AndrewChowMD

PubMed

• Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies.
  Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Hongyao Xie, Nayan Jain, Taha Merghoub, Michel Sadelain, Mohamad Hamieh, Karlo Perica, Andrew Chow, Jedd D Wolchok> ;Nature Cancer. 2024 Mar 19
• 3 citations
  Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer.
  Danish Memon, Adam J Schoenfeld, Darwin Ye, George Fromm, Hira Rizvi, Xiang Zhang, Mohamed Reda Keddar, Divij Mathew, Kyung Jin Yoo, Jingya Qiu, Jayon Lihm, Jayalaksmi...> ;Cancer Cell. 2024 Feb 12
• Role of CD38 in anti-tumor immunity of small cell lung cancer.
  Hirokazu Taniguchi, Shweta S Chavan, Hiroshi Mukae, Triparna Sen, Andrew Chow, Joseph M Chan, Charles M Rudin> ;Frontiers in Immunology. 2024 Jan 1
• Spontaneous Bilateral Chylothorax Development During Alectinib Therapy for-Rearranged NSCLC-A Case Report.
  Sunanjay Bajaj, Andrew Chow, Alexander Drilon, Or Kalchiem-Dekel> ;JTO Clinical and Research Reports. 2023 Dec 1
• 2 citations
  Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.
  Alvaro Quintanal-Villalonga, Vidushi Durani, Amin Sabet, Esther Redin, Kenta Kawasaki, Moniquetta Shafer, Wouter R Karthaus, Samir Zaidi, Yingqian A Zhan, Parvathy Man...> ;Science Translational Medicine. 2023 Aug 2
• 1 citations
  Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector.
  Nicholas Ceglia, Zachary Sethna, Samuel S Freeman, Florian Uhlitz, Viktoria Bojilova, Nicole Rusk, Bharat Burman, Andrew Chow, Sohrab Salehi, Farhia Kabeer, Samuel Apa...> ;Nature Communications. 2023 Jul 20
• 11 citations
  Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation.
  Charles M Rudin, David Balli, W Victoria Lai, Allison L Richards, Evelyn Nguyen, Jacklynn V Egger, Noura J Choudhury, Triparna Sen, Andrew Chow, John T Poirier, Willia...> ;Journal of Thoracic Oncology. 2023 Sep 1
• 13 citations
  Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer.
  Arvind Ravi, Matthew D Hellmann, Monica B Arniella, Mark Holton, Samuel S Freeman, Vivek Naranbhai, Chip Stewart, Ignaty Leshchiner, Jaegil Kim, Yo Akiyama, Aaron T Gr...> ;Nature Genetics. 2023 May 1
• 18 citations
  The ectonucleotidase CD39 identifies tumor-reactive CD8T cells predictive of immune checkpoint blockade efficacy in human lung cancer.
  Chow, A., Uddin, F., Liu, M., Dobrin, A., Nabet, B., Mangarin, L., Lavin, Y., Rizvi, H., Tischfield, S., Quintanal-Villalonga, A., Chan, J., Shah, N., Allaj, V., Manoj...> ;Immunity. 2023 Jan 10
• Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq.
  Álvaro Quintanal-Villalonga, Joseph M Chan, Ignas Masilionis, Vianne Ran Gao, Yubin Xie, Viola Allaj, Andrew Chow, John T Poirier, Dana Pe'er, Charles M Rudin, Linas M...> ;STAR Protocols. 2022 Dec 16
• 157 citations
  Clinical implications of T cell exhaustion for cancer immunotherapy.
  Andrew Chow, Karlo Perica, Christopher A Klebanoff, Jedd D Wolchok> ;Nature Reviews. Clinical Oncology. 2022 Dec 1
• 23 citations
  Targeting Lysine-Specific Demethylase 1 Rescues Major Histocompatibility Complex Class I Antigen Presentation and Overcomes Programmed Death-Ligand 1 Blockade Resistan...
  Evelyn M Nguyen, Hirokazu Taniguchi, Joseph M Chan, Yingqian A Zhan, Xiaoping Chen, Juan Qiu, Elisa de Stanchina, Viola Allaj, Nisargbhai S Shah, Fathema Uddin, Parvat...> ;Journal of Thoracic Oncology. 2022 Aug 1
• 8 citations
  Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.
  Sara E Schad, Andrew Chow, Levi Mangarin, Heng Pan, Jiajia Zhang, Nicholas Ceglia, Justina X Caushi, Nicole Malandro, Roberta Zappasodi, Mathieu Gigoux, Daniel Hirschh...> ;The Journal of Experimental Medicine. 2022 Jun 6
• 36 citations
  WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC.
  Hirokazu Taniguchi, Rebecca Caeser, Shweta S Chavan, Yingqian A Zhan, Andrew Chow, Parvathy Manoj, Fathema Uddin, Hidenori Kitai, Rui Qu, Omar Hayatt, Nisargbhai S Sha...> ;Cell Reports. 2022 May 17
• 13 citations
  Inhibition of XPO1 sensitizes small cell lung cancer to first- and second-line chemotherapy.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yuan Hao, Andrew Chow, Yingqian Zhan, Shweta S Chavan, Fathema Uddin, Viola Allaj, P. Manoj, Nisargbhai S. Shah, Josep...> ;Cancer Research. 2021 Nov 23
• Insights from prospective multi-omic profiling of lymphocytes in resected lung cancer.
  Andrew Chow, Matthew D. Hellmann> ;Annals of Oncology. 2021 Oct 26
• 22 citations
  Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Zhan, Maysun Hasan, Shweta S. Chavan, Fanli Meng, Fathema Uddin, Viola Allaj, P. Manoj, Nisargbhai S. Shah, J...> ;Journal of Hematology & Oncology. 2021 Oct 16
• 118 citations
  Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer
  Joseph M. Chan, Álvaro Quintanal-Villalonga, Vianne R. Gao, Yubin Xie, Viola Allaj, Ojasvi Chaudhary, Ignas Masilionis, Jacklynn V. Egger, Andrew Chow, Thomas Walle, M...> ;Cancer Cell. 2021 Nov 8
• 110 citations
  Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
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• 85 citations
  Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Cancer Cell. 2021 Jul 12
• 50 citations
  Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation.
  Álvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Zhan, Maysun Hasan, Shweta S Chavan, Fanli Meng, Fathema Uddin, P. Manoj, Mark T.A. Donoghue, Helen Won, Jose...> ;Cancer Discovery. 2021 Jun 21
• 26 citations
  MET Exon 14-altered Lung Cancers and MET Inhibitor Resistance.
  Robin Guo, M. Offin, A. Rose Brannon, Jason C. Chang, Andrew Chow, Lukas Delasos, Jeffrey Girshman, Olivia Wilkins, Caroline G. McCarthy, Alex Makhnin, Christina Falco...> ;Clinical Cancer Research. 2021 Feb 1
• 39 citations
  ImmGen at 15
  Stephanie Vargas Aguilar, Oscar M Aguilar, Rhys S. Allan, El-ad David Amir, Veronique Angeli, Maxim N. Artyomov, Natasha Asinovski, Jilian Astarita, K. Frank Austen, G...> ;Nature Immunology. 2020 Jul 1
• 53 citations
  Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models
  Sai Kiran Sharma, Andrew Chow, Sebastien Monette, Delphine Vivier, Jacob Pourat, Kimberly J. Edwards, Thomas R. Dilling, Dalya Abdel-Atti, Brian M. Zeglis, John T. Poi...> ;Cancer Research. 2018 Apr 1
• 795 citations
  Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.
  Yonit Lavin, Soma Kobayashi, Andrew Leader, El-ad David Amir, Naama Elefant, Camille Bigenwald, Romain Remark, Robert Sweeney, Christian Becker, Jacob H. Levine, Klaus...> ;Cell. 2017 May 4
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