NeilEKayMD

PubMed

• Outpatient treatment with concomitant vaccine-boosted convalescent plasma for patients with immunosuppression and COVID-19.
  Ripoll, J., Juan G Ripoll, Sidna M Tulledge-Scheitel, Anthony A Stephenson, Shane Ford, Marsha L Pike, Ellen K Gorman, Sara N Hanson, Justin E Juskewitch, Alex J Mille...> ;Mbio. 2024 Apr 11
• 3 citations
  CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS.
  R Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Elizabeth L Siegler, James H Girsch, Olivia L Sirpilla, Carli M Stewart, Kun Yun, Ismail Can, Ekene J Ogbodo, ...> ;Blood. 2024 Jan 18
• 7 citations
  Rates Among Hospitalized Patients With COVID-19 Treated With Convalescent Plasma: A Systematic Review and Meta-Analysis.
  Jonathon W Senefeld, Ellen K Gorman, Patrick W Johnson, M Erin Moir, Stephen A Klassen, Rickey E Carter, Nigel S Paneth, David J Sullivan, Olaf H Morkeberg, R Scott Wr...> ;Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 2023 Oct 1
• AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells.
  R Leo Sakemura, Mehrdad Hefazi, Michelle J Cox, Elizabeth L Siegler, Sutapa Sinha, Michael J Hansen, Carli M Stewart, Jennifer M Feigin, Claudia Manriquez Roman, Kenda...> ;Cancer Immunology Research. 2023 Sep 1
• Safety of radiotherapy for second primary malignancies in patients with chronic lymphocytic leukemia receiving concurrent novel agent treatment.
  Samuel R Kosydar, Sameer A Parikh, Scott C Lester, Kari G Rabe, Wei Ding, Jessica F Burlile, Saad S Kenderian, Yucai Wang, Eli Muchtar, Amber B Koehler, Susan M Schwag...> ;American Journal of Hematology. 2023 Nov 1
• Relationship among three common hematological premalignant conditions.
  Nicholas J Boddicker, Sameer A Parikh, Aaron D Norman, Kari G Rabe, Rosalie Griffin, Timothy G Call, Dennis P Robinson, Janet E Olson, Angela Dispenzieri, Vincent Rajk...> ;Leukemia. 2023 Aug 1
• 1 citations
  Functional humoral and cellular response of monovalent COVID-19-vaccines against Omicron BA.2 variant of SARS-CoV-2 in patients with chronic lymphocytic leukemia.
  Matteo Passerini, Tamar Ratishvili, Jonathon M Monroe, Zelalem Temesgen, Thomas E Witzig, Neil E Kay, Richard B Kennedy, Sameer A Parikh> ;Leukemia & Lymphoma. 2023 Apr 1
• 20 citations
  Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.
  Erin M Parry, Ignaty Leshchiner, Romain Guièze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla Lemvigh, Julien Broséus, Sébastien Hergalant, Conor Messer, Fili...> ;Nature Medicine. 2023 Jan 1
• Time to second treatment can be used to predict overall survival in chronic lymphocytic leukemia: identifying risk factors to help guide treatment selection.
  Kurt S Bantilan, Neil E Kay, Sameer A Parikh, Kari G Rabe, Timothy G Call, Jose F Leis, Wei Ding, Susan L Slager, Jacob D Soumerai, Lindsey E Roeker, Anthony Mato, And...> ;Leukemia & Lymphoma. 2023 Feb 1
• 1 citations
  The risk of coronavirus disease 2019 (COVID-19) among individuals with monoclonal B cell lymphocytosis.
  Sameer A Parikh, Sara J Achenbach, Kari G Rabe, Aaron D Norman, Nicholas J Boddicker, Janet E Olson, Timothy G Call, James R Cerhan, Celine M Vachon, Neil E Kay, Esteb...> ;Blood Cancer Journal. 2022 Nov 22
• 14 citations
  Vaccine-boosted convalescent plasma therapy for patients with immunosuppression and COVID-19.
  Juan G Ripoll, Ellen K Gorman, Justin E Juskewitch, Raymund R Razonable, Ravindra Ganesh, Ryan T Hurt, Elitza S Theel, James R Stubbs, Jeffrey L Winters, Sameer A Pari...> ;Blood Advances. 2022 Dec 13
• 3 citations
  Is unmeasurable residual disease (uMRD) the best surrogate endpoint for clinical trials, regulatory approvals and therapy decisions in chronic lymphocytic leukaemia (C...
  Shenmiao Yang, Neil E Kay, Min Shi, Curtis A Hanson, Robert Peter Gale> ;Leukemia. 2022 Nov 1
• 4 citations
  Clinical outcomes in patients with chronic lymphocytic leukemia with disease progression on ibrutinib.
  Paul J Hampel, Kari G Rabe, Timothy G Call, Wei Ding, Jose F Leis, Asher A Chanan-Khan, Saad S Kenderian, Eli Muchtar, Yucai Wang, Sikander Ailawadhi, Amber B Koehler,...> ;Blood Cancer Journal. 2022 Sep 1
• 9 citations
  Progression and survival of MBL: a screening study of 10 139 individuals.
  Susan L Slager, Sameer A Parikh, Sara J Achenbach, Aaron D Norman, Kari G Rabe, Nicholas J Boddicker, Janet E Olson, Geffen Kleinstern, Connie E Lesnick, Timothy G Cal...> ;Blood. 2022 Oct 13
• 6 citations
  Combined ibrutinib and venetoclax for treatment of patients with ibrutinib-resistant or double-refractory chronic lymphocytic leukaemia.
  Paul J Hampel, Kari G Rabe, Timothy G Call, Wei Ding, Jose F Leis, Saad S Kenderian, Eli Muchtar, Yucai Wang, Amber B Koehler, Ricardo Parrondo, Susan M Schwager, Min ...> ;British Journal of Haematology. 2022 Oct 1
• 82 citations
  Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial.
  Tait D Shanafelt, Xin Victoria Wang, Curtis A Hanson, Elisabeth M Paietta, Susan O'Brien, Jacqueline Barrientos, Diane F Jelinek, Esteban Braggio, Jose F Leis, Cong Ch...> ;Blood. 2022 Jul 14
• 22 citations
  CLL update 2022: A continuing evolution in care.
  Neil E Kay, Paul J Hampel, Daniel L Van Dyke, Sameer A Parikh> ;Blood Reviews. 2022 Jul 1
• 2 citations
  B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells.
  Zhiquan Wang, Huihuang Yan, Justin C Boysen, Charla R Secreto, Renee C Tschumper, Dania Ali, Qianqian Guo, Jian Zhong, Jiaqi Zhou, Haiyun Gan, Chuanhe Yu, Diane F Jeli...> ;Blood Cancer Journal. 2022 Jul 1
• 1 citations
  Serum B-Cell maturation antigen is an independent prognostic marker in previously untreated chronic lymphocytic leukemia.
  Camilia M Soof, Tanya M Spektor, Sameer A Parikh, Susan L Slager, Kari G Rabe, Timothy G Call, Saad S Kenderian, Wei Ding, Eli Muchtar, Matthew Ghermezi, Neil E Kay, J...> ;Experimental Hematology. 2022 Jul 1
• 42 citations
  Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma.
  Reona Sakemura, Mehrdad Hefazi, Elizabeth L Siegler, Michelle J Cox, Daniel P Larson, Michael J Hansen, Claudia Manriquez Roman, Kendall J Schick, Ismail Can, Erin E T...> ;Blood. 2022 Jun 30
• 7 citations
  GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity.
  Michelle J Cox, Claudia Manriquez Roman, Erin E Tapper, Elizabeth L Siegler, Dale Chappell, Cameron Durrant, Omar Ahmed, Sutapa Sinha, Raphael Mwangi, Nancy S Scott, M...> ;Leukemia. 2022 Jun 1
• 1 citations
  Associations of history of vaccination and hospitalization due to infection with risk of monoclonal B-cell lymphocytosis.
  Nicholas J Boddicker, Sara J Achenbach, Sameer A Parikh, Geffen Kleinstern, Esteban Braggio, Aaron D Norman, Kari G Rabe, Celine M Vachon, Connie E Lesnick, Timothy G ...> ;Leukemia. 2022 May 1
• 8 citations
  Chronic lymphocytic leukemia (CLL) with Reed-Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter?
  Rebecca L King, Alia Gupta, Paul J Kurtin, Wei Ding, Timothy G Call, Kari G Rabe, Saad S Kenderian, Jose F Leis, Yucai Wang, Susan M Schwager, Susan L Slager, Neil E K...> ;Blood Cancer Journal. 2022 Jan 28
• 2 citations
  Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia.
  Matthew Kaufman, Xiao-Jie Yan, Wentian Li, Emanuela M Ghia, Anton W Langerak, Laura Z Rassenti, Chrysoula Belessi, Neil E Kay, Frederic Davi, John C Byrd, Sarka Pospis...> ;Frontiers in Oncology. 2022 Jan 1
• 1 citations
  Differential transcriptomic profiling in ibrutinib-naïve versus ibrutinib-resistant Richter syndrome.
  Hanyin Wang, Shulan Tian, Qing Zhao, Wendy M. Blumenschein, Jennifer H. Yearley, Charla R. Secreto, Sutapa Sinha, Timothy G. Call, Yucai Wang, Sameer A. Parikh, Saad J...> ;Hematological Oncology. 2021 Nov 22
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Journal Articles

• GM-CSF Inhibition Reduces Cytokine Release Syndrome and Neuroinflammation but Enhances CAR-T Cell Function in Xenografts  
  Aaron J Johnson, Rosalie M Sterner, Neil E Kay, Blood
• Autoimmune Cytopenias in Patients with Chronic Lymphocytic Leukaemia Treated with Ibrutinib in Routine Clinical Practice at an Academic Medical Centre  
  Sameer A Parikh, Tait D Shanafelt, Paul J Hampel, Jose F Leis, Neil E Kay, Wei Ding, Timothy G Call, Deborah Bowen, Eli Muchtar, British Journal of Haematology
• Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity  
  Neil Kay, MD, Thrombosis and Haemostasis

Abstracts/Posters

• The Role of Imaging in Predicting Time to First Treatment and Overall Survival in Individuals with CLL-like High Count Monoclonal B-Cell Lymphocytosis
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• A Role for TNF-_ in Chronic Lymphocytic Leukemia Bone Marrow Hematopoietic Dysfunction
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• BTK and/or PLCG2 Mutations in Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Ibrutinib: Characteristics and Outcomes at the Time of Progression
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• _-Catenin and Axl Receptor Tyrosine Kinase Modulation in CLL B-Cells with Co-Culture on Marrow Stromal Cells: Implications for Drug Resistance
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Improved Anti-Tumor Response of Chimeric Antigen Receptor T Cell (CART) Therapy after GM-CSF Inhibition is Mechanistically Supported By a Novel Direct Interaction of G...
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Targeting of CD19 By Tafasitamab Does Not Impair CD19 Directed Chimeric Antigen Receptor T Cell Activity in Vitro
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Development of a Sensitive and Efficient Reporter Platform for the Detection of Chimeric Antigen Receptor T Cell Expansion, Trafficking, and Toxicity
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Circulating Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia (CLL)
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Tumor Mutational Load and Germline Polygenic Risk Score Predicts Time-to-First Treatment in Chronic Lymphocytic Leukemia (CLL) and High-Count Monoclonal B Cell Lymphoc...
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• A Randomized Phase 2 Study Comparing Acalabrutinib with or without Obinutuzumab in the Treatment of Early Stage High Risk Patients with Chronic Lymphocytic Leukemia (C...
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Developmental DNA Methylation Subtype Predicts Progression to Treatment and Survival in High-Count Monoclonal B Lymphocytosis
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Ibrutinib and Rituximab Provides Superior Clinical Outcome Compared to FCR in Younger Patients with Chronic Lymphocytic Leukemia (CLL): Extended Follow-up from the E19...
  Neil E. Kay, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

• Clinical Characteristics and Outcomes of Chronic Lymphocytic Leukemia Patients with Richter Transformation 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Size Matters: Identification of Larger Size CD19 Positive Extracellular Vesicles in Chronic Lymphocytic Leukemia That Inhibit Chimeric Antigen Receptor T Cell Functions 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Telomere Length Is Associated with Epigenetic Programming in CLL and Is a Superior Predictor of Clinical Outcome with the Ability to Bifurcate Patients with the Same C... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Clinical Characteristics and Outcomes of Chronic Lymphocytic Leukemia Patients with Richter Transformation 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Size Matters: Identification of Larger Size CD19 Positive Extracellular Vesicles in Chronic Lymphocytic Leukemia That Inhibit Chimeric Antigen Receptor T Cell Functions 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Ibrutinib-Based Therapy Improves Anti-Tumor T Cell Killing Function Allowing Effective Pairing with Anti-PD-L1 Immunotherapy Compared to Traditional FCR Chemoimmunothe... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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