WarrenSPearMDPhD
Pathology • Philadelphia, PAMolecular Genetics, Anatomic Pathology, Clinical Pathology
Professor, Pathology & Laboratory Medicine, Perelman School of Medicine
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Office
3400 Spruce St
Philadelphia, PA 19104Phone+1 215-662-6503- Is this information wrong?
Education & Training
MIT & Rockefeller UniversityPost-Doctoral Fellowship, Cancer Biology (David Baltimore), 1991 - 1996
Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1989 - 1991
University of Rochester School of Medicine and DentistryClass of 1989, MD- Karolinska InstitutePhD, Tumor Biology, 1983 - 1987
- Williams CollegeBA, Economics, 1976 - 1980
Certifications & Licensure
PA State Medical License 1996 - 2024- American Board of Pathology Clinical Pathology
Awards, Honors, & Recognition
- Elected Member Association of American Physicians (AAP), 2002
- Elected Member American Society of Clinical Investigation (ASCI)
Publications & Presentations
PubMed
- The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLRCD8effector state, and its deletion improves checkpoint blockade.Susan E McClory, Oishi Bardhan, Kelly S Rome, Josephine R Giles, Amy E Baxter, Lanwei Xu, Phyllis A Gimotty, Robert B Faryabi, E John Wherry, Warren S Pear, Martha S J...> ;Cell Reports. 2023 Aug 29
- The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLRCD8effector state and its deletion improves checkpoint blockade.Susan E McClory, Oishi Bardhan, Kelly S Rome, Josephine R Giles, Amy E Baxter, Lanwei Xu, Phyllis A Gimotty, Robert B Faryabi, E John Wherry, Warren S Pear, Martha S J...> ;Biorxiv. 2023 Feb 16
- 1 citationsc-Rel-dependent monocytes are potent immune suppressor cells in cancer.Ting Li, Mayassa J Bou-Dargham, Norman Fultang, Xinyuan Li, Warren S Pear, Honghong Sun, Youhai H Chen> ;Journal of Leukocyte Biology. 2022 Oct 1
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Journal Articles
- Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative NeoplasmErik A Ranheim, David Yang, Warren S Pear, Lan Zhou, Mignon Loh, Eric Padron, Elliot Stieglitz, Nature
Press Mentions
Systemic Notch Downregulation Promotes KrasG12D‐Induced Myeloproliferative NeoplasmMarch 31st, 2019
Linking Mutations in Notch Gene to Role in B-cell CancersNovember 25th, 2017
Newly Described Type of Immune Cell and T Cells Share Similar Path to MaturityMay 14th, 2013
Grant Support
- Immunobiology Of Normal And Neoplastic LymphocytesNational Cancer Institute2010–2012
- The Function Of Tribbles In The Pathogenesis Of AMLNational Cancer Institute2007–2011
- Retroviral Transduction CoreNational Cancer Institute2007–2011
- Oncogenic Notch Signaling: Mouse ModelingNational Cancer Institute2006–2010
- Notch Regulation Of Hematopoetic Cell FatesNational Institute Of Allergy And Infectious Diseases2000–2010
- Pathogenesis Of Chronic Myelogenous LeukemiaNational Cancer Institute1999–2003
- Signals Downstream Of Notch Regulating Lymphoid Cell Fate And FunctionNational Cancer Institute2002
- Notch Signaling In B Cell Development And SurvivalNational Cancer Institute2002
- Core--Retroviral Transduction Of Murine Bone Marrow For In Vivo AnalysisNational Cancer Institute2002
Hospital Affiliations
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania- Penn Presbyterian Medical CenterPhiladelphia, Pennsylvania
Pennsylvania HospitalPhiladelphia, Pennsylvania
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