MatthewBolandYurgelunMD

PubMed

• A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pa...
  Nicolette J Rodriguez, C Sloane Furniss, Matthew B Yurgelun, Chinedu Ukaegbu, Pamela E Constantinou, Ileana Fortes, Alyson Caruso, Alison N Schwartz, Jill E Stopfer, M...> ;Gastroenterology. 2024 Feb 5
• Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders.
  Huffman, B., Singh, H., Ali, L., Horick, N., Wang, S., Hoffman, M., Metayer, K., Murray, S., Bird, A., Abrams, T., Biller, L., Chan, J., Meyerhardt, J., McCleary, N., ...> ;Journal for Immunotherapy of Cancer. 2024 Jan 25
• 10 citations
  NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2024.
  Mary B Daly, Tuya Pal, Kara N Maxwell, Jane Churpek, Wendy Kohlmann, Zahraa AlHilli, Banu Arun, Saundra S Buys, Heather Cheng, Susan M Domchek, Susan Friedman, Veda Gi...> ;Journal of the National Comprehensive Cancer Network. 2023 Oct 1
• PREMM5 distinguishes sporadic from Lynch syndrome-associated MMR-deficient/MSI-high colorectal cancer.
  Renata L Sandoval, Miki Horiguchi, Chinedu Ukaegbu, C Sloane Furniss, Hajime Uno, Sapna Syngal, Matthew B Yurgelun> ;Familial Cancer. 2023 Oct 1
• 6 citations
  Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer.
  Ana Babic, Michael H Rosenthal, Tilak K Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harr...> ;Nature Communications. 2023 Jul 18
• 3 citations
  Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer.
  Harshabad Singh, Rachel B Keller, Kevin S Kapner, Julien Dilly, Srivatsan Raghavan, Chen Yuan, Elizabeth F Cohen, Michael Tolstorukov, Elizabeth Andrews, Lauren K Brai...> ;Clinical Cancer Research. 2023 Nov 14
• 1 citations
  Serendipity Strikes: How Pursuing Novel Hypotheses Shifted the Paradigm Regarding the Genetic Basis of Colorectal Cancer and Changed Cancer Therapy.
  C Richard Boland, Minoru Koi, Mary T Hawn, John M Carethers, Matthew B Yurgelun> ;Digestive Diseases and Sciences. 2023 Sep 1
• G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans.
  Victoire Cardot-Ruffino, Naima Bollenrucher, Luisa Delius, S Jennifer Wang, Lauren K Brais, Joshua Remland, C Elizabeth Keheler, Keri M Sullivan, Thomas A Abrams, Leah...> ;Journal for Immunotherapy of Cancer. 2023 Jun 1
• Is Appendiceal Cancer a Lynch Syndrome-Associated Cancer?
  Matthew B Yurgelun, David J Papke Jr, Mark S Redston> ;JAMA Oncology. 2023 Jun 1
• 8 citations
  Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation.
  Pratyusha Bala, Jonathan P Rennhack, Daulet Aitymbayev, Clare Morris, Sydney M Moyer, Gina N Duronio, Paul Doan, Zhixin Li, Xiaoyan Liang, Jason L Hornick, Matthew B Y...> ;Science Advances. 2023 Mar 29
• 3 citations
  Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.
  Kimberly Perez, Anna M Chiarella, James M Cleary, Nora Horick, Colin Weekes, Thomas Abrams, Lawrence Blaszkowsky, Peter Enzinger, Marios Giannakis, Lipika Goyal, Jeffr...> ;The Oncologist. 2023 May 8
• Clinical factors associated with skin neoplasms in individuals with Lynch syndrome in a longitudinal observational cohort.
  Connie S Zhong, Miki Horiguchi, Hajime Uno, Chinedu Ukaegbu, Anu Chittenden, Nicole R LeBoeuf, Sapna Syngal, Vinod E Nambudiri, Matthew B Yurgelun> ;Journal of the American Academy of Dermatology. 2023 Jun 1
• 24 citations
  Combined PD-1, BRAF and MEK inhibition in BRAFcolorectal cancer: a phase 2 trial.
  Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian Hess, Kelly Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, To...> ;Nature Medicine. 2023 Feb 1
• MyLynch: A Patient-Facing Clinical Decision Support Tool for Genetically-Guided Personalized Medicine in Lynch Syndrome.
  Stephen T Knapp, Anna Revette, Meghan Underhill-Blazey, Jill E Stopfer, Chinedu I Ukaegbu, Cole Poulin, Madison Parenteau, Sapna Syngal, Eunchan Bae, Timothy Bickmore,...> ;Cancers. 2023 Jan 6
• 2 citations
  Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer.
  Rachel B Keller, Tali Mazor, Lynette Sholl, Andrew J Aguirre, Harshabad Singh, Nilay Sethi, Adam Bass, Ankur K Nagaraja, Lauren K Brais, Emma Hill, Connor Hennessey, M...> ;JCO Precision Oncology. 2023 Jan 1
• Development and evaluation of INTGRATE: a platform for comprehensive assessment of the role of germline variants informed by tumor signature profile in Lynch syndrome.
  Raymond A Isidro, Anu Chittenden, McKenzie Walker, Alison Schwartz, Diane R Koeller, Connor P Hayes, Busra Unal, Monica Devi Manam, Ryan M Buehler, Danielle K Manning,...> ;Frontiers in Oncology. 2023 Jan 1
• 15 citations
  Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.
  Giulia Martina Cavestro, Alessandro Mannucci, Francesc Balaguer, Heather Hampel, Sonia S Kupfer, Alessandro Repici, Andrea Sartore-Bianchi, Toni T Seppälä, Vincenzo Va...> ;Clinical Gastroenterology and Hepatology. 2023 Mar 1
• 12 citations
  Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas.
  David J Papke Jr, Matthew B Yurgelun, Amy E Noffsinger, Kevin O Turner, Robert M Genta, Mark Redston> ;The New England Journal of Medicine. 2022 Nov 3
• 5 citations
  An updated counseling framework for moderate-penetrance colorectal cancer susceptibility genes.
  Kelsey E Breen, Bryson W Katona, Amanda Catchings, Megha Ranganathan, Vanessa Marcell, Alicia Latham, Matthew B Yurgelun, Zsofia K Stadler> ;Genetics in Medicine. 2022 Dec 1
• Preface.
  Douglas A Rubinson, Matthew B Yurgelun> ;Hematology/oncology Clinics of North America. 2022 Oct 1
• Serrated Polyposis Syndrome in a Young Adolescent Patient.
  Victor L Fox, Inbar S Spofford, Brian D Crompton, Mathew B Yurgelun, Craig W Lillehei, Jeffrey D Goldsmith> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 Sep 1
• 1 citations
  The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice.
  Chirayu Mohindroo, Ana De Jesus-Acosta, Matthew B Yurgelun, Anirban Maitra, Maureen Mork, Florencia McAllister> ;Surgical Pathology Clinics. 2022 Sep 1
• 1 citations
  Development and Validation of the PREMMplus Model for Multigene Hereditary Cancer Risk Assessment.
  Matthew B Yurgelun, Hajime Uno, C Sloane Furniss, Chinedu Ukaegbu, Miki Horiguchi, Amal Yussuf, Holly LaDuca, Anu Chittenden, Judy E Garber, Sapna Syngal> ;Journal of Clinical Oncology. 2022 Dec 10
• Building on More Than 20 Years of Progress in Pancreatic Cancer Surveillance for High-Risk Individuals.
  Matthew B Yurgelun> ;Journal of Clinical Oncology. 2022 Oct 1
• 6 citations
  Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program.
  Brittany L Bychkovsky, Tianyu Li, Jilliane Sotelo, Nabihah Tayob, Joanna Mercado, Israel Gomy, Anu Chittenden, Sarah Kane, Samantha Stokes, Melissa E Hughes, Ji Seok K...> ;Clinical Cancer Research. 2022 Jun 1
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Journal Articles

• Germline Cancer Susceptibility Gene Variants, Somatic Second Hits, and Survival Outcomes in Patients with Resected Pancreatic Cancer  
  Richard F Dunne, Leona A Doyle, William C Hahn, Jason L Hornick, Andrea J Bullock, Sapna Syngal, Albert C Koong, Natalia Khalaf, Brian M Wolpin, Douglas A Rubinson, Da..., Nature
• Validation of a Targeted Next-Generation Sequencing Approach to Detect Mismatch Repair Deficiency in Colorectal Adenocarcinoma  
  Lynette M Sholl, Amitabh Srivastava, Neal I Lindeman, Matthew B Yurgelun, Fei Dong, Nature

Lectures

• Implementation of systematic genetic counseling (GC) and multigene germline testing (MGT) for pancreatic cancer (PC) patients (pts). 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/24/2020
• Improving cascade genetic testing for families with inherited pancreatic cancer (PDAC) risk: The GENetic Education, Risk Assessment and TEsting (GENERATE) study. 
  ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/24/2020
• Improving cascade genetic testing for families with inherited pancreatic cancer (PDAC) risk: The genetic education, risk assessment and testing (GENERATE) study. 
  2019 ASCO Annual Meeting - 6/1/2019
• Lynch Syndrome: Update on Comprehensive Screening and Risk Reduction. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018
• Implementing universal genetic counseling (GC) and multigene germline testing (MGT) for pancreatic cancer (PC) patients (pts). 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/2/2018
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