Thomas E Scammell MD

PubMed

• Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial.
  Gert Jan Lammers, Giuseppe Plazzi, Emmanuel Mignot, Fabio Pizza, Yves Dauvilliers
  JAMA Neurology. 2026-02-01
• 10 citations
  An orexin agonist promotes wakefulness and inhibits cataplexy through distinct brain regions.
  Takashi Ishikawa, Emi Kurimoto, Adam A Joyal, Tatsuki Koike, Haruhide Kimura
  Current Biology. 2025-05-05
• 1 citations
  Impaired sleep-dependent memory consolidation in pediatric narcolepsy type 1.
  Kiran Maski, Gillian Heckler, Jennifer Worhach, Dimitrios Mylonas, Grace Wang
  Sleep. 2025-02-10

Journal Articles

• Damage to histaminergic tuberomammillary neurons and other hypothalamic nuclei with traumatic brain injury  
  Annals of Neurology, 1/1/2015
• Carbachol excites sublaterodorsal nucleus neurons projecting to the spinal cord  
  J Physiol, 1/1/2014
• Optogenetic mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal  
  J Neurosci, 1/1/2014

Books/Book Chapters

• Diagnosis and neurobiology of narcolepsy 
  Chapter: Diagnosis and neurobiology of narcolepsy 
  Editors: Rose B, Sanders M, Benca R, Wilson K.UpToDate: Wolters Kluwer2014
• Diagnosis and neurobiology of narcolepsy 
  Chapter: Treatment of narcolepsy 
  Editors: Sanders M, Benca R, Wilson K.UpToDate: Wolters Kluwer2014
• Narcolepsy: Pathophysiology, Diagnosis, and Treatment 
  Chapter: The neural basis of sleepiness in narcoleptic mice 
  Editors: Baumann, CR, Bassetti, CL, Scammell, TE.Springer, NY2011

Abstracts/Posters

• GABA and glutamatergic projections from the basal forebrain to the MCH neurons
  Sleep, 1/1/2013
• Neural circuitry of cataplexy: projection targets of GABA cells subpopulations in the central amygdala
  Sleep, 1/1/2013
• Basal forebrain efferents to the orexin neurons
  Sleep, 1/1/2013

Lectures

• Interaction of Orexin and Histamine Systems 
  Tallinn, Estonia - 1/1/2014
• Year in Review: Narcolepsy 
  Minneapolis, MN - 1/1/2014
• Neurobiology of Cataplexy 
  Minneapolis, MN - 1/1/2014

Other

• Narcolepsy 
  Harvard Medical School
  1/1/2014
• Commentary on narcolepsy and orexin 
  The Boston Globe
  1/1/2009
• The Sleepy Student 
  Human Nervous System and Behavior course
  1/1/2009