PhilanaLingLinMD

PubMed

• Antibiotic treatment modestly reduces protection againstreinfection in macaques.
  Sharie Keanne Ganchua, Pauline Maiello, Michael Chao, Forrest Hopkins, Douaa Mugahid, JoAnne L Flynn, Philana Ling Lin, Sarah M Fortune> ;Infection and Immunity. 2024 Apr 9
• Nontuberculous Mycobacterial Infections in Pediatric Solid Organ Transplant and Hematopoietic Cell Transplant Recipients.
  Jonathan Albert, Charles L Daley, Philana Ling Lin> ;Journal of the Pediatric Infectious Diseases Society. 2024 Feb 28
• Author Correction: Intravenous Bacille Calmette-Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis.
  Larson, E., Ellis-Connell, A., Rodgers, M., Gubernat, A., Gleim, J., Moriarty, R., Balgeman, A., Ameel, C., Jauro, S., Tomko, J., Kracinovsky, K., Maiello, P., Borish,...> ;Nature Microbiology. 2024 Feb 14
• CD4T cells are homeostatic regulators duringreinfection.
  Bromley, J., Ganchua, S., Nyquist, S., Maiello, P., Chao, M., Borish, H., Rodgers, M., Tomko, J., Kracinovsky, K., Mugahid, D., Nguyen, S., Wang, D., Rosenberg, J., Kl...> ;Biorxiv. 2023 Dec 21
• Antibiotic treatment modestly reduces protection against Mycobacterium tuberculosis reinfection in macaques.
  Sharie Keanne Ganchua, Pauline Maiello, Michael Chao, Forrest Hopkins, Douaa Mugahid, Philana Ling Lin, Sarah M Fortune, JoAnne L Flynn> ;Biorxiv. 2024 Feb 24
• 1 citations
  Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates.
  Ishida, E., Corrigan, D., Chen, T., Liu, Y., Kim, R., Song, L., Rutledge, T., Magee, D., Lowary, T., Achkar, J., LaBaer, J., Lin, P.> ;Ebiomedicine. 2024 Jan 1
• 7 citations
  CD8+ lymphocytes are critical for early control of tuberculosis in macaques.
  Caylin G Winchell, Sarah K Nyquist, Michael C Chao, Pauline Maiello, Amy J Myers, Forrest Hopkins, Michael Chase, Hannah P Gideon, Kush V Patel, Joshua D Bromley, Andr...> ;The Journal of Experimental Medicine. 2023 Dec 4
• A "suicide" BCG strain provides enhanced immunogenicity and robust protection againstin macaques.
  Smith, A., Su, H., Wallach, J., Liu, Y., Maiello, P., Borish, H., Winchell, C., Simonson, A., Rodgers, M., Fillmore, D., Sakal, J., Lin, K., Schnappinger, D., Ehrt, S....> ;Biorxiv. 2023 Nov 22
• 3 citations
  Intravenous Bacille Calmette-Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis.
  Erica C Larson, Amy L Ellis-Connell, Mark A Rodgers, Abigail K Gubernat, Janelle L Gleim, Ryan V Moriarty, Alexis J Balgeman, Cassaundra L Ameel, Solomon Jauro, Jaime ...> ;Nature Microbiology. 2023 Nov 1
• 4 citations
  Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.
  Maral Budak, Joseph M Cicchese, Pauline Maiello, H Jacob Borish, Alexander G White, Harris B Chishti, Jaime Tomko, L James Frye, Daniel Fillmore, Kara Kracinovsky, Jen...> ;Plos Computational Biology. 2023 Jun 1
• 17 citations
  Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques.
  Patricia A Darrah, Joseph J Zeppa, Chuangqi Wang, Edward B Irvine, Allison N Bucsan, Mark A Rodgers, Supriya Pokkali, Joshua A Hackney, Megha Kamath, Alexander G White...> ;Cell Host & Microbe. 2023 Jun 14
• 2 citations
  Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis.
  Erica C Larson, Amy L Ellis-Connell, Mark A Rodgers, Abigail K Gubernat, Janelle L Gleim, Ryan V Moriarty, Alexis J Balgeman, Cassaundra L Ameel, Solomon Jauro, Jaime ...> ;Research Square. 2023 Apr 17
• 1 citations
  Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas.
  Nicole L Grant, Kristen Kelly, Pauline Maiello, Helena Abbott, Shelby O'Connor, Philana Ling Lin, Charles A Scanga, JoAnne L Flynn> ;Mbio. 2023 Jun 27
• 2 citations
  Characterizing the Spectrum of Latent Mycobacterium tuberculosis in the Cynomolgus Macaque Model: Clinical, Immunologic, and Imaging Features of Evolution.
  Jessica Marie Medrano, Pauline Maiello, Tara Rutledge, Jaime Tomko, Mark A Rodgers, Daniel Fillmore, L James Frye, Christopher Janssen, Edwin Klein, JoAnne L Flynn, Ph...> ;The Journal of Infectious Diseases. 2023 Feb 14
• "Hot Tub Lung" With M. avium complex in an Immunocompetent Adolescent.
  Benjamin Waletzko, Philana Ling Lin, Santiago M C Lopez> ;The Pediatric Infectious Disease Journal. 2023 Mar 1
• Characterization of natural killer cells in the blood and airways of cynomolgus macaques during Mycobacterium tuberculosis infection.
  Collin R Diedrich, Tara Rutledge, Tonilynn M Baranowski, Pauline Maiello, Philana Ling Lin> ;Journal of Medical Primatology. 2023 Feb 1
• 5 citations
  Decrease in Pediatric Invasive Pneumococcal Disease During the COVID-19 Pandemic.
  Adriana Sarmiento Clemente, Sheldon L Kaplan, William J Barson, Philana Ling Lin, José R Romero, John S Bradley, Tina Q Tan, Pia S Pannaraj, Laurence B Givner, Kristin...> ;Journal of the Pediatric Infectious Diseases Society. 2022 Sep 29
• 7 citations
  T cell transcription factor expression evolves over time in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques.
  Nicole L Grant, Pauline Maiello, Edwin Klein, Philana Ling Lin, H Jacob Borish, Jaime Tomko, L James Frye, Alexander G White, Denise E Kirschner, Joshua T Mattila, JoA...> ;Cell Reports. 2022 May 17
• 68 citations
  Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.
  Hannah P Gideon, Travis K Hughes, Constantine N Tzouanas, Marc H Wadsworth 2nd, Ang Andy Tu, Todd M Gierahn, Joshua M Peters, Forrest F Hopkins, Jun-Rong Wei, Conner K...> ;Immunity. 2022 May 10
• 2 citations
  SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Co-Infection.
  Kaho H Tisthammer, Christopher Kline, Tara Rutledge, Collin R Diedrich, Sergio Ita, Philana Ling Lin, Zandrea Ambrose, Pleuni S Pennings> ;Viruses. 2021 Dec 29
• 6 citations
  Retention of 64 Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques.
  Joshua T. Mattila, Wissam Beaino, Alexander G. White, Lea Nyiranshuti, Pauline Maiello, Jaime Tomko, L. James Frye, Daniel Fillmore, Charles A. Scanga, Philana Ling Li...> ;ACS Infectious Diseases. 2021 Jul 13
• 13 citations
  Visualizing the dynamics of tuberculosis pathology using molecular imaging.
  Alvaro A. Ordonez, Elizabeth W. Tucker, Carolyn J. Anderson, Claire L. Carter, Shashank Ganatra, Deepak Kaushal, Igor Kramnik, Philana Ling Lin, Cressida A. Madigan, S...> ;The Journal of Clinical Investigation. 2021 Mar 1
• 14 citations
  Measurement of leukocyte trafficking kinetics in macaques by serial intravascular staining.
  E. Lake Potter, Hannah P. Gideon, Victor Tkachev, Giulia Fabozzi, Alexander Chassiakos, Constantinos Petrovas, Patricia A. Darrah, Philana Ling Lin, Kathryn E. Foulds,...> ;Science Translational Medicine. 2021 Jan 13
• 2 citations
  Treatment of latent M. tuberculosis infection and use of antiretroviral therapy to prevent tuberculosis.
  Timothy R. Sterling, Philana Ling Lin> ;The Journal of Clinical Investigation. 2020 Oct 1
• 20 citations
  SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis.
  Collin R. Diedrich, Tara Rutledge, Pauline Maiello, Tonilynn M Baranowski, Alexander G. White, H. Jacob Borish, Paul Karell, Forrest F. Hopkins, Jessica Brown, Sarah M...> ;Plos Pathogens. 2020 Jul 30
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Journal Articles

• SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis  
  Diedrich, plos pathogen
• Lymph Nodes Are Sites of Prolonged Bacterial Persistence During Mycobacterium Tuberculosis Infection in Macaques  
  Philana Lin, MD, PLoS One
• Concurrent Infection with Mycobacterium Tuberculosis Confers Robust Protection Against Secondary Infection in Macaques  
  Sarah M Fortune, Philana Ling Lin, PLoS One
• The End of the Binary Era: Revisiting the Spectrum of Tuberculosis  
  Philana Lin, MD, The Journal of Immunology
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