JeffreySSagerMDMSc

Pulmonology • Santa Barbara, CA

Critical Care Medicine, Pulmonary Vascular Medicine

Jeffrey S Sager MD Medical Corporation

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Office
2428 Castillo Street
Suite D
Santa Barbara, CA 93105
Phone+1 805-845-1500

Fax+1 805-845-0333
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Summary

Board certified in Internal Medicine/Pulmonary Diseases/Critical Care Medicine.
Concierge Medicine/Pulmonary hypertension/Advanced Bronchoscopy

Education & Training

University of PennsylvaniaMSc, Clinical Epidemiology and Biostatistics , 2003 - 2005
University of Pennsylvania Health SystemFellowship, Pulmonary Disease and Critical Care Medicine, 2001 - 2004
Albert Einstein Healthcare NetworkResidency, Internal Medicine, 1998 - 2000
University of the WitwatersrandClass of 1995

Certifications & Licensure

CA State Medical License 2007 - 2025
PA State Medical License 1997 - 2008
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Top Doctors:LA Area Castle Connolly, 2013

Clinical Trials

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension Start of enrollment: 2008 May 01
Completed
Phase 3
ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis Start of enrollment: 2009 Jul 01
Terminated
Phase 3
Ventavis® Registry Protocol Start of enrollment: 2009 Mar 01
Terminated
Treatment of Pulmonary Hypertension Associated COPD With Inhaled Treprostinil-1 Start of enrollment: 2012 Dec 01
Completed
Phase 1
Beraprost-314d Added-on to Tyvaso® (BEAT) Start of enrollment: 2013 May 31
Completed
Phase 3
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis Start of enrollment: 2016 Feb 01
Withdrawn
Phase 2
Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE Start of enrollment: 2017 Feb 03
Completed
Phase 2, Phase 3
An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE Start of enrollment: 2016 Sep 15
Terminated
Phase 2, Phase 3
A Study of Ubenimex in Patients With Pulmonary Arterial Hypertension (WHO Group 1) Start of enrollment: 2016 Apr 01
Completed
Phase 2
Open-Label Extension Study of Ubenimex in Patients With Pulmonary Arterial Hypertension (WHO Group 1) Start of enrollment: 2016 Dec 01
Terminated
Phase 2
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction Start of enrollment: 2017 Aug 15
Terminated
Phase 3
Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF Start of enrollment: 2018 Jan 30
Terminated
Phase 3
ADAPT - A Patient Registry of the Real-world Use of Orenitram® Start of enrollment: 2017 Jul 18
Active, not recruiting
Study of Sotatercept in Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A011-13) Start of enrollment: 2022 Mar 18
Recruiting
Phase 3
A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) Start of enrollment: 2021 Dec 29
Recruiting
Phase 2
A Long-term Follow-up Study of Sotatercept for PAH Treatment (MK-7962-004/A011-12) Start of enrollment: 2021 May 12
Recruiting
Phase 3
A Study to Learn About How Well Riociguat Works, How Safe it is and How it is Used Under Real World Conditions in Patients in the United States Who Are Receiving Riociguat for High Blood Pressure in the Arteries That Carry Blood From the Heart to the Lungs (Pulmonary Arterial Hypertension, PAH) Start of enrollment: 2021 Jul 16
Active, not recruiting
Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH) Start of enrollment: 2021 Apr 05
Recruiting
Phase 2
A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2) Start of enrollment: 2021 Mar 15
Completed
Phase 2
Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis Start of enrollment: 2020 Mar 03
Completed
Phase 2
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension Start of enrollment: 2020 Jun 30
Recruiting
Phase 3
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients Start of enrollment: 2018 Aug 30
Recruiting
Phase 3
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension Start of enrollment: 2019 Sep 23
Enrolling by invitation
Phase 3
Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA) Start of enrollment: 2023 Dec 28
Recruiting
Phase 3
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Publications & Presentations

PubMed

Impact of the COVID-19 pandemic on chronic disease management and patient reported outcomes in patients with pulmonary hypertension: The Pulmonary Hypertension Associa...
Mayer, M., Badesch, D., Nielsen, K., Kawut, S., Bull, T., Ryan, J., Sager, J., Mazimba, S., Hemnes, A., Klinger, J., Runo, J., McConnell, J., De Marco, T., Chakinala, ...> ;Pulmonary Circulation. 2023 Apr 1
6 citations
Pulmonary artery compliance in different forms of pulmonary hypertension.
Amber McCormick, Amita Krishnan, David Badesch, Raymond L Benza, Todd M Bull, Teresa De Marco, Jeremy Feldman, Anna R Hemnes, Russel Hirsch, Evelyn Horn, Jaime Kennedy...> ;Heart. 2023 Jun 26
Erratum: Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: An analysis of the Pulmonary Hypert...
Hilary M DuBrock, Charles D Burger, Sonja D Bartolome, Jeremy P Feldman, David D Ivy, Erika B Rosenzweig, Jeffrey S Sager, Kenneth W Presberg, Stephen C Mathai, Matthe...> ;Pulmonary Circulation. 2022 Oct 1
3 citations
Prediction of patient outcomes through social determinants of health: The Pulmonary Hypertension Association Registry (PHAR) evaluation.
Dan Grinnan, Le Kang, Christine DeWilde, David Badesch, Raymond Benza, Todd Bull, Murali Chakinala, Teresa DeMarco, Jeremy Feldman, Hubert J Ford, James Klinger, John ...> ;Pulmonary Circulation. 2022 Jul 1
Corrigendum for health-related quality of life and hospitalizations in chronic thromboembolic pulmonary hypertension versus idiopathic pulmonary arterial hypertension:...
J Minhas, S P Narasimmal, T M Bull, T De Marco, J W Mc Connell, M R Lammi, T Thenappan, J P Feldman, J S Sager, D B Badesch, J J Ryan, D C Grinnan, D Zwicke, E M Horn,...> ;Pulmonary Circulation. 2022 Apr 1
1 citations
HIV-associated Pulmonary Arterial Hypertension: A Report from the Pulmonary Hypertension Association Registry.
Nicholas A Kolaitis, Matthew Lammi, Sula Mazimba, Jeremy Feldman, Wes McConnell, Jeffrey S Sager, Abhijit A Raval, Marc A Simon, Teresa De Marco> ;American Journal of Respiratory and Critical Care Medicine. 2022 May 1
4 citations
Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat.
Franck F Rahaghi, Vijay P Balasubramanian, Robert C Bourge, Charles D Burger, Murali M Chakinala, Michael S Eggert, Jean M Elwing, Jeremy Feldman, Christopher King, Ja...> ;Pulmonary Circulation. 2022 Apr 1
2 citations
Health-related quality of life and hospitalizations in chronic thromboembolic pulmonary hypertension versus idiopathic pulmonary arterial hypertension: an analysis fro...
Jasleen Minhas, Sai Prasanna Narasimmal, Todd M. Bull, Teresa De Marco, J.W. McConnell, Matthew R. Lammi, Thenappan Thenappan, Jeremy Feldman, Jeffrey Sager, David B. ...> ;Pulmonary Circulation. 2021 Oct 14
11 citations
Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: an analysis of the Pulmonary Hypertension As...
Hilary M. DuBrock, Charles D. Burger, Sonja Bartolome, Jeremy Feldman, D. Dunbar Ivy, Erika B. Rosenzweig, J.S. Sager, Kenneth W. Presberg, Stephen C. Mathai, Matthew ...> ;Pulmonary Circulation. 2021 Jun 6
9 citations
Clinical Differences and Outcomes between Methamphetamine-associated and Idiopathic Pulmonary Arterial Hypertension in the Pulmonary Hypertension Association Registry.
Nicholas A. Kolaitis, Roham T. Zamanian, Vinicio A. de Jesus Perez, David B. Badesch, Raymond L. Benza, Charles D. Burger, Murali M. Chakinala, Jean M. Elwing, Jeremy ...> ;Annals of the American Thoracic Society. 2021 Apr 1
9 citations
Prediction of Health-related Quality of Life and Hospitalization in Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry
Jeff Min, David B. Badesch, Murali M. Chakinala, Jean M. Elwing, Robert P. Frantz, Evelyn M. Horn, James R. Klinger, Matthew R. Lammi, Sula Mazimba, J.S. Sager, Oksana...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Mar 15
7 citations
Obesity in pulmonary arterial hypertension the pulmonary hypertension association registry
Jeff Min, Rui Feng, David B. Badesch, Erika Berman-Rosenzweig, Charles D. Burger, Murali M. Chakinala, Teresa De Marco, Jeremy Feldman, Anna R. Hemnes, Evelyn M. Horn,...> ;Annals of the American Thoracic Society. 2021 Feb 1
4 citations
Residence at moderately high altitude and its relationship with WHO Group 1 pulmonary arterial hypertension symptom severity and clinical characteristics: the Pulmonar...
Shoaib Fakhri, Kelly Hannon, Kelly Moulden, Ryan A. Peterson, Peter Hountras, Todd M. Bull, James P. Maloney, Teresa De Marco, D. Dunbar Ivy, Thenappan Thenappan, J.S....> ;Pulmonary Circulation. 2020 Nov 10
Age-related differences in hemodynamics and functional status in pulmonary arterial hypertension: Baseline results from the Pulmonary Hypertension Association Registry.
DesJardin JT, Kolaitis NA, Kime N, Kronmal RA, Benza RL, Elwing JM, Lammi MR, McConnell JW, Presberg KW, Sager JS, Shlobin OA, De Marco T, PHAR Investigators> ;The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2020-05-16
4 citations
Capillary Proliferation in Systemic-Sclerosis-Related Pulmonary Fibrosis: Association with Pulmonary Hypertension.
Atsuko Seki, Zafia Anklesaria, Rajeev Saggar, Mark W. Dodson, Kristin Schwab, Ming-Chang Liu, Deepshikha Charan Ashana, William D. Miller, Sitaram Vangala, Ariss Derho...> ;ACR Open Rheumatology. 2019 Mar 1
2 citations
Acute Laryngeal Dystonia Associated With Asenapine Use: A Case Report.
Nathaniel Collins, Jeffrey Sager> ;Journal of Clinical Psychopharmacology. 2017 Dec 1
8 citations
Recommendations for the clinical management of patients receiving macitentan for pulmonary arterial hypertension (PAH): A Delphi consensus document
Franck Rahaghi, Hassan Alnuaimat, Rana Awdish, Vijay Balasubramanian, Robert C. Bourge, Charles D. Burger, John Butler, C. Gregory Cauthen, Murali M. Chakinala, Bennet...> ;Pulmonary Circulation. 2017 Aug 22
Macitentan and morbidity and mortality in pulmonary arterial hypertension.
Pulido T, Adzerikho I, Channick RN, Delcroix M, Galie N, Ghofrani HA, Jansa P, Jing ZC, Le Brun FO, Mehta S, Mittelholzer CM, Perchenet L, Sastry BK, Sitbon O, Souza R...> ;N Engl J Med. 2013 Aug 29
40 citations
Pulmonary complications of cirrhosis.
C. Singh, J.S. Sager> ;The Medical Clinics of North America. 2009 Jul 1
75 citations
Wide Variation in Clinicians' Assessment of New York Heart Association/World Health Organization Functional Class in Patients With Pulmonary Arterial Hypertension
Darren B. Taichman, Michael D. McGoon, Michael O. Harhay, Chris Archer-Chicko, J.S. Sager, Meena Murugappan, Murali M. Chakinali, Harold I. Palevsky, Robert Gallop> ;Mayo Clinic Proceedings. 2009 Jul 1
67 citations
Outcomes using extracorporeal life support for adult respiratory failure due to status asthmaticus.
Mark E. Mikkelsen, Y. Joseph Woo, Jeffrey S. Sager, Barry D. Fuchs, Jason D. Christie> ;ASAIO Journal. 2009 Jan 1
11 citations
Emergency extracorporeal life support for asphyxic status asthmaticus.
Mark E. Mikkelsen, Meredith E Pugh, John Hansen-Flaschen, Y. Joseph Woo, Jeffrey S. Sager> ;Respiratory Care. 2007 Nov 1
32 citations
Association between elevated whole blood Epstein-Barr virus (EBV)-encoded RNA EBV polymerase chain reaction and reduced incidence of acute lung allograft rejection.
Vivek N. Ahya, Lisa P. Douglas, Charalambos Andreadis, Sharon Arnoldi, Jakub Svoboda, Robert M. Kotloff, Denis Hadjiliadis, J.S. Sager, Y. Joseph Woo, Alberto Pochetti...> ;The Journal of Heart and Lung Transplantation. 2007 Aug 1
6 citations
Surgical Therapies for Pulmonary Arterial Hypertension
Jeffrey S. Sager, Vivek N. Ahya> ;Clinics in Chest Medicine. 2007 Mar 1
17 citations
Association of clinical risk factors with functional status following lung transplantation.
J.S. Sager, Robert M. Kotloff, Vivek N. Ahya, Denis Hadjiliadis, R. Simcox, Nancy P. Blumenthal, J. Mendez, Warren B. Bilker, Alberto Pochettino, Jason D. Christie> ;American Journal of Transplantation. 2006 Sep 1
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