JeffreyAAlexanderMD

Gastroenterology • Rochester, MN

Advanced Endoscopic Interventional, Esophagus Disease

Professor of Medicine, Mayo Medical School

Join to view full profile

Dr. Alexander is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Alexander's full profile

Already have an account?

Office
200 1st Street SW
Rochester, MN 55905
Is this information wrong?

Summary

I am a board certified gastroenterologist at the Mayo Clinic Rochester, MN. I am the head of the Mayo Rochester Esophageal Disease Clinic. My interests are in esophageal disease with a specific research interest in eosinophilic esophagitis. Our eosinophilic esophagitis group has published numerous articles on and has over twenty ongoing investigations into the diagnosis, etiology and treatment of eosinophilic esophagitis.

Mayo Edge: Food not always the cause of eosinophilic esophagitis

DEAR MAYO CLINIC: I was diagnosed with eosinophilic esophagitis

Eosinophilic Esophagitis - Jeffrey Alexander, M.D. - Mayo Clinic

Jeffrey Alexander, M.D. a gastroenterologist at Mayo Clinic specializing in eosinophilic esophagitis, discusses the etiology, symptoms and treatment of EoE

Education & Training

UPMC Medical EducationFellowship, Gastroenterology, 1986 - 1987
McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1982 - 1985
Wayne State University School of MedicineClass of 1982

Certifications & Licensure

WI State Medical License 2019 - 2025
AZ State Medical License 2002 - 2024
MN State Medical License 1998 - 2024
ND State Medical License 2019 - 2024
MI State Medical License 1987 - 2000
PA State Medical License 1985 - 1988
IL State Medical License 1982 - 1987
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Clinical Trials

Topical Steroid Treatment for Eosinophilic Esophagitis Start of enrollment: 2005 Nov 01
Completed
Phase 2
Trial of Montelukast in Eosinophilic Esophagitis Start of enrollment: 2007 Aug 01
Completed
Phase 1
Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity Index Start of enrollment: 2011 Jan 01
Unknown status
Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Start of enrollment: 2012 Mar 01
Withdrawn
Phase 1, Phase 2
Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)? Start of enrollment: 2013 Mar 01
Completed
Nasal Nitric Oxide Levels in Eosinophilic Esophagitis (EoE) Start of enrollment: 2013 Aug 01
Completed
Cytosponge and Dietary Therapy in EoE Start of enrollment: 2015 Nov 01
Completed
Not Applicable
Natural History of Eosinophilic Esophagitis Start of enrollment: 2017 Jun 19
Completed
Join now to see all

Publications & Presentations

PubMed

A novel blood-sensing capsule for rapid detection of upper GI bleeding: a prospective clinical trial.
Karl Akiki, Tala Mahmoud, Mohammad H Alqaisieh, Lea N Sayegh, Kristin E Lescalleet, Barham K Abu Dayyeh, Louis M Wong Kee Song, Mark V Larson, David H Bruining, Nayant...> ;Gastrointestinal Endoscopy. 2023 Dec 6
Development of a model to identify patients who do not need oesophageal biopsies when eosinophilic oesophagitis is suspected.
Amrit K Kamboj, Liang Yen Liu, June Tome, Diana L Snyder, Jeffrey A Alexander, Karthik Ravi, William S Harmsen, Evan S Dellon, David A Katzka, Cotton, C.> ;Alimentary Pharmacology & Therapeutics. 2023 Dec 1
Eosinophilic Esophagitis Histologic Scoring System: Correlation with Histologic, Endoscopic, and Symptomatic Disease and Clinical Use.
Karthik Ravi, Margaret H Collins, Crystal J Lavey, Diana L Snyder, Ryan J Lennon, Blake A Kassmeyer, David A Katzka, Jeffrey A Alexander, Ryan G Alexander> ;Digestive Diseases and Sciences. 2023 Sep 1
1 citations
Letter: diet-responsive or just diet-adherent in EoE. Where is the dietitian? Authors' reply.
Lillian Wang, Jeffrey A Alexander> ;Alimentary Pharmacology & Therapeutics. 2023 Feb 1
2 citations
Use of the Esophageal Sponge in Directing Food Reintroduction in Eosinophilic Esophagitis.
Jeffrey A Alexander, Karthik Ravi, Thomas C Symrk, Tsung-The Wu, Crystal J Lavey, Debra Geno, Alyssa J Johnson, Ryan J Lennon, Margaret H Collins, Evan S Dellon, David...> ;Clinical Gastroenterology and Hepatology. 2023 Feb 1
7 citations
Predictors of histologic response to dietary therapy in eosinophilic oesophagitis.
Lillian Wang, Kristin C Mara, Karthik Ravi, Tsung-Teh Wu, Thomas C Smyrk, David A Katzka, Jeffrey A Alexander> ;Alimentary Pharmacology & Therapeutics. 2022 Nov 1
1 citations
Eosinophil Peroxidase Staining Enhances the Diagnostic Utility of the Cytosponge in Eosinophilic Esophagitis.
Mia Y Masuda, Suzanne M Barshow, Shipra Garg, Arina Putikova, William E LeSuer, Jeffrey A Alexander, David A Katzka, Evan S Dellon, Hirohito Kita, Jennifer L Horsley-S...> ;Clinical and Translational Gastroenterology. 2022 Nov 1
16 citations
Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy Consensus Conference.
Seema S Aceves, Jeffrey A Alexander, Todd H Baron, Arjan J Bredenoord, Lukejohn Day, Evan S Dellon, Gary W Falk, Glenn T Furuta, Nirmala Gonsalves, Ikuo Hirano, Vani J...> ;Gastrointestinal Endoscopy. 2022 Oct 1
Histologic response to steroids in eosinophilic esophagitis is dependent on delivery compound.
Daniel A Schupack, Kimberly Johnson, Joseph A Akambase, Debra Geno, Crystal Lavey, Ryan J Lennon, Karthik Ravi, Diana L Snyder, David A Katzka, Jeffrey A Alexander> ;Diseases of the Esophagus. 2022 Dec 31
11 citations
Reliability and responsiveness of endoscopic disease activity assessment in eosinophilic esophagitis.
Christopher Ma, Albert J Bredenoord, Evan S Dellon, Jeffrey A Alexander, Luc Biedermann, Malcolm Hogan, Leonardo Guizzetti, Guangyong Zou, David A Katzka, Mirna Chehad...> ;Gastrointestinal Endoscopy. 2022 Jun 1
44 citations
International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.
Evan S Dellon, Nirmala Gonsalves, J Pablo Abonia, Jeffrey A Alexander, Nicoleta C Arva, Dan Atkins, Stephen E Attwood, Marcus K H Auth, Dominique D Bailey, Luc Biederm...> ;Clinical Gastroenterology and Hepatology. 2022 Nov 1
31 citations
Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS)
Christopher Ma, Alain M. Schoepfer, Evan S. Dellon, Albert J. Bredenoord, Mirna Chehade, Margaret H. Collins, Brian G. Feagan, Glenn T. Furuta, Sandeep K. Gupta, Ikuo ...> ;The Journal of Allergy and Clinical Immunology. 2021 Jul 6
6 citations
Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus
Christopher Ma, Alain M. Schoepfer, Ekaterina Safroneeva, Evan S. Dellon, Albert J. Bredenoord, Mirna Chehade, Margaret H. Collins, Brian G. Feagan, Glenn T. Furuta, S...> ;Gastroenterology. 2021 May 20
4 citations
Same-day opioid administration in opiate naïve patients is not associated with opioid-induced esophageal dysfunction (OIED).
Ryan A. Balko, David A. Katzka, Joseph A. Murray, Jeffrey A. Alexander, Kristin C. Mara, Karthik Ravi> ;Neurogastroenterology and Motility. 2021 May 1
11 citations
Mucosal penetration and clearance of gluten and milk antigens in eosinophilic oesophagitis.
Anupama Ravi, Eric V. Marietta, Jeffrey A. Alexander, Kathryn A. Peterson, Crystal Lavey, Debra M. Geno, Joseph A. Murray, David A. Katzka> ;Alimentary Pharmacology & Therapeutics. 2020 Dec 2
7 citations
Proton Pump Inhibitor Therapy in Eosinophilic Esophagitis: Predictors of Nonresponse
Ryan Alexander, Jeffrey A. Alexander, Joseph A. Akambase, William S. Harmsen, Debra M. Geno, Crystal Tholen, David A. Katzka, Karthik Ravi> ;Digestive Diseases and Sciences. 2021 Sep 1
12 citations
Effectiveness and Safety of High- vs Low-Dose Swallowed Topical Steroids for Maintenance Treatment of Eosinophilic Esophagitis: A Multicenter Observational Study.
Thomas Greuter, Anne Godat, Amit Ringel, Hector Samuel Almonte, Daniel A. Schupack, Gabriela N. Mendoza, Talaya McCright-Gill, Evan S. Dellon, Ikuo Hirano, Jeffrey A. ...> ;Clinical Gastroenterology and Hepatology. 2021 Dec 1
13 citations
Effect of Maintenance Therapy for Eosinophilic Esophagitis on Need for Recurrent Dilation.
Daniel A. Schupack, Karthik Ravi, Debra M. Geno, Katrina Pierce, Kristin C. Mara, David A. Katzka, Jeffrey A. Alexander> ;Digestive Diseases and Sciences. 2021 Feb 1
8 citations
Evaluating a combined bowel preparation for small-bowel capsule endoscopy: a prospective randomized-controlled study.
Stephanie L. Hansel, Joseph A. Murray, Jeffrey A. Alexander, David H. Bruining, Mark V. Larson, Thomas F. Mangan, Ross A. Dierkhising, Ann E. Almazar, Elizabeth Rajan> ;Gastroenterology Report. 2020 Feb 1
14 citations
Measurement of Observed Eating Behaviors in Patients With Active and Inactive Eosinophilic Esophagitis.
Ryan Alexander, Jeffrey A. Alexander, Karthik Ravi, Debra M. Geno, Crystal Tholen, Kristin C. Mara, David A. Katzka> ;Clinical Gastroenterology and Hepatology. 2019 Oct 1
23 citations
A decreased abundance of clostridia characterizes the gut microbiota in eosinophilic esophagitis.
Purna C. Kashyap, Stephen Johnson, Debra M. Geno, Heather Lekatz, Crystal Lavey, Jeffrey A. Alexander, Jun Chen, David A. Katzka> ;Physiological Reports. 2019 Oct 1
16 citations
Penetration of the Esophageal Epithelium by Dust Mite Antigen in Patients With Eosinophilic Esophagitis
Anupama Ravi, Eric V. Marietta, Debra M. Geno, Jeffrey A. Alexander, Joseph A. Murray, David A. Katzka> ;Gastroenterology. 2019 Jul 1
2 citations
Eosinophilic Esophagitis Is Rarely Continually Symptomatic 10 Years After an Initial Treatment Course in Adults
Alexander Podboy, Crystal Lavey, Kristin C. Mara, Debra M. Geno, S. Khana, Karthik Ravi, David A. Katzka, J. A. Alexander> ;Digestive Diseases and Sciences. 2019 May 7
11 citations
Corrigendum: Food impaction: Etiology over 35 years and association with eosinophilic esophagitis (Diseases of the Esophagus (doy093) DOI: 10.1093/dote/doy093)
Charles J. Lenz, Cadman L. Leggett, David A. Katzka, Joseph J. Larson, Felicity Enders, J. A. Alexander> ;Diseases of the Esophagus. 2019 Apr 1
10 citations
Food impaction: etiology over 35 years and association with eosinophilic esophagitis.
C J Lenz, C Leggett, D A Katzka, J J Larson, F T Enders, J A Alexander> ;Diseases of the Esophagus. 2019 Apr 1
Join now to see all

Journal Articles

Comparison of Mucosal Impedance Measurements Throughout the Esophagus and Mucosal Eosinophil Counts in Endoscopic Biopsies in Eosinophilic Esophagitis
Jeffrey A Alexander, Karthik Ravi, Michael F Vaezi, David A Katzka, Gastrointestinal Endoscopy

Lectures

Mayo Clinic Gastroenterology and Hepatology Board Review
Mayo School of Continuous Professional Development, Wheeling, Illinois - 9/5/2013
Advancements in Technology and Understanding of Esophageal Diseases
Mayo School of Continuous Professional Development, Phoenix, Arizona - 1/11/2013
Mayo Clinic Gastroenterology and Hepatology Board Review
Mayo School of Continuous Professional Development, Chicago, Illinois - 9/6/2012

Press Mentions

Mayo Clinic Minute: What Is Eosinophilic Esophagitis and Why Is It Becoming More Common?March 31st, 2017
Mayo Clinic Q&A: Morning Sickness; GERD or Something More Serious?February 21st, 2017