RachelAnnFreedmanMDMPH

Breast Cancer

Associate Professor of Medicine, Harvard Medical School; Medical Director of the Dana-Farber Cancer Care Collaborative, Medical Oncologist, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute; Clinical Researcher

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Office
450 Brookline Ave
Boston, MA 02215
Phone+1 617-632-3800
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Summary

Dr. Rachel Freedman is an oncologist in Boston, MA and is affiliated with multiple hospitals in the area, including Brigham and Women's Hospital, Massachusetts General Hospital, North Shore Medical Center, Dana-Farber Cancer Institute, and Brigham and Women's Faulkner Hospital. She received her medical degree from Georgetown University School of Medicine and has been in practice 14 years. She specializes in breast cancer and hematologic oncology and is experienced in breast cancer, geriatrics, healthcare disparities, health services accessibility, and general medical oncology.

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2006 - 2009
Harvard School of Public HealthMPH, Clinical Effectiveness, 2007 - 2008
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 2003 - 2006
Georgetown University School of MedicineClass of 2003

Certifications & Licensure

FL State Medical License 2022 - Present
NH State Medical License 2023 - 2025
ME State Medical License 2022 - 2025
VT State Medical License 2022 - 2024
CT State Medical License 2022 - 2024
RI State Medical License 2022 - 2024
OH State Medical License 2022 - 2024
MA State Medical License 2005 - 2024
American Board of Internal Medicine Medical Oncology
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Clinical Trials

The Hurria Older PatiEnts (HOPE) With Breast Cancer Study Start of enrollment: 2011 Sep 09
Active, not recruiting
HKI-272 for HER2-Positive Breast Cancer and Brain Metastases Start of enrollment: 2012 Feb 01
Active, not recruiting
Phase 2
Neratinib +/- Fulvestrant in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer Start of enrollment: 2012 Dec 11
Completed
Phase 2
Phase II Study of Eribulin Mesylate, Trastuzumab, and Pertuzumab in Women With Metastatic, Unresectable Locally Advanced, or Locally Recurrent HER2-Positive Breast Cancer Start of enrollment: 2013 Sep 01
Terminated
Phase 2
Trastuzumab Emtansine in Treating Older Patients With Human Epidermal Growth Factor Receptor 2-Positive Stage I-III Breast Cancer Start of enrollment: 2015 May 01
Novel Social Media Intervention For Older Br CA Patients Start of enrollment: 2016 Feb 08
Completed
Not Applicable
ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer Start of enrollment: 2018 Aug 22
Active, not recruiting
Phase 2
Elevate! : An Elderly Breast Cancer Cohort Study Start of enrollment: 2019 Feb 19
Recruiting
'ADVANCE' (A Pilot Trial) Start of enrollment: 2019 Mar 21
Active, not recruiting
Phase 1
Individualizing Surveillance Mammography for Older Breast Cancer Survivors Start of enrollment: 2019 May 16
Completed
Not Applicable
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Publications & Presentations

PubMed

Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospe...
Mina S Sedrak, Can-Lan Sun, Marie Bae, Rachel A Freedman, Allison Magnuson, Tracey O'Connor, Beverly Moy, Tanya M Wildes, Heidi D Klepin, Andrew E Chapman, William P T...> ;Journal of Cancer Survivorship. 2024 Apr 28
Prognosis and treatment outcomes for patients with stage IA triple-negative breast cancer.
Julieta Leone, Carlos T Vallejo, Olga Martínez-Sáez, Nabihah Tayob, Paolo Tarantino, Rachel A Freedman, Adrienne G Waks, Ana Garrido-Castro, Filipa Lynce, Nancy U Lin,...> ;NPJ Breast Cancer. 2024 Apr 4
Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer.
Julieta Leone, Michael J Hassett, Rachel A Freedman, Sara M Tolaney, Noah Graham, Nabihah Tayob, Carlos T Vallejo, Eric P Winer, Nancy U Lin, José P Leone> ;JAMA Oncology. 2024 Apr 1
ASO Visual Abstract: Trends in Locoregional Therapy in Older Women with Early-Stage Hormone Receptor-Positive Breast Cancer by Frailty and Life Expectancy.
Christina A Minami, Ginger Jin, Rachel A Freedman, Mara A Schonberg, Tari A King, Elizabeth A Mittendorf> ;Annals of Surgical Oncology. 2024 Feb 1
Falls prechemotherapy and toxicity-related hospitalization during adjuvant chemotherapy for breast cancer in older women: Results from the prospective multicenter HOPE...
Jingran Ji, Marie Bae, Can-Lan Sun, Tanya M Wildes, Rachel A Freedman, Allison Magnuson, Tracey O'Connor, Beverly Moy, Heidi D Klepin, Andrew E Chapman, William P Tew,...> ;Cancer. 2024 Mar 15
1 citations
Trends in Locoregional Therapy in Older Women with Early-Stage Hormone Receptor-Positive Breast Cancer by Frailty and Life Expectancy.
Christina A Minami, Ginger Jin, Rachel A Freedman, Mara A Schonberg, Tari A King, Elizabeth A Mittendorf> ;Annals of Surgical Oncology. 2024 Feb 1
Racial and Ethnic Disparities in Outcomes After Breast-Conserving Therapy and Endocrine Therapy for DCIS: A Post-Hoc Analysis of the NSABP B-35 Randomized Clinical Trial.
Olga Kantor, Tari A King, Alyssa Jones, Charity Glass, Saskia J Leonard, Esther R Ogayo, Erica L Mayer, Mariana Chavez-MacGregor, Lisa A Newman, Rachel A Freedman, Eli...> ;Annals of Surgical Oncology. 2023 Dec 1
ASO Visual Abstract: Racial Disparities in Locoregional Recurrence in Postmenopausal Patients with Stage I-III, Hormone Receptor-Positive Breast Cancer Enrolled in the...
Charity C Glass, Robert M Pride, Rachel A Freedman, Erica L Mayer, Esther R Ogayo, Mariana Chavez-MacGregor, Tari A King, Elizabeth A Mittendorf, Olga Kantor> ;Annals of Surgical Oncology. 2024 Jan 1
Racial Disparities in Locoregional Recurrence in Postmenopausal Patients with Stage I-III, Hormone Receptor-Positive Breast Cancer Enrolled in the NSABP B-42 Clinical ...
Charity C Glass, Robert M Pride, Rachel A Freedman, Erica L Mayer, Esther R Ogayo, Mariana Chavez-MacGregor, Tari A King, Elizabeth A Mittendorf, Olga Kantor> ;Annals of Surgical Oncology. 2023 Dec 1
1 citations
Inequities in referrals to a breast cancer risk assessment and prevention clinic: a mixed methods study.
Claire B King, Brittany L Bychkovsky, Erica T Warner, Tari A King, Rachel A Freedman, Elizabeth A Mittendorf, Fisher Katlin, Anna Revette, Danielle M Crookes, Neil Man...> ;BMC Primary Care. 2023 Aug 25
Estimating mortality in women with triple-negative breast cancer: The 'ESTIMATE triple-negative' tool.
José P Leone, Noah Graham, Julieta Leone, Sara M Tolaney, Bernardo A Leone, Rachel A Freedman, Michael J Hassett, Carlos T Vallejo, Eric P Winer, Nancy U Lin, Nabihah ...> ;European Journal of Cancer. 2023 Aug 1
Identifying Patterns and Barriers in OncotypeDX Recurrence Score Testing in Older Patients With Early-Stage, Estrogen Receptor-Positive Breast Cancer: Implications for...
Dario Trapani, Qingchun Jin, Caroline C Block, Rachel A Freedman, Nancy U Lin, Elizabeth A Mittendorf, Tari A King, Susan C Lester, Jane E Brock, Nabihah Tayob, Craig ...> ;JCO Oncology Practice. 2023 Aug 1
Breast cancer treatment receipt and the role of financial stress, health literacy, and numeracy among diverse breast cancer survivors.
Ashley Odai-Afotey, Ruth I Lederman, Naomi Y Ko, Haley Gagnon, Tsion Fikre, Daniel A Gundersen, Anna C Revette, Dawn L Hershman, Katherine D Crew, Nancy L Keating, Rac...> ;Breast Cancer Research and Treatment. 2023 Jul 1
8 citations
Racial and Ethnic Disparities in Locoregional Recurrence Among Patients With Hormone Receptor-Positive, Node-Negative Breast Cancer: A Post Hoc Analysis of the TAILORx...
Olga Kantor, Tari A King, Rachel A Freedman, Erica L Mayer, Mariana Chavez-MacGregor, Larissa A Korde, Joseph A Sparano, Elizabeth A Mittendorf> ;JAMA Surgery. 2023 Jun 1
5 citations
Association of Surgery With Frailty Status in Older Women With Early-Stage Breast Cancer.
Christina A Minami, Ginger Jin, Rachel A Freedman, Mara A Schonberg, Tari A King, Elizabeth A Mittendorf> ;JAMA Surgery. 2023 Jun 1
2 citations
Survival in male breast cancer over the past 3 decades.
José P Leone, Rachel A Freedman, Julieta Leone, Sara M Tolaney, Carlos T Vallejo, Bernardo A Leone, Eric P Winer, Nancy U Lin, Michael J Hassett> ;Journal of the National Cancer Institute. 2023 Apr 11
Infrastructure to Support Accrual of Older Adults to National Cancer Institute Clinical Trials.
Gretchen Kimmick, Mina S Sedrak, Grant Williams, Nadine J McCleary, Ashley E Rosko, Jeffrey L Berenberg, Rachel A Freedman, Mary Lou Smith, Amina Ahmed, Hyman B Muss, ...> ;Journal of the National Cancer Institute. Monographs. 2022 Dec 15
5 citations
Low-Intensity Adjuvant Chemotherapy for Breast Cancer in Older Women: Results From the Prospective Multicenter HOPE Trial.
Mina S Sedrak, Can-Lan Sun, Jingran Ji, Harvey J Cohen, Cary P Gross, William P Tew, Heidi D Klepin, Tanya M Wildes, Efrat Dotan, Rachel A Freedman, Tracey O'Connor, S...> ;Journal of Clinical Oncology. 2023 Jan 10
4 citations
Treatment discontinuation, patient-reported toxicities and quality-of-life by age following trastuzumab emtansine or paclitaxel/trastuzumab (ATEMPT).
Tal Sella, Yue Zheng, Nabihah Tayob, Kathryn J Ruddy, Rachel A Freedman, Chau Dang, Denise Yardley, Steven J Isakoff, Vicente Valero, Michelle DeMeo, Harold J Burstein...> ;NPJ Breast Cancer. 2022 Nov 30
1 citations
Breast cancer knowledge and understanding treatment rationales among diverse breast cancer survivors.
Rachel A Freedman, Naomi Y Ko, Ruth I Lederman, Haley Gagnon, Tsion Fikre, Daniel A Gundersen, Anna C Revette, Ashley Odai-Afotey, Olga Kantor, Dawn L Hershman, Kather...> ;Breast Cancer Research and Treatment. 2022 Dec 1
1 citations
'ADVANCE' (a pilot trial) ADjuVANt chemotherapy in the elderly: Developing and evaluating lower-toxicity chemotherapy options for older patients with breast cancer.
Rachel A Freedman, Tianyu Li, Mina S Sedrak, Judith O Hopkins, Nabihah Tayob, Meredith G Faggen, Natalie F Sinclair, Wendy Y Chen, Heather A Parsons, Erica L Mayer, Pa...> ;Journal of Geriatric Oncology. 2023 Jan 1
1 citations
Acceptability of a companion patient guide to support expert consensus guidelines on surveillance mammography in older breast cancer survivors.
Rachel A Freedman, Anna C Revette, Haley Gagnon, Adriana Perilla-Glen, Molly Kokoski, Saida O Hussein, Erin Leone, Nicole Hixon, Rebeka Lovato, Wendy Loeser, Nancy U L...> ;Breast Cancer Research and Treatment. 2022 Sep 1
1 citations
Surveillance mammography after treatment for male breast cancer.
Siddhartha Yadav, Lindsey Sangaralingham, Stephanie R Payne, Karthik V Giridhar, Tina J Hieken, Judy C Boughey, Robert W Mutter, John R Hawse, Rafael E Jimenez, Rachel...> ;Breast Cancer Research and Treatment. 2022 Aug 1
4 citations
Assessment of Oncologists' Perspectives on Omission of Sentinel Lymph Node Biopsy in Women 70 Years and Older With Early-Stage Hormone Receptor-Positive Breast Cancer.
Christina A Minami, Ava F Bryan, Rachel A Freedman, Anna C Revette, Mara A Schonberg, Tari A King, Elizabeth A Mittendorf> ;JAMA Network Open. 2022 Aug 1
Surveillance mammography in older breast cancer survivors: Current practice patterns and patient perceptions.
Dhauna Karam, Robert A Vierkant, Shawna Ehlers, Rachel A Freedman, Jessica Austin, Sadia Khanani, Nicole L Larson, Charles L Loprinzi, Fergus Couch, Janet E Olson, Kat...> ;Journal of Geriatric Oncology. 2022 Sep 1
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Journal Articles

Functional Decline and Resilience in Older Women Receiving Adjuvant Chemotherapy for Breast Cancer
Aminah Jatoi, Antonio C Wolff, Harvey Jay Cohen, Rachel A Freedman, Gustav Magrinat, Julie Gralow, Gretchen Kimmick, Heidi D Klepin, Harold Burstein, Hyman Muss, Jeann..., Journal of the American Geriatrics Society

Press Mentions

‘Real Housewives of Miami’ Star Guerdy Abraira Reveals Breast Cancer DiagnosisMay 10th, 2023
Lime in Chelsea Set to Participate in Bakes for Breast CancerMay 4th, 2023
Black Women Should Start Breast Cancer Screening at Younger Age, Study SuggestsApril 28th, 2023
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