MiriamKLauferMD

Pediatric Infectious Disease • Baltimore, MD

Associate Professor, Pediatrics, University of Maryland School of Medicine

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Office
22 S Greene St
N5w40
Baltimore, MD 21201
Phone+1 410-328-6749

Fax+1 410-328-6136
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Education & Training

Johns Hopkins UniversityFellowship, Pediatric Infectious Diseases, 2001 - 2004
Perelman School of Medicine at the University of PennsylvaniaClass of 1997

Certifications & Licensure

MD State Medical License 2004 - 2024
NY State Medical License 1998 - 2000

Clinical Trials

Chloroquine for Malaria in Pregnancy Start of enrollment: 2012 Feb 01
Completed
Phase 3
Daily Trimethoprim-sulfamethoxazole or Weekly Chloroquine Among Adults on ART in Malawi Start of enrollment: 2012 Nov 01
Completed
Not Applicable

Publications & Presentations

PubMed

Malaria prevention: advancing clinical trials to policy.
Mungwira, R., Divala, T., Laufer, M.> ;The Lancet. Infectious Diseases. 2024 Jan 12
Plasmodium falciparum infection and disease in infancy associated with increased risk of malaria and anaemia in childhood.
Liana R Andronescu, Andrea G Buchwald, Ankur Sharma, Andy Bauleni, Patricia Mawindo, Yuanyuan Liang, Julie R Gutman, Don P Mathanga, Jobiba Chinkhumba, Miriam K Laufer> ;Malaria Journal. 2023 Jul 26
Artemether-lumefantrine efficacy among adults on antiretroviral therapy in Malawi.
Wongani Nyangulu, Randy G Mungwira, Titus H Divala, Nginache Nampota-Nkomba, Osward M Nyirenda, Andrea G Buchwald, Jernelle Miller, Dominique E Earland, Matthew Adams,...> ;Malaria Journal. 2023 Jan 27
1 citations
The Association among Malaria in Pregnancy, Neonatal inflammation, and Neurocognitive Development in a Cohort of Malawian Infants.
Andrea G Buchwald, Sarah Boudova, Ingrid Peterson, Titus Divala, Randy Mungwira, Patricia Mawindo, Melissa Gladstone, Cristiana Cairo, Miriam K Laufer> ;The American Journal of Tropical Medicine and Hygiene. 2022 Nov 14
1 citations
The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-a...
George Mtove, Daniel T R Minja, Omari Abdul, Samwel Gesase, Kenneth Maleta, Titus H Divala, Noel Patson, Ulla Ashorn, Miriam K Laufer, Mwayiwawo Madanitsa, Per Ashorn,...> ;Malaria Journal. 2022 Oct 12
3 citations
Understanding the Intransigence of Malaria in Malawi.
Lauren M Cohee, Jessy Goupeyou-Youmsi, Karl B Seydel, Charles Mangani, Peter Ntenda, Alick Sixpence, Rex B Mbewe, Alfred Matengeni, Shannon Takala-Harrison, Edward D W...> ;The American Journal of Tropical Medicine and Hygiene. 2022 Oct 11
Isoniazid preventive therapy-related adverse events among Malawian adults on antiretroviral therapy: A cohort study.
Lufina Tsirizani-Galileya, Elasma Milanzi, Randy Mungwira, Titus Divala, Jane Mallewa, Donnie Mategula, Nginache Nampota, Victor Mwapasa, Andrea Buchwald, Matthew B La...> ;Medicine. 2022 Sep 30
6 citations
Dynamics of the Gut Microbiome in-Infected Children during the First Two Years of Life.
Esther Ndungo, Johanna B Holm, Syze Gama, Andrea G Buchwald, Sharon M Tennant, Miriam K Laufer, Marcela F Pasetti, David A Rasko> ;Msystems. 2022 Oct 26
3 citations
Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Acquisition Is Associated With Individual Exposure but Not Community-Level Transmission.
DeAnna J Friedman-Klabanoff, Meagan C Fitzpatrick, Meagan E Deming, Vaidehi Agrawal, Sandra Sitar, Torin Schaafsma, Elizabeth Brown, Kathleen M Neuzil, Ruanne V Barnab...> ;The Journal of Infectious Diseases. 2022 Aug 24
1 citations
High burden of malaria among Malawian adults on antiretroviral therapy after discontinuing prophylaxis.
Randy G Mungwira, Matthew B Laurens, Wongani Nyangulu, Titus H Divala, Nginache Nampota-Nkomba, Andrea G Buchwald, Osward M Nyirenda, Edson Mwinjiwa, Maxwell Kanjala, ...> ;AIDS. 2022 Oct 1
2 citations
RTS,S today and tomorrow's science.
Nginache Nampota Nkomba, Cristiana Cairo, Miriam K Laufer> ;Cell Host & Microbe. 2022 May 11
School-Based Malaria Screening and Treatment Reduces Plasmodium falciparum Infection and Anemia Prevalence in Two Transmission Settings in Malawi.
Lauren M Cohee, Ingrid Peterson, Andrea G Buchwald, Jenna E Coalson, Clarissa Valim, Moses Chilombe, Andrew Ngwira, Andy Bauleni, Sarah Schaffer-DeRoo, Karl B Seydel, ...> ;The Journal of Infectious Diseases. 2022 Aug 12
5 citations
Blood-feeding patterns of Anopheles vectors of human malaria in Malawi: implications for malaria transmission and effectiveness of LLIN interventions.
Rex B Mbewe, John B Keven, Themba Mzilahowa, Don Mathanga, Mark Wilson, Lauren Cohee, Miriam K Laufer, Edward D Walker> ;Malaria Journal. 2022 Mar 3
Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study.
Anna Bershteyn, Angela M Dahl, Tracy Q Dong, Meagan E Deming, Connie L Celum, Helen Y Chu, Angelica C Kottkamp, Alexander L Greninger, Risa M Hoffman, Keith R Jerome, ...> ;Clinical Infectious Diseases. 2022 Aug 24
Comparison of statistical methods for the analysis of recurrent adverse events in the presence of non-proportional hazards and unobserved heterogeneity: a simulation s...
Noel Patson, Mavuto Mukaka, Lawrence Kazembe, Marinus J C Eijkemans, Don Mathanga, Miriam K Laufer, Tobias Chirwa> ;BMC Medical Research Methodology. 2022 Jan 20
Effect of adverse events on non-adherence and study non-completion in malaria chemoprevention during pregnancy trial: A nested case control study.
Noel Patson, Mavuto Mukaka, Ingrid Peterson, Titus Divala, Lawrence Kazembe, Don Mathanga, Miriam K Laufer, Tobias Chirwa> ;Plos One. 2022 Jan 1
Reply to Ramirez and Diaz-Quijano.
Matthew B. Laurens, Matthew Downs, Miriam K. Laufer> ;Clinical Infectious Diseases. 2021 Oct 20
1 citations
Joint modelling of multivariate longitudinal clinical laboratory safety outcomes, concomitant medication and clinical adverse events: application to artemisinin-based ...
Noel Patson, Mavuto Mukaka, Umberto D'Alessandro, Gertrude Chapotera, Victor Mwapasa, Don P. Mathanga, Lawrence N. Kazembe, Miriam K. Laufer, Tobias Chirwa> ;BMC Medical Research Methodology. 2021 Oct 9
8 citations
Revisiting Co-trimoxazole Prophylaxis for African Adults in the Era of Antiretroviral Therapy: A Randomized Controlled Clinical Trial.
Matthew B. Laurens, Randy G. Mungwira, Nginache Nampota, Osward M. Nyirenda, Titus H. Divala, Maxwell Kanjala, Felix A. Mkandawire, Lufina Tsirizani Galileya, Wongani ...> ;Clinical Infectious Diseases. 2021 Sep 15
2 citations
The effect of intermittent preventive treatment of malaria during pregnancy and placental malaria on infant risk of malaria.
Liana R. Andronescu, Ankur Markand Sharma, Ingrid Peterson, Martin Kachingwe, Witness Kachepa, Yuanyuan Liang, Julie Gutman, Don P. Mathanga, Jobiba Chinkhumba, Miriam...> ;The Journal of Infectious Diseases. 2021 Jul 3
5 citations
Whole-genome analysis of Malawian Plasmodium falciparum isolates identifies possible targets of allele-specific immunity to clinical malaria.
Zalak Shah, Myo T. Naung, Kara A. Moser, Matthew Adams, Andrea G. Buchwald, Ankit Dwivedi, Amed Ouattara, Karl B. Seydel, Don P. Mathanga, Alyssa E. Barry, David Serre...> ;Plos Genetics. 2021 May 25
4 citations
Overdiagnosis of Malaria Illness in an Endemic Setting: A Facility-Based Surveillance Study in Malawi
Ingrid Peterson, Atupele Kapito-Tembo, Andrew Bauleni, Osward M. Nyirenda, Paul Pensulo, William Still, Clarissa Valim, Lauren M. Cohee, Terrie E. Taylor, Don P. Matha...> ;The American Journal of Tropical Medicine and Hygiene. 2021 May 3
11 citations
School-based screening and treatment may reduce P. falciparum transmission.
Lauren M. Cohee, Clarissa Valim, Jenna E. Coalson, Andrew Nyambalo, Moses Chilombe, Andrew Ngwira, Andy Bauleni, Karl B. Seydel, Mark L. Wilson, Terrie E. Taylor, Don ...> ;Scientific Reports. 2021 Mar 25
6 citations
Population Attributable Fraction of Anemia Associated with P. falciparum Infection in Children in Southern Malawi
Doris P. Yimgang, Andrea G. Buchwald, Jenna E. Coalson, Jenny A. Walldorf, Andy Bauleni, Atupele Kapito-Tembo, Don P. Mathanga, Terrie E. Taylor, Miriam K. Laufer, Lau...> ;The American Journal of Tropical Medicine and Hygiene. 2021 Mar 3
4 citations
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy.
Haoting Hsu, Sarah Boudova, Godfrey Mvula, Titus H. Divala, David Rach, Randy G. Mungwira, Francesca Boldrin, Giulia Degiacomi, Riccardo Manganelli, Miriam K. Laufer, ...> ;Cellular Immunology. 2021 Jan 1
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Journal Articles

Oxford University Press Has Registered This DOI Pre-Publication
Sarah Hochman, Terrie E Taylor, Miriam K Laufer, John D Sorkin, Oxford University Press

Other

Antimalarial drugs: An overview
Laufer MK, Travassos M
http://www.uptodate.com/contents/antimalarial-drugs-an-overview
UpToDate, Wolters Kluwer Health - 2012-06-26

Press Mentions

A Three-Dose Malaria Vaccine Shows Safety, Efficacy in West African AdultsDecember 22nd, 2022
Three University of Maryland School of Medicine Faculty Members Honored by Baltimore Business JournalNovember 1st, 2022
NIH Grant Expands Global Health ResearchJune 3rd, 2022
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Grant Support

Clinical Trial Of Trimethoprim-Sulfamethoxazole Or Chloroquine In Adults On ARTNational Institute Of Allergy And Infectious Diseases2011
Epidemiology Of Malaria In Malawi: Human Hosts And Parasites In Three DistrictsNational Institute Of Allergy And Infectious Diseases2010–2011
Clinical Trial Of Chloroquine Weekly Or As IPT To Prevent Malaria In Pregnancy InNational Institute Of Allergy And Infectious Diseases2010–2011
A Randomized, Controlled Clinical Trial Of Chloroquine As Chemoprophylaxis VersusNational Institute Of Allergy And Infectious Diseases2008
Molecular Epidemiology Of Drug Resistant MalariaNational Institute Of Allergy And Infectious Diseases2004–2008

Hospital Affiliations

University of Maryland Medical CenterBaltimore, Maryland