PatrickAKupelianMDFASTRO

PubMed

• 7 citations
  RapidPlan hippocampal sparing whole brain model version 2-how far can we reduce the dose?
  Hefei Liu, Ryan Clark, Anthony Magliari, Robert Foster, Francisco Reynoso, Matthew Schmidt, Vinai Gondi, Christopher Abraham, Heather Curry, Patrick Kupelian, Deepak K...> ;Medical Dosimetry. 2022 May 3
• Radiation Therapy for Prostate Cancer Using HYpofractionation Directed by UltraSound (RAPHYDUS): A Brazilian Public Health Care System Study.
  Fabio de Lima Costa Faustino, Wanessa Fernanda Altei, Heloisa Pelisser Canton, Leonardo Morato, Livia Loami Ruys Jorge de Paula, Gabriela Bernal Salvador, Diego de Sou...> ;Practical Radiation Oncology. 2022 Apr 22
• 15 citations
  Interplay Between Duration of Androgen Deprivation Therapy and External Beam Radiotherapy With or Without a Brachytherapy Boost for Optimal Treatment of High-risk Pros...
  Amar U Kishan, Alison Steigler, James W Denham, Almudena Zapatero, Araceli Guerrero, David Joseph, Xavier Maldonado, Jessica K Wong, Bradley J Stish, Robert T Dess, Av...> ;JAMA Oncology. 2022 Mar 1
• 12 citations
  Performance of a Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography-Derived Risk-Stratification Tool for High-risk and Very High-risk ...
  Michael Xiang, Ting Martin Ma, Ricky Savjani, Erqi L Pollom, R Jeffrey Karnes, Tristan Grogan, Jessica K Wong, Giovanni Motterle, Jeffrey J Tosoian, Bruce J Trock, Eri...> ;JAMA Network Open. 2021 Dec 1
• 6 citations
  Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features.
  Amar U. Kishan, R. Jeffrey Karnes, Tahmineh Romero, J.K. Wong, Giovanni Motterle, Jeffrey J. Tosoian, Bruce J. Trock, Eric A. Klein, Bradley J. Stish, Robert T. Dess, ...> ;JAMA Network Open. 2021 Jul 1
• A novel external beam radiotherapy method for cervical cancer patients using virtual straight or bending boost areas; an in-silico feasibility study.
  L. Cozzi, Sushil Beriwal, Esa Kuusela, Supriya Chopra, Hester Burger, Nanette Joubert, Antonella Fogliata, Jai Prakash Agarwal, P.A. Kupelian> ;Radiation Oncology. 2021 Jun 14
• 12 citations
  Patterns of Clinical Progression in Radiorecurrent High-risk Prostate Cancer.
  R. Philipson, Tahmineh Romero, J.K. Wong, Bradley J. Stish, Robert T. Dess, Daniel E. Spratt, Avinash Pilar, Chandana A. Reddy, Trude B. Wedde, Wolfgang Lilleby, Ryan ...> ;European Urology. 2021 May 10
• 16 citations
  Identifying the Best Candidates for Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography as the Primary Staging Approach Among Men with ...
  Ting Martin Ma, Andrei Gafita, David Shabsovich, Jesus E. Juarez, Tristan Grogan, Pan Thin, Wesley R Armstrong, Ida Sonni, Kathleen Nguyen, Vincent Lok, Robert E. Reit...> ;European Urology Oncology. 2021 Feb 15
• 22 citations
  Stereotactic Body Radiotherapy for High-Risk Localized Carcinoma of the Prostate (SHARP) Consortium: Analysis of 344 Prospectively Treated Patients.
  Ritchell van Dams, Naomi Y. Jiang, Donald B. Fuller, Andrew Loblaw, Tommy Jiang, Alan J. Katz, Sean P. Collins, Nima Aghdam, Simeng Suy, Kevin L. Stephans, Ye Yuan, Ni...> ;International Journal of Radiation Oncology, Biology, Physics. 2021 Jan 23
• 19 citations
  Dose-response with stereotactic body radiotherapy for prostate cancer: A multi-institutional analysis of prostate-specific antigen kinetics and biochemical control.
  Rebecca Levin-Epstein, Naomi Y. Jiang, Xiaoyan Wang, Shrinivasa K. Upadhyaya, Sean P. Collins, Simeng Suy, Nima Aghdam, Constantine Mantz, Alan J. Katz, Leszek Miszczy...> ;Radiotherapy and Oncology. 2021 Jan 1
• 15 citations
  Prostate-specific antigen kinetics and biochemical control following stereotactic body radiation therapy, high dose rate brachytherapy, and low dose rate brachytherapy...
  Rebecca Levin-Epstein, Ryan Cook, J. Karen Wong, Richard G. Stock, D. Jeffrey Demanes, Sean P. Collins, Nima Aghdam, Simeng Suy, Constantine Mantz, Alan J. Katz, Nicho...> ;Radiotherapy and Oncology. 2020 Oct 1
• 11 citations
  The intraprostatic immune environment after stereotactic body radiotherapy is dominated by myeloid cells.
  Nicholas G. Nickols, Ekambaram Ganapathy, Christine Nguyen, Nathanael Kane, Lin Lin, Silvia Diaz-Perez, Ramin Nazarian, Colleen Mathis, Care Felix, Vince Basehart, Naz...> ;Prostate Cancer and Prostatic Diseases. 2021 Mar 1
• 8 citations
  Phase 1 Trial of Stereotactic Body Radiation Therapy Neoadjuvant to Radical Prostatectomy for Patients With High-Risk Prostate Cancer.
  Neil R. Parikh, Amar U. Kishan, Nathanael Kane, Silvia Diaz-Perez, Ekambaram Ganapathy, Ramin Nazarian, Carol Felix, Colleen Mathis, Margaret Bradley, Ankush Sachdeva,...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Jun 17
• 2 citations
  Development and Validation of a Comprehensive Multivariate Dosimetric Model for Predicting Late Genitourinary Toxicity Following Prostate Cancer Stereotactic Body Radi...
  Luca F. Valle, Dan Ruan, Audrey Dang, Rebecca Levin-Epstein, Ankur P. Patel, Joanne B. Weidhaas, Nicholas G. Nickols, Percy Lee, Daniel A. Low, S Qi, Christopher R. Ki...> ;Frontiers in Oncology. 2020 May 20
• 5 citations
  Gantry-Mounted Linear Accelerator-Based Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer.
  Audrey Dang, Rebecca Levin-Epstein, David Shabsovich, Minsong Cao, Christopher R. King, Fang-I Chu, Constantine Mantz, Kevin L. Stephans, Chandana A. Reddy, D. Andrew ...> ;Advances in Radiation Oncology. 2020 May 1
• 24 citations
  Clinical Assessment of Prostate Displacement and Planning Target Volume Margins for Stereotactic Body Radiotherapy of Prostate Cancer.
  Rebecca Levin-Epstein, George Qiao-Guan, Jesus E. Juarez, Zhouhuizi Shen, Michael L. Steinberg, Dan Ruan, Luca F. Valle, Nicholas G. Nickols, Patrick A. Kupelian, Chri...> ;Frontiers in Oncology. 2020 Apr 16
• A Prospective Multi-Institutional Phase I/II Trial of Step-Wise Dose-per-Fraction Escalation in Low and Intermediate Risk Prostate Cancer
  Mark A. Ritter, Patrick A. Kupelian, Daniel G. Petereit, Colleen A. Lawton, Nick Anger, Heather M. Geye, Rick Chappell, Jeffrey D. Forman> ;Practical Radiation Oncology. 2020 Mar 10
• 32 citations
  Local Failure and Survival After Definitive Radiotherapy for Aggressive Prostate Cancer: An Individual Patient-level Meta-analysis of Six Randomized Trials.
  Amar U. Kishan, Fang-I Chu, Christopher R. King, W. Seiferheld, Daniel E. Spratt, Phuoc T. Tran, Xiaoyan Wang, Stephanie E. Pugh, Kiri A. Sandler, Michel Bolla, Philip...> ;European Urology. 2020 Feb 1
• 10 citations
  Treatment planning comparison of volumetric modulated arc therapy employing a dual-layer stacked multi-leaf collimator and helical tomotherapy for cervix uteri
  S. Panda, Jamema Swamidas, Supriya Chopra, Akshay Mangaj, Antonella Fogliata, P.A. Kupelian, Jai Prakash Agarwal, Luca Cozzi> ;Radiation Oncology. 2020 Jan 30
• 16 citations
  Prostate-only Versus Whole-pelvis Radiation with or Without a Brachytherapy Boost for Gleason Grade Group 5 Prostate Cancer: A Retrospective Analysis
  Kiri A. Sandler, Ryan Cook, Jay P. Ciezki, Ashley E. Ross, Mark Pomerantz, Paul L. Nguyen, Talha Shaikh, Phuoc T. Tran, Richard G. Stock, Gregory S. Merrick, D.J. Dema...> ;European Urology. 2020 Jan 1
• 16 citations
  Enhancing Career Paths for Tomorrow's Radiation Oncologists.
  Neha Vapiwala, Charles R. Thomas, Surbhi Grover, Mei Ling Yap, Timur Mitin, Lawrence N. Shulman, Mary Gospodarowicz, J.M. Longo, Daniel G. Petereit, Ronald D. Ennis, J...> ;International Journal of Radiation Oncology, Biology, Physics. 2019 Sep 1
• 17 citations
  Ten-Year Outcomes of Moderately Hypofractionated (70 Gy in 28 fractions) Intensity Modulated Radiation Therapy for Localized Prostate Cancer.
  Ibrahim Abu-Gheida, Chandana A. Reddy, Rupesh Kotecha, Michael Weller, Chirag Shah, Patrick A. Kupelian, Omar Y. Mian, Jay P. Ciezki, Kevin L. Stephans, Rahul D. Tendu...> ;International Journal of Radiation Oncology, Biology, Physics. 2019 Jun 1
• 6 citations
  Association between Long-Term Second Malignancy Risk and Radiation: A Comprehensive Analysis of the Entire Surveillance, Epidemiology, and End Results Database (1973-2...
  Chenyang Wang, Amar U. Kishan, James B. Yu, Ann C. Raldow, Christopher R. King, Keisuke S. Iwamoto, Fang-I Chu, Michael L. Steinberg, Patrick A. Kupelian> ;Advances in Radiation Oncology. 2019 May 15
• 200 citations
  Long-term Outcomes of Stereotactic Body Radiotherapy for Low-Risk and Intermediate-Risk Prostate Cancer.
  Amar U. Kishan, Audrey Dang, Alan J. Katz, Constantine Mantz, Sean P. Collins, Nima Aghdam, Fang-I Chu, Irving D. Kaplan, Limor Appelbaum, Donald B. Fuller, Robert M. ...> ;JAMA Network Open. 2019 Feb 1
• 5 citations
  Underutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer.
  Chenyang Wang, Ann C. Raldow, Nicholas G. Nickols, Paul L. Nguyen, Daniel E. Spratt, Robert T. Dess, James B. Yu, Christopher R. King, Fang-I Chu, Karim Chamie, Mark S...> ;European Urology Oncology. 2021 Apr 1
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Journal Articles

• Prediction of Intrafraction Prostate Motion: Accuracy of Pre- and Post-Treatment Imaging and Intermittent Imaging.  
  Noel C, Parikh P, Roy M, Kupelian PA, Mahadevan A, Weinstein G, Enke C, Flores N, Beyer D, Levine L, Int J Radiat Oncol Biol Phys
• Evaluation of geometric changes of parotid glands during head and neck cancer radiotherapy using daily MVCT and automatic deformable registration.  
  Lee C, Langen KM, Lu W, Haimerl J, Schnarr E, Ruchala KJ, Olivera GH, Meeks SL, Kupelian PA, Shellenberger TD, Mañon RR, Radiother Oncol
• Performance evaluation of an improved optical computed tomography polymer gel dosimeter system for 3D dose verification of static and dynamic phantom deliveries.  
  Lopatiuk-Tirpak O, Langen K, Meeks S, Kupelian PA, Zeidan O, Maryanski M, Med Phys
• Real-time simulation of 4D lung tumor radiotherapy using a breathing model.  
  Santhanam A, Willoughby T, Shah A, Meeks S, Rolland J, Kupelian PA, Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv
• Correlation between dosimetric effect and intrafraction motion during prostate treatments delivered with helical tomotherapy.  
  Langen K, Lu W, Ngwa W, Willoughby T, Chauhan B, Meeks S, Kupelian PA, Olivera G, Phys Med Biol
• Hypofractionation for Prostate Cancer.  
  Ritter M, Forman J, Kupelian PA, Lawton C, Petereit D, Cancer J
• Selective Radioprotection of Normal Tissues with Cerium Oxide Nanoparticles.  
  Colon J, Herrera L, Smith J, Patil S, Komanski C, Kupelian PA, Seal S, Jenkins W, Baker C, Nanomedicine
• Real-time motion-adaptive-optimization (MAO) in TomoTherapy.  
  Lu W, Chen M, Ruchala K, Chen Q, Langen K, Kupelian PA, Olivera G, Phys Med Biol
• Modeling simulation and visualization of conformal 3D lung tumor dosimetry.  
  Santhanam A, Willoughby T, Meeks S, Rolland J, Kupelian PA, Phys Med Biol
• Validation of a computational method for assessing the impact of intra-fraction motion on helical tomotherapy plans.  
  Ngwa W, Meeks S, Kupelian PA, Schnarr E, Langen K, Phys Med Biol
• American Society for Therapeutic Radiology and Oncology (ASTRO) and American College of Radiology (ACR) practice guidelines for image-guided radiation therapy (IGRT).  
  Potters L, Gaspar L, Kavanagh B, Galvin J, Hartford A, Hevezi J, Kupelian PA, Mohiden N, Samuels M, Timmerman R, Tripuraneni P, Vlachaki M, Xing L, Rosenthal S, Int J Radiat Oncol Biol Phys
• Cerium Oxide Nanoparticles Protect GastroIntestinal Epithelium from Radiation-Induced Damage by Reduction of ROS and Upregulation of Super Oxide Dismutase-2.  
  Colon J, Hsieh N, Ferguson A, Kupelian PA, Seal S, Jenkins D, Baker C, Nanomedicine
• The role of overall treatment time in the outcome of radiotherapy of prostate cancer: An analysis of biochemical failure in 4839 men treated between 1987 and 1995.  
  Thames H, Kuban D, Levy L, Horwitz E, Kupelian PA, Martinez A, Michalski J, Pisansky T, Sandler H, Shipley W, Zelefsky M, Zietman A, Radiother Oncol
• Dosimetric evaluation of a novel polymer gel dosimeter for proton therapy.  
  Zeidan O, Sriprisan S, Lopatiuk-Tirpak O, Kupelian PA, Meeks S, Hsi W, Li Z, Palta J, Maryanski M, Med Phys
• A GPU-based framework for modeling real-time 3D lung tumor conformal dosimetry with subject-specific lung tumor motion.  
  Min Y, Santhanam A, Neelakkantan H, Ruddy B, Meeks S, Kupelian PA, Phys Med Biol
• Visualization of 3D Volumetric Lung Dynamics for Real-Time External Beam Lung Radiotherapy.  
  Santhanam AP, Neelakkantan H, Min Y, Papp N, Bhargava A, …, Ilegbusi O, Ruddy H, Rolland P, Meeks L, Kupelian PA, Visualization of 3D Volumetric Lung Dynamics for Real-Time External Beam Lung Radiotherapy.
• An evaluation of intrafraction motion of the prostate in the prone and supine positions using electromagnetic tracking.  
  Shah A, Kupelian PA, Willoughby T, Langen K, Meeks S, Radiother Oncol
• Image Guidance During Head-and-Neck Cancer Radiation Therapy: Analysis of Alignment Trends with In-Room Cone-Beam Computed Tomography Scans.  
  Zumsteg Z, Demarco J, Lee S, Steinberg M, Lin C, McBride W, Lin K, Wang P, Kupelian PA, Lee P, Int J Radiat Oncol Biol Phys
• Prostate Intrafraction Translation Margins for Real-Time Monitoring and Correction Strategies.  
  Litzenberg D, Balter J, Hadley S, Hamstra D, Willoughby T, Kupelian PA, Djemil T, Mahadevan A, Jani S, Weinstein G, Solberg T, Enke C, Levine L, Sandler H, Prostate Cancer
• Initial dissection of the lateral fascia reduces the positive margin rate in radical prostatectomy.  
  Klein E, Kupelian PA, Tuason L, Levin H, Urology
• Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy.  
  Grimm P, Billiet I, Bostwick D, Dicker A, Frank S, Immerzeel J, Keyes M, Kupelian PA, Lee W, Machtens S, Mayadev J, Moran B, Merrick G, Millar J, Roach M, Stock R, Shi..., BJU Int
• Evolving treatment plan quality criteria from institution-specific experience.  
  Ruan D, Shao W, Demarco J, Tenn S, King C, Low D, Kupelian PA, Steinberg M, Med Phys
• Computational fluid dynamics modeling of airflow inside lungs using heterogenous anisotropic lung tissue elastic properties.  
  Ilegbusi O, Li Z, Min Y, Meeks S, Kupelian PA, Santhanam A, Stud Health Technol Inform
• Resectable esophageal carcinoma: Local control with neoadjuvant chemotherapy and radiation therapy.  
  Chidel M, Rice T, Adelstein D, Kupelian PA, Suh J, Becker M, Radiology
• Treatment of endometrial carcinoma with radiotherapy alone.  
  Kupelian PA, Eifel P, Tornos C, Burke T, Delclos L, Oswald M, Int J Radiat Oncol Biol Phys
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Books/Book Chapters

• Management of Prostate Cancer. 
  Chapter: Management of Prostate Cancer. 
  Kupelian PAEditors: Klein EA.Humana Press
• Management of Prostate Cancer. 
  Chapter: Androgen Deprivation and Radiation Therapy for Localized Prostate Cancer. 
  Kupelian PA,Carlson TEditors: Klein EA.Humana Press
• Management of Prostate Cancer. 
  Chapter: Conformal External Beam Radiotherapy. 
  Mahadevan A, Kupelian PAEditors: Klein EA.Humana Press
• Management of Prostate Cancer. 
  Chapter: Counseling Patients with Localized Prostate Cancer: Radiation or Surgery? 
  Klein E and Kupelian PAEditors: Klein EA.Humana Press
• Integrating New Technologies into the Clinic: Monte Carlo and Image-Guided Radiation Therapy. 
  Chapter: Tomotherapy’s implementation of image-guided and dose-guided adaptive radiation therapy. 
  Langen K, Meeks S, Kupelian PA, Ruchala K, Lu W, Haimerl J, Chen Q, Schnarr E, Olivera GEditors: Curran B, Balter J, Chetty I.
• Cancer Imaging. 
  Chapter: Megavolage Computed Tomography Imaging. 
  Zeidan O, Meeks S, Langen K, Wagner T, Kupelian PAEditors: Hayat MA.Academic Press
• Scientific Concepts and Clinical Experiences. 
  Chapter: Hypofractionation for localized prostate cancer. 
  Kupelian PAEditors: A Pollack, M Ahmed.LumiText Publishing
• Lung Imaging and Computer Aided Diagnosis. 
  Chapter: Four-Dimensional Computed Tomography Lung Registration Methods. 
  Page 85 - 108Santhanam A, Min Y, Rolland J, Imielinska C, Kupelian PAEditors: Jasjit S. Suri.CRC Press
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Lectures

• Cancer Imaging and Radiation Therapy Symposium 
  American Society for Radiation Oncology, Lake Buena Vista, Florida - 2/8/2013
• Lectures on cell survival curves and time-dose fractionation in radiotherapy. 
  Cleveland Clinic Foundation Radiobiology
• Prostate cancer: Management issues. 
  Cleveland Clinic Foundation
• Prostate cancer: Introduction to natural history and pathophysiology. 
  Cleveland Clinic Foundation
• Introduction to Radiosurgery. 
  Jornada Rede D’Or, Rio de Janeiro, Brazil
• Prostate cancer: External beam radiotherapy techniques. 
  Cleveland Clinic Foundation
• Approach to Modern Radiotherapy. 
  Jornada Rede D’Or 2009, Rio de Janeiro, Brazil
• Prostate cancer: Radiotherapeutic options. 
  Cleveland Clinic Foundation
• Prostate cancer: The CCF experience. 
  Cleveland Clinic Foundation.
• Prostate Radiosurgery. 
  Jornada Rede D’Or 2009, Rio de Janeiro, Brazil
• Prostate cancer: Current management. 
  Cleveland Clinic Foundation
• Genitourinary cancers: Management. 
  Cleveland Clinic Foundation
• Presenter, Users’ meeting. 
  Computerized Medical Systems, St Louis
• International Conference on the Clinical Use of TomoTherapy. 
  Technical University Munich, Munich, Germany
• Prostate cancer: Current management. 
  Cleveland Clinic Foundation
• Helical Tomotherapy: Prostate Cancer. 
  Technical University Munich, Munich, Germany
• Presenter, Users’ meeting. 
  Computerized Medical Systems, Boca Raton
• Genitourinary cancers: Management. 
  Cleveland Clinic Foundation
• Report on Helical Tomotherapy in North America. 
  Technical University Munich, Munich, Germany
• Current treatment techniques for localized prostate cancer. 
  Cleveland Clinic Foundation
• Current treatment techniques for localized prostate cancer. 
  Cleveland Clinic Foundation
• Current treatment techniques for localized prostate cancer. 
  Cleveland Clinic Foundation
• Radiotherapy For Localized Advanced Prostate Cancer. 
  EMUC (European Multidisciplinary Meeting on Urological Cancers), Barcelona, Spain
• Presenter, Users’ meeting. 
  Computerized Medical Systems, Philadelphia
• Localized prostate cancer in the PSA era; the CCF experience. 
  Cleveland Clinic Foundation Cancer Center
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