ErikStevenMusiekMD

PubMed

• Sleep and circadian biomarkers of postoperative delirium (SLEEP-POD): protocol for a prospective and observational cohort study.
  Elizabeth Sugg, Elizabeth Gleeson, Sarah N Baker, Peng Li, Chenlu Gao, Ariel Mueller, Hao Deng, Richa Saxena, Oluwaseun Akeju, Kun Hu, Shiqian Shen, Esteban Franco-Gar...> ;BMJ Open. 2024 Apr 19
• Editorial overview: Introduction to neurobiology of disease.
  Erik S Musiek, Eric J Nestler> ;Current Opinion in Neurobiology. 2024 Apr 11
• Longer Sleep Duration in Alzheimer's Disease Progression: A Compensatory Response?
  Peng Li, Brendan P Lucey, Kun Hu, Lei Gao, Yo-El S Ju, Erik S Musiek> ;Sleep. 2024 Apr 11
• 2 citations
  Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration.
  Patrick W Sheehan, Jessica N Haines, Pedro G Gomez, Adya Dhuler, Collin J Nadarajah, Brittany M Freeberg, Hemanth R Nelvagal, Mariko Izumo, Joseph S Takahashi, Jonatha...> ;JCI Insight. 2024 Jan 23
• Author Correction: Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice.
  Jiyeon Lee, Julie M Dimitry, Jong Hee Song, Minsoo Son, Patrick W Sheehan, Melvin W King, G Travis Tabor, Young Ah Goo, Mitchell A Lazar, Leonard Petrucelli, Erik S Mu...> ;Nature Communications. 2023 Nov 27
• 1 citations
  Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) coh...
  Turner, R., Polsinelli, A., Wonderlin, R., Hammers, D., Garcia, A., Eloyan, A., Taurone, A., Thangarajah, M., Beckett, L., Gao, S., Wang, S., Kirby, K., Logan, P., Ais...> ;Alzheimer's & Dementia. 2023 Nov 1
• 4 citations
  Profiling baseline performance on the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection.
  Turner, R., Dustin B Hammers, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Laurel Beckett, Sujuan Gao, Kala Kirby, Paul Aisen, Jeffrey L Dage, Tatiana Foroud, ...> ;Alzheimer's & Dementia. 2023 Nov 1
• Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.
  Turner, R., Jeffrey L Dage, Ani Eloyan, Maryanne Thangarajah, Dustin B Hammers, Anne M Fagan, Julia D Gray, Suzanne E Schindler, Casey Snoddy, Kelly N H Nudelman, Kell...> ;Alzheimer's & Dementia. 2023 Nov 1
• 1 citations
  White matter hyperintensities are higher among early-onset Alzheimer's disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Ear...
  Turner, R., Eloyan, A., Thangarajah, M., An, N., Borowski, B., Reddy, A., Aisen, P., Dage, J., Foroud, T., Ghetti, B., Griffin, P., Hammers, D., Iaccarino, L., Jack, C...> ;Alzheimer's & Dementia. 2023 Nov 1
• 1 citations
  The Sporadic Early-onset Alzheimer's Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) Cohort.
  Turner, R., Turner, R., Alexandra Touroutoglou, Yuta Katsumi, Michael Brickhouse, Alexander Zaitsev, Ryan Eckbo, Paul Aisen, Laurel Beckett, Jeffrey L Dage, Ani Eloyan...> ;Alzheimer's & Dementia. 2023 Nov 1
• Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.
  Turner, R., Bushnell, J., Hammers, D., Aisen, P., Dage, J., Eloyan, A., Foroud, T., Grinberg, L., Iaccarino, L., Jack, C., Kirby, K., Kramer, J., Koeppe, R., Kukull, W...> ;Alzheimer's & Dementia. 2023 Nov 1
• 7 citations
  Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
  Turner, R., Hanna Cho, Nidhi S Mundada, Liana G Apostolova, Maria C Carrillo, Ranjani Shankar, Alinda N Amuiri, Ehud Zeltzer, Charles C Windon, David N Soleimani-Meigo...> ;Alzheimer's & Dementia. 2023 Nov 1
• Pathogenic variants in the Longitudinal Early-onset Alzheimer's Disease Study cohort.
  Turner, R., Turner, R., Kelly N H Nudelman, Trever Jackson, Malia Rumbaugh, Ani Eloyan, Marco Abreu, Jeffrey L Dage, Casey Snoddy, Kelley M Faber, Tatiana Foroud, Dust...> ;Alzheimer's & Dementia. 2023 Nov 1
• 1 citations
  Learning slopes in early-onset Alzheimer's disease.
  Turner, R., Dustin B Hammers, Sára Nemes, Taylor Diedrich, Ani Eloyan, Kala Kirby, Paul Aisen, Joel Kramer, Kelly Nudelman, Tatiana Foroud, Malia Rumbaugh, Alireza Atr...> ;Alzheimer's & Dementia. 2023 Nov 1
• Time-restricted feeding and Alzheimer's disease: you are when you eat.
  Melvin W King, Yining Chen, Erik S Musiek> ;Trends in Molecular Medicine. 2023 Dec 1
• 4 citations
  Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice.
  Jiyeon Lee, Julie M Dimitry, Jong Hee Song, Minsoo Son, Patrick W Sheehan, Melvin W King, G Travis Tabor, Young Ah Goo, Mitchell A Lazar, Leonard Petrucelli, Erik S Mu...> ;Nature Communications. 2023 Aug 25
• 1 citations
  Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.
  Sára Nemes, Paige E Logan, Mohit K Manchella, Nidhi S Mundada, Renaud La Joie, Angelina J Polsinelli, Dustin B Hammers, Robert A Koeppe, Tatiana M Foroud, Kelly N Nude...> ;Alzheimer's & Dementia. 2023 Nov 1
• 3 citations
  APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading.
  Chanung Wang, Aishwarya Nambiar, Michael R Strickland, Choonghee Lee, Samira Parhizkar, Alec C Moore, Erik S Musiek, Jason D Ulrich, David M Holtzman> ;The Journal of Clinical Investigation. 2023 Jul 17
• 12 citations
  An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
  Patrick W Sheehan, Collin J Nadarajah, Michael F Kanan, Jessica N Patterson, Brenna Novotny, Jennifer H Lawrence, Melvin W King, Logan Brase, Casey E Inman, Carla M Yu...> ;Neuron. 2023 Aug 2
• 7 citations
  Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes.
  Celia A McKee, Alexander J Polino, Melvin W King, Erik S Musiek> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 May 16
• 2 citations
  Lecanamab Ushers in a New Era of Anti-Amyloid Therapy for Alzheimer's Disease.
  Erik S Musiek, Eric McDade, David M Holtzman> ;Annals of Neurology. 2023 May 1
• 8 citations
  Targeting Sleep and Circadian Function in the Prevention of Alzheimer Disease.
  Erik S Musiek, Yo-El S Ju> ;JAMA Neurology. 2022 Sep 1
• 21 citations
  Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden.
  Celia A McKee, Jiyeon Lee, Yuqi Cai, Takashi Saito, Takaomi Saido, Erik S Musiek> ;Scientific Reports. 2022 Feb 2
• 16 citations
  Aducanumab for Alzheimer disease: the amyloid hypothesis moves from bench to bedside.
  Erik S. Musiek, Teresa Gomez-Isla, David M. Holtzman> ;The Journal of Clinical Investigation. 2021 Oct 15
• 18 citations
  Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing.
  Hannah Wilks, Andrew J Aschenbrenner, Brian A Gordon, David A Balota, Anne M Fagan, Erik Musiek, Joyce Balls-Berry, Tammie L S Benzinger, Carlos Cruchaga, John C Morri...> ;Journal of Clinical and Experimental Neuropsychology. 2021 Oct 1
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Journal Articles

• Possible Consequences of the Approval of a Disease-Modifying Therapy for Alzheimer Disease  
  Erik Musiek, MD, JAMA Neurology
• Circadian Clock Protein Rev-Erbα Regulates Neuroinflammation  
  Erik Musiek, MD, Proceedings of the National Academy of Sciences