AtulBediMD

PubMed

• 50 citations
  Immune profiles in primary squamous cell carcinoma of the head and neck.
  Vassiliki Saloura, Evgeny Izumchenko, Zhixiang Zuo, Riyue Bao, Michael Korzinkin, Ivan V. Ozerov, Alex Zhavoronkov, David Sidransky, Atul Bedi, Mohammad O. Hoque, Hart...> ;Oral Oncology. 2019 Sep 1
• 221 citations
  Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy
  Rajani Ravi, Kimberly A. Noonan, Vui Pham, Rishi Bedi, Alex Zhavoronkov, Ivan V. Ozerov, Eugene Makarev, Artem V. Artemov, Piotr T. Wysocki, Ranee Mehra, Sridhar Nimma...> ;Nature Communications. 2018 Feb 21
• 53 citations
  SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells
  Hiroyuki Ozawa, Ruchira Ranaweera, Evgeny Izumchenko, Eugene Makarev, Alex Zhavoronkov, Elana J. Fertig, Jason D. Howard, Ana Markovic, Atul Bedi, Rajani Ravi, Jimena ...> ;Clinical Cancer Research. 2017 Sep 1
• 187 citations
  Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors
  Evgeny Izumchenko, K. Paz, D. Ciznadija, Ido Sloma, Amos Katz, David Vasquez-Dunddel, Ido Ben-Zvi, Justin Stebbing, William P. McGuire, William P. Harris, Robert G. Ma...> ;Annals of Oncology. 2017 Oct 1
• 22 citations
  In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia
  Eugene Makarev, Adrian D. Schubert, Riya R. Kanherkar, Nyall R. London, Mahder Teka, Ivan V. Ozerov, Ksenia Lezhnina, Atul Bedi, Rajani Ravi, Rannee Mehra, Mohammad O....> ;Cell Death Discovery. 2017 May 22
• 38 citations
  Patient-derived xenografts as tools in pharmaceutical development
  Evgeny Izumchenko, Juliet Meir, Atul Bedi, Piotr T. Wysocki, Mohammad O. Hoque, David Sidransky> ;Clinical Pharmacology and Therapeutics. 2016 Jun 1
• 110 citations
  Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA
  Evgeny Izumchenko, Xiaofei Chang, Mariana Brait, Elana J. Fertig, Luciane T. Kagohara, Atul Bedi, Luigi Marchionni, Nishant Agrawal, Rajani Ravi, Sian Jones, Mohammad ...> ;Nature Communications. 2015 Sep 16
• 42 citations
  A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma
  Jill Gilbert, Michael J. Schell, Xiuhua Zhao, Barbara A. Murphy, Tawee Tanvetyanon, Marino E. Leon, D. Neil Hayes, Missak Haigentz, Nabil F. Saba, Jorge Nieva, Justin ...> ;Oral Oncology. 2015 Apr 1
• 96 citations
  The TGFβ-miR200-Mig6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors
  Eugene Izumchenko, Xiaofei Chang, Christina Michailidi, Luciane T. Kagohara, Rajani Ravi, Keren Paz, Mariana Brait, Mohammad O. Hoque, Shizhang Ling, Atul Bedi, David ...> ;Cancer Research. 2014 Jul 15
• 26 citations
  The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors
  Xiaofei Chang, Eugene Izumchenko, Luisa M. Solis, Myoung Sook Kim, Aditi Chatterjee, Shizhang Ling, Constance L. Monitto, Paul M. Harari, Manuel Hidalgo, Steven N. Goo...> ;Plos One. 2013 Jul 31
• 52 citations
  Inhibition of TGF-β Enhances the In Vivo Antitumor Efficacy of EGF Receptor–Targeted Therapy
  Atul Bedi, Xiaofei Chang, Kimberly A. Noonan, Vui Pham, Rishi Bedi, Elana J. Fertig, Michael Considine, Joseph A. Califano, Ivan Borrello, Christine H. Chung, David Si...> ;Molecular Cancer Therapeutics. 2012 Aug 27
• 43 citations
  Adenylate kinase 3 sensitizes cells to cigarette smoke condensate vapor induced cisplatin resistance.
  Xiaofei Chang, Rajani Ravi, Vui Pham, Atul Bedi, Aditi Chatterjee, David Sidransky> ;Plos One. 2011 Jun 15
• 35 citations
  Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta.
  Aditi Chatterjee, Xiaofei Chang, Tanusree Sen, Rajani Ravi, Atul Bedi, David Sidransky> ;Cancer Research. 2010 Feb 15
• 36 citations
  Resistance of cancers to immunologic cytotoxicity and adoptive immunotherapy via X-linked inhibitor of apoptosis protein expression and coexisting defects in mitochond...
  Rajani Ravi, Ephraim J. Fuchs, Ajay N. Jain, Vui Pham, Kiyoshi Yoshimura, Traci S. Prouser, Sanju Jalla, Xianzheng Zhou, Elizabeth Garrett-Mayer, Scott H. Kaufmann, Ri...> ;Cancer Research. 2006 Feb 1
• 61 citations
  Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL
  Rajani Ravi, Ajay Jain, Richard D. Schulick, Vui Pham, Traci S. Prouser, Heather E. Allen, Elizabeth Garrett Mayer, Hua Yu, Drew M. Pardoll, Avi Ashkenazi, Atul Bedi> ;Cancer Research. 2004 Dec 15
• 106 citations
  NF-κB in cancer—a friend turned foe
  Rajani Ravi, Atul Bedi> ;Drug Resistance Updates. 2004 Feb 1
• On the TRAIL from death receptors to prostate cancer therapy.
  Atul Bedi> ;Cancer Biology & Therapy. 2002 Nov 1
• 11 citations
  Potential methods to circumvent blocks in apoptosis in lymphomas.
  Rajani Ravi, Atul Bedi> ;Current Opinion in Oncology. 2002 Sep 1
• 86 citations
  Sensitization of Tumor Cells to Apo2 Ligand/TRAIL-induced Apoptosis by Inhibition of Casein Kinase II
  Rajani Ravi, Atul Bedi> ;Cancer Research. 2002 Aug 1
• 112 citations
  Requirement of BAX for TRAIL/Apo2L-induced Apoptosis of Colorectal Cancers Synergism with Sulindac-mediated Inhibition of Bcl-xL
  Rajani Ravi, Atul Bedi> ;Cancer Research. 2002 Mar 15
• 109 citations
  Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apop...
  Guilian Niu, Kenneth H. Shain, Mei Huang, Rajani Ravi, Atul Bedi, William S. Dalton, Richard Jove, Hua Yu> ;Cancer Research. 2001 Apr 15
• 264 citations
  Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB.
  Rajani Ravi, Gauri. C. Bedi, Laura W. Engstrom, Qinwen Zeng, Bijoyesh Mookerjee, Céline Gélinas, Ephraim J. Fuchs, Atul Bedi> ;Nature Cell Biology. 2001 Apr 1
• 156 citations
  'The metabolism of tumours': 70 years later.
  Gregg L. Semenza, Dmitri Artemov, Atul Bedi, Zaver M. Bhujwalla, Kelly Chiles, David M. Feldser, Erik Laughner, Rajani Ravi, Jonathan W. Simons, Panthea Taghavi, Hua Z...> ;Novartis Foundation Symposium. 2001 Jan 1
• 918 citations
  Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
  Rajani Ravi, Bijoyesh Mookerjee, Zaver M. Bhujwalla, Carrie Hayes Sutter, Dmitri Artemov, Qinwen Zeng, Larry E. Dillehay, Ashima Madan, Gregg L. Semenza, Atul Bedi> ;Genes & Development. 2000 Jan 1
• 9 citations
  Philadelphia chromosome-negative engraftment after autologous transplantation with granulocyte-macrophage colony-stimulating factor for chronic myeloid leukemia.
  Douglas E. Gladstone, Atul Bedi, Carole B. Miller, Stephen J. Noga, Constance A. Griffin, Steven Piantadosi, Pablo J. Cagnoni, Robert A. Brodsky, B. Douglas Smith, Tra...> ;Biology of Blood and Marrow Transplantation. 1999 Dec 1
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