SusanGailKreissmanMD

Pediatric Hematology & Oncology • Durham, NC

Clinical Professor of Pediatrics, Duke University

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Office
330 Trent Dr
# 102382
Durham, NC 27710
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Education & Training

Children's Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 1988 - 1991
Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1985 - 1988
Icahn School of Medicine at Mount SinaiClass of 1985

Certifications & Licensure

NC State Medical License 2000 - 2025
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013

Clinical Trials

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma Start of enrollment: 1996 May 01
Completed
Phase 1
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma Start of enrollment: 2001 Feb 01
Completed
Phase 3
Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
Recruiting
Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma Start of enrollment: 2008 Feb 04
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma Start of enrollment: 2009 Dec 01
Completed
Phase 1
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma Start of enrollment: 2010 Mar 01
Completed
Phase 1
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin Start of enrollment: 2010 Oct 04
Active, not recruiting
Phase 1
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant Start of enrollment: 2013 Mar 21
Completed
Phase 3
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Active, not recruiting
Phase 2
N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan Start of enrollment: 2014 Jan 16
Active, not recruiting
Phase 1
Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma Start of enrollment: 2014 Aug 01
Completed
Phase 2
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Start of enrollment: 2014 Jul 11
Active, not recruiting
Phase 2, Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
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Publications & Presentations

PubMed

1 citations
Impact of Genomic and Clinical Factors on Outcome of Children ≥18 Months of Age with Stage 3 Neuroblastoma with Unfavorable Histology and without MYCN Amplification: A...
Navin Pinto, Arlene Naranjo, Xiangming Ding, Fan F Zhang, Emily Hibbitts, Rebekah Kennedy, Rachelle Tibbetts, Shannon Wong-Michalak, David W Craig, Zarko Manojlovic, M...> ;Clinical Cancer Research. 2023 Apr 14
1 citations
Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: ...
Jason R Fangusaro, Arzu Onar-Thomas, Tina Young Poussaint, Shengjie Wu, Azra H Ligon, Neal Ian Lindeman, Anuradha Banerjee, Roger Packer, Lindsay B Kilburn, Ian F Poll...> ;Neuro-Oncology. 2022 Aug 1
2 citations
Leveraging Clinical Informatics Tools to Extract Cumulative Anthracycline Exposure, Measure Cardiovascular Outcomes, and Assess Guideline Adherence for Children With C...
David H Noyd, Amy M. Berkman, Claire Howell, Steve Power, Susan G Kreissman, Andrew P. Landstrom, Michel G. Khouri, Kevin C. Oeffinger, Warren A. Kibbe> ;JCO Clinical Cancer Informatics. 2021 Oct 29
4 citations
Integration of cancer registry and electronic health record data to construct a childhood cancer survivorship cohort, facilitate risk stratification for late effects, ...
David H Noyd, Nigel B. Neely, Kristin Schroeder, Paul M. Lantos, Steve Power, Susan G. Kreissman, Kevin C. Oeffinger> ;Pediatric Blood & Cancer. 2021 Mar 19
1 citations
More Than Meets the Eye? A Cautionary Tale of Malignant Ectomesenchymoma Treated as Low-risk Orbital Rhabdomyosarcoma.
Tooba Rashid, Rochelle Bagatell, Bruce R. Pawel, Rex C. Bentley, Susan G. Kreissman, Michael D. Deel> ;Journal of Pediatric Hematology/oncology. 2021 Aug 1
26 citations
Prospective Evaluation of Radiation Dose Escalation in Patients With High-Risk Neuroblastoma and Gross Residual Disease After Surgery: A Report From the Children's Onc...
Kevin X. Liu, Arlene Naranjo, Fan F Zhang, Steven G. DuBois, Steve Braunstein, Stephan D. Voss, Geetika Khanna, Wendy B. London, John J. Doski, James D. Geiger, Susan ...> ;Journal of Clinical Oncology. 2020 Jun 12
177 citations
Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial.
Julie R. Park, Susan G. Kreissman, Wendy B. London, Arlene Naranjo, Susan L. Cohn, Michael D. Hogarty, Sheena C. Tenney, Daphne A. Haas-Kogan, Peter J. Shaw, Jacquelin...> ;JAMA. 2019 Aug 27
244 citations
Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, pha...
Jason Fangusaro, Arzu Onar-Thomas, Tina Young Poussaint, Shengjie Wu, Azra H. Ligon, Neal I. Lindeman, Anuradha Banerjee, Roger J. Packer, Lindsay Kilburn, Stewart Gol...> ;The Lancet. Oncology. 2019 May 28
8 citations
Role of the extent of prophylactic regional lymph node radiotherapy on survival in high-risk neuroblastoma: A report from the COG A3973 study.
Steve Braunstein, Wendy B. London, Susan G. Kreissman, Judith G. Villablanca, Andrew M. Davidoff, Kenneth B. DeSantes, Robert P. Castleberry, Kevin Murray, Lisa Diller...> ;Pediatric Blood & Cancer. 2019 Jul 1
41 citations
Predictors of differential response to induction therapy in high-risk neuroblastoma: A report from the Children's Oncology Group (COG).
Navin Pinto, Arlene Naranjo, Emily Hibbitts, Susan G. Kreissman, M. Meaghan Granger, Meredith S. Irwin, Rochelle Bagatell, Wendy B. London, Emily Greengard, Julie R. P...> ;European Journal of Cancer. 2019 May 1
21 citations
Improved contemporary outcomes of liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma
Brian Ezekian, Michael S. Mulvihill, Paul M. Schroder, Brian F. Gilmore, Harold J. Leraas, Brian C. Gulack, Sarah Jane Commander, Alisha Mavis, Susan G. Kreissman, Stu...> ;Pediatric Transplantation. 2018 Oct 19
58 citations
Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.
Pauline Depuydt, Valentina Boeva, Toby Dylan Hocking, Robrecht Cannoodt, Inge M. Ambros, Peter F. Ambros, Shahab Asgharzadeh, Edward F. Attiyeh, Valérie Combaret, Raff...> ;Journal of the National Cancer Institute. 2018 Oct 1
21 citations
MIBG avidity correlates with clinical features, tumor biology, and outcomes in neuroblastoma: A report from the Children’s Oncology Group
Steven G. DuBois, Rajen Mody, Arlene Naranjo, Collin Van Ryn, Douglas Russ, Derek A. Oldridge, Susan G. Kreissman, David L. Baker, Marguerite T. Parisi, Barry L. Shulk...> ;Pediatric Blood & Cancer. 2017 Nov 1
37 citations
Validation of the mIBG skeletal SIOPEN scoring method in two independent high-risk neuroblastoma populations: the SIOPEN/HR-NBL1 and COG-A3973 trials
Ruth Ladenstein, Bieke Lambert, Ulrike Pötschger, Maria Rita Castellani, Val Lewington, Zvi Bar-Sever, Aurore Oudoux, Anna Śliwińska, Katerina Taborska, Lorenzo Biasso...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2018 Feb 1
38 citations
Validation of Postinduction Curie Scores in High-Risk Neuroblastoma: A Children's Oncology Group and SIOPEN Group Report on SIOPEN/HR-NBL1.
Gregory A. Yanik, Marguerite T. Parisi, Arlene Naranjo, Helen Nadel, Michael J. Gelfand, Julie R. Park, Ruth Ladenstein, Ulrike Poetschger, Ariane Boubaker, Dominique ...> ;Journal of Nuclear Medicine. 2018 Mar 1
1 citations
Reply to J. Stenman et al
Michael P. La Quaglia, Daphne A. Haas-Kogan, Julie Park, Susan G. Kreissman, Daniel von Allmen, Andrew M. Davidoff, Wendy B. London, Geetika Khanna> ;Journal of Clinical Oncology. 2017 Apr 19
72 citations
Impact of Extent of Resection on Local Control and Survival in Patients From the COG A3973 Study With High-Risk Neuroblastoma.
Daniel von Allmen, Andrew M. Davidoff, Wendy B. London, Collin Van Ryn, Daphne A. Haas-Kogan, Susan G. Kreissman, Geetika Khanna, Nancy Rosen, Julie R. Park, Michael P...> ;Journal of Clinical Oncology. 2017 Jan 10
4 citations
Erratum to Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Ch...
William Temple, Lori Mendelsohn, Grace E. Kim, Erin A. Nekritz, W. Clay Gustafson, Lawrence Lin, Kathy Giacomini, Arlene Naranjo, Collin Van Ryn, Marguerite T. Parisi,...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2016 Jul 1
10 citations
Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's On...
William Temple, Lori Mendelsohn, Grace E Kim, Erin Nekritz, W Clay Gustafson, Lawrence Lin, Kathy Giacomini, Arlene Naranjo, Collin Van Ryn, Gregory A Yanik, Susan G K...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2016 Mar 1
29 citations
Use of patient registries and administrative datasets for the study of pediatric cancer.
Henry E. Rice, Brian R. Englum, Brian C. Gulack, Obinna O. Adibe, Elizabeth T. Tracy, Susan G. Kreissman, Jonathan C. Routh> ;Pediatric Blood & Cancer. 2015 Sep 1
36 citations
Value of surgical resection in children with high-risk neuroblastoma.
Brian R. Englum, Kristy L. Rialon, Paul J. Speicher, Brian C. Gulack, Timothy A. Driscoll, Susan G. Kreissman, Henry E. Rice> ;Pediatric Blood & Cancer. 2015 Sep 1
12 citations
MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates wi...
Gitta Bleeker, Berthe L. F. van Eck-Smit, Koos H. Zwinderman, Rogier Versteeg, Max M. van Noesel, Boen L. Kam, Gertjan J.L. Kaspers, Annelies van Schie, Susan G. Kreis...> ;European Journal of Nuclear Medicine and Molecular Imaging. 2015 Feb 1
66 citations
Ototoxicity in Children With High-Risk Neuroblastoma: Prevalence, Risk Factors, and Concordance of Grading Scales—A Report From the Children's Oncology Group
Wendy Landier, Kristin Knight, F. Lennie Wong, J. C. K. Lee, Ola Thomas, Heeyoung Kim, Susan G. Kreissman, Mary Lou Schmidt, Lu Chen, Wendy B. London, James G. Gurney> ;Journal of Clinical Oncology. 2014 Feb 20
195 citations
Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial
Susan G. Kreissman, Robert C. Seeger, Katherine K. Matthay, Wendy B. London, Richard Sposto, Stephan A. Grupp, Daphne A. Haas-Kogan, Michael P. LaQuaglia, Alice L. Yu,...> ;The Lancet. Oncology. 2013 Sep 1
128 citations
Semiquantitative mIBG Scoring as a Prognostic Indicator in Patients with Stage 4 Neuroblastoma: A Report from the Children’s Oncology Group
Gregory A. Yanik, Marguerite T. Parisi, Barry L. Shulkin, Arlene Naranjo, Susan G. Kreissman, Wendy B. London, Judith G. Villablanca, John M. Maris, Julie R. Park, Sus...> ;Journal of Nuclear Medicine. 2013 Apr 1
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Journal Articles

Improved Contemporary Outcomes of Liver Transplantation for Pediatric Hepatoblastoma and Hepatocellular Carcinoma
Brian Ezekian, Brian F Gilmore, Harold J Leraas, Stuart J Knechtle, Andrew S Barbas, Brian C Gulack, Alisha M Mavis, Susan G Kreissman, Michael S Mulvihill, Paul M Sch..., Pediatric Transplantation