RobertCraigCastellinoMD

PubMed

• 3 citations
  Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas.
  Christopher M Rota, Alexander T Brown, Emily Addleson, Clara Ives, Ella Trumper, Kristine Pelton, Wei Pin Teh, Matthew J Schniederjan, Robert Craig Castellino, Sara Bu...> ;Neuro-Oncology Advances. 2022 Apr 13
• 3 citations
  Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care.
  Ryan J Summers, Sharon M Castellino, Christopher C Porter, Tobey J MacDonald, Gargi D Basu, Szabolcs Szelinger, Manoj K Bhasin, Thomas Cash, Alexis B Carter, Robert Cr...> ;JCO Precision Oncology. 2022 Apr 1
• 3 citations
  Ten-eleven translocation protein 1 modulates medulloblastoma progression.
  Hyerim Kim, Yunhee Kang, Yujing Li, Li Chen, Li Lin, Nicholas D. Johnson, Dan Zhu, M. Hope Robinson, Leon F. McSwain, Benjamin G. Barwick, Xianrui Yuan, Xinbin Liao, J...> ;Genome Biology. 2021 Apr 29
• 4 citations
  Phosphatase magnesium-dependent 1 δ (PPM1D), serine/threonine protein phosphatase and novel pharmacological target in cancer.
  Rita Nahta, Robert C. Castellino> ;Biochemical Pharmacology. 2021 Feb 1
• Correction: Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.
  Bridgette F Peake, Siobhan M Eze, Lily Yang, Robert C Castellino, Rita Nahta> ;Oncotarget. 2020 Nov 3
• HASH(0x3f080c0)
  Kadom, N.,Castellino, R. C.,Wolf, D. S.> ;AJNR Am J Neuroradiol. 2019 May 11
• 23 citations
  Inhibition of mutant PPM1D enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
  Mwangala P. Akamandisa, Kai Nie, Rita Nahta, Dolores Hambardzumyan, Robert C. Castellino> ;Neuro-Oncology. 2019 Jun 10
• 6 citations
  High-Grade Gliomas in Children with Neurofibromatosis Type 1: Literature Review and Illustrative Cases.
  C.D. Spyris, Robert C. Castellino, Matthew Schniederjan, Nadja Kadom> ;AJNR. American Journal of Neuroradiology. 2019 Feb 1
• 1 citations
  Atoh1/MATH1 Adds Up to Ciliogenesis for Transducing SHH Signaling in the Cerebellum.
  Robert C. Castellino, Anna Kenney> ;Developmental Cell. 2019 Jan 28
• 26 citations
  Clinical responses of patients with diffuse leptomeningeal glioneuronal tumors to chemotherapy.
  Dolly Aguilera, Robert C. Castellino, Anna J. Janss, Mathew Schniederjan, Renee McNall, Tobey J. MacDonald, Claire Mazewski> ;Child's Nervous System. 2018 Feb 1
• 13 citations
  Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.
  Bridgette F Peake, Siobhan M Eze, Lily Yang, Robert C Castellino, Rita Nahta> ;Oncotarget. 2017 Nov 7
• 20 citations
  WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma
  Jing Wen, Juhyun Lee, Anshu Malhotra, Rita Nahta, Amanda R. Arnold, Meghan C. Buss, Briana D. Brown, Caroline Maier, Anna Kenney, Marc Remke, Vijay Ramaswamy, Michael ...> ;Oncogene. 2016 Oct 20
• 2 citations
  PPM1D/WIP1 in medulloblastoma.
  Mwangala P. Akamandisa, Rita Nahta, Robert C. Castellino> ;Oncoscience. 2016 Sep 3
• 37 citations
  Successful Retreatment of a Child with a Refractory Brainstem Ganglioglioma with Vemurafenib.
  Dolly Aguilera, Anna J. Janss, Claire Mazewski, Robert C. Castellino, Matthew Schniederjan, Laura L. Hayes, Barunashish Brahma, Lauren Fogelgren, Tobey J. MacDonald> ;Pediatric Blood & Cancer. 2016 Mar 1
• 42 citations
  Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression
  Rita Nahta, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Rafaela Andrade-Vieira, Sarah N Bay, Dustin G. Brown, Gloria M. Calaf, Robert C. Castellino, Karine A. Coh...> ;Carcinogenesis. 2015 Jun 1
• 172 citations
  Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: The challenge ahead
  William H. Goodson, Leroy Lowe, David O. Carpenter, Michael Gilbertson, Abdul Manaf Ali, Adela Lopez de Cerain Salsamendi, Ahmed Lasfar, Amancio Carnero, Amaya Azqueta...> ;Carcinogenesis. 2015 Jun 1
• 41 citations
  The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants
  Meghan C. Buss, Marc Remke, Juhyun Lee, Khanjan Gandhi, Matthew Schniederjan, Marcel Kool, Paul A. Northcott, Stefan M. Pfister, Michael D. Taylor, Robert C. Castellino> ;Oncogene. 2015 Feb 26
• 34 citations
  Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src...
  Eduardo Sanabria-Figueroa, Siobhan M. Donnelly, Kevin Chu Foy, Meghan C. Buss, Robert C. Castellino, Elisavet Paplomata, LaTonia Taliaferro-Smith, Pravin T. P. Kaumaya...> ;Molecular Pharmacology. 2015 Feb 1
• 7 citations
  Response of subependymal giant cell astrocytoma with spinal cord metastasis to everolimus.
  Dolly Aguilera, Robert Flamini, Claire Mazewski, Matthew Schniederjan, Laura L. Hayes, William Boydston, Robert C. Castellino, Tobey J. MacDonald> ;Journal of Pediatric Hematology/oncology. 2014 Oct 1
• 49 citations
  The rationale for targeted therapies in medulloblastoma
  Tobey J. MacDonald, Dolly Aguilera, Robert C. Castellino> ;Neuro-Oncology. 2014 Jan 1
• 21 citations
  MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1
  Sylvia S. Gayle, Robert C. Castellino, Meghan C. Buss, Rita Nahta> ;Current Medicinal Chemistry. 2013 May 31
• 52 citations
  Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience
  Dolly Aguilera, Claire Mazewski, Jason Fangusaro, Tobey J. MacDonald, Rene Y. McNall-Knapp, Laura L. Hayes, Sungjin Kim, Robert C. Castellino> ;Child's Nervous System. 2013 Jan 8
• 16 citations
  HDM2 promotes WIP1-mediated medulloblastoma growth.
  Meghan C. Buss, Tracy Ann Read, Matthew Schniederjan, Khanjan Gandhi, Robert C. Castellino> ;Neuro-Oncology. 2012 Apr 1
• 39 citations
  Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.
  Thamara J. Abouantoun, Robert C. Castellino, Tobey J. MacDonald> ;Journal of Neuro-Oncology. 2011 Jan 1
• 40 citations
  Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma
  Robert C. Castellino, Benjamin G. Barwick, Matthew Schniederjan, Meghan C. Buss, Oren J. Becher, Dolores Hambardzumyan, Tobey J. MacDonald, Daniel J. Brat, Donald L. D...> ;Plos One. 2010 May 26
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