
David Hoytema van Konijnenburg MD PhD
Pediatric Asthma & Allergic Conditions, Clinical & Laboratory Immunology
Attending Physician in Allergy and Immunology
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300 Longwood AveBoston, MA 02115
Phone+1 617-355-6000
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Summary
- MD PhD, completed PhD work in Immunology at Utrecht University, Van Wijk lab and The Rockefeller University, Mucida lab. My research focused on intestinal T cells using a combination of techniques including live imaging. Completed pediatrics residency at Boston Childrens Hospital and Harvard Medical School concurrent with research at Harvard Medical School, Kirchhausen lab, Zon lab, where I studied the development and function of tissue-resident immune cells whilst completing the Integrated Research Pathway.
Current Allergy and Immunology Attending Physician at Boston Children's Hospital and Instructor at Harvard Medical School, working in Nigrovic lab and Zanoni lab on tissue-resident immune cells in the lung. Clinically especially passionate about providing care for patients with immune dysregulation syndromes or immunodeficiency, with a focus on immunogenetics and research-based clinical care for patients with rare diseases of the immune system. Part of MIDAS Immune Dysregulation program and Interstitial Lung Diseases program at Boston Children's Hospital.
Education & Training
Boston Children’s HospitalFellowship, Allergy and Immunology, 2021 - 2024
Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 2018 - 2021
Utrecht University Graduate School of Life SciencesPhD, Immunology, Cum Laude, 2015 - 2018
Utrecht University Faculty of MedicineClass of 2014, MD, Cum Laude
Certifications & Licensure
MA State Medical License 2018 - 2026
American Board of Allergy and Immunology Allergy & Immunology
American Board of Pediatrics Pediatrics
Awards, Honors, & Recognition
- Faculty Development Award American Academy of Allergy, Asthma and Immunology, 2026
- Parker B. Francis Fellowship Francis Family Foundation, 2026
- Faculty Development Award Boston Children's Hospital, 2025
Publications & Presentations
PubMed
- Targeted deep sequencing identifies mosaicism in patients with immune dysregulation.Elizabeth G Schmitz, Alexander J Paul, Rajarshi Ghosh, Nermina Saucier, Ana Kolicheski
The Journal of Allergy and Clinical Immunology. 2026-05-01 - Systematic functional validation of IKAROS variants from patients and laboratory-generated mutations.Hye Sun Kuehn, Agustin A Gil Silva, Natchanun Klangkalya, Ana Esteve-Sole, Shubham Goel
Blood Advances. 2026-03-10 - Distinct Effects of Autologous Hematopoietic Stem Cell Transplantation on T Cell Composition and Profile in Refractory Crohn's Disease.Elise S Saager, Lisanne Lutter, Nofel Mahmmod, Eveline M Delemarre, David P Hoytema van Konijnenburg
Inflammatory Bowel Diseases. 2026-03-01
Press Mentions
An unexpected origin for calming immune cells in the gutMarch 19th, 2021
In brief: Immune cells surveil intestine to prevent infectionsMarch 19th, 2021
https://www.umcutrecht.nl/en/about-us/news/details/jun-8-special-immune-cells-in-the-intestinal-wall-play-a-role-in-chronic-intestinal-inflammationsMarch 19th, 2021
Grant Support
- Resetting regulatory T cell networks in Inflammatory Bowel DiseaseUniversity Medical Center Utrecht - Career Development - Alexandre Suerman MD/PhD Stipend (internal)2015–2018
- Intestinal Surveillance, Regulation and Recovery by Intraepithelial LymphocytesPrince Bernhard Cultural Foundation - Career Development - Grant2016–2017
- Intestinal Surveillance, Regulation and Recovery by Intraepithelial LymphocytesRoyal Netherlands Academy of Arts and Sciences - Career Development – Academy Ter Meulen Grant2016–2017
- Intestinal Surveillance by Intraepithelial LymphocytesHelmsley Charitable Trust / The Rockefeller University - Research - Pilot Project Award (internal)2014–2015
Professional Memberships
- Member
- Member
- Member
- Society for Pediatric ResearchJunior Member
- Massachusetts Medical SocietyMember
External Links
- LinkedIn Profilehttps://www.linkedin.com/in/davidhoytema/
- Harvard Catalyst Profilehttps://connects.catalyst.harvard.edu/Profiles/display/Person/169292
- Boston Children's Profilehttps://www.childrenshospital.org/directory/david-hoytema-van-konijnenburg
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