StevenGerardKernieMD

PubMed

• 1 citations
  Distinct microglial transcriptomic signatures within the hippocampus.
  Chintamen, S., Gaur, P., Vo, N., Bradshaw, E., Menon, V., Kernie, S.> ;Plos One. 2024 Jan 1
• Delphi Process for Validation of Fluid Treatment Algorithm for Critically Ill Pediatric Trauma Patients.
  Duron, V., Schmoke, N., Ichinose, R., Stylianos, S., Kernie, S., Dayan, P., Slidell, M., Stulce, C., Chong, G., Williams, R., Gosain, A., Morin, N., Nasr, I., Kudchadk...> ;The Journal of Surgical Research. 2024 Mar 1
• 3 citations
  Characterization of the responses of brain macrophages to focused ultrasound-mediated blood-brain barrier opening.
  Alina R Kline-Schoder, Sana Chintamen, Moshe J Willner, Melody R DiBenedetto, Rebecca L Noel, Alec J Batts, Nancy Kwon, Stergios Zacharoulis, Cheng-Chia Wu, Vilas Meno...> ;Nature Biomedical Engineering. 2023 Oct 19
• Traumatic Brain Injury-Induced Fear Generalization in Mice Involves Hippocampal Memory Trace Dysfunction and Is Alleviated by (R,S)-Ketamine.
  Josephine C McGowan, Liliana R Ladner, Claire X Shubeck, Juliana Tapia, Christina T LaGamma, Amanda Anqueira-González, Ariana DeFrancesco, Briana K Chen, Holly C Hunsb...> ;Biological Psychiatry. 2024 Jan 1
• 5 citations
  Building consensus for the medical management of children with moderate and severe acute spinal cord injury: a modified Delphi study.
  Travis S CreveCoeur, Nikita G Alexiades, Christopher M Bonfield, Douglas L Brockmeyer, Samuel R Browd, Jason Chu, Anthony A Figaji, Mari L Groves, Todd C Hankinson, Da...> ;Journal of Neurosurgery. Spine. 2023 Mar 17
• 3 citations
  Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury.
  Rishi R Agrawal, Delfina Larrea, Yimeng Xu, Lingyan Shi, Hylde Zirpoli, Leslie G Cummins, Valentina Emmanuele, Donghui Song, Taekyung D Yun, Frank P Macaluso, Wei Min,...> ;Cellular and Molecular Neurobiology. 2023 Jul 1
• 7 citations
  A Single-Centered Randomized Controlled Trial of Primary Pediatric Intensivists and Nurses.
  Jeffrey D Edwards, Erin P Williams, Elizabeth K Wagman, Brittany L McHale, Caryn T Malone, Steven G Kernie> ;Journal of Intensive Care Medicine. 2022 Dec 1
• 1 citations
  Risk Variants in the Exomes of Children With Critical Illness.
  Joshua E Motelow, Natalie C Lippa, Joseph Hostyk, Evin Feldman, Matthew Nelligan, Zhong Ren, Anna Alkelai, Joshua D Milner, Ali G Gharavi, Yingying Tang, David B Golds...> ;JAMA Network Open. 2022 Oct 3
• 13 citations
  Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice
  Tzong-Shiue Yu, Yacine Tensaouti, Elizabeth P. Stephanz, Sana Chintamen, Elizabeth E. Rafikian, Mu Yang, Steven G. Kernie> ;Communications Biology. 2021 Nov 18
• 68 citations
  Multisystem Inflammatory Syndrome in Children Associated With Coronavirus Disease 2019 in a Children's Hospital in New York City: Patient Characteristics and an Instit...
  Brian Jonat, Mark Gorelik, Alexis Boneparth, Andrew S Geneslaw, Philip Zachariah, Amee Shah, Larisa Broglie, Juan Duran, Kimberly D. Morel, Maria Zorrilla, Leanne Svob...> ;Pediatric Critical Care Medicine. 2021 Mar 1
• 10 citations
  Immune Regulation of Adult Neurogenic Niches in Health and Disease.
  Sana Chintamen, Fatima Imessadouene, Steven G. Kernie> ;Frontiers in Cellular Neuroscience. 2021 Jan 20
• 14 citations
  A Hybrid Model of Pediatric and Adult Critical Care During the Coronavirus Disease 2019 Surge: The Experience of Two Tertiary Hospitals in London and New York.
  Akash Deep, Philip Knight, Steven G. Kernie, Pam D'Silva, Brittany Sobin, T. Best, Maria Zorrilla, Lydia Carson, Bogdana Sabina Zoica, Danielle Ahn> ;Pediatric Critical Care Medicine. 2021 Feb 1
• 61 citations
  Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation
  Deependra Kumar, Iyo Koyanagi, Alvaro Carrier-Ruiz, Pablo Vergara, Sakthivel Srinivasan, Yuki Sugaya, Masatoshi Kasuya, Tzong-Shiue Yu, Kaspar E. Vogt, Masafumi Murata...> ;Neuron. 2020 Aug 5
• 386 citations
  Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City.
  Eva W. Cheung, Philip Zachariah, Mark Gorelik, Alexis Boneparth, Steven G. Kernie, Jordan S. Orange, Joshua D. Milner> ;JAMA. 2020 Jul 21
• 314 citations
  Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York.
  Philip Zachariah, Candace L Johnson, Katia C Halabi, Danielle Ahn, Anita Sen, Avital M. Fischer, Sumeet L. Banker, Mirna Giordano, Christina S. Manice, Rebekah Diamond...> ;JAMA Pediatrics. 2020 Oct 1
• 4 citations
  The Perioperative Services Response at a Major Children's Hospital During the Peak of the COVID-19 Pandemic in New York City.
  Steven Stylianos, Amy E Mesa-Jonassen, Craig T Albanese, Emile A. Bacha, Natalya Stark, Sarah Jane Guida, Dena Goffman, Lisa Saiman, Steven G. Kernie, Anil K. Lalwani,...> ;Annals of Surgery. 2020 May 22
• 14 citations
  Rapid exome sequencing in PICU patients with new-onset metabolic or neurological disorders.
  Abigail S. Carey, John P Schacht, Christine Umandap, David Fasel, Chunhua Weng, Joshua Cappell, Wendy K. Chung, Steven G. Kernie> ;Pediatric Research. 2020 Mar 27
• 17 citations
  Apolipoprotein E regulates the maturation of injury-induced adult-born hippocampal neurons following traumatic brain injury
  Yacine Tensaouti, Tzong-Shiue Yu, Steven G. Kernie> ;Plos One. 2020 Mar 2
• 6 citations
  Child Abuse Taking Its Toll on the Emotional Well-Being of Pediatricians.
  Mandy A O'Hara, Teresa A. McCann, Weijia Fan, Mariellen Lane, Steven G. Kernie, Susan L. Rosenthal> ;Clinical Pediatrics. 2020 Feb 18
• 4 citations
  Hyaluronidase reduced edema after experimental traumatic brain injury.
  Patricia M. Washington, Changhee Lee, Mary Kate R Dwyer, Elisa E. Konofagou, Steven G. Kernie, Barclay Morrison> ;Journal of Cerebral Blood Flow and Metabolism. 2020 Oct 1
• 37 citations
  Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes.
  Maria-Adelaide Micci, Balaji Krishnan, Elizabeth Bishop, Wen Ru Zhang, Jutatip Guptarak, Auston Cody Grant, Olga Zolochevska, Batbayar Tumurbaatar, Whitney Franklin, C...> ;Molecular Neurodegeneration. 2019 Jun 14
• 36 citations
  ApoE Regulates the Development of Adult Newborn Hippocampal Neurons.
  Yacine Tensaouti, Elizabeth P. Stephanz, Tzong-Shiue Yu, Steven G. Kernie> ;Eneuro. 2018 Jul 1
• 11 citations
  Assessment of Recovery Following Pediatric Traumatic Brain Injury.
  Julia C. Slovis, Nachi Gupta, Natasha Y. Li, Steven G. Kernie, Darryl K. Miles> ;Pediatric Critical Care Medicine. 2018 Apr 1
• Adult newborn neurons interfere with fear discrimination in a protocol-dependent manner.
  Tzong-Shiue Yu, Yacine Tensaouti, Zohaib M. Bagha, Rina Davidson, Ahleum Kim, Steven G. Kernie> ;Brain and Behavior. 2017 Aug 2
• 98 citations
  Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition
  Carolyn Hollands, Matthew K. Tobin, Michael Hsu, Kianna Musaraca, Tzong-Shiue Yu, Rachana Mishra, Steven G. Kernie, Orly Lazarov> ;Molecular Neurodegeneration. 2017 Sep 8
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Journal Articles

• Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City  
  Steven G Kernie, Joshua D Milner, JAMA
• Epidemiology, Clinical Features, and Disease Severity in Patients with Coronavirus Disease 2019 (COVID-19) in a Children’s Hospital in New York City, New York  
  Katia C Halabi, Anita I Sen, Sumeet L Banker, Mirna Giordano, Adam J Schweickert, Daniel B Fenster, Teresa A Mccann, Steven G Kernie, JAMA Pediatrics
• Opposing effects of alpha2-and Beta-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis  
  Jhaveri, D.J., Nanavaty, I., Prosper, B.W., Marathe, S., Husain, B.F., Kernie, S.G., Bartlett, P.F., and Vaidya, V.A., PLoS One, 1/1/2014
• Overexpression of vascular endothelial growth factor in the germinal matrix induces neurovascular proteases and intraventricular hemorrhage  
  Yang, D., Bauman, J.M., Sun, Y.Y., Tang M., Dunn, R.S., Akeson, A.L., Kernie, S.G., Kallapur, S., Lindquist, D.M., Huang, E.J., Potter, S.S., Liang, H.C., and Kuan, C.Y., Science Translational Medicine, 1/10/2013
• Conditional ablation of neuroprogenitor cells in adult mice impedes recovery of poststroke cognitive function and reduces synaptic connectivity in the perforant pathway  
  Sun, C., Sun, H., Wu, S., Lee, CC., Akamtsu, Y., Wang, R.K., Kernie, S.G., and Liu, J., The Journal of Neuroscience, 1/1/2013
• Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice  
  Raman, L., Kong, X., and Kernie, S.G., Neuroscience Letters, 1/1/2013
• Advances in Pediatric Neurocritical Care  
  Cappell, J. and Kernie, S.G., Pediatric Clinics of North America, 1/1/2013
• A restricted cell population propagates glioblastoma growth following chemotherapy  
  Chen, J., Li, Y., Yu, T.Z., McKay, R.M., Burns, D.K., Kernie, S.G., and Parada, L.F., Nature, 1/1/2012
• Thyroid hormone accelerates the differentiation of adult hippocampal progenitors  
  Kappor, R., Desouza, L.A., Nanavaty, I.N., Kernie, S.G., and Vaidya, V.A., Journal of Neuroendocrinology, 1/1/2012
• Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex  
  Goto, J., Talos, D.M., Klein, P., Qin, W., Chekaluk, Y.I., Anderl, S., Malinowska, I.A., DiNardo, A., Bronson, R.T., Chan, J.A., Vintners, H.V., Kernie, S.G., Jensen, ..., Proceedings of the National Academy of Sciences, 1/1/2011
• GltI and Glast negatively regulate calcium-dependent proliferation of hippocampal neural progenitor cells and are persistently upregulated after injury  
  Gilley, J.A. and Kernie, S.G., European Journal of Neuroscience, 1/1/2011
• Chronic hypoxia impairs murine hippocampal development and depletes the postnatal progenitor pool by attenuating mTOR signaling  
  Raman, L., Kong, X., Gilley, J.A. and Kernie, S.G., Pediatric Research, 1/1/2011
• Temporally specified genetic ablation of neurogenesis impairs cognitive recovery following traumatic brain injury  
  Blaiss, C.A., Yu, T.S., Zhang, G., Chen, J., Dimchev, G., Parada, L.F., Powell, C.M., and Kernie, S.G., Journal of Neuroscience, 1/1/2011
• Protecting the Future: Neuroprotective Strategies in the Pediatric Intensive Care Unit  
  Koch, J.D. and Kernie, S.G., Current Opinion in Pediatrics, 1/1/2011
• Age-related changes in the oligodendrocyte progenitor pool influence brain remodeling after injury  
  Wright, J., Zhang, G., Yu, TS. and Kernie, S.G., Developmental Neuroscience, 1/1/2010
• Forebrain Neurogenesis after Focal Ischemic and Traumatic Brain Injury  
  Kernie, S.G. and Parent, J.M., Neurobiology of Disease, 1/1/2010
• Traumatic brain injury-induced hippocampal neurogenesis requires activation of early nestin-expressing progenitors  
  Yu, T.S., Zhang, G., Liebl, D.J., and Kernie, S.G., Journal of Neuroscience, 1/1/2008
• The bHLH transcription factor Olig2 is critical for reactive astrocyte proliferation after cortical injury  
  Chen, Y., Miles, D.K., Hoang, T.N., Shi, J., Hurlock, E.C., Kernie, S.G., and Lu, Q.R., Journal of Neuroscience, 1/1/2008
• Hypoxic-ischemic injury activates early hippocampal stem/progenitor cells to replace vulnerable neuroblasts  
  Miles, D.K. and Kernie, S.G., Hippocampus, 1/1/2008
• Brief exposure to hyperoxia depletes the glial progenitor pool and impairs functional recovery following hypoxic-ischemic brain injury  
  Koch, J., Miles, D.K., Gilley, J., Yang, C.P., and Kernie, S.G., Journal of Cerebral Blood Flow and Metabolism, 1/1/2008
• EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis  
  Chumley, M., Catchpole, T., Silvany, R., Kernie, S.G., and Henkemeyer, M., Journal of Neuroscience, 1/1/2007
• Injury-induced neurogenesis in Bax-deficient mice: Evidence for regulation by voltage-gated potassium channels  
  Shi, J., Miles, D.K., Orr, B.A., Massa, S.M., and Kernie, S.G., European Journal of Neuroscience, 1/1/2007
• A critical role for dorsal progenitors in cortical myelination  
  Yue, T., Xian, K., Hurlock, E., Xin, M., Kernie, S.G., Parada, L.F., and Lu, Q. R., Journal of Neuroscience, 1/1/2006
• Differential expression of the four untranslated BDNF exons in the adult mouse brain  
  Malkovska, I., Kernie, S.G., and Parada, L.F., Journal of Neuroscience Research, 1/1/2006
• Brain Remodeling and Regeneration after Injury  
  Miles, D.M. and Kernie S.G., Progress in Brain Research, 1/1/2006
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Books/Book Chapters

• Endogenous Stem Cell-Based Brain Remodeling in Mammals 
  Chapter: Role of Neural Stem and Progenitor Cells in the Adaptation of the Brain to Injury. 
  Page 57 - 86Hong, S., Yu, T.Z., and Kernie, S.G.Editors: Junier and Kernie.Humana Press2014
• Rudolph's Pediatrics 
  Chapter: Management of Cerebral Edema and Elevated Intracranial Pressure. 
  Page 420 - 422Kernie, S.G.Editors: Rudolph, C..McGraw-Hill PublishingEdition 22nd,2011
• Encyclopedia of Neuroscience 
  Chapter: Inflammation in Neurodegenerative Disease and Injury. 
  Page 131 - 136Tansey, M.G. and Kernie, S.G.Editors: Squire LR.Academic Press, Oxford2009
• Pediatric Critical Care Medicine: Basic Science and Clinical Evidence 
  Chapter: Intracranial Hypertension. 
  Page 902 - 916Kernie, S.G. and Lehman S.M.Editors: Wheeler, Wong, and Shanley.Springer-Verlag Publishing, Inc., London, UKEdition 1st,2007
• Neurobiology of Mental Illness 
  Chapter: Overview of Brain Development. 
  Rubenstein, J.L.R. and Kernie, S.G.Editors: Charney and Nestler.2004
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Lectures

• Neurosurgery Grand Rounds: "Self-repair After Traumatic Brain Injury" 
  Columbia University Medical Center, New York, NY - 1/30/2014
• Pediatric Critical Care Grand Rounds: "Mechanisms of Self-repair After Traumatic Brain Injury" 
  Children's Hospital Central California, Madera, CA - 1/18/2014
• "ICU Management of Severe Brain Injury in Children", Invited Speaker 
  Beijing Children's Hospital, Beijing, China - 1/28/2013
• Neurology Grand Rounds: "Mechanisms of Self-repair After Traumatic Brain Injury" 
  Neurological Institute of New York, Columbia University Medical Center, New York, NY - 1/17/2013
• Pediatric Grand Rounds: "The Role of Endogenous Neural Stem Cells in Recovery After Brain Injury" 
  Monroe Carell Jr. Children's Hospital, Vanderbilt, Medical Center, Nashville, TN - 1/9/2013
• "Genetic Modeling of Acquired Brain Disease" (Invited Seminar Speaker) 
  Department of Cell Biology, New York Medical College, Valhalla, NY - 1/6/2013
• Pediatric Grand Rounds: "Advances in Pediatric Traumatic Brain Injury" 
  Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY - 1/6/2013
• "Activation of Hippocampal Stem Cells Following Injury" 
  Washington, DC - 1/5/2013
• Physical Medicine and Rehabilitation Grand Rounds: "Mechanisms of Self-repair After Brain Injury" 
  Columbia University Medical Center, New York, NY - 1/1/2013
• "The Relevance of Hippocampal Neurogenesis to Human Brain Injury" 
  Wichita State University, Wichita, KS - 1/30/2012
• "Advances in Pediatric Traumatic Brain Injury" 
  Columbia University Medical Center, New York, NY - 1/24/2012
• Pediatric Grand Rounds: "Genetic Modeling of Acquired Brain Disease" 
  Columbia University Medical Center, New York, NY - 1/14/2012
• Pediatric Grand Rounds: "Hypoxic-ischemic Brain Injury" 
  Columbia University Medical Center, New York, NY - 1/13/2012
• Pediatric Neurology Grand Rounds: "Self-repair After Brain Injury" 
  Columbia University Medical Center, New York, NY - 1/1/2012
• "Endogenous Stem Cells and Their Role in Recovery from Brain Injury" 
  University of Toronto, Toronto, Canada - 1/14/2011
• Neurology Grand Rounds: "Self-repair After Brain Injury" 
  Cornell University Medical Center, New York, NY - 1/7/2011
• "Self-repair After Brain Injury", Visiting Professor 
  Institute of Developmental Biology Marseilles (IBDM), Marseilles, France - 1/1/2011
• "Genetic Modeling of Acquired Brain Disease" 
  Paris, France - 1/27/2010
• Research Plenary: "Self-repair After Brain Injury" 
  Pittsburgh, PA - 1/16/2010
• "Hippocampal Development and Progenitor Response to Injury" 
  Barrow Neurological Institute, Phoenix, AZ - 1/23/2009
• "Stem Cells, Neurogenesis and Acquired Brain Injury" (plenary talk) 
  Santa Barbara, CA - 1/10/2009
• University of Kansas, Pediatric Grand Rounds: "Hypoxic-ischemic brain injuries in children" 
  Wesley Medical Center, Wichita, KS - 1/28/2008
• "Management of Pediatric Traumatic Brain Injury" (University of Kansas, Visiting Professor) 
  Wesley Medical Center, Wichita, KS - 1/28/2008
• "Early Management of the Child with a Severe Brain Injury" (plenary talk) 
  Boston, MA - 1/14/2008
• Trauma Grand Rounds: "Advances in Pediatric Traumatic Brain Injury" 
  Dell Children's Hospital, Austin, TX - 1/6/2008
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Other

• Editor: "Endogenous Stem Cell-Based Brain Remodeling in Mammals; Humana Press, Junier and Kernie, editors; ISBN 978-1-4899-7398-6" 
  Kernie, S.G.
  1/1/2014