ShaliniShenoyMD(She/Her)

Pediatric Hematology & Oncology • Saint Louis, MO

Pediatric Hematologic Oncology

Professor of Pediatrics, Director, Pediatric Transplant & Cellular Therapy, Washington University School of Medicine

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Office
1 Childrens Pl
Saint Louis, MO 63110
Phone+1 314-454-6018

Fax+1 314-454-2780
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Pediatric Hematology/Oncology, 1992 - 1995
Louisiana State University School of MedicineResidency, Pediatrics, 1991 - 1991
Kasturba Medical College ManipalClass of 1981

Certifications & Licensure

MO State Medical License 1994 - 2025
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101) Start of enrollment: 2003 Nov 01
Completed
Phase 3
Peripheral Blood Stem Cell Transplant vs Bone Marrow Transplant in Individuals With Hematologic Cancers (BMT CTN 0201) Start of enrollment: 2004 Jan 01
Completed
Phase 3
Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302) Start of enrollment: 2005 Sep 01
Completed
Phase 2
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) Start of enrollment: 2006 Dec 01
Completed
Phase 3
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) Start of enrollment: 2008 Aug 01
Completed
Phase 2
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases Start of enrollment: 2001 Dec 01
Recruiting
Phase 1, Phase 2
Stem Cell Related Donor Safety Study Start of enrollment: 2010 Jan 01
Completed
Reduced Intensity Transplant Conditioning Regimen for Severe Thalassemia Start of enrollment: 2010 Jan 01
Completed
Phase 2
Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) Start of enrollment: 2010 Apr 01
Completed
Phase 2, Phase 3
Natural History Study of SCID Disorders Start of enrollment: 2010 Sep 02
Enrolling by invitation
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Patients Treated for SCID (1968-Present) Start of enrollment: 2011 May 15
Enrolling by invitation
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) Start of enrollment: 2011 Oct 01
Recruiting
MRD Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia Start of enrollment: 2011 Oct 01
Completed
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease Start of enrollment: 2012 Jan 01
Active, not recruiting
Phase 2
Patients Treated for Wiskott-Aldrich Syndrome (WAS) Since 1990 Start of enrollment: 2014 Feb 02
Completed
Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995 Start of enrollment: 2014 Jun 01
Enrolling by invitation
Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) Start of enrollment: 2017 Oct 03
Active, not recruiting
Phase 2
Roles: Contact
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders Start of enrollment: 2017 Mar 20
Recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV) Start of enrollment: 2018 Nov 01
Recruiting
Phase 2
Roles: Contact
Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors Start of enrollment: 2019 Apr 03
Active, not recruiting
Roles: Principal Investigator, Contact
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis Start of enrollment: 2022 Mar 30
Recruiting
Phase 2
Roles: Contact, Principal Investigator
Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection Start of enrollment: 2018 Nov 01
Recruiting
Phase 2
Roles: Contact
EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection Start of enrollment: 2020 Jul 07
Recruiting
Phase 2
Roles: Contact
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs) Start of enrollment: 2020 Jul 01
Recruiting
Phase 1, Phase 2
Roles: Contact
NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors Start of enrollment: 2020 Dec 08
Recruiting
Not Applicable
Roles: Contact
A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) Start of enrollment: 2023 Jan 25
Recruiting
Phase 3
Roles: Contact
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation Start of enrollment: 2019 Mar 22
Recruiting
Phase 2
Roles: Contact
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Publications & Presentations

PubMed

The Adverse Event Landscape of Stem Cell Transplant: Evidence for aGVHD Driving Early Transplant Associated Toxicities.
Takuto Takahashi, Benjamin Watkins, Brandi Bratrude, Donna Neuberg, Kyle Hebert, Kayla Betz, Alison Yu, Sung W Choi, Jeffrey Davis, Christine Duncan, Roger Giller, Mic...> ;Transplantation and Cellular Therapy. 2024 Apr 6
Hyperthyroidism following transplantation and SARS-CoV-2 exposure.
Mennatallah Elnaggar, Shalini Shenoy> ;Pediatric Blood & Cancer. 2023 Dec 1
Mixed donor chimerism following stem cell transplantation for sickle cell disease.
Niketa C Shah, Hemalatha G Rangarajan, Alexander Ngwube, Shalini Shenoy> ;Current Opinion in Hematology. 2023 Nov 1
1 citations
Children's Oncology Group's 2023 blueprint for research: Cellular therapy and stem cell transplantation.
Carrie L Kitko, Catherine M Bollard, Mitchell S Cairo, Joseph Chewning, Terry J Fry, Michael A Pulsipher, Shalini Shenoy, Donna A Wall, John E Levine> ;Pediatric Blood & Cancer. 2023 Sep 1
7 citations
Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from...
Thakar, M., Logan, B., Puck, J., Dunn, E., Buckley, R., Cowan, M., O'Reilly, R., Kapoor, N., Satter, L., Pai, S., Heimall, J., Chandra, S., Ebens, C., Chellapandian, D...> ;Lancet. 2023 Jul 8
1 citations
Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events.
Takuto Takahashi, Mahmoud Al-Kofahi, Mutaz Jaber, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Alison Yu, Donna S Neuberg, Sung W Choi, Jeffrey Davis, Christine Dunc...> ;Blood. 2023 Aug 24
70 citations
The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
Ghayas C Issa, Ibrahim Aldoss, John DiPersio, Branko Cuglievan, Richard Stone, Martha Arellano, Michael J Thirman, Manish R Patel, David S Dickens, Shalini Shenoy, Nee...> ;Nature. 2023 Mar 1
2 citations
Organ function indications and potential improvements following curative therapy for sickle cell disease.
Monica L Hulbert, Allison A King, Shalini Shenoy> ;Hematology. American Society of Hematology. Education Program. 2022 Dec 9
Correction to: CD34-selected stem cell boost as therapy for late graft rejection following allogeneic transplantation for sickle cell disease.
Hemalatha G Rangarajan, Sara A Crowell, Alison S Towerman, Shalini S Shenoy> ;Bone Marrow Transplantation. 2022 Dec 1
2 citations
CD34-selected stem cell boost as therapy for late graft rejection following allogeneic transplantation for sickle cell disease.
Hemalatha G Rangarajan, Sara A Crowell, Alison S Towerman, Shalini S Shenoy> ;Bone Marrow Transplantation. 2022 Oct 1
1 citations
Significant improvement of child physical and emotional functioning after familial haploidentical stem cell transplant.
Susan K Parsons, Angie Mae Rodday, Ruth Ann Weidner, Erin Morris, Suzanne Braniecki, Shalini Shenoy, Julie-An Talano, Theodore B Moore, Anne Panarella, Allyson Flower,...> ;Bone Marrow Transplantation. 2022 Apr 1
Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease.
Yaya Chu, Julie-An Talano, Lee Ann Baxter-Lowe, James W Verbsky, Erin Morris, Harshini Mahanti, Janet Ayello, Carolyn Keever-Taylor, Bryon Johnson, Rona S Weinberg, Qi...> ;Frontiers in Immunology. 2022 Jan 1
10 citations
Effect of Aging and Predonation Comorbidities on the Related Peripheral Blood Stem Cell Donor Experience: Report from the Related Donor Safety Study.
Pulsipher, M. A., Pulsipher, M. A., Pulsipher, M. A., Pulsipher, M. A., Logan, B. R., Logan, B. R., Logan, B. R., Logan, B. R., Chitphakdithai, P., Chitphakdithai, P.,...> ;Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2018 Nov 14
12 citations
Related peripheral blood stem cell donors experience more severe symptoms and less complete recovery at 1-year compared to unrelated donors.
Pulsipher, M. A., Pulsipher, M. A., Pulsipher, M. A., Logan, B. R., Logan, B. R., Logan, B. R., Kiefer, D. M., Kiefer, D. M., Kiefer, D. M., Chitphakdithai, P., Chitph...> ;Haematologica. 2018 Nov 2
Hematopoietic stem cell transplantation for sickle cell disease: Progress and challenges.
Hulbert, M. L.,Shenoy, S.> ;Pediatr Blood Cancer. 2018 May 26
Reduced intensity conditioning for hematopoietic cell transplant for HLH and primary immune deficiencies: BMT CTN 1204.
Allen, C.,Marsh, R.,Dawson, P.,Bollard, C. M.,Shenoy, S.,Roehrs, P.,Hanna, R.,Burroughs, L.,Kean, L.,Talano, J. A.,Schultz, K. R.,Pai, S. Y.,Baker, K. S.,Andolina, J. ...> ;Blood. 2018 Jul 13
Outcomes of measurable residual disease in pediatric acute myeloid leukemia pre- and post-hematopoietic stem cell transplant: validation of difference from normal flow...
Jacobsohn, D. A.,Loken, M. R.,Fei, M.,Adams, A.,Brodersen, L. E.,Logan, B. R.,Ahn, K. W.,Shaw, B. E.,Kletzel, M.,Olszewski, M.,Khan, S.,Meshinchi, S.,Keating, A.,Harri...> ;Biol. Blood Marrow Transplant.. 2018 Jun 23
Early Identification of Barriers and Facilitators to Self-Management Behaviors in Pediatric Patients With Sickle Cell Disease to Minimize Hematopoietic Cell Transplant...
Schulz, G. L.,Foster, R. H.,Kennedy Lang, V.,Towerman, A.,Shenoy, S.,Lauer, B. A.,Molzon, E.,Holtmann, M.> ;J Pediatr Oncol Nurs. 2018 Mar 27
Unrelated Donor Transplantation in Children with Thalassemia Using Reduced Intensity Conditioning - the URTH Trial.
Shenoy, S.,Walters, M. C.,Ngwube, A.,Soni, S.,Jacobsohn, D.,Chaudhury, S.,Grimley, M.,Chan, K.,Haight, A.,Kasow, K. A.,Parikh, S.,Andreansky, M.,Connelly, J.,Delgado, ...> ;Biol. Blood Marrow Transplant.. 2018 Jan 29
Unrelated Umbilical Cord Blood Transplantation for Sickle Cell Disease Following Reduced Intensity Conditioning: Results of a Phase I Trial.
Abraham, A.,Cluster, A.,Jacobsohn, D.,Delgado, D.,Hulbert, M. L.,Kukadiya, D.,Murray, L.,Shenoy, S.> ;Biol. Blood Marrow Transplant.. 2017 Jun 05
Brincidofovir for Asymptomatic Adenovirus Viremia in Pediatric and Adult Allogeneic Hematopoietic Cell Transplant Recipients: A Randomized Placebo-Controlled Phase II ...
Monica Bhatia, Shalini Shenoy, Angela Smith> ;Biology of Blood and Marrow Transplantation. 2017 Jan 10
Long-Term Follow-up After Reduced Intensity Conditioning and Stem Cell Transplantation for Childhood Non-Malignant Disorders
Gregory A Hale, Sonali Chaudhury, Lisa M Madden, Paul Haut, Michael A Pulsipher, Robert J Hayashi, Shalini Shenoy, Kimberly A Kasow, Andrew Gilman> ;Biology of Blood and Marrow Transplantation. 2016 May 11
Umbilical cord blood: an evolving stem cell source for sickle cell disease transplants.
Shenoy, S.> ;Stem Cells Transl Med. 2013 May
18 citations
An outbreak of extended spectrum beta-lactamase producing Klebsiella pneumoniae in a neonatal intensive care unit.
Shalini Shenoy, Ashwini Hegde, R M Saldanha Dominic, Saritha Kamath, N Arvind> ;Indian Journal of Pathology & Microbiology. 2007 Jul 1
110 citations
A novel reduced-intensity stem cell transplant regimen for nonmalignant disorders
Shalini Shenoy, William Grossman, John F. DiPersio, Lolie Yu, David B. Wilson, Y.J. Barnes, T. Mohanakumar, Aarati Rao, Robert J. Hayashi> ;Bone Marrow Transplantation. 2005 Feb 1
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Journal Articles

Late Effects Screening Guidelines after Hematopoietic Cell Transplantation (HCT) for Hemoglobinopathy: Consensus Statement from the Second Pediatric Blood and Marrow T...
Shenoy S, Gaziev J, Angelucci E, King A, Bhatia M, Smith A, Bresters D, Haight AE, Duncan CN, de la Fuente J, Dietz AC, Baker KS, Pulsipher MA, Walters MC., Biology of Blood and Marrow Transplant
Reduced Intensity Conditioning for Hematopoietic Cell Transplant for HLH and Primary Immune Deficiencies: BMT CTN 1204
Shalini Shenoy, K Scott Baker, Elizabeth O Stenger, Mary Eapen, Carl Allen, Lauri Burroughs, Philip Roehrs, Catherine M Bollard, Rabi Hanna, Jeffrey R Andolina, James ..., Blood

Hospital Affiliations

St. Louis Children's HospitalSaint Louis, Missouri