StephenSLefrakMD

Pulmonology • Saint Louis, MO

Critical Care Medicine, Pleural Disease

Professor, Internal Medicine, Washington University School of Medicine

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Office
4921 Parkview Pl
8th Floor
Saint Louis, MO 63110
Phone+1 314-454-8917

Fax+1 314-454-7524
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Education & Training

New York Presbyterian Hospital (Columbia Campus)Residency, Internal Medicine, 1969 - 1970
SUNY Health Science Center at BrooklynFellowship, Pulmonary Disease and Critical Care Medicine, 1968 - 1969
Boston University Medical CenterResidency, Internal Medicine, 1965 - 1968
State University of New York Downstate Medical Center College of MedicineClass of 1965

Certifications & Licensure

MO State Medical License 1972 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Top MD Consumers Checkbook

Publications & Presentations

PubMed

7 citations
Systematic sarcoidosis with severe involvement of the upper respiratory tract.
Lefrak S, Di Benedetto R> ;The American Review of Respiratory Disease. 2015 May 14
52 citations
In vivo detection of acinar microstructural changes in early emphysema with (3)He lung morphometry.
James D. Quirk, Barbara A. Lutey, David S. Gierada, Jason C. Woods, Robert M. Senior, Stephen S. Lefrak, Alexander L. Sukstanskii, Mark S. Conradi, Dmitriy A. Yablonskiy> ;Radiology. 2011 Sep 1
20 citations
Tainted eponyms in medicine: the “Clara” cell joins the list
Alexander Woywodt, S. Lefrak, Eric L. Matteson> ;The European Respiratory Journal. 2010 Oct 1
4 citations
Accuracy of Emphysema Quantification Performed With Reduced Numbers of CT Sections
Thomas K. Pilgram, James D. Quirk, Andrew J. Bierhals, Roger D. Yusen, Stephen S. Lefrak, Joel D. Cooper, David S. Gierada> ;AJR. American Journal of Roentgenology. 2010 Mar 1
53 citations
Hyperpolarized 3He MR Imaging: Physiologic Monitoring Observations and Safety Considerations in 100 Consecutive Subjects
Barbara A. Lutey, Stephen S. Lefrak, Jason C. Woods, Tariq Tanoli, James D. Quirk, Adil Bashir, Dmitriy A. Yablonskiy, Mark S. Conradi, Seth T. Bartel, Thomas K. Pilgr...> ;Radiology. 2008 Aug 1
11 citations
Outcomes After Unilateral Lung Volume Reduction
Bryan F. Meyers, Parvez K. Sultan, Tracey J. Guthrie, Stephen S. Lefrak, Gail E. Davis, G. Alexander Patterson, Joel D. Cooper, Roger D. Yusen> ;The Annals of Thoracic Surgery. 2008 Jul 1
10 citations
Freidrich Wegener: The Past and Present
Stephen S. Lefrak, Eric L. Matteson> ;Chest. 2007 Dec 1
16 citations
Transpleural ventilation of explanted human lungs
Cliff Khuat Chye Choong, Peter T. Macklem, John A. Pierce, Stephen S. Lefrak, Jason C. Woods, Mark S. Conradi, Dmitriy A. Yablonskiy, James C. Hogg, Kimiaki Chino, Joe...> ;Thorax. 2007 Apr 5
reader's response to the webcast video editorial entitled "the international code of medical ethics of the World Medical Association".
Stephen S. Lefrak> ;Medgenmed. 2005 Feb 1
28 citations
3He diffusion MRI of the lung.
Mark S. Conradi, Dmitriy A. Yablonskiy, Jason C. Woods, David S. Gierada, Richard E. Jacob, Yulin V. Chang, Cliff Khuat Chye Choong, A. L. Sukstanskii, Tariq Tanoli, S...> ;Academic Radiology. 2005 Nov 1
Integrating social and ethics-based aspects of medicine into physician education.
Ira J. Kodner, Stephen S Lefrak, Rebecca Dresser, Robert J. Rothbaum> ;Missouri Medicine. 2004 Sep 1
20 citations
Results of lung volume reduction surgery in patients meeting a National Emphysema Treatment Trial high-risk criterion
Bryan F. Meyers, Roger D. Yusen, Tracey J. Guthrie, G. Alexander Patterson, Stephen S. Lefrak, Gail E. Davis, Joel D. Cooper> ;The Journal of Thoracic and Cardiovascular Surgery. 2004 Mar 1
72 citations
A Prospective Evaluation of Lung Volume Reduction Surgery in 200 Consecutive Patients
Roger D. Yusen, Stephen S. Lefrak, David S. Gierada, Gail E. Davis, Bryan F. Meyers, G. Alexander Patterson, Joel D. Cooper> ;Chest. 2003 Apr 1
132 citations
Long-term outcome of bilateral lung volume reduction in 250 consecutive patients with emphysema
Anna Maria Ciccone, Bryan F. Meyers, Tracey J. Guthrie, Gail E. Davis, Roger D. Yusen, Stephen S. Lefrak, G. Alexander Patterson, Joel D. Cooper> ;The Journal of Thoracic and Cardiovascular Surgery. 2003 Mar 1
Surgery for emphysema.
Joel D Cooper, Stephen S Lefrak> ;The New England Journal of Medicine. 2002 Mar 14
278 citations
Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI
Dmitriy A. Yablonskiy, Alexander L. Sukstanskii, Jason C. Leawoods, David S. Gierada, G. Larry Bretthorst, Stephen S. Lefrak, Joel D. Cooper, Mark S. Conradi> ;Proceedings of the National Academy of Sciences of the United States of America. 2002 Mar 5
98 citations
Repeatability of quantitative CT indexes of emphysema in patients evaluated for lung volume reduction surgery.
David S. Gierada, Roger D. Yusen, Thomas K. Pilgram, Lora Crouch, Richard M. Slone, Kyongtae T. Bae, Stephen S. Lefrak, Joel D. Cooper> ;Radiology. 2001 Aug 1
30 citations
Outcome of bilateral lung volume reduction in patients with emphysema potentially eligible for lung transplantation.
Bryan F. Meyers, Roger D. Yusen, Tracey J. Guthrie, Gail E. Davis, Mary S. Pohl, Stephen S. Lefrak, G. Alexander Patterson, Joel D. Cooper> ;The Journal of Thoracic and Cardiovascular Surgery. 2001 Jul 1
11 citations
Improved long-term survival seen after lung volume reduction surgery compared to continued medical therapy for emphysema.
Bryan F. Meyers, Roger D. Yusen, Stephen S. Lefrak, Joel D. Cooper> ;The Annals of Thoracic Surgery. 2001 Jun 1
239 citations
MR imaging of diffusion of 3He gas in healthy and diseased lungs
Brian Saam, Dmitriy A. Yablonskiy, Vikram D. Kodibagkar, Jason C. Leawoods, David S. Gierada, Joel D. Cooper, Stephen S. Lefrak, Mark S. Conradi> ;Magnetic Resonance in Medicine. 2000 Aug 1
43 citations
Dynamic echo planar MR imaging of lung ventilation with hyperpolarized (3)He in normal subjects and patients with severe emphysema.
David S. Gierada, Brian Saam, Dmitriy A. Yablonskiy, Joel D. Cooper, Stephen S. Lefrak, Mark S. Conradi> ;NMR in Biomedicine. 2000 Jun 1
45 citations
Patient Selection for Lung Volume Reduction Surgery: An Objective Model Based on Prior Clinical Decisions and Quantitative CT Analysis
David S. Gierada, Roger D. Yusen, Ian A. Villanueva, Thomas K. Pilgram, Richard M. Slone, Stephen S. Lefrak, Joel D. Cooper> ;Chest. 2000 Apr 1
21 citations
Lung-reduction surgery: 5 years on
Joel D. Cooper, Stephen S. Lefrak> ;Lancet. 1999 Apr 1
49 citations
Outcome of Medicare patients with emphysema selected for, but denied, a lung volume reduction operation
Bryan F. Meyers, Roger D. Yusen, Stephen S. Lefrak, G. Alexander Patterson, Mary S. Pohl, Veronica J. Richardson, Joel D. Cooper> ;The Annals of Thoracic Surgery. 1998 Aug 1
45 citations
Perfusion scintigraphy in the evaluation for lung volume reduction surgery: correlation with clinical outcome.
S C Wang, Keith C. Fischer, Richard M. Slone, D S Gierada, Roger D. Yusen, Stephen S. Lefrak, Thomas K. Pilgram, Joel D. Cooper> ;Radiology. 1997 Oct 1
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