DarleneJ.EliasMD

Pulmonology • La Jolla, CA

Pleural Disease

Physician

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Office
10666 N Torrey Pines Rd
# SV6
La Jolla, CA 92037
Phone+1 858-554-8860

Fax+1 858-554-8817
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Summary

Dr. Darlene Elias, MD is a pulmonologist in La Jolla, California. She is currently licensed to practice medicine in California. She is affiliated with Scripps Green Hospital and Naval Medical Center San Diego.

Education & Training

University of California (San Francisco)Residency, Internal Medicine, 1982 - 1983
Santa Clara Valley Medical CenterResidency, Internal Medicine, 1980 - 1982
University of California San Francisco School of MedicineClass of 1980

Certifications & Licensure

CA State Medical License 1981 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Top MD Consumers Checkbook
Super Doctor SuperDoctors.com

Publications & Presentations

PubMed

5 citations
An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms
Annette von Drygalski, Vikas Bhat, Andrew J. Gale, Patricia M. Averell, Thomas J. Cramer, Darlene J. Elias, John H. Griffin, Laurent O. Mosnier> ;Blood Advances. 2020 Aug 11
11 citations
Novel exomic rare variants associated with venous thrombosis.
Hiroshi Deguchi, Meenal Shukla, Mohammed Hayat, Ali Torkamani, Darlene J. Elias, John H. Griffin> ;British Journal of Haematology. 2020 Mar 30
3 citations
Plasma skeletal muscle myosin phenotypes identified by immunoblotting are associated with pulmonary embolism occurrence in young adults.
Taichi K. Deguchi, Hiroshi Deguchi, Zihan Guo, Darlene J. Elias, John H. Griffin> ;Thrombosis Research. 2020 Feb 27
3 citations
Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients.
José A. Fernández, Hiroshi Deguchi, Darlene J. Elias, John H. Griffin> ;Research and Practice in Thrombosis and Haemostasis. 2020 Feb 1
11 citations
Minor Plasma Lipids Modulate Clotting Factor Activities and May Affect Thrombosis Risk.
Hiroshi Deguchi, Darlene J. Elias, John H. Griffin> ;Research and Practice in Thrombosis and Haemostasis. 2017 Jun 20
6 citations
Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases.
Hiroshi Deguchi, Silvia Navarro, Amanda B. Payne, Darlene J. Elias, Nicole F. Dowling, Harland Austin, Francisco España, Pilar Medina, W. Craig Hooper, John H. Griffin> ;Research and Practice in Thrombosis and Haemostasis. 2017 Jun 23
12 citations
Elevated CETP Lipid Transfer Activity is Associated with the Risk of Venous Thromboembolism.
Hiroshi Deguchi, Yajnavalka Banerjee, Darlene J. Elias, John H. Griffin> ;Journal of Atherosclerosis and Thrombosis. 2016 May 9
53 citations
Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis
Julijana Ivanisevic, Darlene J. Elias, Hiroshi Deguchi, Patricia M. Averell, Michael E. Kurczy, Caroline H. Johnson, Ralf Tautenhahn, Zheng-Jiang Zhu, Jeramie D. Watro...> ;Scientific Reports. 2015 Aug 5
6 citations
Inhibition of thrombin generation in human plasma by phospholipid transfer protein
Hiroshi Deguchi, Gertrud Wolfbauer, Marian C. Cheung, Yajnavalka Banerjee, Darlene J. Elias, José A. Fernández, John J. Albers, John H. Griffin> ;Thrombosis Journal. 2015 Jul 16
39 citations
Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data
Hiroshi Deguchi, Yajnavalka Banerjee, Sunia A. Trauger, Gary Siuzdak, Ewa Kalisiak, José A. Fernández, Linh Hoang, Minerva Tran, Subramanian Yegneswaran, Darlene J. El...> ;Blood. 2015 Sep 24
8 citations
Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids.
Hiroshi Deguchi, Darlene J. Elias, Sunia A. Trauger, Hui-Min Zhang, Ewa Kalisiak, Gary Siuzdak, John H. Griffin> ;British Journal of Haematology. 2014 May 1
1 citations
Gain in translation: heme oxygenase-1 induced by activated protein C promotes thrombus resolution.
Hiroshi Deguchi, Darlene J. Elias, John H. Griffin> ;Journal of Thrombosis and Haemostasis. 2014 Jan 1
51 citations
Prevalence and risk factors for hypertension in hemophilia.
Annette von Drygalski, Nicholas A. Kolaitis, Ricki Bettencourt, Jaclyn Bergstrom, Rebecca Kruse-Jarres, Doris Quon, Christina L. Wassel, Ming C Li, Jill Waalen, Darlen...> ;Hypertension. 2013 Jul 1
15 citations
Elevated serum amyloid A is associated with venous thromboembolism
Hiroshi Deguchi, Darlene J. Elias, Silvia Navarro, Francisco España, John H. Griffin> ;Thrombosis and Haemostasis. 2012 Dec 20
396 citations
Engineered virus-like nanoparticles reverse heparin anticoagulation more consistently than protamine in plasma from heparin-treated patients.
Andrew J. Gale, Darlene J. Elias, Patricia M. Averell, Paul S. Teirstein, Mitchell Buck, Steven D. Brown, Zinaida Polonskaya, Andrew K. Udit, M. G. Finn> ;Thrombosis Research. 2011 Oct 1
5 citations
Association of Apo(a)Isoform Size with Dyslipoproteinemia in Male Venous Thrombosis Patients
Marian C. Cheung, John J. Albers, Hal Kennedy, Hiroshi Deguchi, Darlene J. Elias, Patricia M. Averell, John H. Griffin, Santica M. Marcovina> ;Clinica Chimica Acta; International Journal of Clinical Chemistry. 2010 Sep 6
16 citations
Elevated plasma fibronectin levels associated with venous thromboembolism.
Natalie M. Pecheniuk, Darlene J. Elias, Hiroshi Deguchi, Patricia M. Averell, John H. Griffin> ;Thrombosis and Haemostasis. 2008 Aug 1
6 citations
Warfarin Pharmacogenomics: A big step forward for individualized medicine: enlightened dosing of warfarin
Darlene J. Elias, Eric J Topol> ;European Journal of Human Genetics. 2008 Feb 27
24 citations
Failure to validate association of gene polymorphisms in EPCR, PAR-1, FSAP and protein S Tokushima with venous thromboembolism among Californians of European ancestry.
Natalie M. Pecheniuk, Darlene J. Elias, Xiao Xu, John H. Griffin> ;Thrombosis and Haemostasis. 2008 Feb 1
5 citations
Cholesteryl ester transfer protein genotypes associated with venous thrombosis and dyslipoproteinemia in males.
Natalie M. Pecheniuk, Hiroshi Deguchi, Darlene J. Elias, Xiao Xu, John H. Griffin> ;Journal of Thrombosis and Haemostasis. 2006 Sep 1
1 citations
Is adiponectin implicated in venous thromboembolism
José A. Fernández, Natalie M. Pecheniuk, Hiroshi Deguchi, Darlene J. Elias, John H. Griffin> ;Journal of Thrombosis and Haemostasis. 2006 May 1
131 citations
High-Density Lipoprotein Deficiency and Dyslipoproteinemia Associated With Venous Thrombosis in Men
Hiroshi Deguchi, Natalie M. Pecheniuk, Darlene J. Elias, Patricia M. Averell, John H. Griffin> ;Circulation. 2005 Aug 9
18 citations
T-Cell Receptor Biases and Clonal Proliferations in Blood and Pleural Effusions of Patients with Lung Cancer
Steven R. Duncan, Darlene J. Elias, Mihovil Roglic, Katherine W. Pekny, Argyrios N. Theofilopoulos> ;Human Immunology. 1997 Mar 1
34 citations
Pulmonary Hypertension Developing after Alglucerase Therapy in Two Patients with Type 1 Gaucher Disease Complicated by the Hepatopulmonary Syndrome
Arthur Dawson, Darlene J. Elias, David S. Rubenson, Stephen H. Bartz, P. Garver, Andrea C. Kay, Colin M. Bloor, Ernest Beutler> ;Annals of Internal Medicine. 1996 Dec 1
27 citations
T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis.
Steven R. Duncan, Vincent G. Valentine, Mihovil Roglic, Darlene J. Elias, Katherine W. Pekny, James Theodore, Dwight H. Kono, Argyrios N. Theofilopoulos> ;The Journal of Clinical Investigation. 1996 Jun 1
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Hospital Affiliations

Naval Medical Center San DiegoSan Diego, California
Scripps Green HospitalLa Jolla, California