MikeYChenMD

Brain & Spinal Tumor

Physician

Overview of Dr. Chen

Dr. Mike Chen is a neurosurgeon in Duarte, CA and is affiliated with multiple hospitals in the area, including City of Hope Comprehensive Cancer Center and Huntington Health. He received his medical degree from Sidney Kimmel Medical College at Thomas Jefferson University and has been in practice 21 years. He is one of 6 doctors at City of Hope Comprehensive Cancer Center and one of 11 doctors at Huntington Health who specialize in Neurosurgery. He has more than 40 publications and over 500 citings.

Office
Division of Neurosurgery
1500 East Duarte Road
Duarte, CA 91010
Book by Phone+1(415) 630-4266

Fax+1 626-471-7344
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Education & Training

Virginia Commonwealth University Health SystemResidency, Neurological Surgery, 2000 - 2006
Johns Hopkins University School of MedicineInternship, Transitional Year, 1996 - 1997
Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1996

Certifications & Licensure

CA State Medical License 2006 - 2026
VA State Medical License 2000 - 2024
MD State Medical License 1998 - 2023
American Board of Neurological Surgery Neurological Surgery

Publications & Presentations

PubMed

Author Correction: Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Brenda Aguilar, Jamie R Wagner, Jinny A Paul,...> ;Nature Medicine. 2024 Mar 21
Retraction Note: Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain.
Arunoday Bhan, Khairul Ansari, Mike Y Chen, Rahul Jandial> ;Scientific Reports. 2024 Mar 12
1 citations
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial.
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Brenda Aguilar, Jamie R Wagner, Jinny A Paul,...> ;Nature Medicine. 2024 Mar 7
3 citations
In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells.
Mike Y Chen, Jing Li, Nianli Zhang, Erik I Waldorff, James T Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang> ;Technology in Cancer Research & Treatment. 2022 Sep 29
5 citations
Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain.
Arunoday Bhan, Khairul Ansari, Mike Y. Chen, Rahul Jandial> ;Scientific Reports. 2021 Oct 15
10 citations
Inhibition of Jumonji Histone Demethylases Selectively Suppresses HER2+ Breast Leptomeningeal Carcinomatosis Growth via Inhibition of GMCSF Expression.
Arunoday Bhan, Khairul I. Ansari, Mike Y. Chen, Rahul Jandial> ;Cancer Research. 2021 Jun 15
3 citations
Utility of Preoperative Blood-Oxygen-Level-Dependent Functional MR Imaging in Patients with a Central Nervous System Neoplasm.
Ammar Chaudhry, Sohaib Naim, Maryam Gul, Abbas Chaudhry, Mike Y. Chen, Rahul Jandial, Behnam Badie> ;Neuroimaging Clinics of North America. 2021 Feb 1
24 citations
MMR Vaccination: A Potential Strategy to Reduce Severity and Mortality of COVID-19 Illness.
J. Wesson Ashford, Jeffrey E. Gold, Mary Jane A. Huenergardt, Ronit B.A. Katz, Susanne E. Strand, Joe Bolanos, Christopher J. Wheeler, George Perry, Carr J Smith, Lawr...> ;The American Journal of Medicine. 2021 Feb 1
16 citations
Upregulated CBX8 Promotes Cancer Metastasis via the WNK2/MMP2 Pathway.
Yongsheng Jia, Yujun Wang, Cuicui Zhang, Mike Yue Chen> ;Molecular Therapy Oncolytics. 2020 Oct 4
11 citations
Astrocytic IGFBP2 and CHI3L1 in cerebrospinal fluid drive cortical metastasis of HER2+breast cancer
Khairul I. Ansari, Arunoday Bhan, Xueli Liu, Mike Y. Chen, Rahul Jandial> ;Clinical & Experimental Metastasis. 2020 Apr 11
6 citations
Utility of Preoperative Blood-Oxygen-Level–Dependent Functional MR Imaging in Patients with a Central Nervous System Neoplasm
Ammar Chaudhry, Sohaib Naim, Maryam Gul, Abbas Chaudhry, Mike Y. Chen, Rahul Jandial, Behnam Badie> ;Radiologic Clinics of North America. 2019 Nov 1
31 citations
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer
Houliang Deng, Xiaowen Guan, Longcai Gong, Jianming Zeng, Hongjie Zhang, Mike Y. Chen, Gang Li> ;Scientific Reports. 2019 Jan 17
21 citations
Inhibition of GLO1 in Glioblastoma Multiforme Increases DNA-AGEs, Stimulates RAGE Expression, and Inhibits Brain Tumor Growth in Orthotopic Mouse Models
Rahul Jandial, Josh Neman, Punnajit Lim, Daniel Tamae, Claudia M. Kowolik, Gerald E. Wuenschell, Sarah C. Shuck, Alexandra K Ciminera, Luis R. De Jesus, Ching Ouyang, ...> ;International Journal of Molecular Sciences. 2018 Jan 30
27 citations
Astrocyte-induced Reelin expression drives proliferation of Her2+ breast cancer metastases
Rahul Jandial, Cecilia Choy, Danielle M Levy, Mike Y. Chen, Khairul I. Ansari> ;Clinical & Experimental Metastasis. 2017 Feb 17
96 citations
Neural Stem Cell–Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients
Jana Portnow, Timothy W. Synold, Behnam Badie, Revathiswari Tirughana, Simon F. Lacey, Massimo D'Apuzzo, Marianne Z. Metz, Joseph Najbauer, Victoria Bedell, Tien Vo, M...> ;Clinical Cancer Research. 2017 Jun 15
1 citations
Chronic Leptomeningitis and Spinal Intradural Mass Secondary to Alternaria Infection in a Patient with Ventriculoperitoneal Shunt
Sanjeet Dadwal, Russell E. Thompson, Rahul Jandial, Bernard Tegtmeier, Mike Yue Chen> ;Case Reports in Infectious Diseases. 2016 Oct 20
3 citations
Convection-enhanced delivery of sorafenib and suppression of tumor progression in a murine model of brain melanoma through the inhibition of signal transducer and acti...
Zhaoxia Zou, Yufang Yin, Jenny Lin, Li-chen J. Hsu, Vanessa L. Brandon, Fan Yang, Richard Jove, Rahul Jandial, Gang Li, Mike Y. Chen> ;Journal of Neurosurgery. 2016 May 1
12 citations
Influence of Hormone Receptor Status on Spinal Metastatic Lesions in Patients with Breast Cancer.
Jenny Lin, Leanne Goldstein, Amanda Nesbit, Mike Y. Chen> ;World Neurosurgery. 2016 Jan 1
24 citations
Current and emerging treatments for brain metastases.
Jenny Lin, Rahul Jandial, Amanda Nesbit, Behnam Badie, Mike Y. Chen> ;Oncology. 2015 Apr 15
1 citations
Therapeutic disruption of the blood brain barrier in metastasis.
Rahul Jandial, Josh Neman, Mike Y. Chen> ;Neurosurgery. 2014 Apr 1
18 citations
A pilot microdialysis study in brain tumor patients to assess changes in intracerebral cytokine levels after craniotomy and in response to treatment with a targeted an...
Jana Portnow, Behnam Badie, Xueli Liu, Paul Frankel, Shu Mi, Mike Y. Chen, Timothy W. Synold> ;Journal of Neuro-Oncology. 2014 Mar 15
74 citations
Altered expression of polycomb group genes in glioblastoma multiforme.
Gang Li, Charles Warden, Zhaoxia Zou, Josh Neman, Joseph S. Krueger, Alisha Jain, Rahul Jandial, Mike Y. Chen> ;Plos One. 2013 Nov 15
29 citations
Posterior-only approach for lumbar vertebral column resection and expandable cage reconstruction for spinal metastases.
Rahul Jandial, Brandon Kelly, Mike Yue Chen> ;Journal of Neurosurgery. Spine. 2013 Jul 1
1 citations
Neuroanatomy changes with repetitive mild head injury in athletes.
Rahul Jandial, Matthew J. Duenas, Mike Y. Chen> ;Neurosurgery. 2013 Jun 1
Heterogeneous cellular origins for glioma in murine model.
Rahul Jandial, Mike Y. Chen> ;Neurosurgery. 2013 Apr 1
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Press Mentions

Brain Mapping Foundation Tackles COVID-19 Pandemic Through Science, Technology, Innovation, and Policy Endorsing California Proposition 14-2020September 16th, 2020
30 Cancer Symptoms You Should Never IgnoreOctober 31st, 2019
Globus Medical Launches FORTIFY Variable Angle Expandable Corpectomy Spacer SystemApril 15th, 2019
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