OladapoOYekuMD,PhD, FACP

PubMed

• High-Grade Endometrial Cancer: Molecular Subtypes, Current Challenges, and Treatment Options.
  Yusuke Matoba, Lara Milane, Bo R Rueda, Kyle M Devins, William B Manning, Varvara Mazina, Oladapo O Yeku> ;Reproductive Sciences. 2024 Apr 24
• Phase 1/2 study of combined BCL-xL and MEK inhibition with navitoclax and trametinib in KRAS or NRAS mutant advanced solid tumors.
  Corcoran, R., Do, K., Kim, J., Cleary, J., Parikh, A., Yeku, O., Xiong, N., Weekes, C., Veneris, J., Ahronian, L., Mauri, G., Tian, J., Norden, B., Michel, A., Van Sev...> ;Clinical Cancer Research. 2024 Mar 8
• Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma.
  Yusuke Matoba, Dominique T Zarrella, Venkatesh Pooladanda, Maryam Azimi Mohammadabadi, Eugene Kim, Shaan Kumar, Mengyao Xu, Xingping Qin, Lauren J Ray, Kyle M Devins, ...> ;British Journal of Cancer. 2024 Mar 4
• Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
  Wang, Y., Gao, B., Zhang, L., Wang, X., Zhu, X., Yang, H., Zhang, F., Zhu, X., Zhou, B., Yao, S., Nagayama, A., Lee, S., Ouyang, J., Koh, S., Eisenhauer, E., Zarrella,...> ;Nature Communications. 2024 Feb 21
• Structural basis for antibody recognition of the proximal MUC16 ectodomain.
  Kwangkook Lee, Kay Perry, Mengyao Xu, Irva Veillard, Raj Kumar, Thapi Dharma Rao, Bo R Rueda, David R Spriggs, Oladapo O Yeku> ;Journal of Ovarian Research. 2024 Feb 19
• Racial disparities and referral for genetic counseling.
  Oladapo O Yeku> ;Cancer. 2024 Feb 15
• 2 citations
  Phase IIa Study of PLX2853 in Gynecologic Cancers With Known ARID1A Mutation and Phase Ib/IIa Study of PLX2853/Carboplatin in Platinum-Resistant Epithelial Ovarian Can...
  Linda R Duska, Dmitriy Zamarin, Erica Hamilton, Amit Oza, Gini Fleming, Alexander Spira, Oladapo O Yeku, Debra L Richardson, Jackie Walling, Kerry Inokuchi, Bernice Ma...> ;JCO Precision Oncology. 2023 Sep 1
• 1 citations
  Combination Therapy, Including Bevacizumab, for Advanced Colorectal Cancer.
  Oladapo O Yeku, Dan L Longo> ;The New England Journal of Medicine. 2023 May 4
• Intraperitoneal Therapy for Ovarian Cancer - Some Answers, More Questions, and Missed Opportunities.
  Yeku, O.> ;NEJM Evidence. 2023 May 1
• 3 citations
  CAR T Cells for Neuroblastoma.
  Oladapo O Yeku, Dan L Longo> ;The New England Journal of Medicine. 2023 Apr 6
• 1 citations
  Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors.
  Antonio Jimeno, Joaquina Baranda, Wade T Iams, Jong Chul Park, Monica Mita, Michael S Gordon, Matthew Taylor, Neesha Dhani, Alexis D Leal, Prakash Neupane, Cathy Eng, ...> ;Investigational New Drugs. 2023 Apr 1
• 17 citations
  A Phase II, Two-Stage Study of Letrozole and Abemaciclib in Estrogen Receptor-Positive Recurrent Endometrial Cancer.
  Kolin, D., Kolin, D., Panagiotis A Konstantinopoulos, Elizabeth K Lee, Niya Xiong, Carolyn Krasner, Susana Campos, David L Kolin, Joyce F Liu, Neil Horowitz, Alexi A W...> ;Journal of Clinical Oncology. 2023 Jan 20
• 12 citations
  Evaluation of Treatment With Talazoparib and Avelumab in Patients With Recurrent Mismatch Repair Proficient Endometrial Cancer.
  Panagiotis A Konstantinopoulos, Allison A Gockley, Niya Xiong, Carolyn Krasner, Neil Horowitz, Susana Campos, Alexi A Wright, Joyce F Liu, Meghan Shea, Oladapo Yeku, C...> ;JAMA Oncology. 2022 Sep 1
• 97 citations
  A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov...
  Bradley J Monk, Christine Parkinson, Myong Cheol Lim, David M O'Malley, Ana Oaknin, Michelle K Wilson, Robert L Coleman, Domenica Lorusso, Paul Bessette, Sharad Ghaman...> ;Journal of Clinical Oncology. 2022 Dec 1
• Dual Fluorescence Isogenic Synthetic Lethal Kinase Screen and High-Content Secondary Screening for MUC16/CA125-Selective Agents.
  Thapi D Rao, Mengyao Xu, Stephanie Eng, Guangli Yang, Robin Manson, Nestor Rosales, Raj Kumar, Irva E Veillard, Qin Zhou, Alexia Iasonos, Ouathek Ouerfelli, Hakim Djab...> ;Molecular Cancer Therapeutics. 2022 May 4
• 2 citations
  Effect of Mismatch Repair Status on Outcome of Early-Stage Grade 1 to 2 Endometrial Cancer Treated With Vaginal Brachytherapy.
  Andrea L. Russo, Larissa J. Lee, Jennifer Y. Wo, Andrzej Niemierko, Diane Park, Gabriela Alban, Martin T. King, Lauren Philp, Whitfield B. Growdon, Esther Oliva, David...> ;American Journal of Clinical Oncology. 2021 Nov 25
• Case 15-2021: A 76-Year-Old Woman with Nausea, Diarrhea, and Acute Kidney Failure
  Oladapo Yeku, Arielle Medford, Andrew Z. Fenves, Sacha N. Uljon> ;The New England Journal of Medicine. 2021 May 19
• 21 citations
  Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
  Oladapo Yeku, Thapi Dharma Rao, Ian Laster, Artem Kononenko, Terence J. Purdon, Pei Wang, Ziyou Cui, Hong Liu, Renier J. Brentjens, David R. Spriggs> ;Frontiers in Immunology. 2021 Apr 14
• 17 citations
  Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies.
  Marina Stasenko, E. Smith, Oladapo Yeku, Kay J. Park, Ian Laster, Kwangkook Lee, Sven Walderich, Elizabeth L. Spriggs, Bo R. Rueda, Britta Weigelt, Dmitriy Zamarin, Th...> ;Scientific Reports. 2021 Feb 12
• 70 citations
  Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages
  Mei Song, Oladapo Yeku, Sarwish Rafiq, Terence J. Purdon, Xue Dong, Lijing Zhu, Tuo Zhang, Huan Wang, Ziqi Yu, Junhua Mai, Haifa Shen, Briana G. Nixon, Ming O. Li, Ren...> ;Nature Communications. 2020 Dec 8
• 10 citations
  A phase 2 study of combined chemo-immunotherapy with cisplatin-pembrolizumab and radiation for unresectable vulvar squamous cell carcinoma
  Oladapo Yeku, Andrea L. Russo, Hang Lee, David R. Spriggs> ;Journal of Translational Medicine. 2020 Sep 14
• 1 citations
  PD-1 Inhibitor Therapy in a Patient with Preexisting P-ANCA Vasculitis: A Case Report and Review of the Literature.
  Amanda Ramos, Marcela G. del Carmen, Oladapo Yeku> ;Case Reports in Oncological Medicine. 2020 Aug 31
• 147 citations
  Armored CAR T-cells: utilizing cytokines and pro-inflammatory ligands to enhance CAR T-cell anti-tumour efficacy
  Oladapo Yeku, Renier J. Brentjens> ;Biochemical Society Transactions. 2016 Apr 15
• 207 citations
  Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System.
  Mauro P. Avanzi, Oladapo Yeku, Xinghuo Li, Dinali Wijewarnasuriya, Dayenne G. van Leeuwen, Kenneth Cheung, Hyebin Park, Terence J. Purdon, Anthony F. Daniyan, Matthew ...> ;Cell Reports. 2018 May 15
• 150 citations
  Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma
  Yanxia Zhao, Jinghong Cao, Alexander Melamed, Michael J. Worley, Allison Gockley, Dennis Jones, Hadi Tavakoli Nia, Yanling Zhang, Triantafyllos Stylianopoulos, Ashwin ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 18
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