JohnRJacobsenMD

PubMed

• Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.
  McKinnell RM, Klein U, Linsell MS, Moran EJ, Nodwell MB, Pfeiffer JW, Thomas GR, Yu C, Jacobsen JR> ;Bioorg. Med. Chem. Lett.. 2014-07-01
• Multivalent design of long-acting β(2)-adrenoceptor agonists incorporating biarylamines.
  Jacobsen JR, Aggen JB, Church TJ, Klein U, Pfeiffer JW, Pulido-Rios TM, Thomas GR, Yu C, Moran EJ> ;Bioorg. Med. Chem. Lett.. 2014-06-15
• 23 citations
  A multivalent approach to the discovery of long-acting β 2- adrenoceptor agonists for the treatment of asthma and COPD
  Jacobsen John R, Seok-Ki Choi, Jesse D. Combs, Eric Fournier, Uwe Klein, Juergen W. Pfeiffer, G. Roger Thomas, Cecile Yu, Edmund J. Moran> ;Bioorganic & Medicinal Chemistry Letters. 2012 Jan 15
• 9 citations
  Third-generation long-acting β2-adrenoceptor agonists: medicinal chemistry strategies employed in the identification of once-daily inhaled β2-adrenoceptor agonists
  John R Jacobsen> ;Future Medicinal Chemistry. 2011 Sep 23
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