YarivJHouvrasMD

PubMed

• Depletion ofresults in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome.
  Yaseswini Neelamraju, Evisa Gjini, Sagar Chhangawala, Hao Fan, Shuning He, Chang-Bin Jing, Ashley T Nguyen, Subhash Prajapati, Caroline Sheridan, Yariv Houvras, Ari Me...> ;Frontiers in Hematology. 2023 Jan 1
• 2 citations
  A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish.
  Jillian L Ellis, Kimberley J Evason, Changwen Zhang, Makenzie N Fourman, Jiandong Liu, Nikolay Ninov, Marion Delous, Benoit Vanhollebeke, Ian Fiddes, Jessica P Otis, Y...> ;Hepatology Communications. 2022 Nov 1
• 42 citations
  Safety and efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer including as first-line therapy: update from the ARROW trial.
  F Griesinger, G Curigliano, M Thomas, V Subbiah, C S Baik, D S W Tan, D H Lee, D Misch, E Garralda, D-W Kim, A J van der Wekken, J F Gainor, L Paz-Ares, S V Liu, G P K...> ;Annals of Oncology. 2022 Nov 1
• 6 citations
  Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
  Renuka Raman, Jacques A Villefranc, Timothy M Ullmann, Jessica Thiesmeyer, Viviana Anelli, Jun Yao, James R Hurley, Chantal Pauli, Rohan Bareja, Kenneth Wha Eng, Princ...> ;The Journal of Experimental Medicine. 2022 Jun 6
• 3 citations
  PPP6C, a serine-threonine phosphatase, regulates melanocyte differentiation and contributes to melanoma tumorigenesis through modulation of MITF activity.
  Carolyn R Maskin, Renuka Raman, Yariv Houvras> ;Scientific Reports. 2022 Apr 2
• 9 citations
  RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.
  Timothy M Ullmann, Jessica W Thiesmeyer, Yeon Joo Lee, Shaham Beg, Juan Miguel Mosquera, Olivier Elemento, Thomas J Fahey 3rd, Theresa Scognamiglio, Yariv Houvras> ;Annals of Surgical Oncology. 2022 Mar 1
• 3 citations
  Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms.
  Sara E DiNapoli, Raúl Martinez-McFaline, Hao Shen, Ashley S Doane, Alexendar R Perez, Akanksha Verma, Amanda Simon, Isabel Nelson, Courtney A Balgobin, Caitlin T Bourq...> ;Frontiers in Cell and Developmental Biology. 2022 Jan 1
• 8 citations
  Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Te...
  Wael Al Zoughbi, Jesse Fox, Shaham Beg, Eniko Papp, Erika Hissong, Kentaro Ohara, Laurel Keefer, Michael Sigouros, Troy Kane, Daniel Bockelman, Donna Nichol, Emily Pat...> ;The Oncologist. 2021 Aug 4
• 24 citations
  Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
  Olivia Weeks, Gabriel D. Bossé, Isaac M. Oderberg, Sebastian Akle, Yariv Houvras, Paul J. Wrighton, Kyle A. LaBella, Isabelle Iversen, Sahar Tavakoli, Isaac Adatto, Ar...> ;The Journal of Clinical Investigation. 2020 May 1
• 24 citations
  Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair.
  Sara E DiNapoli, Raul Martinez-McFaline, Caitlin K Gribbin, Paul J. Wrighton, Courtney A Balgobin, Isabel Nelson, Abigail Leonard, Carolyn R Maskin, Arkadi Shwartz, El...> ;Nucleic Acids Research. 2020 Apr 17
• 14 citations
  Oxidative Phosphorylation Promotes Primary Melanoma Invasion
  Amel Salhi, Alexander C. Jordan, Irineu Illa Bochaca, Allison Izsak, Farbod Darvishian, Yariv Houvras, Keith M. Giles, Iman Osman> ;The American Journal of Pathology. 2020 Mar 3
• 41 citations
  Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.
  Sahar Nissim, Ignaty Leshchiner, Joseph D. Mancias, Matthew B. Greenblatt, Ophélia Maertens, Christopher A. Cassa, Jill A. Rosenfeld, Andrew G. Cox, John Hedgepeth, Ju...> ;Nature Genetics. 2019 Aug 12
• 62 citations
  Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferat...
  Saireudee Chaturantabut, Arkadi Shwartz, Kimberley J. Evason, Andrew G. Cox, Kyle A. LaBella, Arnout G Schepers, Song Yang, Mariana Acuña, Yariv Houvras, Liliana Manci...> ;Gastroenterology. 2019 May 1
• 69 citations
  Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth
  Andrew G. Cox, Allison Tsomides, Dean Yimlamai, Katie L. Hwang, Joel B. Miesfeld, Giorgio G. Galli, Brendan H. Fowl, Michael Fort, Kimberly Y Ma, Mark R. Sullivan, Aar...> ;The EMBO Journal. 2018 Nov 15
• 34 citations
  Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma
  Arvind M. Venkatesan, Rajesh Vyas, Alec K. Gramann, Karen Dresser, Sharvari Gujja, Sanchita Bhatnagar, Sagar Chhangawala, Camilla Borges Ferreira Gomes, Hualin Simon X...> ;The Journal of Clinical Investigation. 2018 Jan 2
• 47 citations
  Identification and characterization of T reg-like cells in zebrafish.
  Melissa Kasheta, Corrie A. Painter, Finola E. Moore, Riadh Lobbardi, Alysia Bryll, Eli Freiman, David L. Stachura, Arlin B. Rogers, Yariv Houvras, David M. Langenau, C...> ;The Journal of Experimental Medicine. 2017 Dec 4
• 37 citations
  Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression
  Viviana Anelli, Jacques A. Villefranc, Sagar Chhangawala, Eleonora Riva, Anvy Nguyen, Akanksha Verma, Rohan Bareja, Zhengming Chen, Theresa Scognamiglio, Olivier Eleme...> ;Elife. 2017 Mar 28
• 17 citations
  Completing the Arc: Targeted Inhibition of RET in Medullary Thyroid Cancer
  Yariv Houvras> ;Journal of Clinical Oncology. 2012 Jan 10
• 37 citations
  Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis
  Andrew G. Cox, Allison Tsomides, Andrew J. Kim, Diane C. Saunders, Katie L. Hwang, Kimberley J. Evason, Jerry R. Heidel, Kristin K. Brown, Min Yuan, Evan C. Lien, Byun...> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep 20
• 152 citations
  Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth
  Andrew G. Cox, Katie L. Hwang, Kristin K. Brown, Kimberley J. Evason, Sebastian Beltz, Allison Tsomides, Keelin O’Connor, Giorgio G. Galli, Dean Yimlamai, Sagar Chhang...> ;Nature Cell Biology. 2016 Aug 1
• 69 citations
  Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish.
  Qin Tang, John C. Moore, Myron S. Ignatius, Inês M. Tenente, Madeline N. Hayes, Elaine G. Garcia, Nora Torres Yordán, Caitlin Bourque, Shuning He, Jessica S. Blackburn...> ;Nature Communications. 2016 Jan 21
• 4 citations
  Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discovery.
  Craig J. Ceol, Yariv Houvras> ;Advances in Experimental Medicine and Biology. 2016 Jan 1
• 139 citations
  SPOP mutation leads to genomic instability in prostate cancer
  Gunther Boysen, Christopher E. Barbieri, Davide Prandi, Mirjam Blattner, Sung-Suk Chae, Arun Dahija, Srilakshmi Nataraj, Dennis Huang, Clarisse Marotz, Limei M. Xu, Ju...> ;Elife. 2015 Sep 16
• Multiplexing of ChIP-Seq Samples in an Optimized Experimental Condition Has Minimal Impact on Peak Detection
  Thadeous J. Kacmarczyk, Caitlin Bourque, Xihui Zhang, Yanwen Jiang, Yariv Houvras, Alicia Alonso, Doron Betel> ;Plos One. 2015 Jun 11
• 21 citations
  RSK1 Activation Promotes Invasion in Nodular Melanoma
  Amel Salhi, Joshua A. Farhadian, Keith M. Giles, Eleazar Vega-Saenz de Miera, Ines Pires da Silva, Caitlin Bourque, Karen Yeh, Sagar Chhangawala, Jinhua Wang, Fei Ye, ...> ;The American Journal of Pathology. 2015 Mar 1
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Journal Articles

• Oxidative Phosphorylation Promotes Primary Melanoma Invasion  
  Farbod Darvishian, Yariv Houvras, The American Journal of Pathology