UmaMalhotraMD

Infectious Disease • Seattle, WA

Physician

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Office
Ambulatory Clinic
825 Eastlake Avenue East
Seattle, WA 98109
Phone+1 206-288-1000
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Education & Training

University of WashingtonFellowship, Infectious Disease, 1995 - 1998
California Pacific Medical CenterResidency, Internal Medicine, 1992 - 1994
Oregon Health & Science UniversityInternship, Internal Medicine, 1991 - 1992
All India Institute of Medical SciencesClass of 1985

Certifications & Licensure

CA State Medical License 1992 - Present
WA State Medical License 1995 - 2024
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification HealthSentry EHR, Cerner Corporation, 2013

Publications & Presentations

PubMed

23 citations
Cross-reactive and mono-reactive SARS-CoV-2 CD4+ T cells in prepandemic and COVID-19 convalescent individuals.
Alexandra M Johansson, Uma Malhotra, Yeseul G Kim, Rebecca Gomez, Maxwell P Krist, Anna Wald, David M Koelle, William W Kwok> ;Plos Pathogens. 2021 Dec 1
31 citations
Endomembrane targeting of human OAS1 p46 augments antiviral activity.
Frank Soveg, Johannes Schwerk, Nandan S. Gokhale, Karen Cerosaletti, Julian R. Smith, Erola Pairo-Castineira, Alison M. Kell, Adriana Forero, Shivam A. Zaver, Katharin...> ;Elife. 2021 Aug 3
Early Prognostic Indicators of Subsequent Hospitalization in Patients with Mild COVID-19
Alyssa Ylescupidez, Aaron Rips, Henry T. Bahnson, Cate Speake, Punam Verma, Anne M. Hocking, Jane H. Buckner, Uma Malhotra> ;Journal of Clinical Medicine. 2021 Apr 8
22 citations
The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
Hamid Bolouri, Cate Speake, David A. G. Skibinski, S. Alice Long, Anne M. Hocking, Daniel J. Campbell, Jessica A. Hamerman, Uma Malhotra, Jane H. Buckner> ;The Journal of Clinical Investigation. 2021 Feb 1
6 citations
Ontogeny of different subsets of yellow fever virus-specific circulatory CXCR5 + CD4 + T cells after yellow fever vaccination
Quinn DeGottardi, Theresa J. Gates, Junbao Yang, Eddie A. James, Uma Malhotra, I-Ting Chow, Yannick Simoni, Michael Fehlings, Evan W. Newell, Hannah A. DeBerg, William...> ;Scientific Reports. 2020 Sep 24
8 citations
Acute Limb Ischemia as Sole Initial Manifestation of SARS-CoV-2 Infection.
Owen Thompson, Damon Pierce, Dennis Whang, Meaghan O'Malley, Bob Geise, Uma Malhotra> ;Journal of Vascular Surgery Cases and Innovative Techniques. 2020 Aug 21
22 citations
Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome.
Eddie A. James, Theresa J. Gates, Rebecca E. LaFond, Shinobu Yamamoto, Chester Ni, Duy T. Mai, Vivian H. Gersuk, Kimberly O’Brien, Quynh-Anh Nguyen, Brad Zeitner, Mari...> ;Plos Pathogens. 2016 Jan 21
1 citations
Cyclophosphamide Treatment for Acquired Factor VIII Inhibitor in a Patient with AIDS-Associated Progressive Multifocal Leukoencephalopathy.
Uma Malhotra, David M. Aboulafia> ;Journal of the International Association of Providers of AIDS Care. 2016 Mar 1
61 citations
Yellow Fever Vaccination Elicits Broad Functional CD4+ T Cell Responses That Recognize Structural and Nonstructural Proteins
Eddie A. James, Rebecca E. LaFond, Theresa J. Gates, Duy T. Mai, Uma Malhotra, William W. Kwok> ;Journal of Virology. 2013 Dec 1
36 citations
CD4+ T cells recognize unique and conserved 2009 H1N1 influenza hemagglutinin epitopes after natural infection and vaccination
Junbao Yang, Eddie A. James, Theresa J. Gates, Jonathan H. DeLong, Rebecca E. LaFond, Uma Malhotra, William W. Kwok> ;International Immunology. 2013 Mar 22
Widespread availability of artemisinin monotherapy in the United States.
Robert M. Rakita, Uma Malhotra> ;Emerging Infectious Diseases. 2011 May 1
6 citations
Functional properties and epitope characteristics of T-cells recognizing natural HIV-1 variants.
Uma Malhotra, Jessica Nolin, Helen Horton, Fusheng Li, Lawrence Corey, Ji I. Mullins, Mj J. McElrath> ;Vaccine. 2009 Nov 12
5 citations
Characterization of Gag and Nef-specific ELISpot-based CTL responses in HIV-1 infected Indian individuals.
Sanjay Mendiratta, Madhu Vajpayee, Uma Malhotra, Shweta Kaushik, Lalit Dar, Kamalika Mojumdar, Neeraj Chauhan, Vishnubhatla Sreenivas> ;Medical Microbiology and Immunology. 2009 Feb 1
30 citations
Generation of HIV-1-specific CD8+ cell responses following allogeneic hematopoietic cell transplantation.
Ann E. Woolfrey, Uma Malhotra, Robert D. Harrington, John McNevin, Thomas J. Manley, Stanley R. Riddell, Robert W. Coombs, Frederick R. Appelbaum, Lawrence Corey, Rain...> ;Blood. 2008 Oct 15
7 citations
Towards prediction of degenerate CTL epitope recognition.
Fusheng Li, Denise M. McKenney, Uma Malhotra, Claire Crimi, Jessica Nolin, Lawrence Corey, Juliana M. McElrath, Mark Newman, Steven G. Self> ;Human Vaccines. 2008 Mar 1
42 citations
Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.
Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, M. Juliana McElrath> ;Journal of Virology. 2007 May 15
24 citations
Comprehensive epitope analysis of cross-clade Gag-specific T-cell responses in individuals with early HIV-1 infection in the US epidemic
Uma Malhotra, Jessica Nolin, James I. Mullins, M. Juliana McElrath> ;Vaccine. 2007 Jan 4
93 citations
Peptide selection for human immunodeficiency virus type 1 CTL-based vaccine evaluation.
Fusheng Li, Uma Malhotra, Peter B. Gilbert, Natalie Hawkins, Ann Duerr, Juliana M. McElrath, Lawrence Corey, Steven G. Self> ;Vaccine. 2006 Nov 17
26 citations
Abacavir hypersensitivity reaction in primary HIV infection.
Joanne Stekler, Janine Maenza, Claire E. Stevens, Sarah Holte, Uma Malhotra, M. Juliana McElrath, Lawrence Corey, Ann C. Collier> ;AIDS. 2006 Jun 12
11 citations
CD4+ T cell receptor repertoire perturbations in HIV-1 infection: association with plasma viremia and disease progression.
Uma Malhotra, Claire Huntsberry, Sarah Holte, Jean Lee, Lawrence Corey, M. Juliana McElrath> ;Clinical Immunology. 2006 Apr 1
5 citations
Effect of adjunct hydroxyurea on helper T cell immunity in HIV type 1-infected patients with virological suppression
Uma Malhotra, Ronald J. Bosch, Rui Wang, Ann C. Collier, M. Juliana McElrath> ;AIDS Research and Human Retroviruses. 2004 Aug 25
7 citations
HIV-1-Infected Patients with Envelope-Specific Lymphoproliferation or Long-Term Nonprogression Lack Antibodies Suppressing Glycoprotein 120 Antigen Presentation
Peter Chien, Daniel Chen, Pei-de Chen, Michael Tuen, Stephen A. Migueles, Mark Connors, Eric S. Rosenberg, Uma Malhotra, Charles J. Gonzalez, Catarina E. Hioe> ;The Journal of Infectious Diseases. 2004 Mar 1
6 citations
Association of T cell proliferative responses and phenotype with virus control in chronic progressive HIV-1 disease.
Uma Malhotra, Ronald J. Bosch, Ellen Chan, Rui Wang, Margaret A. Fischl, Ann C. Collier, M. Juliana McElrath> ;The Journal of Infectious Diseases. 2004 Feb 1
104 citations
Evolution of CD8+ T cell immunity and viral escape following acute HIV-1 infection.
Jianhong Cao, John McNevin, Uma Malhotra, M. Juliana McElrath> ;Journal of Immunology. 2003 Oct 1
32 citations
Early Induction and Maintenance of Env-Specific T-Helper Cells following Human Immunodeficiency Virus Type 1 Infection
Uma Malhotra, Sarah Holte, Tuofu Zhu, Elizabeth Delpit, Claire Huntsberry, Alessandro Sette, Raj Shankarappa, Janine Maenza, Lawrence Corey, M. Juliana McElrath> ;Journal of Virology. 2003 Feb 15
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Press Mentions

Protecting Yourself and Others During the Current Flu EpidemicJanuary 11th, 2017

Grant Support

HIV-1 Diversity In Vaccine Evaluation And DesignNational Institute Of Allergy And Infectious Diseases2005–2006
T-Helper Function In Acute Hiv--Modulation With TherapyNational Institute Of Allergy And Infectious Diseases1998–2002