Major Depressive Episodes Associated With Bipolar I Dis... 
  Hollywood, FL - 1/29/2013
• Pharmacogenomics Targets for Depression and Bipolar Disorder; Bipolar Obesity, Genomic and Clinical Correlates 
  Quito, Ecuador - 1/22/2013
• Individualizing Treatment for Bipolar Depression—The Role of Biobanking and Biomarker Development 
  Cleveland, OH - 1/18/2013
• Inverse Correlation Between Glutamate and Craving for Alcohol 
  San Francisco, CA - 1/16/2013
• Psychiatric Genetics: Phenomics and Genomics and the Prospect of Personalized Medicine—Personalized medicine: 1st Experiences from the Mayo Bipolar Disorder 
  Bucharest, Romania - 1/11/2013
• Can You Distinguish Bipolar and Unipolar Depression?; Potential Biomarkers for Treatment Response in Bipolar Depression 
  Santiago, Chile - 1/1/2013
• NIMH Pathways Seminar 
  Bethesda, MD - 1/28/2012
• Being a Woman With Bipolar Disorder: A Focus on Addiction Comorbidity 
  Istanbul, Turkey - 1/14/2012
• Gender and Addiction / Mood - Implications for Clinical Practice 
  Santiago, Chile - 1/13/2012
• Standard of Care in the United States & Strategies for Preventing Depression in Bipolar Disorder 
  Tokyo, Japan - 1/28/2011
• Pharmacogenomic Targets in Bipolar Disorder 
  Santiago, Chile - 1/11/2011
• Where Are We With the Treatment of Bipolar I Disorder in the Short-Term? 
  Amsterdam, The Netherlands - 1/30/2010
• Pharmacogenomics of Antidepressant-Induced Mania 
  New Orleans, LA - 1/25/2010
• Beyond Maintenance Treatment: Protecting Patients From Destabilization 
  Sao Paulo, Brazil - 1/5/2009
• Bipolar Disorder & Mood Stabilizers—Treatment of Choice for Acute Mania, Bipolar Depression, and Maintenance Phase 
  Girne, Cyprus - 1/1/2009
• Neurobiology of Alcohol Addiction in Patients with Mood and Anxiety Disorders 
  Rochester, MN - 1/30/2008
• Nicotine Dependance and Mood Comorbidity: Approach to Treatment 
  Rochester, MN - 1/29/2008
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