TimothyMMillerMD

PubMed

• Author Correction: A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.
  Katherine E Irwin, Pei Jasin, Kerstin E Braunstein, Irika R Sinha, Mark A Garret, Kyra D Bowden, Koping Chang, Juan C Troncoso, Abhay Moghekar, Esther S Oh, Denitza Ra...> ;Nature Medicine. 2024 Apr 5
• Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau.
  Vemula, P., Schoch, K., Miller, T.> ;Frontiers in Molecular Neuroscience. 2023 Jan 1
• 21 citations
  Antisense Oligonucleotides for the Study and Treatment of ALS.
  Benjamin D Boros, Kathleen M Schoch, Collin J Kreple, Timothy M Miller> ;Neurotherapeutics. 2022 Jul 1
• 33 citations
  Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties.
  Zachary R. Grese, Alliny Cs Bastos, Lohany D Mamede, Rachel L. French, Timothy M. Miller, Yuna M. Ayala> ;EMBO Reports. 2021 Nov 17
• 21 citations
  TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
  Carolina Alquezar, Kathleen M. Schoch, Ethan G. Geier, Eliana Marisa Ramos, Aurora Scrivo, Kathy H. Li, Andrea R. Argouarch, Elisabeth E. Mlynarski, Beth A. Dombroski,...> ;Science Advances. 2021 Nov 5
• 8 citations
  Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial.
  Merit Cudkowicz, Angela Genge, Nicholas J. Maragakis, Susanne Petri, Leonard H. van den Berg, Valtteri V Aho, Toni Sarapohja, Mikko Kuoppamäki, Chris Garratt, Ammar Al...> ;The Lancet. Neurology. 2021 Oct 1
• 37 citations
  Acute Trem2 reduction triggers increased microglial phagocytosis, slowing amyloid deposition in mice.
  Kathleen M. Schoch, Lubov Ezerskiy, Michaela M Morhaus, Riley N Bannon, Andrew D. Sauerbeck, Mark Shabsovich, Paymaan Jafar-Nejad, Frank Rigo, Timothy M. Miller> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jul 6
• 2 citations
  Prescription and acceptance of durable medical equipment in FORTITUDE-ALS, a study of reldesemtiv in ALS: post hoc analyses of a randomized, double-blind, placebo-cont...
  Stacy A. Rudnicki, Jinsy A. Andrews, Angela Genge, Carlayne E. Jackson, Noah Lechtzin, Timothy M. Miller, Bettina M. Cockroft, Fady I. Malik, Lisa Meng, Jenny Wei, And...> ;Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2021 Jul 5
• Is presymptomatic ALS perivascular
  Collin J. Kreple, Kathleen M. Schoch, Timothy M. Miller> ;Nature Medicine. 2021 Apr 1
• 12 citations
  Smartphone data during the COVID-19 pandemic can quantify behavioral changes in people with ALS.
  Anna L. Beukenhorst, Ella Collins, Katherine Burke, Syed Minhajur Rahman, Margaret Clapp, Sai Charan Konanki, Sabrina Paganoni, Timothy M. Miller, James Chan, Jukka-Pe...> ;Muscle & Nerve. 2021 Feb 1
• 87 citations
  Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis
  Sabrina Paganoni, Suzanne Hendrix, Samuel P. Dickson, Newman Knowlton, Eric A. Macklin, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Cares...> ;Muscle & Nerve. 2021 Jan 1
• 44 citations
  Plasma neurofilament light predicts mortality in patients with stroke.
  Tania F. Gendron, Mohammed K. Badi, Michael G. Heckman, Karen Jansen-West, George K. Vilanilam, Patrick W. Johnson, Alexander R. Burch, Ronald L. Walton, Owen A. Ross,...> ;Science Translational Medicine. 2020 Nov 11
• 29 citations
  Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
  Antonietta Franco, Xiawei Dang, Emily K Walton, Joshua N Ho, Barbara Zabłocka, Cindy V. Ly, Timothy M. Miller, Robert H. Baloh, Michael E. Shy, Andrew S. Yoo, Gerald W...> ;Elife. 2020 Oct 19
• 205 citations
  Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis
  Sabrina Paganoni, Eric A. Macklin, Suzanne Hendrix, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Caress, Margaret A. Owegi, Adam Quick, Ja...> ;The New England Journal of Medicine. 2020 Sep 2
• 35 citations
  Amyotrophic lateral sclerosis care and research in the United States during the COVID-19 pandemic: Challenges and opportunities.
  Jinsy A. Andrews, James D. Berry, Robert H. Baloh, Nathan Carberry, Merit Cudkowicz, Brixhilda Dedi, Jonathan D. Glass, Nicholas J. Maragakis, Timothy M. Miller, Sabri...> ;Muscle & Nerve. 2020 Aug 1
• 258 citations
  Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2020 Jul 8
• 13 citations
  A viral toolkit for recording transcription factor–DNA interactions in live mouse tissues
  Alexander J. Cammack, Jiayang Chen, Michael J. Vasek, Mark Shabsovich, Katherine B. McCullough, Allen Yen, Tomas Lagunas, Susan E. Maloney, June He, Xuhua Chen, Misha ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Apr 16
• 19 citations
  CNS microRNA profiles: a database for cell type enriched microRNA expression across the mouse central nervous system.
  Nathan Pomper, Yating Liu, Mariah L. Hoye, Joseph D. Dougherty, Timothy M. Miller> ;Scientific Reports. 2020 Mar 18
• 25 citations
  Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.
  Irit Reichenstein, Chen Eitan, Sandra Diaz-Garcia, Guy Haim, Iddo Magen, Aviad Siany, Mariah L. Hoye, Natali Rivkin, Tsviya Olender, Beáta Tóth, Revital Ravid, Amitai ...> ;Science Translational Medicine. 2019 Dec 18
• 22 citations
  Prospective natural history study of C9orf72 ALS clinical characteristics and biomarkers
  Alexander J. Cammack, Nazem Atassi, Theodore Hyman, Leonard H. van den Berg, Matthew B. Harms, Robert H. Baloh, Robert H. Brown, Michael A. van Es, Jan H. Veldink, Bál...> ;Neurology. 2019 Oct 22
• 1 citations
  Sub-Kelvin cooling for two kilopixel bolometer arrays in the PIPER receiver.
  E R Switzer, P A R Ade, T Baildon, D Benford, C L Bennett, D T Chuss, R Datta, J R Eimer, D J Fixsen, N N Gandilo, T M Essinger-Hileman, M Halpern, G Hilton, K Irwin, ...> ;The Review of Scientific Instruments. 2019 Sep 1
• 34 citations
  SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.
  Ross W. Paterson, Audrey Gabelle, Brendan P. Lucey, Nicolas R. Barthélemy, Claire A Leckey, Christophe Hirtz, Sylvain Lehmann, Chihiro Sato, Bruce W. Patterson, Tim We...> ;Nature Reviews. Neurology. 2019 Jun 20
• 10 citations
  An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis
  Ilya Gertsman, Joanne Wuu, Melissa McAlonis-Downes, Majid Ghassemian, Karen Ling, Frank Rigo, Frank C. Bennett, Michael Benatar, Timothy M. Miller, Sandrine Da Cruz> ;JCI Insight. 2019 May 16
• 3 citations
  Tau positron emission tomography imaging in C9orf72 repeat expansion carriers.
  Cindy V. Ly, Lauren N. Koenig, Jon Christensen, Brian A. Gordon, Helen Beaumont, Sonika Dahiya, Jie Chen, Yi Su, Brittany Nelson, Jennifer Jockel-Balsarotti, Caroline ...> ;European Journal of Neurology. 2019 Mar 25
• 6 citations
  Protein production is an early biomarker for RNA-targeted therapies.
  Wade K. Self, Kathleen M. Schoch, Jacob Alex, Nicolas R. Barthélemy, James G. Bollinger, Chihiro Sato, Tracy Cole, Holly B. Kordasiewicz, Eric E. Swayze, Randall J. Ba...> ;Annals of Clinical and Translational Neurology. 2018 Oct 14
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