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Office
5912 Hartford Way
Brighton, MI 48116Phone+1 517-376-2006- Is this information wrong?
Summary
- Dr. Richard Messmann is a medical oncologist, biochemist, electrical and computer engineer and clinical research physician with over 25 years of experience in oncology drug development ranging from Phase I-III clinical studies. Dr. Messmann’s career focus is in the development of targeted diagnostic and therapeutic agents for treatment of various cancer indications.
After completing a medical oncology fellowship at the National Cancer Institute and obtaining an advanced degree in clinical trial management from Duke University, he served as Deputy Associate Director of the NIH/NCI’s Developmental Therapeutics Program (DTP). He has also held executive positions with Advanced Accelerator Applications (AAA, Novartis AG), Endocyte, Eli Lilly & Co., Michigan State University, ProNAi Therapeutics, Apexian Pharmaceuticals and Amgen Inc.
Dr. Messmann's clinical leadership of the VISION Phase 3 study of Pluvicto (177Lu-PSMA-617) resulted in the regulatory approval of the first successfully developed radio-therapeutic and radio-diagnostic for use in men with advanced metastatic castrate-resistant prostate cancer. The trial results were presented at the ASCO 2021 plenary session with a concurrent publication in the New England Journal of Medicine (https://www.nejm.org/doi/full/10.1056/nejmoa2107322).
He is currently the Executive Medical Director for Global Development of Xaluritamig (AMG 509), an Anti-STEAP1 XmAb 2+1 T-cell therapy against advanced-stage prostate cancer, early details of which were presented at the 2023 Madrid meeting of the European Society of Medical Oncology.
Education & Training
- National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1997 - 2000
- Sparrow Hospital/Michigan State UniversityResidency, Internal Medicine, 1995 - 1997
- University of Michigan Health SystemResidency, Anesthesiology, 1994 - 1995
- MedStar Health/Georgetown University HospitalResidency, Anesthesiology, 1993 - 1993
- Sparrow Hospital/Michigan State UniversityInternship, Internal Medicine, 1991 - 1992
- Wayne State University School of MedicineClass of 1991
Certifications & Licensure
- MI State Medical License 1995 - 2026
- VA State Medical License 1993 - 2002
Clinical Trials
- Safety and Tolerability Study of FolateImmune in Combination With Cytokines in Patients With Refractory or Metastatic Cancer Start of enrollment: 2005 Sep 01
- Study of EC0225 for the Treatment of Refractory or Metastatic Tumors Start of enrollment: 2007 Feb 01
- A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma Start of enrollment: 2007 Jun 01
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Publications & Presentations
PubMed
- 3 citationsA Phase 2 Study of PNT2258 for Treatment of Relapsed or Refractory B-Cell MalignanciesWael A. Harb, Nehal Lakhani, Richard A. Messmann, Barbara Klencke, Ayad Al-Katib> ;Clinical Lymphoma, Myeloma & Leukemia. 2021 Jul 23
- 761 citationsLutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.Oliver Sartor, Johann S. de Bono, Kim N. Chi, Karim Fizazi, Ken Herrmann, Kambiz Rahbar, Scott T. Tagawa, Luke T. Nordquist, Nitin Vaishampayan, Ghassan El-Haddad, Cha...> ;The New England Journal of Medicine. 2021 Jun 23
- 50 citationsThe multifunctional APE1 DNA repair–redox signaling protein as a drug target in human diseaseRachel A. Caston, Silpa Gampala, Lee Armstrong, Richard A. Messmann, Melissa L. Fishel, Mark R. Kelley> ;Drug Discovery Today. 2021 Jan 1
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Press Mentions
- Apexian Pharmaceuticals Hires Richard Messmann, M.D. As Chief Medical OfficerOctober 31st, 2016
Professional Memberships
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