UnaO'DohertyMD

Pathology • Philadelphia, PA

Anatomic Pathology, Clinical Pathology

Associate Professor, Pathology & Laboratory Medicine, Perelman School of Medicine

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Office
3400 Spruce St
Ste 3WHITE
Philadelphia, PA 19104
Phone+1 215-662-3446
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Summary

Dr. Una O'Doherty is a pathologist in Philadelphia, PA and is affiliated with multiple hospitals in the area, including Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, and Pennsylvania Hospital. She received her medical degree from Weill Cornell Medicine and has been in practice 22 years. She specializes in anatomic pathology and clinical pathology.

Education & Training

University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 1996 - 2001
NYU Grossman School of MedicineResidency, Pathology-Anatomic and Clinical, 1995 - 1999
Weill Cornell MedicineClass of 1995

Certifications & Licensure

GA State Medical License 2024 - 2025
PA State Medical License 1997 - 2024
American Board of Pathology Clinical Pathology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012

Publications & Presentations

PubMed

8 citations
Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking.
Hui Chen, Zhao Li, Sheng Feng, Melissa Richard-Greenblatt, Emily Hutson, Stefen Andrianus, Laurel J Glaser, Kyle G. Rodino, Jianing Qian, Dinesh Jayaraman, Ronald G Co...> ;Clinical Chemistry. 2021 Aug 12
16 citations
Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication.
Marilia Rita Pinzone, Sam Weissman, Alexander O. Pasternak, Ryan Zurakowski, Stephen A. Migueles, Una O'Doherty> ;JCI Insight. 2021 Aug 23
3 citations
Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking
Hui Chen, Zhao Li, Sheng Feng, Anni Wang, Melissa Richard-Greenblatt, Emily Hutson, Stefen Andrianus, Laurel Glaser, Kyle G. Rodino, Jianing Qian, Dinesh Jayaraman, Ro...> ;Medrxiv. 2021 Mar 26
32 citations
Persistence of an intact HIV reservoir in phenotypically naive T cells
Emmanuele Venanzi Rullo, Marilia Rita Pinzone, LaMont Cannon, Sam Weissman, Manuela Ceccarelli, Ryan Zurakowski, Giuseppe Nunnari, Una O'Doherty> ;JCI Insight. 2020 Oct 15
8 citations
Interferon-α alters host glycosylation machinery during treated HIV infection
Leila B. Giron, Florent Colomb, Emmanouil Papasavvas, Livio Azzoni, Xiangfan Yin, Matthew Fair, Alitzel Anzurez, Mohammad Damra, Karam Mounzer, Jay R. Kostman, Pablo T...> ;Ebiomedicine. 2020 Sep 1
6 citations
Next-Generation Sequencing in a Direct Model of HIV Infection Reveals Important Parallels to and Differences from In Vivo Reservoir Dynamics.
Marilia Rita Pinzone, Maria Paola Bertuccio, D. Jake VanBelzen, Ryan Zurakowski, Una O'Doherty> ;Journal of Virology. 2020 Apr 16
26 citations
Genetic Evidence That Naive T Cells Can Contribute Significantly to the Human Immunodeficiency Virus Intact Reservoir: Time to Re-evaluate Their Role.
Emmanuele Venanzi Rullo, LaMont Cannon, Marilia Rita Pinzone, Manuela Ceccarelli, Giuseppe Nunnari, Una O'Doherty> ;Clinical Infectious Diseases. 2019 Nov 27
3 citations
Heavy metal protease takes a tiki torch to HIV assembly
Una O'Doherty, Eric O Freed> ;Nature Immunology. 2019 Jun 1
127 citations
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion.
Marilia Rita Pinzone, D. Jake VanBelzen, Sam Weissman, Maria Paola Bertuccio, LaMont Cannon, Emmanuele Venanzi-Rullo, Stephen A. Migueles, R. Brad Jones, Talia M. Mota...> ;Nature Communications. 2019 Feb 13
1 citations
More efficient exchange of sickle red blood cells can be achieved by exchanging the densest red blood cells: An ex vivo proof of concept study.
Suzanne R. Thibodeaux, Yvette C. Tanhehco, Leah Irwin, Lita Jamensky, Kevin Schell, Una O'Doherty> ;Transfusion and Apheresis Science. 2019 Feb 1
14 citations
Quantitation of Integrated HIV Provirus by Pulsed-Field Gel Electrophoresis and Droplet Digital PCR.
Steven M. Lada, Karissa Huang, D. Jake VanBelzen, Luis J. Montaner, Una O'Doherty, Douglas D. Richman> ;Journal of Clinical Microbiology. 2018 Nov 27
19 citations
HLA-C downregulation by HIV-1 adapts to host HLA genotype.
Nathaniel D. Bachtel, Gisele Umviligihozo, Suzanne Pickering, Talia M. Mota, Hua Liang, Gregory Q. Del Prete, Pramita Chatterjee, Guinevere Q. Lee, Rasmi Thomas, Mark ...> ;Plos Pathogens. 2018 Sep 4
16 citations
HIV Protease-Generated Casp8p41, When Bound and Inactivated by Bcl2, Is Degraded by the Proteasome.
Sekar Natesampillai, Nathan W. Cummins, Zilin Nie, Rahul Sampath, Jason V. Baker, Keith Henry, Marilia Rita Pinzone, Una O'Doherty, Eric C. Polley, Gary D. Bren, David...> ;Journal of Virology. 2018 Jul 1
23 citations
Effect of Short-Term Antiretroviral Therapy Interruption on Levels of Integrated HIV DNA.
Zachary Strongin, Radwa Sharaf, D. Jake VanBelzen, Jeffrey M. Jacobson, Elizabeth Connick, Paul A. Volberding, Daniel J. Skiest, Rajesh T. Gandhi, Daniel R. Kuritzkes,...> ;Journal of Virology. 2018 May 29
430 citations
Clinical use of lentiviral vectors.
Michael C. Milone, Una O'Doherty> ;Leukemia. 2018 Mar 22
19 citations
Measuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintained
Marilia Rita Pinzone, Una O'Doherty> ;Retrovirology. 2018 Feb 17
67 citations
Beyond the replication-competent HIV reservoir: transcription and translation-competent reservoirs.
Amy E. Baxter, Una O'Doherty, Daniel E. Kaufmann> ;Retrovirology. 2018 Feb 2
Rapid prediction of stem cell mobilization using volume and conductivity data from automated hematology analyzers.
Carlos H. Villa, Thomas Porturas, Mary Sell, Mark Wall, Gene DeLeo, Jenna Fetters, Sam Mignono, Leah Irwin, Wei-Ting Hwang, Una O'Doherty> ;Transfusion. 2018 Feb 1
25 citations
Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.
Gonzalo Tapia, Jesper F Højen, Mats Ökvist, Rikke Olesen, Steffen Leth, Sara K. Nissen, D.J. VanBelzen, Una O'Doherty, A. Mørk, Kim Krogsgaard, Ole S. Søgaard, Lars Øs...> ;The Journal of Infection. 2017 Dec 1
17 citations
Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size.
Marilia Rita Pinzone, Erin H. Graf, Lindsay Lynch, Brigit McLaughlin, Frederick Hecht, Mark Connors, Stephen A. Migueles, Wei-Ting Hwang, Giuseppe Nunnari, Una O'Doherty> ;Journal of Virology. 2016 Dec 1
6 citations
Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
Maud Mavigner, S. Thera Lee, Jakob Habib, Cameron Robinson, Guido Silvestri, Una O'Doherty, Ann Chahroudi> ;Journal of Virus Eradication. 2016 Oct 5
25 citations
Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.
Sulggi A. Lee, Peter Bacchetti, Nicolas Chomont, Rémi Fromentin, Sharon R Lewin, Una O'Doherty, Sarah Palmer, Douglas D. Richman, Janet D. Siliciano, Steven A. Yukl, S...> ;Plos One. 2016 Aug 2
247 citations
Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy.
Hiromi Imamichi, Robin L. Dewar, Joseph W. Adelsberger, Catherine Rehm, Una O'Doherty, Ellen E. Paxinos, Anthony S. Fauci, H. Clifford Lane> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Aug 2
22 citations
Minor Contribution of Chimeric Host-HIV Readthrough Transcripts to the Level of HIV Cell-Associated gag RNA.
Alexander O. Pasternak, Laura K. DeMaster, Neeltje A. Kootstra, Peter Reiss, Una O'Doherty, Ben Berkhout> ;Journal of Virology. 2016 Jan 15
48 citations
A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy
Laura K. DeMaster, Xiaohe Liu, D. Jake VanBelzen, Benjamin Trinité, Lingjie Zheng, Luis M. Agosto, Stephen A. Migueles, Mark Connors, Lidia Sambucetti, David N. Levy, ...> ;Journal of Virology. 2016 Mar 1
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Hospital Affiliations

Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania
Penn Presbyterian Medical CenterPhiladelphia, Pennsylvania
Pennsylvania HospitalPhiladelphia, Pennsylvania