Nikhil Ishwar Khushalani MD

Oncology•Tampa, FL

Hematologic Oncology, Melanoma

Senior Member (Tenured), Moffitt Cancer Center

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Moffitt Cancer Center, Division of Cutaneous Oncology10920 N. McKinley DriveTampa, FL 33612
Book by Phone+1(484) 929-2974
Fax+1 813-449-8584

Education & Training

University at BuffaloFellowship, Hematology and Medical Oncology, 1999 - 2002
University at BuffaloResidency, Internal Medicine, 1996 - 1999
Topiwala National Medical CollegeClass of 1995

Certifications & Licensure

FL State Medical License 2015 - 2026
NY State Medical License 2006 - 2016
American Board of Internal Medicine Medical Oncology

Clinical Trials

Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer Start of enrollment: 2006 Nov 01
Completed
Phase 2
Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer Start of enrollment: 2007 May 01
Terminated
Phase 1
Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer Start of enrollment: 2006 Nov 01
Completed
Phase 1
Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer Start of enrollment: 2008 May 01
Terminated
Phase 2
Study for Determination of Feasibility and Toxicity of Pre-Treatment With HPPH (2-1[1-Hexyloxyethyl]-2 Devinyl Pyropheophorbide-a) Photodynamic Therapy Prior to Chemoradiation in Non-Operable Patients With Obstructive Esophageal Cancer Start of enrollment: 2009 Dec 01
Withdrawn
Not Applicable
Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer Start of enrollment: 2010 Sep 01
Completed
Phase 2
Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery Start of enrollment: 2011 Jan 18
Completed
Phase 2
Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery Start of enrollment: 2012 Jan 01
Terminated
Phase 2
Safety and Efficacy of LEE011 and LGX818 in Patients With BRAF Mutant Melanoma. Start of enrollment: 2013 Jul 01
Terminated
Phase 1, Phase 2
Randomized Phase II Study of AB (Abraxane™, Bevacizumab) Versus Ipilimumab for 1st Line Therapy of Unresectable Stage IV Metastatic Malignant Melanoma (BRAF V600E Negative) Start of enrollment: 2013 Oct 01
Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery Start of enrollment: 2013 Oct 18
Completed
Phase 2
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Start of enrollment: 2014 Jul 11
ACTIVE_NOT_RECRUITING
PHASE2, PHASE3
Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer Start of enrollment: 2016 Aug 01
Completed
Phase 1, Phase 2
Avadomide (CC-122) in Combination With Nivolumab in Advanced Melanoma Start of enrollment: 2019 May 14
Completed
Phase 2
Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Study Start of enrollment: 2020 Jan 30
Withdrawn
Early Phase 1
IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma Start of enrollment: 2023 Oct 31
RECRUITING
PHASE2, PHASE3
Roles: Contact
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Publications & Presentations

PubMed

Validation of the Functional Assessment of Cancer Therapy - Immune Checkpoint Modulator 17-Item Symptom Index (FACT-ICM-17) to facilitate implementation in research an...
Lisa M Gudenkauf, Danielle B Tometich, Aasha I Hoogland, Xiaoyin Li, Kedar Kirtane
Cancer. 2025-10-15
3 citations
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy.
Erez N Baruch, Frederico O Gleber-Netto, Priyadharsini Nagarajan, Xiayu Rao, Shamima Akhter
Nature. 2025-10-01
Publisher Correction: Anti-PD-1 therapy in unresectable desmoplastic melanoma: the phase 2 SWOG S1512 trial.
Kari L Kendra, Shay L Bellasea, Zeynep Eroglu, Siwen Hu-Lieskovan, Katie M Campbell
Nature Medicine. 2025-08-26

Journal Articles

Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain
Kim Margolin, Omid Hamid, Christopher D Lao, Anna C Pavlick, Michael A Postow, F Stephen Hodi, Nikhil I Khushalani, Marc S Ernstoff, Hussein A Tawbi, Igor Puzanov, Ahm..., The New England Journal of Medicine
PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma
Jade Homsi, Michael R Migden, Nikhil I Khushalani, The New England Journal of Medicine
Malignant Adnexal Tumors of the Skin: A Single Institution Experience
Valerie Francescutti, Kilian Salerno, John 3rd Kane, Tolutope Oyasiji, Joseph Skitzki, Nikhil I Khushalani, BioMed Central

Lectures

CA045-001: A phase III, randomized, open label study of bempegaldesleukin (NKTR-214) plus nivolumab (NIVO) versus NIVO monotherapy in patients (pts) with previously un...
2019 ASCO Annual Meeting - 6/1/2019
Melanoma 2013: Standard Treatment, Novel Therapies, and Ongoing Controversies
Cvent Online Event Registration Software, Amherst, New York - 4/13/2013
13th Annual Radiation Oncology Conference for Therapists & Dosimetrists
Roswell Park Cancer Institute, Niagara Falls, New York - 9/6/2012

Press Mentions

Novel Immunotherapy Shows Early Promise in Melanoma Resistant to PD-1 BlockadeJuly 16th, 2025
Moffitt's 'Mole Patrol' Offers Free Skin Cancer ScreeningsMay 1st, 2022
Rationale for Combining a Modified IL-2 and Nivolumab in MelanomaJuly 8th, 2019
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Nikhil Ishwar Khushalani MD

Overview of Dr. Khushalani

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

Press Mentions

Insurance Accepted

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