RajanSahMD

PubMed

• Mechanosensing in Metabolism.
  Tranter, J., Kumar, A., Nair, V., Sah, R.> ;Comprehensive Physiology. 2023 Dec 29
• Regulation of the Volume-Regulated Anion Channel Pore-Forming Subunit LRRC8A in the Intrahippocampal Kainic Acid Model of Mesial Temporal Lobe Epilepsy.
  Manolia R Ghouli, Carrie R Jonak, Rajan Sah, Todd A Fiacco, Devin K Binder> ;ASN Neuro. 2023 Jul 6
• 1 citations
  LRRC8A anion channels modulate vascular reactivity via association with myosin phosphatase rho interacting protein.
  Hyehun Choi, Michael R Miller, Hong-Ngan Nguyen, Jeffrey C Rohrbough, Stephen R Koch, Naoko Boatwright, Michael T Yarboro, Rajan Sah, W Hayes McDonald, Ryan J Stark, F...> ;FASEB Journal. 2023 Jul 1
• 1 citations
  Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release.
  Mustafa Balkaya, Preeti Dohare, Sophie Chen, Alexandra L Schober, Antonio M Fidaleo, Julia W Nalwalk, Rajan Sah, Alexander A Mongin> ;Iscience. 2023 May 19
• 2 citations
  A Critical Role for ERO1α in Arterial Thrombosis and Ischemic Stroke.
  Vishwanath Jha, Bei Xiong, Tripti Kumari, Gavriel Brown, Jinzhi Wang, Kyungho Kim, Jingu Lee, Nathan Asquith, John Gallagher, Lillian Asherman, Taylor Lambert, Yanyan ...> ;Circulation Research. 2023 May 26
• 7 citations
  Structural and functional analysis of human pannexin 2 channel.
  Zhihui He, Yonghui Zhao, Michael J Rau, James A J Fitzpatrick, Rajan Sah, Hongzhen Hu, Peng Yuan> ;Nature Communications. 2023 Mar 27
• Adipose-targeted SWELL1 deletion exacerbates obesity- and age-related nonalcoholic fatty liver disease.
  Susheel K Gunasekar, John Heebink, Danielle H Carpenter, Ashutosh Kumar, Litao Xie, Haixia Zhang, Joel D Schilling, Rajan Sah> ;JCI Insight. 2023 Mar 8
• Corrigendum to "LRRC8A-dependent volume-regulated anion channels contribute to ischemia-induced brain injury and glutamatergic input to hippocampal neurons" [Experimen...
  Jing-Jing Zhou, Yi Luo, Shao-Rui Chen, Jian-Ying Shao, Rajan Sah, Hui-Lin Pan> ;Experimental Neurology. 2022 Mar 1
• 11 citations
  Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
  Susheel K Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Pratik R Chheda, Chen Kang, David M Kern, Chau My-Ta, Joshua Maurer, John Heebink, Eva E Gerber, Wojciech J ...> ;Nature Communications. 2022 Feb 10
• 27 citations
  Mechanosensitive TRPV4 is required for crystal-induced inflammation.
  Zhou Lan, Lvyi Chen, Jing Feng, Zili Xie, Zhiyong Liu, Fang Wang, Peng Liu, Xueping Yue, Lixia Du, Yonghui Zhao, Pu Yang, Jialie Luo, Zhe Zhu, Xueming Hu, Liang Cao, P...> ;Annals of the Rheumatic Diseases. 2021 Aug 20
• 8 citations
  Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A.
  Corinne S. Wilson, Preeti Dohare, Shaina Orbeta, Julia W. Nalwalk, Yunfei Huang, Russell J. Ferland, Rajan Sah, Annalisa Scimemi, Alexander A. Mongin> ;FASEB Journal. 2021 Oct 1
• 68 citations
  Resident cardiac macrophages mediate adaptive myocardial remodeling
  Nicole R. Wong, Jay Mohan, Benjamin Kopecky, Shuchi Guo, Lixia Du, Jamison Leid, Guoshuai Feng, Inessa Lokshina, Oleksandr Dmytrenko, Hannah Luehmann, Geetika Bajpai, ...> ;Immunity. 2021 Sep 14
• 8 citations
  Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria
  , , , , , , , , , , , , , , , , , > ;JCI Insight. 2021 May 10
• 27 citations
  The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function.
  Ahmad F. Alghanem, Javier Abello, Joshua M Maurer, Ashutosh Kumar, Chau My Ta, Susheel K. Gunasekar, Urooj Fatima, Chen Kang, Litao Xie, Oluwaseun Adeola, Megan J Rike...> ;Elife. 2021 Feb 25
• 6 citations
  Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity.
  Daniel Turner, Chen Kang, P. Mesirca, Juan Hong, Matteo E. Mangoni, Alexey V. Glukhov, Rajan Sah> ;Frontiers in Cardiovascular Medicine. 2021 Aug 9
• 28 citations
  LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.
  Ping Li, Meiqin Hu, Ce Wang, Xinghua Feng, Zhuang Zhuang Zhao, Ying Yang, Nirakar Sahoo, Mingxue Gu, Yexin Yang, Shiyu Xiao, Rajan Sah, Timothy L. Cover, Janet Chou, R...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Nov 17
• 24 citations
  LRRC8A-dependent volume-regulated anion channels contribute to ischemia-induced brain injury and glutamatergic input to hippocampal neurons.
  Jing Jing Zhou, Yi Luo, Shao Rui Chen, Jian Ying Shao, Rajan Sah, Hui Lin Pan> ;Experimental Neurology. 2020 Oct 1
• 24 citations
  ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense.
  Derayvia Grimes, Ryan Johnson, Madeline Pashos, Celeste L. Cummings, Chen Kang, Georgia R. Sampedro, Eric Tycksen, Helen J. McBride, Rajan Sah, Clifford A. Lowell, Reg...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Sep 29
• 31 citations
  SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism.
  Ashutosh Kumar, Litao Xie, Chau My Ta, Antentor Othrell Hinton, Susheel K. Gunasekar, Rachel A Minerath, Karen Shen, Joshua M Maurer, Chad E. Grueter, E. Dale Abel, Gr...> ;Elife. 2020 Sep 15
• 49 citations
  Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell.
  Danusa Menegaz, D. Walker Hagan, Joana Almaça, Chiara Cianciaruso, Rayner Rodriguez-Diaz, Judith Molina, Robert M. Dolan, Matthew W. Becker, Petra C. Schwalie, Rita Na...> ;Nature Metabolism. 2019 Nov 1
• 12 citations
  Role of diabetes and insulin use in the risk of stroke and acute myocardial infarction in patients with atrial fibrillation: A Medicare analysis
  Amgad Mentias, Ghanshyam Palamaner Subash Shantha, Oluwaseun Adeola, Geoffrey D. Barnes, Bharat Narasimhan, Konstantinos C. Siontis, Deborah A. Levine, Rajan Sah, Mich...> ;American Heart Journal. 2019 Aug 1
• 11 citations
  SWELL signalling in adipocytes: can fat 'feel' fat?
  Susheel K. Gunasekar, Litao Xie, Rajan Sah> ;Adipocyte. 2019 May 21
• 59 citations
  SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia
  Chen Kang, Litao Xie, Susheel K. Gunasekar, Anil Mishra, Yanhui Zhang, Saachi Pai, Yiwen Gao, Ashutosh Kumar, Andrew W. Norris, Samuel B. Stephens, Rajan Sah> ;Nature Communications. 2018 Jan 25
• 12 citations
  Induction of adipose and hepatic SWELL1 expression is required for maintaining systemic insulin-sensitivity in obesity.
  Litao Xie, Yanhui Zhang, Susheel K. Gunasekar, Anil Mishra, Lei Cao, Rajan Sah> ;Channels. 2017 Oct 5
• 79 citations
  TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles
  Sunday A. Abiria, Grigory Krapivinsky, Rajan Sah, Ana Santa-Cruz, Dipayan Chaudhuri, Jin Zhang, Pichet Adstamongkonkul, Paul G. DeCaen, David E. Clapham> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 25
• Join now to see all