AlanMHanashMD

PubMed

• 1 citations
  Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage.
  Viktor Arnhold, Winston Y Chang, Suze A Jansen, Govindarajan Thangavelu, Marco Calafiore, Paola Vinci, Ya-Yuan Fu, Takahiro Ito, Shuichiro Takashima, Anastasiya Egorov...> ;The Journal of Clinical Investigation. 2024 Feb 13
• 1 citations
  A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury.
  Marco Calafiore, Ya-Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Y Chang, Suze A Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonat...> ;Nature Communications. 2023 Sep 5
• 3 citations
  Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse.
  Susan DeWolf, Yuval Elhanati, Katherine Nichols, Nicholas R Waters, Chi L Nguyen, John B Slingerland, Natasia Rodriguez, Olga Lyudovyk, Paul A Giardina, Anastasia I Ko...> ;Science Translational Medicine. 2023 Jul 26
• 13 citations
  A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract.
  Doris M Ponce, Amin M Alousi, Ryotaro Nakamura, John Slingerland, Marco Calafiore, Karamjeet S Sandhu, Juliet N Barker, Sean Devlin, Jinru Shia, Sergio Giralt, Miguel-...> ;Blood. 2023 Mar 23
• 8 citations
  Challenges and opportunities targeting mechanisms of epithelial injury and recovery in acute intestinal graft-versus-host disease.
  Suze A Jansen, Edward E S Nieuwenhuis, Alan M Hanash, Caroline A Lindemans> ;Mucosal Immunology. 2022 Apr 1
• 52 citations
  National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report.
  Daniel Wolff, Vedran Radojcic, Robert Lafyatis, Resat Cinar, Rachel K. Rosenstein, Edward W. Cowen, Guang-Shing Cheng, Ajay Sheshadri, Anne Bergeron, Kirsten M. Willia...> ;Transplantation and Cellular Therapy. 2021 Oct 1
• 31 citations
  The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
  Robert A. Saxton, Lukas T. Henneberg, Marco Calafiore, Leon Su, Kevin Jude, Alan M. Hanash, K. Christopher Garcia> ;Immunity. 2021 Apr 13
• 24 citations
  High progression-free survival after intermediate intensity double unit cord blood transplantation in adults
  Juliet N. Barker, Sean M. Devlin, Kristine Naputo, Kelcey Skinner, Molly Maloy, Lisa Flynn, Theodora Anagnostou, Scott T. Avecilla, Andromachi Scaradavou, Christina Ch...> ;Blood Advances. 2020 Dec 8
• 129 citations
  Off-the-shelf EBV-specific T cell immunotherapy for rituximab-refractory EBV-associated lymphoma following transplantation
  Susan E. Prockop, Ekaterina Doubrovina, Stephanie Suser, Glenn Heller, Juliet N. Barker, Parastoo B. Dahi, Miguel Perales, Esperanza B. Papadopoulos, Craig S. Sauter, ...> ;The Journal of Clinical Investigation. 2020 Feb 3
• 78 citations
  T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage
  Shuichiro Takashima, Maria Laura Martin, Suze A. Jansen, Ya-Yuan Fu, Joris Bos, Daniel J. Chandra, Margaret O'Connor, Anna Mertelsmann, Paola Vinci, Jason Kuttiyara, S...> ;Science Immunology. 2019 Dec 6
• 56 citations
  T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.
  Ya-Yuan Fu, Anastasiya Egorova, Catherine Sobieski, Jason Kuttiyara, Marco Calafiore, Shuichiro Takashima, Hans Clevers, Alan M. Hanash> ;Immunity. 2019 Jul 16
• 2 citations
  BCL6 inhibition: a chronic GVHD twofer
  Paola Vinci, Alan M. Hanash> ;Blood. 2019 Jan 3
• 24 citations
  Nrf2 regulates CD4+ T cell-induced acute graft-versus-host disease in mice.
  Jennifer Tsai, Enrico Velardi, Yusuke Shono, Kimon V. Argyropoulos, Amanda M. Holland, Odette M. Smith, Nury L. Yim, Uttam K. Rao, Fabiana M Kreines, Sophie Lieberman,...> ;Blood. 2018 Dec 27
• 85 citations
  Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance
  Clarissa Campbell, Stanislav Dikiy, Shakti K. Bhattarai, Takatoshi Chinen, Fanny Matheis, Marco Calafiore, Beatrice Hoyos, Alan M. Hanash, Daniel Mucida, Vanni Bucci, ...> ;Immunity. 2018 Jun 19
• 1 citations
  Corrigendum: Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.
  Enrico Velardi, Jennifer Tsai, Stefan Radtke, Kirsten Cooper, Kimon V. Argyropoulos, Shieh Jae-Hung, Lauren F. Young, Amina Lazrak, Odette M. Smith, Sophie Lieberman, ...> ;Nature Medicine. 2018 Apr 1
• 78 citations
  Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
  Tobias Wertheimer, Enrico Velardi, Jennifer Tsai, Kirsten Cooper, Shiyun Xiao, Christopher C. Kloss, Katja J. Ottmüller, Zeinab Mokhtari, Christian Brede, Paul DeRoos,...> ;Science Immunology. 2018 Jan 12
• 28 citations
  Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury
  Enrico Velardi, Jennifer Tsai, Stefan Radtke, Kirsten Cooper, Kimon V. Argyropoulos, Shieh Jae-Hung, Lauren F. Young, Amina Lazrak, Odette M. Smith, Sophie Lieberman, ...> ;Nature Medicine. 2018 Jan 8
• 1 citations
  The enteric virome in hematopoietic stem cell transplantation: ready for its close-up.
  Shuichiro Takashima, Alan M. Hanash> ;Nature Medicine. 2017 Sep 1
• 45 citations
  Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.
  Jarrod A Dudakov, Anna Mertelsmann, Margaret O'Connor, Robert R. Jenq, Enrico Velardi, Lauren F. Young, Odette M. Smith, Richard L. Boyd, Marcel R.M. van den Brink, Al...> ;Blood. 2017 Aug 17
• 217 citations
  Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
  Jie He, Omar Abdel-Wahab, Michelle Nahas, Kai Wang, Raajit K. Rampal, Andrew M. Intlekofer, Jay Patel, Andrei V. Krivstov, Garrett M. Frampton, Lauren Young, Shan Zhon...> ;Blood. 2016 Jun 16
• 96 citations
  RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury
  Julius C. Fischer, Michael Bscheider, Gabriel Eisenkolb, Chia-Ching Lin, Alexander Wintges, Vera Otten, Caroline A. Lindemans, Simon Heidegger, Martina Rudelius, Sebas...> ;Science Translational Medicine. 2017 Apr 19
• 157 citations
  Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity
  Arnab Ghosh, Melody Smith, Scott E. James, Marco L. Davila, Enrico Velardi, Kimon V. Argyropoulos, Gertrude Gunset, Fabiana Perna, Fabiana M Kreines, Emily R Levy, Sop...> ;Nature Medicine. 2017 Feb 1
• 15 citations
  Role of the intestinal mucosa in acute gastrointestinal GVHD
  Jonathan U. Peled, Alan M. Hanash, Robert R. Jenq> ;Hematology. American Society of Hematology. Education Program. 2016 Dec 2
• 31 citations
  Role of the intestinal mucosa in acute gastrointestinal GVHD.
  Jonathan U. Peled, Alan M. Hanash, Robert R. Jenq> ;Blood. 2016 Nov 17
• 12 citations
  Correction: Corrigendum: Gut microbiome–derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease
  Nathan Mathewson, Robert R. Jenq, Anna V. Mathew, Mark J. Koenigsknecht, Alan M. Hanash, Tomomi Toubai, Katherine Oravecz-Wilson, Shin-Rong Wu, Yaping Sun, Corinne Ros...> ;Nature Immunology. 2016 Oct 1
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Abstracts/Posters

• Graft Versus Host Disease Leads to Elimination of Tissue-Resident Innate Lymphoid Cells Following Experimental and Clinical Allogeneic Transplantation
  Alan M. Hanash, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Mitochondrial Complex II in Intestinal Epithelial Cells Is a Critical Metabolic Checkpoint That Regulates Severity of Gastrointestinal Graft-Versus-Host Disease
  Alan M. Hanash, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Genome Editing for Transplantation and Cellular Therapies 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019