WilliamYKimMD

PubMed

• Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy
  Sara E Wobker, William Y Kim> ;Clinical Cancer Research.
• Immuno-PET imaging of tumor-infiltrating lymphocytes using zirconium-89 radiolabeled anti-CD3 antibody in immune-competent mice bearing syngeneic tumors.
  Beckford Vera, D. R.,Smith, C. C.,Bixby, L. M.,Glatt, D. M.,Dunn, S. S.,Saito, R.,Kim, W. Y.,Serody, J. S.,Vincent, B. G.,Parrott, M. C.> ;PLoS ONE. 2018 Mar 08
• Consequences of VHL Loss on Global DNA Methylome.
  Robinson, C. M.,Lefebvre, F.,Poon, B. P.,Bousard, A.,Fan, X.,Lathrop, M.,Tost, J.,Kim, W. Y.,Riazalhosseini, Y.,Ohh, M.> ;Sci Rep. 2018 Feb 22
• Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin.
  Miao, L.,Wang, Y.,Lin, C. M.,Xiong, Y.,Chen, N.,Zhang, L.,Kim, W. Y.,Huang, L.> ;J Control Release. 2015 Aug 19
• Genetic Evidence of a Precisely Tuned Dysregulation in the Hypoxia Signaling Pathway during Oncogenesis.
  Couvé, S.,Ladroue, C.,Laine, E.,Mahtouk, K.,Guégan, J.,Gad, S.,Le Jeune, H.,Le Gentil, M.,Nuel, G.,Kim, W. Y.,Lecomte, B.,Pagès, J. C.,Collin, C.,Lasne, F.,Benusiglio,...> ;Cancer Res.. 2014 Nov 06
• Trends in stage-specific incidence rates for urothelial carcinoma of the bladder in the United States: 1988 to 2006.
  Nielsen, M. E.,Smith, A. B.,Meyer, A. M.,Kuo, T. M.,Tyree, S.,Kim, W. Y.,Milowsky, M. I.,Pruthi, R. S.,Millikan, R. C.> ;Cancer. 2013 Oct 15
• Stearoyl Co-A Desaturase 1 as a ccRCC Therapeutic Target: Death by Stress.
  Leung, J. Y.,Kim, W. Y.> ;Clin. Cancer Res.. 2013 Jun 15
• Roadmap for the development of the University of North Carolina at Chapel Hill Genitourinary OncoLogy Database-UNC GOLD.
  Gallagher, S. A.,Smith, A. B.,Matthews, J. E.,Potter, C. W.,Woods, M. E.,Raynor, M.,Wallen, E. M.,Kimryn Rathmell, W.,Whang, Y. E.,Kim, W. Y.,Godley, P. A.,Chen, R. C....> ;Urol. Oncol.. 2013 Feb 19
• A phase II study of lapatinib, a dual EGFR and HER-2 tyrosine kinase inhibitor, in patients with castration-resistant prostate cancer.
  Whang, Y. E.,Armstrong, A. J.,Rathmell, W. K.,Godley, P. A.,Kim, W. Y.,Pruthi, R. S.,Wallen, E. M.,Crane, J. M.,Moore, D. T.,Grigson, G.,Morris, K.,Watkins, C. P.,Geor...> ;Urol Oncol. 2013 Jan
• 152 citations
  Double-Blind, Randomized Trial of Docetaxel Plus Vandetanib Versus Docetaxel Plus Placebo in Platinum-Pretreated Metastatic Urothelial Cancer
  Toni K. Choueiri, Robert W. Ross, Susanna Jacobus, Ulka N. Vaishampayan, Evan Y. Yu, David I. Quinn, Noah M. Hahn, Thomas E. Hutson, Guru Sonpavde, Stephanie Morrissey...> ;Journal of Clinical Oncology. 2012 Feb 10
• 58 citations
  Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia
  Ryan C. Russell, Roxana I. Sufan, Bing Zhou, Pardeep Heir, Severa Bunda, Stephanie S Sybingco, Samantha N Greer, Olga Roche, Samuel A. Heathcote, Vinca W. K. Chow, Luk...> ;Nature Medicine. 2011 Jul 1
• 85 citations
  A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results
  Raj S. Pruthi, Matthew E. Nielsen, Samuel A. Heathcote, Eric Wallen, W. Kim Rathmell, Paul A. Godley, Young E. Whang, Julia R. Fielding, Heather Schultz, Gayle Grigson...> ;BJU International. 2010 Aug 1
• 194 citations
  Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors
  Julian Carretero, Takeshi Shimamura, Klarisa Rikova, Autumn L. Jackson, Matthew D. Wilkerson, Christa L. Borgman, Matthew S. Buttarazzi, Benjamin A. Sanofsky, Kate McN...> ;Cancer Cell. 2010 Jun 15
• 122 citations
  HIF2α cooperates with RAS to promote lung tumorigenesis in mice
  William Y. Kim, Samanthi A. Perera, Bing Zhou, Julian Carretero, Jen Jen Yeh, Samuel A. Heathcote, Autumn L. Jackson, Petros Nikolinakos, Beatriz Ospina, George N. Nau...> ;The Journal of Clinical Investigation. 2009 Aug 3
• 39 citations
  mTOR pathway in renal cell carcinoma
  Sara C. Hanna, Samuel A. Heathcote, William Y. Kim> ;Expert Review of Anticancer Therapy. 2008 Feb 1
• 90 citations
  CD200 is induced by ERK and is a potential therapeutic target in melanoma
  Kimberly B. Petermann, Gabriela I. Rozenberg, Daniel C. Zedek, Pamela A. Groben, Karen P. McKinnon, Christin Buehler, William Y. Kim, Janiel M. Shields, Shannon N. Pen...> ;The Journal of Clinical Investigation. 2007 Dec 3
• 345 citations
  The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
  Hongbin Ji, Danan Li, Liang Chen, Takeshi Shimamura, Susumu Kobayashi, Kate McNamara, Umar Mahmood, Albert Mitchell, Yangping Sun, Ruqayyah Al-Hashem, Lucian R. Chirie...> ;Cancer Cell. 2006 Jun 13
• 151 citations
  An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells
  Michael Ohh, William Y. Kim, Javid Moslehi, Yuzhi Chen, Vincent Chau, Margaret A Read, William G. Kaelin> ;EMBO Reports. 2002 Feb 1
• Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor alpha subunit revealed in the presence of th...
  Kanno T, Kanno Y, Chen LF, Ogawa E, Kim WY, Ito Y> ;Mol. Cell. Biol.. 1998-05-01
• Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L.
  Watkins, D., Ru, M., Hwang, H. Y., Kim, C. D., Murray, A., Philip, N. S., Kim, W., Legakis, H., Wai, T., Hilton, J. F., Ge, B., Doré, C., Hosack, A., Wilson, A., Grave...> ;Am J Hum Genet. 2002 Jul
• An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells.
  Nikitin, P. A., Yan, C. M., Forte, E., Bocedi, A., Tourigny, J. P., White, R. E., Allday, M. J., Patel, A., Dave, S. S., Kim, W., Hu, K., Guo, J., Tainter, D., Rusyn, ...> ;Cell Host Microbe. 2010 Dec 16
• A multidisciplinary approach to the management of urologic malignancies: does it influence diagnostic and treatment decisions?
  Kurpad, R., Kim, W., Rathmell, W. K., Godley, P., Whang, Y., Fielding, J., Smith, L., Pettiford, A., Schultz, H., Nielsen, M., Wallen, E. M., Pruthi, R. S.> ;Urol Oncol. 2011 Jul 01
• The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer.
  Kim, W., Kaelin, W. G.> ;Curr Opin Genet Dev. 2003 Feb
• Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.
  Li, M., Kim, W. Y.> ;J Cell Mol Med. 2011 Feb
• HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer.
  Jackson, A. L., Zhou, B., Kim, W. Y.> ;Expert Opin Ther Targets. 2010 Oct
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