Sundeep Khosla MD
Diabetes, Lipid Metabolism, Osteoporosis & Bone Metabolism Medicine
Dr. Francis Chucker and Nathan Landow Research Professor; Director, Mayo Clinic Center for Clinical and Translational Science
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200 1st St SwMayo Clin, Div EndocrinologyRochester, MN 55905
Phone+1 507-284-2511
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Summary
- Dr. Sundeep Khosla is an endocrinologist based in Rochester, MN, specializing in diabetes, lipid metabolism, osteoporosis, and bone metabolism medicine. He completed his medical education at Harvard Medical School in 1982, followed by a residency in internal medicine and a fellowship in endocrinology, diabetes, and metabolism at Massachusetts General Hospital. Since 1988, he has been serving as an attending physician at Mayo Clinic Hospital in Rochester. His expertise includes osteoporosis and age-related bone loss, and he has contributed to the field through numerous publications in high-profile journals. Dr. Khosla is involved in clinical trials focusing on frailty and inflammation in older adults. He has been recognized as one of America's Top Doctors and is an elected member of both the American Society for Clinical Investigation and the Association of American Physicians.
Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1986 - 1987- Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 1982 - 1985
Harvard Medical SchoolClass of 1982
Certifications & Licensure
MN State Medical License 1988 - 2026
AZ State Medical License 1992 - 2005
FL State Medical License 1991 - 2000
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Centricity Enterprise (CE), GE Healthcare, 2014-2017
- CMS Meaningful Use Stage 1 Certification Centricity Patient Online, GE Healthcare, 2014-2017
- CMS Meaningful Use Stage 1 Certification Centricity Patient Online, GE Healthcare, 2014-2017
Clinical Trials
- Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women Start of enrollment: 2018 Feb 06
- Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults Start of enrollment: 2018 Nov 15
Publications & Presentations
PubMed
- Impact of Mild Autonomous Cortisol Secretion on Bone Density, Metabolism, and Microstructure: A Cross-sectional Study.Catherine D Zhang, Jasmine Saini, Sumitabh Singh, Malavika Suresh, Karthik Thangamuthu
The Journal of Clinical Endocrinology and Metabolism. 2026-04-16 - Correction: Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX.John A Kanis, Eugene V McCloskey, Helena Johansson, Enwu Liu, Kristina E Åkesson
Osteoporosis International. 2026-04-01 - Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes.Madison L Doolittle, Mitchell N Froemming, Jennifer L Rowsey, Ming Ruan, Leena Sapra
The Journal of Clinical Investigation. 2026-04-01
Journal Articles
- miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐Related Bone LossSundeep Khosla, MD, Journal of Bone and Mineral Research
- Senolytics Improve Physical Function and Increase Lifespan in Old AgeJames L Kirkland, Nathan K LeBrasseur, S John Weroha, Vesna D Garovic, Sundeep Khosla, Allyson K Palmer, Nature
Press Mentions
How Much Vitamin D Do I Need? The Debate Behind Supplement GuidelinesAugust 5th, 2025- Zombie Cell Killers: New Hope for Aging BonesNovember 1st, 2024
- Is Killing 'Zombie' Cells the Key to Healthier Aging?July 3rd, 2024
Grant Support
- Characterization of senescent cell populations in skeletal agingMAYO CLINIC ROCHESTER2024–2029
- Targeting Cellular Senescence to Extend HealthspanMAYO CLINIC ROCHESTER2019–2029
- Defining the interactions of senescent immune cells and skeletal cellsMAYO CLINIC ROCHESTER2022–2027
- Administrative Supplement to U54 AG079754: Midwest Murine-Tissue Mapping Center (MM-TMC)UNIVERSITY OF MINNESOTA2022–2026
- Administrative Supplement to U54 AG079754: Midwest Murine-Tissue Mapping Center (MM-TMC)UNIVERSITY OF MINNESOTA2022–2026
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