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Todd Druley, MD, Pediatric Hematology & Oncology, Saint Louis, MO

ToddEDruleyMDPhD

Pediatric Hematology & Oncology • Saint Louis, MO

Chief Medical Officer; ANGLE Biosciences Inc.

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Summary

  • Todd Druley, MD, PhD is the Chief Medical Officer of ANGLE Biosciences. He received his medical and graduate degrees from University of Illinois before moving to Washington University School of Medicine in St. Louis to study pediatric oncology as a physician-scientist. He is experienced in molecular diagnostics, cancer genetics, genetic variation, and population genetics.

Education & Training

  • Washington University/B-JH/SLCH Consortium
    Washington University/B-JH/SLCH ConsortiumFellowship, Pediatric Hematology/Oncology, 2005 - 2008
  • Washington University School of Medicine
    Washington University School of MedicinePediatric, 2003 - 2005
  • Washington University School of Medicine
    Washington University School of MedicinePediatric, 2002 - 2003
  • University of Illinois College of Medicine
    University of Illinois College of MedicineM.D./Ph.D, Training Program, 1994 - 2002
  • University of Illinois College of Medicine
    University of Illinois College of MedicineClass of 2002, MD, PhD
  • University of Illinois at Chicago
    University of Illinois at ChicagoMD, PhD, Medicine, Molecular Genetics, 2002
  • University of Illinois at Urbana-Champaign
    University of Illinois at Urbana-ChampaignBS, Cell and Structural Biology, 1994

Certifications & Licensure

  • MO State Medical License
    MO State Medical License 2008 - 2025
  • American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

  • Elected Member American Society of Clinical Investigators, 2019
  • Hyundai Quantum Award Hyundai Hope on Wheels, 2018
  • Scholar Award Leukemia & Lymphoma Society, 2018
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Publications & Presentations

PubMed

Journal Articles

  • Mechanistic analysis of the multidrug transporter P-glycoprotein using a conformation-sensitive antibody.  
    Druley TE, Ruth AC, Stein WD and Roninson IB, Proc. Amer. Assn. Cancer Res. 41: 762, 2000
  • Detection of rare genomic variants from pooled sequencing using SPLINTER.  
    Vallania FLM, Ramos E, Cresci S, Mitra RD, Druley TE, J. of Visualized Experiments. 64: e3943, DOI: 10.3791/3943
  • Traditional and targeted exome sequencing reveals common, rare and novel deleterious variants in RET signaling complex in a cohort of living US patients with urinary t...  
    Chatterjee R, Ramos E, Hoffman M, VanWinkle J, Martin D, Davis TK, Hoshi M, Hmiel SP, Beck A, Hruska K, Coplen D, Liapis H, Mitra R, Druley T, Austin P, Jain S, Human Genetics. “PMC Journal – In Process”

Abstracts/Posters

  • High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction
    Todd E Druley, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Generation, Characterization and Pre-Clinical Drug Evaluation of Patient-Derived Xenograft Models of Pediatric Down Syndrome AML
    Todd E Druley, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

  • Investigating the Effects of Clonal Hematopoiesis in Healthy Marrow and Blood Donors on the Outcomes of Recipients Following Hematopoietic Stem Cell Transplantation 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Authored Content

  • Minimal Residual Disease Testing - Current Innovations and Future DirectionsNovember 2018

Press Mentions

  • Single-Cell Resolved Imaging Reveals Intra-Tumor Heterogeneity in Glycolysis, Transitions Between Metabolic States, and Their Regulatory Mechanisms
    Single-Cell Resolved Imaging Reveals Intra-Tumor Heterogeneity in Glycolysis, Transitions Between Metabolic States, and Their Regulatory MechanismsFebruary 16th, 2021
  • Novel Mutations in Stem Cells of Young Donors Can Be Passed to Recipients
    Novel Mutations in Stem Cells of Young Donors Can Be Passed to RecipientsJanuary 20th, 2020
  • Previously Unseen Mutations in Stem Cells of Young Donors Can Be Passed to Recipients, Study Finds
    Previously Unseen Mutations in Stem Cells of Young Donors Can Be Passed to Recipients, Study FindsJanuary 15th, 2020
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Professional Memberships

  • American Society of Hematology - ASH
    Member
  • American Association for Cancer Research - AACR
    Member
  • American Society for Pediatric Hematology and Oncology - ASPHO
    Member
  • American Society of Clinical Investigators - ASCI
    Member

Industry Relationships

  • Chief Medical Officer, ArcherDX, Inc2019 - Present
  • Co-Inventor of RareSeq, Canopy BiosciencesDisclosure: The RareSeq method was developed as error-corrected sequencing (ECS) by the Druley lab. A patent held by Washington Univ is pending and the technology has been licensed by Canopy Biosciences.2018 - Present

Dr. Todd Druley, Dr. Todd Druley, MD, Dr. T Druley, Dr. Todd E Druley