StevenWPipeMD

PubMed

• 26 citations
  Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A.
  Johnny Mahlangu, Radoslaw Kaczmarek, Annette von Drygalski, Susan Shapiro, Sheng-Chieh Chou, Margareth C Ozelo, Gili Kenet, Flora Peyvandi, Michael Wang, Bella Madan, ...> ;The New England Journal of Medicine. 2023 Feb 23
• 5 citations
  Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice-Brief Report.
  Soracha E Ward, Thomas Guest, Ciara Byrne, Patricia Lopes, Jamie M O'Sullivan, Dearbhla Doherty, David O'Connell, Sara Gutierrez Llaneza, Alain Chion, Judicael Fazavan...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2023 Apr 1
• 3 citations
  Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor.
  Einas Elsheikh, Michelle Lavin, Lilian Antunes Heck, Niamh Larkin, Brendan Mullaney, Dearbhla Doherty, Megan Kennedy, Catriona Keenan, Thomas Guest, Brian O'Mahony, Ju...> ;Journal of Thrombosis and Haemostasis. 2023 May 1
• 11 citations
  First conditional marketing authorization approval in the European Union for hemophilia "A" gene therapy.
  Thierry VandenDriessche, Steven W Pipe, Glenn F Pierce, Radoslaw Kaczmarek> ;Molecular Therapy. 2022 Nov 2
• Clinical experience of switching patients with severe hemophilia to rVIII-SingleChain or rIX-FP.
  Johannes Oldenburg, Steven W Pipe, Maria Elisa Mancuso, Robert Klamroth, Abel Hassoun, Martin Olivieri, Georg Goldmann, Gili Kenet, Wolfgang Miesbach, Jolana Schmiedl,...> ;Current Medical Research and Opinion. 2023 Feb 1
• 1 citations
  Characteristics of BAY 2599023 in the Current Treatment Landscape of Hemophilia A Gene Therapy.
  Steven W Pipe, Valder R Arruda, Claudia Lange, Stephen Kitchen, Hermann Eichler, Samuel Wadsworth> ;Current Gene Therapy. 2023 Jan 1
• 12 citations
  Achieving access to haemophilia care in low-income and lower-middle-income countries: expanded Humanitarian Aid Program of the World Federation of Hemophilia after 5 y...
  Glenn F Pierce, Megan Adediran, Saliou Diop, Amy L Dunn, Magdy El Ekiaby, Radoslaw Kaczmarek, Barbara A Konkle, Steven W Pipe, Mark W Skinner, Leonard A Valentino, Fio...> ;The Lancet. Haematology. 2022 Sep 1
• 13 citations
  Surgical outcomes in people with hemophilia A taking emicizumab prophylaxis: experience from the HAVEN 1-4 studies.
  Rebecca Kruse-Jarres, Flora Peyvandi, Johannes Oldenburg, Tiffany Chang, Sammy Chebon, Michelle Y Doral, Stacy E Croteau, Thierry Lambert, Christine L Kempton, Steven ...> ;Blood Advances. 2022 Dec 27
• 7 citations
  Defibrotide Therapy for SARS-CoV-2 ARDS.
  David Frame, Gianni B Scappaticci, Thomas M Braun, Mary Maliarik, Thomas H Sisson, Steven W Pipe, Daniel A Lawrence, Paul G Richardson, Michael Holinstat, Robert C Hyz...> ;Chest. 2022 Aug 1
• 5 citations
  Eptacog beta efficacy and safety in the treatment and control of bleeding in paediatric subjects (<12 years) with haemophilia A or B with inhibitors.
  Steven W Pipe, Cédric Hermans, Meera Chitlur, Manuel Carcao, Giancarlo Castaman, Joanna A Davis, Jonathan Ducore, Amy L Dunn, Miguel Escobar, Janna Journeycake, Osman ...> ;Haemophilia. 2022 Jul 1
• 2 citations
  Challenges and opportunities when transitioning fromgene replacement toCRISPR/Cas9 therapies - a spotlight on hemophilia.
  Oscar G Segurado, Ruhong Jiang, Steven W Pipe> ;Expert Opinion on Biological Therapy. 2022 Sep 1
• 7 citations
  Pain and functional disability amongst adults with moderate and severe haemophilia from the Irish personalised approach to the treatment of haemophilia (iPATH) study.
  Megan Kennedy, Brian O' Mahony, Sheila Roche, Mark McGowan, Evelyn Singleton, Kevin Ryan, Niamh M O' Connell, Steven W Pipe, Michelle Lavin, James S O' Donnell, Peter ...> ;European Journal of Haematology. 2022 Jun 1
• 11 citations
  Gene therapy: Practical aspects of implementation.
  Steven W Pipe, K Rajender Reddy, Pratima Chowdary> ;Haemophilia. 2022 May 1
• 86 citations
  Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A.
  Margareth C Ozelo, Johnny Mahlangu, K John Pasi, Adam Giermasz, Andrew D Leavitt, Michael Laffan, Emily Symington, Doris V Quon, Jiaan-Der Wang, Kathelijne Peerlinck, ...> ;The New England Journal of Medicine. 2022 Mar 17
• 20 citations
  Hemophilia A Gene Therapy: Current and Next-Generation Approaches.
  Steven W. Pipe, Gil Gonen-Yaacovi, Oscar G Segurado> ;Expert Opinion on Biological Therapy. 2021 Nov 16
• 6 citations
  Estimating the risk of thrombotic events in people with congenital hemophilia A using US claims data.
  Imi Faghmous, Francis Nissen, Peter J. Kuebler, Carlos Flores, Anisha M. Patel, Steven W. Pipe> ;Journal of Comparative Effectiveness Research. 2021 Oct 22
• 7 citations
  Patient preference for emicizumab versus prior factor therapy in people with haemophilia A: Results from the HAVEN 3 and HAVEN 4 studies.
  Aric Parnes, Johnny Mahlangu, Steven W. Pipe, Ido Paz-Priel, Michaela Lehle, Peter Trask, Víctor Jiménez-Yuste> ;Haemophilia. 2021 Oct 8
• 3 citations
  Phage display broadly identifies inhibitor-reactive regions in von Willebrand factor.
  Andrew Yee, Manhong Dai, Stacy E. Croteau, Jordan A. Shavit, Steven W. Pipe, David R. Siemieniak, Fan Meng, David W. Ginsburg> ;Journal of Thrombosis and Haemostasis. 2021 Jul 13
• 17 citations
  The effect of emicizumab prophylaxis on long-term, self-reported physical health in persons with haemophilia A without factor VIII inhibitors in the HAVEN 3 and HAVEN ...
  Mark W. Skinner, Claude Negrier, Ido Paz-Priel, Sammy Chebon, Víctor Jiménez-Yuste, Michael U. Callaghan, Michaela Lehle, Markus Niggli, Johnny Mahlangu, Amy D. Shapir...> ;Haemophilia. 2021 Jun 25
• 12 citations
  Evolution of haemophilia integrated care in the era of gene therapy: Treatment centre's readiness in United States and EU.
  Wolfgang Miesbach, K. John Pasi, Steven W. Pipe, Cedric Hermans, Brian O'Mahony, Christine Guelcher, Bruno Steiner, Mark W. Skinner> ;Haemophilia. 2021 Apr 23
• 7 citations
  Vaccination against COVID-19: Rationale, modalities and precautions for patients with haemophilia and other inherited bleeding disorders.
  Radoslaw Kaczmarek, Magdy El Ekiaby, Daniel P. Hart, Cedric Hermans, Michael Makris, Declan Noone, Brian O'Mahony, David Page, Flora Peyvandi, Steven W. Pipe, Thomas S...> ;Haemophilia. 2021 Mar 2
• 1 citations
  Diagnosis and management of von Willebrand disease: A community‐wide effort to deliver evidence‐based clinical practice guidelines
  Barbara A. Konkle, Steven W. Pipe> ;Haemophilia. 2021 Feb 9
• 63 citations
  The changing treatment landscape in haemophilia: from standard half-life clotting factor concentrates to gene editing.
  Maria Elisa Mancuso, Johnny Mahlangu, Steven W. Pipe> ;Lancet. 2021 Feb 13
• 13 citations
  Application of a hemophilia mortality framework to the Emicizumab Global Safety Database
  Flora Peyvandi, Johnny Mahlangu, Steven W. Pipe, Charles R. M. Hay, Glenn F. Pierce, Peter J. Kuebler, Rebecca Kruse-Jarres, Midori Shima> ;Journal of Thrombosis and Haemostasis. 2021 Jan 1
• 6 citations
  Establishment of a framework for assessing mortality in persons with congenital hemophilia A and its application to an adverse event reporting database
  Steven W. Pipe, Rebecca Kruse-Jarres, Johnny Mahlangu, Glenn F. Pierce, Flora Peyvandi, Peter J. Kuebler, Christian De Ford, Fabian Sanabria, Richard H. Ko, Tiffany Ch...> ;Journal of Thrombosis and Haemostasis. 2021 Jan 1
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Abstracts/Posters

• One Year Data from a Phase 2b Trial of AMT-061 (AAV5-Padua hFIX variant), an Enhanced Vector for Gene Transfer in Adults with Severe or Moderate-Severe Hemophilia B
  Steven Pipe, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• Moving Beyond Factor: Shifting the Paradigm in Hemophilia Through Gene Therapy 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Fitusiran, an RNAi Therapeutic Targeting Antithrombin to Restore Hemostatic Balance in Patients with Hemophilia a or B with or without Inhibitors: Management of Acute ... 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• First-in-human Gene Therapy Study of AAVhu37 Capsid Vector Technology in Severe Hemophilia A 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019