Quynh-ThuXuanLeMDFASTRO

Radiation Oncology • Stanford, CA

Head & Neck

Professor, Radiation Oncology, Stanford University Medical Center

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Office
875 Blake Wilbur drive
Stanford, CA 94305
Phone+1 650-498-5032

Fax+1 650-725-8231
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Summary

Dr. Quynh-Thu Le is a radiation oncologist in Stanford, CA and is affiliated with multiple hospitals in the area, including Lucile Packard Children's Hospital Stanford, Stanford Health Care, and VA Palo Alto Health Care System. She received her medical degree from University of California San Francisco School of Medicine and has been in practice 24 years. She specializes in head & neck.

Education & Training

University of California (San Francisco)Residency, Radiation Oncology, 1994 - 1997
Alameda Health System-Highland HospitalInternship, Transitional Year, 1993 - 1994
University of California San Francisco School of MedicineClass of 1993

Certifications & Licensure

CA State Medical License 1994 - 2024
American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2008-2014
America's Top Doctors for Cancer Castle Connolly, 2007-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

S0004: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-stage Small Cell Lung Cancer Start of enrollment: 2000 Oct 01
Completed
Phase 1
Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer Start of enrollment: 2003 Sep 01
Completed
Phase 2
Cisplatin and ZD1839 + Re-Irradiation in Recurrent Squamous Cell Cancer of the Head and Neck Start of enrollment: 2002 Jun 01
Completed
Phase 1
Identification of Serum Markers For Tumor Hypoxia in Non-Small Cell Lung Cancers Start of enrollment: 2000 Sep 01
Completed
A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations Start of enrollment: 2001 Nov 01
Completed
Treatment Outcomes and Quality of Life After IMRT Treatments of Head and Neck Cancers Start of enrollment: 2003 Apr 01
Completed
The Role of FDG PET in Radiation Treatment Planning for Head and Neck Cancers Start of enrollment: 2003 May 01
Completed
Indirect Magnetic Resonance Lymphangiography of the Head and Neck Region Using Conventional Gadolinium-based Contrast Start of enrollment: 2003 Feb 01
Completed
Not Applicable
Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer Start of enrollment: 2002 Apr 02
Recruiting
Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy Start of enrollment: 2002 Jan 01
Recruiting
Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy Start of enrollment: 2007 Jul 01
Terminated
Phase 2
Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers Start of enrollment: 1998 Sep 01
Recruiting
Real-Time kV Imaging vs. Real-Time 3D Patient Surface Tracking for Head & Neck Cancer Start of enrollment: 2009 Oct 01
Terminated
Not Applicable
Imaging and Biomarkers of Hypoxia in Solid Tumors Start of enrollment: 2010 Dec 01
Terminated
Phase 1
Metabolic Reprogramming Therapy for Treatment of Recurrent Head and Neck Cancers Start of enrollment: 2010 Aug 01
Completed
Phase 1
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer Start of enrollment: 2013 Mar 22
Recruiting
Phase 2, Phase 3
Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery Start of enrollment: 2016 Feb 01
Completed
Early Phase 1
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Publications & Presentations

PubMed

1 citations
Surrogate endpoints in clinical trials of p16-positive squamous cell carcinoma of the oropharynx: an individual patient data meta-analysis.
Laila A Gharzai, Emily Morris, Krithika Suresh, Phuc Felix Nguyen-Tân, David I Rosenthal, Maura L Gillison, Paul M Harari, Adam S Garden, Shlomo Koyfman, Jimmy J Caude...> ;The Lancet. Oncology. 2024 Mar 1
The lipid-binding D4 domain of perfringolysin O facilitates the active loading of exogenous cargo into extracellular vesicles.
Opadele, A., Nishioka, S., Wu, P., Shirato, H., Nam, J., Onodera, Y., Le, Q.> ;FEBS Letters. 2024 Feb 1
First-Year Experience of Stereotactic Body Radiation Therapy/Intensity Modulated Radiation Therapy Treatment Using a Novel Biology-Guided Radiation Therapy Machine.
Shi, M., Simiele, E., Han, B., Pham, D., Palomares, P., Aguirre, M., Surucu, M., Kovalchuk, N., Gensheimer, M., Vitzthum, L., Le, Q.> ;Advances in Radiation Oncology. 2024 Jan 1
Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer.
Ko, R., Schüler, E., Kielar, K., Maxim, P., Hara, W., Abelson, J., Fleischmann, D., Louie, J., Hwang, G., Sze, D., Le, Q., Diehn, M., Kothary, N., Loo, B.> ;Radiotherapy and Oncology. 2024 Feb 1
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Callum Beach, David MacLean, Dominika Majorova, Stavros Melemenidis, Dhanya K Nambiar, Ryan K Kim, Gabriel N Valbuena, Silvia Guglietta, Carsten Krieg, Mahnaz Darvish-...> ;The Journal of Clinical Investigation. 2023 Dec 1
Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses.
Elaine Limkin, Pierre Blanchard, Benjamin Lacas, Jean Bourhis, Mahesh Parmar, Lisa Licitra, Quynh-Thu Le, Sue S Yom, Catherine Fortpied, Johannes Langendijk, Jan B Ver...> ;Radiotherapy and Oncology. 2024 Jan 1
3 citations
Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC.
Nathan T Wamsley, Emily M Wilkerson, Li Guan, Kyle M LaPak, Travis P Schrank, Brittany J Holmes, Robert W Sprung, Petra Erdmann Gilmore, Sophie P Gerndt, Ryan S Jackso...> ;Molecular & Cellular Proteomics. 2023 Nov 1
Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial.
Stuart J Wong, Pedro A Torres-Saavedra, Nabil F Saba, George Shenouda, Jeffrey M Bumpous, Robert E Wallace, Christine H Chung, Adel K El-Naggar, Clement K Gwede, Barba...> ;JAMA Oncology. 2023 Nov 1
Cancer Informatics for Cancer Centers: Sharing Ideas on How to Build an Artificial Intelligence-Ready Informatics Ecosystem for Radiation Oncology.
Bitterman, D., Gensheimer, M., Jaffray, D., Pryma, D., Jiang, S., Morin, O., Ginart, J., Upadhaya, T., Vallis, K., Buatti, J., Deasy, J., Hsiao, H., Chung, C., Fuller,...> ;JCO Clinical Cancer Informatics. 2023 Sep 1
9 citations
International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential ...
Matt Lechner, Yoko Takahashi, Mario Turri-Zanoni, Marco Ferrari, Jacklyn Liu, Nicholas Counsell, Davide Mattavelli, Vittorio Rampinelli, William Vermi, Davide Lombardi...> ;Journal of Neurological Surgery. Part B, Skull Base. 2023 Aug 1
4 citations
Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment.
Dhanya K Nambiar, Vignesh Viswanathan, Hongbin Cao, Weiruo Zhang, Li Guan, Manish Chamoli, Brittany Holmes, Christina Kong, Rachel Hildebrand, Amanda Jeanette Koong, R...> ;Cancer Research. 2023 Oct 2
1 citations
Lessons and Opportunities for Biomarker-Driven Radiation Personalization in Head and Neck Cancer.
Elham Rahimy, Michael F Gensheimer, Beth Beadle, Quynh-Thu Le> ;Seminars in Radiation Oncology. 2023 Jul 1
1 citations
Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial.
Nancy Y Lee, Jonathan Harris, John Kim, Adam Garden, James Mechalakos, David G Pfister, Anthony T C Chan, Kenneth Hu, A Dimitrios Colevas, Steven Frank, George Shenoud...> ;JAMA Network Open. 2023 Jun 1
Comparison of Real-Time PCR and Digital PCR for Detection of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma.
Jacob A Miller, ChunHong Huang, Fumiko Yamamoto, Malaya K Sahoo, Quynh-Thu Le, Benjamin A Pinsky> ;The Journal of Molecular Diagnostics. 2023 Jul 1
1 citations
F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results...
Rathan M Subramaniam, Lyudmila DeMora, Min Yao, Sue S Yom, Maura Gillison, Jimmy J Caudell, John Waldron, Ping Xia, Christine H Chung, Minh Tam Truong, Michelle Echeva...> ;Journal of Nuclear Medicine. 2023 Mar 1
Using a Culture Committee to Improve and Maintain a Positive Workplace Environment During a Pandemic.
Brianna Lau, Felicia Guo, John Valenton, Daniel Chang, Quynh-Thu Le, Kathleen Horst> ;Practical Radiation Oncology. 2023 Mar 1
8 citations
Radiotherapy and paclitaxel plus pazopanib or placebo in anaplastic thyroid cancer (NRG/RTOG 0912): a randomised, double-blind, placebo-controlled, multicentre, phase ...
Eric J Sherman, Jonathan Harris, Keith C Bible, Ping Xia, Ronald A Ghossein, Christine H Chung, Nadeem Riaz, G Brandon Gunn, Robert L Foote, Sue S Yom, Stuart J Wong, ...> ;The Lancet. Oncology. 2023 Feb 1
10 citations
Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions.
W K Jacky Lam, Ann D King, Jacob A Miller, Zhiwei Liu, Kelly J Yu, Melvin L K Chua, Brigette B Y Ma, Ming Yuan Chen, Benjamin A Pinsky, Pei-Jen Lou, John K S Woo, Wan-...> ;Journal of the National Cancer Institute. 2023 Apr 11
10 citations
NFE2L2 Mutations Enhance Radioresistance in Head and Neck Cancer by Modulating Intratumoral Myeloid Cells.
Li Guan, Dhanya K Nambiar, Hongbin Cao, Vignesh Viswanathan, Shirley Kwok, Angela B Hui, Yuan Hou, Rachel Hildebrand, Rie von Eyben, Brittany J Holmes, Junfei Zhao, Ch...> ;Cancer Research. 2023 Mar 15
1 citations
In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradi...
Michelle Jun, Harlan Pinto, Quynh-Thu Le, Andrew Quon, Wendy Hara, Jessie Coty, Alex McMillan, Rong Lu, Elzbieta Winters, Ruth Lira, A Dimitrios Colevas> ;Plos One. 2023 Jan 1
Reflections on the 2021 Accreditation Council for Graduate Medical Education and American Board of Radiology Family and Medical Leave of Absence Policies: An Opportuni...
Claire C Baniel, Daniella Klebaner, Beth M Beadle, Sara E Beltrán Ponce, Vinita Takiar, Iris C Gibbs, Scott G Soltys, Hilary P Bagshaw, Daniel T Chang, Quynh-Thu Le, E...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jan 1
4 citations
Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck ...
Jimmy J Caudell, Pedro A Torres-Saavedra, David I Rosenthal, Rita S Axelrod, Phuc Felix Nguyen-Tan, Eric J Sherman, Randal S Weber, James M Galvin, Adel K El-Naggar, A...> ;International Journal of Radiation Oncology, Biology, Physics. 2023 Jul 1
8 citations
International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pan...
Victor Ho-Fun Lee, Marlinda Adham, Wala Ben Kridis, Paolo Bossi, Ming-Yuan Chen, Imjai Chitapanarux, Vincent Gregoire, Sheng Po Hao, Cheryl Ho, Gwo Fuang Ho, Danita Ka...> ;The Lancet. Oncology. 2022 Dec 1
2 citations
Improving lung cancer screening rates among patients with head and neck cancer in a radiation oncology clinic.
Lina Soto, Shannon Nesbit, Meghan Ramsey, Michael F Gensheimer, Quynh Thu Le, Beth M Beadle, Natalie S Lui> ;Journal of Thoracic Disease. 2022 Dec 1
5 citations
Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma.
Jacob A Miller, Farshad Moradi, Vandana Sundaram, Rachel Liang, Carrie Zhang, Ngan Kim Nguyen, Faisal Akhtar, Yuhan Liu, Yulan Ren, Nima Harandi, Yingjie Weng, Erqi L ...> ;Head & Neck. 2022 Nov 1
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Journal Articles

International Guideline for the Delineation of the Clinical Target Volumes (CTV) for Nasopharyngeal Carcinoma
William M. Mendenhall, Qunyh-Thu Le, Nancy Y. Lee, Radiotherapy & Oncology

Press Mentions

RSNA 2022 Plenaries Highlight Radiology’s Value, Responsibility to PatientsJuly 19th, 2022
Traditional Chemotherapy Superior to New Alternative for Oropharyngeal CancersNovember 15th, 2018
NRG Oncology Selects Health Equity Fellows for 2024February 22nd, 2024

Grant Support

Targeting Galectin-1 With Radiation In Lung CancerNational Cancer Institute2012
A Novel Therapy For Radiation-Induced Xerostomia Using Human Salivary Stem CellsNational Institute Of Dental &Craniofacial Research2011
Osteopontin &Tumor Progression In Head And Neck CancersNational Cancer Institute2007–2011
Defining Molecular Markers For Tumor HypoxiaNational Cancer Institute2006–2010
Markers For Tumor Hypoxia In Head And Neck CancerNational Cancer Institute2001–2002