CraigBThompsonMD

PubMed

• Oncogenic Control of Metabolism.
  Natalya N Pavlova, Craig B Thompson> ;Cold Spring Harbor Perspectives in Medicine. 2024 Apr 2
• 6 citations
  A century of the Warburg effect.
  Craig B Thompson, Karen H Vousden, Randall S Johnson, Willem H Koppenol, Helmut Sies, Zhimin Lu, Lydia W S Finley, Christian Frezza, Jiyeon Kim, Zeping Hu, Caroline R ...> ;Nature Metabolism. 2023 Nov 1
• 12 citations
  Lactate activates the mitochondrial electron transport chain independently of its metabolism.
  Xin Cai, Charles P Ng, Olivia Jones, Tak Shun Fung, Keun Woo Ryu, Dayi Li, Craig B Thompson> ;Molecular Cell. 2023 Nov 2
• Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
  Juan-Manuel Schvartzman, Grace Forsyth, Henry Walch, Walid Chatila, Angelo Taglialatela, Brian J Lee, Xiaolu Zhu, Steven Gershik, Francesco V Cimino, Anthony Santella,...> ;Molecular Cell. 2023 Jul 6
• 11 citations
  A tissue injury sensing and repair pathway distinct from host pathogen defense.
  Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M Bilate, Kevin Andrew Uy Gonzales, S Martina Parigi, Christopher J Cowley, Brian Hurwitz, Ji...> ;Cell. 2023 May 11
• 13 citations
  Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell-Derived Cytokines.
  Simon Schwörer, Francesco V Cimino, Manon Ros, Kaloyan M Tsanov, Charles Ng, Scott W Lowe, Carlos Carmona-Fontaine, Craig B Thompson> ;Cancer Research. 2023 May 15
• 2 citations
  Activating mTOR Mutations Are Detrimental in Nutrient-Poor Conditions.
  Agata A Bielska, Caitlin F Harrigan, Yeon Ju Kyung, Quaid Morris, Wilhelm Palm, Craig B Thompson> ;Cancer Research. 2022 Sep 16
• 7 citations
  Hyperpolarized [5-C,4,4-H,5-N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine.
  Roozbeh Eskandari, Nathaniel Kim, Arsen Mamakhanyan, Michelle Saoi, Guannan Zhang, Marjan Berisaj, Kristin L Granlund, Alex J Poot, Justin Cross, Craig B Thompson, Kay...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 May 10
• 10 citations
  Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging.
  Sui Seng Tee, Nathaniel Kim, Quinlan Cullen, Roozbeh Eskandari, Arsen Mamakhanyan, Rami M Srouji, Rachel Chirayil, Sangmoo Jeong, Mojdeh Shakiba, Edward R Kastenhuber,...> ;Science Advances. 2022 Apr 8
• 9 citations
  A mitochondrial long-chain fatty acid oxidation defect leads to transfer RNA uncharging and activation of the integrated stress response in the mouse heart.
  Pablo Ranea-Robles, Natalya N Pavlova, Aaron Bender, Andrea S Pereyra, Jessica M Ellis, Brandon Stauffer, Chunli Yu, Craig B Thompson, Carmen Argmann, Michelle Puchowi...> ;Cardiovascular Research. 2022 Dec 29
• 336 citations
  The hallmarks of cancer metabolism: Still emerging.
  Natalya N Pavlova, Jiajun Zhu, Craig B Thompson> ;Cell Metabolism. 2022 Mar 1
• 9 citations
  Leucine retention in lysosomes is regulated by starvation.
  Urmi Bandyopadhyay, Pavlina Todorova, Natalya N Pavlova, Yuma Tada, Craig B Thompson, Lydia W S Finley, Michael Overholtzer> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Feb 8
• 23 citations
  Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment.
  Simon Schwörer, Natalya N. Pavlova, Francesco V Cimino, Bryan King, Xin Cai, Gina M. Sizemore, Craig B. Thompson> ;Nature Metabolism. 2021 Nov 1
• 16 citations
  Inducible and reversible inhibition of miRNA-mediated gene repression in vivo.
  Gaspare La Rocca, Bryan King, Bing Shui, Xiaoyi Li, Minsi Zhang, Kemal M. Akat, Paul Ogrodowski, Chiara Mastroleo, Kevin Chen, Vincenzo Cavalieri, Yilun Ma, Viviana An...> ;Elife. 2021 Aug 31
• 14 citations
  Improving Goal Concordant Care Among 10 Leading Academic U.S. Cancer Hospitals: A Collaboration of the Alliance of Dedicated Cancer Centers.
  Kristen K. McNiff, Michael A. Caligiuri, Nancy E. Davidson, William B. Farrar, Richard I. Fisher, Laurie H. Glimcher, Rodney B. Hanners, Patrick Hwu, Candace S. Johnso...> ;The Oncologist. 2021 Jul 1
• 57 citations
  Mitochondrial NADP(H) generation is essential for proline biosynthesis
  Jiajun Zhu, Simon Schwörer, Mirela Berisa, Yeon Ju Kyung, Keun Woo Ryu, Junmei Yi, Xuejun Jiang, Justin R. Cross, Craig B. Thompson> ;Science. 2021 May 28
• 23 citations
  Translation in amino-acid-poor environments is limited by tRNAGln charging.
  Natalya N. Pavlova, Bryan King, Rachel H Josselsohn, Sara Violante, Victoria L Macera, Santosha Vardhana, Justin R. Cross, Craig B. Thompson> ;Elife. 2020 Dec 8
• 378 citations
  Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis
  Junmei Yi, Jiajun Zhu, Jiao Wu, Craig B. Thompson, Xuejun Jiang> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Dec 8
• 27 citations
  Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis.
  Bryan King, Jingwen Araki, Wilhelm Palm, Craig B. Thompson> ;Genes & Development. 2020 Oct 1
• 4 citations
  Training in high-risk coronary procedures and interventions: Recommendations for core competencies
  Rhian E. Davies, Khaldoon Alaswad, Robert F. Riley, Perwaiz Meraj, Craig B. Thompson, Arasi Maran, Dimitri Karmpaliotis, James M. McCabe, Ajay J. Kirtane, William Lomb...> ;Catheterization and Cardiovascular Interventions. 2021 Apr 1
• 201 citations
  Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.
  Santosha Vardhana, Madeline A. Hwee, Mirela Berisa, Daniel K. Wells, Kathryn E. Yost, Bryan King, Melody Smith, Pamela S. Herrera, Howard Y. Chang, Ansuman T. Satpathy...> ;Nature Immunology. 2020 Jul 13
• 86 citations
  Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress
  Simon Schwörer, Mirela Berisa, Sara Violante, Weige Qin, Jiajun Zhu, Ronald C. Hendrickson, Justin R. Cross, Craig B. Thompson> ;The EMBO Journal. 2020 Apr 15
• 43 citations
  Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism.
  Albert M. Li, Gregory S. Ducker, Yang Li, Jose A. Seoane, Yiren Xiao, Stavros Melemenidis, Yiren Zhou, Ling Liu, Sakari Vanharanta, Edward E. Graves, Erinn B. Rankin, ...> ;Molecular Cancer Research. 2020 Jan 15
• 14 citations
  Growth factors stimulate anabolic metabolism by directing nutrient uptake
  Craig B. Thompson, Agata A. Bielska> ;The Journal of Biological Chemistry. 2019 Nov 22
• 140 citations
  Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
  Jiajun Zhu, Mirela Berisa, Simon Schwörer, Weige Qin, Justin R. Cross, Craig B. Thompson> ;Cell Metabolism. 2019 Nov 5
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Journal Articles

• Acquired Resistance to IDH Inhibition Through Trans or Cis Dimer-Interface Mutations  
  Martin S Tallman, Eytan M Stein, Alan H Shih, Maria E Arcila, Andrew M Intlekofer, Craig B Thompson, Mikhail Roshal, Nature