SharonASinghMD

Pediatric Hematology & Oncology • Ann Arbor, MI

Michigan Medicine, University of Michigan

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Office
1500 E Medical Center Dr
C.S. Mott Children’s Hospital
Ann Arbor, MI 48109
Phone+1 734-936-9814
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Education & Training

Zucker School of Medicine at Hofstra/Northwell at Cohen Children's Medical CenterFellowship, Pediatric Hematology/Oncology, 2005 - 2008
Zucker School of Medicine at Hofstra/Northwell at Cohen Children's Medical CenterResidency, Pediatrics, 2001 - 2004
Icahn School of Medicine at Mount SinaiClass of 2001

Certifications & Licensure

MI State Medical License 2016 - 2026
NY State Medical License 2004 - 2017
NJ State Medical License 2004 - 2005
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Publications & Presentations

PubMed

6 citations
Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Lei Yu, Greggory Myers, Emily Schneider, Yu Wang, Raven Mathews, Kim Chew Lim, David Siemieniak, Vi Tang, David Ginsburg, Ginette Balbin-Cuesta, Sharon A Singh, Pongpo...> ;Blood Advances. 2022 Jun 14
3 citations
A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia
Lei Yu, Philippe Lemay, Alexander V. Ludlow, Marie-Claude Guyot, Morgan Jones, Fatma Mohamed, Ghazi-Abdullah Saroya, Christopher Panaretos, Emily Schneider, Yu Wang, G...> ;Blood Advances. 2021 Oct 26
13 citations
An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Lei Yu, Greggory Myers, Chia Jui Ku, Emily Schneider, Yu Wang, Sharon A. Singh, Natee Jearawiriyapaisarn, Andrew White, Takashi Moriguchi, Rami Khoriaty, Masayuki Yama...> ;Blood. 2021 Nov 4
5 citations
Buprenorphine for Chronic Pain in a Pediatric Patient With Sickle-Cell Disease.
Madison N. Irwin, William Gunther, Patricia Keefer, D'Anna Saul, Sharon A. Singh, Jennifer Wright, Michael A. Smith> ;Journal of Pain and Symptom Management. 2021 Apr 14
2 citations
Epigenetic activities in erythroid cell gene regulation
Yu Wang, Lei Yu, James Douglas Engel, Sharon A. Singh> ;Seminars in Hematology. 2021 Jan 1
1 citations
The Use of B-Cell Polysome Profiling to Validate Novel RPL5 (uL18) and RPL26 (uL24) Variants in Diamond-Blackfan Anemia.
Alexander V. Ludlow, Nicholas George, Megan Glassford, Katie Udenberg Md, Mark C. Hannibal, Carla Schwalm, Katie Scott Md, Thomas L. Rothstein, Sharon A. Singh> ;Journal of Pediatric Hematology/oncology. 2021 Apr 1
9 citations
What is the future of patient-reported outcomes in sickle-cell disease?
Sharon A. Singh, Nitya Bakshi, Prashant Mahajan, Claudia R. Morris> ;Expert Review of Hematology. 2020 Oct 15
10 citations
Hb Adana (HBA2 or HBA1: c.179G > A) and alpha thalassemia: Genotype-phenotype correlation.
Sharon A. Singh, Susmita N. Sarangi, Abena Appiah-Kubi, Peihong Hsu, W. Byron Smith, Patrick G. Gallagher, Bertil Glader, David H.K. Chui> ;Pediatric Blood & Cancer. 2018 Sep 1
65 citations
Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
Brian M. Dulmovits, Abena Appiah-Kubi, Julien Papoin, John Hale, Mingzhu He, Yousef Al-Abed, Sebastien Didier, Michael Gould, Sehba Husain-Krautter, Sharon A. Singh, K...> ;Blood. 2016 Mar 17
41 citations
Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial
John C. Wood, Alan R. Cohen, Sara L. Pressel, Banu Aygun, Hamayun Imran, Lori Luchtman-Jones, Alexis A. Thompson, Beng Fuh, William H. Schultz, Barry R. Davis, Russell...> ;British Journal of Haematology. 2016 Jan 1
31 citations
p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.
Sharon A. Singh, Tracie A. Goldberg, Adrianna Henson, Sehba Husain-Krautter, Abdallah Nihrane, Lionel Blanc, Steven R. Ellis, Jeffrey M. Lipton, Johnson M. Liu> ;Plos One. 2014 Feb 18
10 citations
Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome
Adrianna Vlachos, Jason E. Farrar, Eva Atsidaftos, Ellen Muir, Anupama Narla, Thomas C. Markello, Sharon A. Singh, Michael Landowski, Hanna T. Gazda, Lionel Blanc, Joh...> ;Blood. 2013 Oct 3
10 citations
Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman–Diamond syndrome protein SBDS
Gülay Sezgin, Adrianna Henson, Abdallah Nihrane, Sharon A. Singh, Max M. Wattenberg, Pascale Alard, Steven R. Ellis, Johnson M. Liu> ;Pediatric Blood & Cancer. 2013 Feb 1
13 citations
Breast cancer in a case of Shwachman Diamond syndrome.
Sharon A. Singh, Adrianna Vlachos, Nora J. Morgenstern, Ihsane Ouansafi, Wan Ip, Johanna M. Rommens, Peter R. Durie, Akiko Shimamura, Jeffrey M. Lipton> ;Pediatric Blood & Cancer. 2012 Nov 1
33 citations
Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities
Banu Aygun, Lisa Wruck, William H. Schultz, Brigitta U. Mueller, Clark Brown, Lori Luchtman-Jones, Sherron M. Jackson, Rathi V. Iyer, Zora R. Rogers, Sharada A. Sarnai...> ;American Journal of Hematology. 2012 Apr 1
34 citations
Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyurea.
Sharon A. Singh, Anastassios C. Koumbourlis, Banu Aygun> ;Pediatric Blood & Cancer. 2008 Jun 1
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Abstracts/Posters

Mutation of Murine Rpl5 reveals a New Model for Diamond Blackfan Anemia Characterized By Defective Erythropoiesis
Sharon A Singh, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019