NathanSinghMD

PubMed

• 2 citations
  Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th-December 1st, 2022).
  Paolo A Ascierto, Antonio Avallone, Carlo Bifulco, Sergio Bracarda, Joshua D Brody, Leisha A Emens, Robert L Ferris, Silvia C Formenti, Omid Hamid, Douglas B Johnson, ...> ;Journal of Translational Medicine. 2023 Jul 20
• 2 citations
  Inducing T cell dysfunction by chronic stimulation of CAR-engineered T cells targeting cancer cells in suspension cultures.
  Mehmet Emrah Selli, Jack H Landmann, Corvin Arveseth, Nathan Singh> ;STAR Protocols. 2023 Mar 17
• 1 citations
  Discovery of a novel genomic alteration that renders leukemic cells resistant to CD19-targeted immunotherapies.
  Armin Ghobadi, Jack H Landmann, Alun Carter, Matthew L Cooper, Mehmet Emrah Selli, Jufang Chang, Matthew Baker, Christopher A Miller, Francesca Ferraro, David Y Chen, ...> ;Blood Advances. 2022 Oct 25
• 16 citations
  Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.
  Amanda Heard, Jack H Landmann, Ava R Hansen, Alkmini Papadopolou, Yu-Sung Hsu, Mehmet Emrah Selli, John M Warrington, John Lattin, Jufang Chang, Helen Ha, Martina Haug...> ;Nature Communications. 2022 Jun 11
• 129 citations
  An NK-like CAR T cell transition in CAR T cell dysfunction.
  Charly R. Good, M. Angela Aznar, Shunichiro Kuramitsu, Parisa Samareh, Sangya Agarwal, Greg Donahue, Kenichi Ishiyama, Nils Wellhausen, Austin K. Rennels, Yujie Ma, Li...> ;Cell. 2021 Dec 2
• 4 citations
  Advances in CAR design.
  Amanda Heard, Jufang Chang, John M. Warrington, Nathan Singh> ;Best Practice & Research. Clinical Haematology. 2021 Sep 1
• 76 citations
  Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells
  Nathan Singh, Noelle V. Frey, Boris Engels, David M. Barrett, Olga Shestova, Pranali Ravikumar, Katherine D. Cummins, Yong Gu Lee, Raymone Pajarillo, Inkook Chun, Amy ...> ;Nature Medicine. 2021 Apr 22
• 24 citations
  Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies
  Sisi Zheng, Elisabeth Gillespie, Ammar S. Naqvi, Katharina E. Hayer, Zhiwei Ang, Manuel Torres-Diz, Mathieu Quesnel-Vallieres, David A Hottman, Asen Bagashev, John Chu...> ;Blood Cancer Discovery. 2021 Jan 1
• 26 citations
  Mechanisms of resistance to CAR T cell therapies
  Nathan Singh, Elena Orlando, Jun Xu, Jie Xu, Zev A. Binder, McKensie A. Collins, Donald M. O'Rourke, J. Joseph Melenhorst> ;Seminars in Cancer Biology. 2020 Oct 1
• 150 citations
  Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction
  Nathan Singh, Yong Gu Lee, Olga Shestova, Pranali Ravikumar, Katharina E. Hayer, Seok Jae Hong, Xueqing Maggie Lu, Raymone Pajarillo, Sangya Agarwal, Shunichiro Kurami...> ;Cancer Discovery. 2020 Apr 1
• 231 citations
  Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering.
  Margaret M. Billingsley, Nathan Singh, Pranali Ravikumar, Rui Zhang, Carl H. June, Michael J. Mitchell> ;Nano Letters. 2020 Feb 5
• 9 citations
  Boosting engineered T cells
  Nathan Singh, Carl H. June> ;Science. 2019 Jul 12
• 11 citations
  Overview of Hematopoietic Cell Transplantation for the Treatment of Hematologic Malignancies
  Nathan Singh, Alison W. Loren> ;Clinics in Chest Medicine. 2017 Dec 1
• 16 citations
  Erythropoietic protoporphyria in an adult with sequential liver and hematopoietic stem cell transplantation: A case report.
  Annika L. Windon, Rashmi Tondon, Nathan Singh, Samir Abu-Gazala, David L. Porter, J. Eric Russell, Colleen Cook, Elaine Lander, Georgeine Smith, Kim M. Olthoff, Abraha...> ;American Journal of Transplantation. 2018 Mar 1
• 54 citations
  Genome-Editing Technologies in Adoptive T Cell Immunotherapy for Cancer
  Nathan Singh, Junwei Shi, Carl H. June, Marco Ruella> ;Current Hematologic Malignancy Reports. 2017 Oct 16
• 101 citations
  Monocyte lineage–derived IL-6 does not affect chimeric antigen receptor T-cell function
  Nathan Singh, Ted J. Hofmann, Zachary Gershenson, Bruce L. Levine, Stephan A. Grupp, David T. Teachey, David M. Barrett> ;Cytotherapy. 2017 May 11
• Vemurafenib for BRAFV600E-positive metastatic papillary thyroid cancer - Authors' response.
  Marcia S. Brose, Nathan Singh> ;The Lancet. Oncology. 2016 Nov 1
• 4 citations
  Recent advances in engineered T cell therapies targeting B cell malignancies.
  Nathan Singh> ;Discovery Medicine. 2016 Oct 1
• 52 citations
  CAR T Cell Therapy in Acute Lymphoblastic Leukemia and Potential for Chronic Lymphocytic Leukemia
  Nathan Singh, Noelle V. Frey, Stephan A. Grupp, Shannon L. Maude> ;Current Treatment Options in Oncology. 2016 Apr 20
• 196 citations
  Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies.
  Nathan Singh, Jessica Perazzelli, Stephan A. Grupp, David M. Barrett> ;Science Translational Medicine. 2016 Jan 6
• 28 citations
  T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma
  Nathan Singh, Irina Kulikovskaya, David M. Barrett, Gwendolyn Binder-Scholl, Bent K. Jakobsen, Daniel Martinez, Bruce R. Pawel, Carl H. June, Michael Kalos, Stephan A....> ;Oncoimmunology. 2016 Jan 4
• 3 citations
  Donor-derived CD19 chimeric antigen receptor T cells
  Nathan Singh, David M. Barrett> ;Current Opinion in Hematology. 2015 Nov 1
• 4 citations
  Combined B12 and folate deficiency presenting as an aggressive hematologic malignancy
  Nathan Singh, Sohail Qayyum, Mariusz A. Wasik, Selina M. Luger> ;American Journal of Hematology. 2015 Oct 1
• 104 citations
  Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative
  Hans Liebl, Gabby B. Joseph, Michael C. Nevitt, Nathan Singh, Ursula Heilmeier, Karupppasamy Subburaj, Pia M. Jungmann, Charles E. McCulloch, John A. Lynch, Nancy E La...> ;Annals of the Rheumatic Diseases. 2015 Jul 1
• 13 citations
  Roadblocks to success for RNA CARs in solid tumors.
  Nathan Singh, David M. Barrett, Stephan A. Grupp> ;Oncoimmunology. 2014 Dec 2
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Journal Articles

• Genome-Editing Technologies in Adoptive T Cell Immunotherapy for Cancer  
  Nathan Singh, Marco Ruella, Carl H June, Current Hematologic Malignancy Reports